High-molecular-weight hyaluronan inhibits macrophage proliferation and cytokine release in the early wound of a preclinical postlaminectomy rat model

Spine Journal

Volumn 6, Issue 5, 2006, Pages 550-556

  Schimizzi, Aimee L ^a   Massie, Jennifer B ^a   Murphy, Mark ^a   Perry, Andrew ^a   Kim, Choll W ^a   Garfin, Steven R ^a   Akeson, Wayne H ^a  

^a VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Cytokines; Hyaluronan; Laminectomy; Macrophages; Spine

Indexed keywords

CELL SURFACE RECEPTOR; CHROMOGENIC SUBSTRATE; DIAMINOBENZIDINE; HYALURONIC ACID; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CELL INFILTRATION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DILUTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIDURAL SPACE; EXTRACELLULAR MATRIX; FIBROSIS; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; LAMINECTOMY; MACROPHAGE; MALE; MICROENVIRONMENT; MOLECULAR WEIGHT; MONOCYTE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RANDOMIZATION; RAT; REVIEW; SCAR FORMATION; SPINAL NERVE; SURGICAL WOUND; SURVIVAL; VERTEBRA DISLOCATION; WOUND HEALING;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL PROLIFERATION; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROSIS; HYALURONIC ACID; IMMUNOENZYME TECHNIQUES; INTERVERTEBRAL DISK; LAMINECTOMY; LUMBAR VERTEBRAE; MACROPHAGES; MALE; MOLECULAR WEIGHT; POSTOPERATIVE COMPLICATIONS; RATS; RATS, SPRAGUE-DAWLEY; WOUND HEALING;

EID: 33747616464     PISSN: 15299430     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.spinee.2005.12.005     Document Type: Review

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