An essential role of mast cells in the development of airway hyperresponsiveness in a murine asthma model

Journal of Immunology

Volumn 164, Issue 7, 2000, Pages 3855-3861

  Kobayashi, Tetsuto ^a   Miura, Toru ^a   Haba, Tomoko ^a   Sato, Miyuki ^a   Serizawa, Isao ^a   Nagai, Hiroichi ^b   Ishizaka, Kimishige ^c  

^a KIRIN BREWERY CO LTD   (Japan)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^c LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE ANTIBODY; IMMUNOGLOBULIN E; INTERLEUKIN 5; OVALBUMIN;

ALLERGY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; EOSINOPHILIA; INFLAMMATION; MALE; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST;

EID: 0034177877     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.7.3855     Document Type: Article

References (38)

1. Azzawi, M., B. Bradley, P. K. Jeffery, A. J. Frew, A. J. Wardlaw, G. Knowles, B. Assoufi, J. V. Collins, S. Durham, and A. B. Kay. 1990. Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am. Rev. Respir. Dis. 142:1407.
2. Kay, A. B. 1991. Asthma and inflammation. J. Allergy Clin. Immunol. 87:893.
3. Djukanovic, R., J. W. Wilson, K. M. Britten, S. J. Wilson, A. F. Walls, W. R. Roche, P. H. Howarth, and S. T. Holgate. 1990. Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry. Am. Rev. Respir. Dis. 142: 863.
4. Pesci, A., A. Foresi, G. Bertorelli, A. Chetta, and D. Oliveri. 1993. Histochemical characteristics and degranulation of mast cells in epithelium and lamina propria of bronchial biopsies from asthmatic and normal subjects. Am. Rev. Respir. Dis. 147:684.
5. Drazen, J. M., J. P. Arm, and K. F. Austen. 1996. Sorting out the cytokines of asthma. J. Exp. Med. 183:1.
6. Lee, N. A., and J. J. Lee. 1997. Asthma: does IL-5 have a more provocative role? Am. J. Respir. Cell Mol. Biol. 16:497.
7. Foster, P. S., S. P. Hogan, A. J. Ramsay, K. I. Matthaei, and I. G. Young. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med. 183:195.
8. Corry, D. B., H. G. Folkesson, M. L. Warnock, D. J. Erle, M. A. Matthay, J. P. Wiener-Kronish, and R. M. Locksley. 1996. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J. Exp. Med. 183:109.
9. Metcalfe, D. D., M. Kaliner, and M. A. Donlon. 1981. The mast cell. Crit. Rev. Immunol. 3:23.
10. Schwartz, L. B., and K. F. Austen. 1984. Structure and function of the chemical mediators of mast cells. Prog. Allergy 34:271.
11. Ishizaka, T., and K. Ishizaka. 1984. Activation of mast cells for mediator release through IgE receptors. Prog. Allergy 34:188.
12. Redington, A. E., R. Polosa, A. F. Walls, P. H. Howarth, and S. T. Holgate. 1995. Role of mast cells and basophils in asthma. Chem. Immunol. 62:22.
13. Rossi, G. L., and D. Olivieri. 1997. Does the mast cell still have a key role in asthma? Chest 112:523.
14. Schumacher, J. H., A. O'Garra, B. Shrader, A. van Kimmenade, M. W. Bond, T. R. Mosmann, and R. L. Coffman. 1988. The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent. J. Immunol. 141:1576.
15. Hirano, T., H. Miyajima, H. Kitagawa, N. Watanabe, M. Azuma, O. Taniguchi, H. Hashimoto, S. Hirose, H. Yagita, S. Furusawa, Z. Ovary, and K. Okumura. 1988. Studies on murine IgE with monoclonal antibodies. I. Characterization of rat monoclonal anti-IgE antibodies and the use of these antibodies for determinations of serum IgE levels and for anaphylactic reactions. Int. Arch. Allergy Appl. Immunol. 85:47.
16. Konzett, H., and R. Rössler. 1940. Versuchsanordnung zu Untersuchungen an der Bronchialmuskultur. Ann. Exp. Path. Pharmacol. 195:71.
17. Kung, T. T., D. Stelts, J. A. Zurcher, H. Jones, S. P. Umland, W. Kretner, R. W. Egan, and R. W. Chapman. 1995. Mast cells modulate allergic pulmonary eosinophilia in mice. Am. J. Respir. Cell Mol. Biol. 12:404.
