Hyaluronic acid targets CD44 and inhibits FcεRI signaling involving PKCδ, Rac1, ROS, and MAPK to exert anti-allergic effect

Molecular Immunology

Volumn 45, Issue 9, 2008, Pages 2537-2547

  Kim, Youngmi ^a   Lee, Yun Sil ^b   Hahn, Jang Hee ^a   Choe, Jongseon ^a   Kwon, Hyung Joo ^c   Ro, Jai Youl ^d   Jeoung, Dooil ^a  

^a Kangwon National University   (South Korea)

^b Korea Institute of Radiation and Medical Science   (South Korea)

^c Sungkyunkwan University   (South Korea)

^d Hallym University   (South Korea)

Author keywords

Anti allergic effect; CD44; Fc RI; HA

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; BETA HEXOAMINIDASE; ENZYME; FC EPSILON RECEPTOR I; G PROTEIN COUPLED RECEPTOR; HERMES ANTIGEN; HISTAMINE; HYALURONIC ACID; IMMUNOGLOBULIN E; IMMUNOGLOBULIN RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; PROTEIN P47; PROTEIN P67; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL PROLINE RICH PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN FUNCTION; ARTICLE; ATOPIC DERMATITIS; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; HISTAMINE RELEASE; IMMUNOGLOBULIN BLOOD LEVEL; IN VIVO STUDY; LEUKEMIA CELL; MAST CELL LEUKEMIA; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKIN DEFECT;

ANIMALS; ANTIGENS, CD44; BETA-N-ACETYLHEXOSAMINIDASES; CHEMOKINES; DERMATITIS, ALLERGIC CONTACT; HISTAMINE RELEASE; HYALURONIC ACID; IMMUNOGLOBULIN E; INFLAMMATION; MAST CELLS; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN KINASE C-DELTA; RAC1 GTP-BINDING PROTEIN; RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, IGE; SIGNAL TRANSDUCTION;

MUS; RATTUS;

EID: 40849102303     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.01.008     Document Type: Article

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