18. Tomura, T., H. Watarai, N. Honma, M. Sato, A. Iwamatsu, Y. Kato, R. Kuroki, T. Nakano, T. Mikayama, and K. Ishizaka. 1999. Immunosuppressive activities of recombinant glycosylation-inhibiting factor mutants. J. Immunol. 162:195.
19. Suzuki, N., T. Horiuchi, K. Ohta, M. Yamaguchi, T. Ueda, H. Takizawa, K. Hirai, J. Shiga, K. Ito, and T. Miyamoto. 1993. Mast cells are essential for the full development of silica-induced pulmonary inflammation: A study with mast cell-deficient mice. Am. J. Respir. Cell Mol. Biol. 9:475.
20. Gleich, G. J. 1990. The eosinophil and bronchial asthma: Current understanding. J. Allergy Clin. Immunol. 85:422.
21. Kay, A. B., and C. J. Corrigan. Eosinophils and neutrophils. 1992. Br. Med. Bull. 48:51.
22. Takeda, K., E. Hamelmann, A. Joetham, L. D. Shultz, G. L. Larsen, C. G. Irvin, and E. W. Gelfand. 1997. Development of eosinophilic airway inflammation and airway hyperresponsiveness in mast cell-deficient mice. J. Exp. Med. 186:449.
23. Nagai, H., S. Yamaguchi. Y. Maeda, and H. Tanaka. 1996. Role of mast cells, eosinophils and IL-5 in the development of airway hyperresponsiveness in sensitized mice. Clin. Exp. Allergy 26:642.
24. d mice. Am. J. Pathol. 127:191.
25. Martin, T. R., T. Takeishi, H. R. Katz, K. F. Austen, J. M. Drazen, and S. J. Galli. 1993. Mast cell activation enhances airway responsiveness to methacholine in the mouse. J. Clin. Invest. 91:1176.
26. Oshiba, A., E. Hamelmann, K. Takeda, K. L. Bradley, J. E. Loader, G. L. Larsen, and E. W. Gelfand. 1996. Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice. J. Clin. Invest. 97:1398.
27. Stelts, D., R. W. Egan, A. Falcone, C. G. Garlisi, G. J. Gleich, W. Kreutner, T. T. Kung, D. K. Nahrebne, R. W. Chapman, and M. Minnicozzi. 1998. Eosinophils retain their granule major basic protein in a murine model of allergic pulmonary inflammation. Am. J. Respir. Cell Mol. Biol. 18:463.
28. Kroegel, C., T. Yukawa, G. Dent, P. Venge, K. F. Chung, and P. J. Barnes. 1989. Stimulation of degranulation from human eosinophils by platelet-activating factor. J. Immunol. 142:3518.
29. Bartemes, K. R., S. McKinney, G. J. Gleich, and H. Kita. 1999. Endogenous platelet-activating factor is critically involved in effector functions of eosinophils stimulated with IL-5 or IgG. J. Immunol. 162:2982.
30. Rubin, A-H. E., L. J. Smith, and R. Patterson. 1987. The bronchoconstrictor properties of platelet-activating factor in humans. Am. Rev. Respir. Dis. 136: 1145.
31. 4 and platelet-activating factor on airway reactivity in normal subjects. Am. Rev. Respir. Dis. 141:993.
32. 4 on the airway responsiveness to histamine in subjects with asthma and normal subjects. J. Allergy Clin. Immunol. 82:654.
33. 2 in the pathogenesis of airway hyperresponsiveness. Eur. Respir. J. 2:782.
34. Sekizawa, K., G. H. Caughey, S. C. Lazarus, W. M. Gold, and J. A. Nadel. 1989. Mast cell tryptase causes airway smooth muscle hyperresponsiveness in dogs. J. Clin. Invest. 83:175.
35. Molinari, J. F., M. Scuri, W. R. Moore, J. Clark, R. Tanaka, and W. M. Abraham. 1996. Inhaled tryptase causes bronchoconstriction in sheep via histamine release. Am. J. Respir. Crit. Care Med. 154:649.
36. Kung, T. T., D. M. Stelts, J. A. Zurcher, G. K. Adams III. R. W. Egan, W. Kreutner, A. S. Watnick, H. Jones, and R. W. Chapman. 1995. Involvement of IL-5 in a murine model of allergic pulmonary inflammation: Prophylactic and therapeutic effect of an anti-IL-5 antibody. Am. J. Respir. Cell Mol. Biol. 13:360.
37. Hogan, S. P., A. Mould, H. Kikutani, A. J. Ramsay, and P. S. Foster. 1997. Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J. Clin. Invest. 99:1329.
38. Lee, J. J., M. P. McGarry, S. C. Farmer, K. L. Denzler, K. A. Larson, P. E. Carrigan, I. E. Brenneise, M. A. Horton, A. Haczku, E. W. Gelfand, et al. 1997. Inlerleukin-5 expression in the lung epithelium of transgenic mice leads to pulmonary changes pathognomonic of asthma. J. Exp. Med. 185:2143.