Quantitative prediction of oral absorption of PEPT1 substrates based on in vitro uptake into Caco-2 cells

International Journal of Pharmaceutics

Volumn 354, Issue 1-2, 2008, Pages 104-110

  Shimizu, Rikako ^a   Sukegawa, Tomomi ^a   Tsuda, Yasuyuki ^a   Itoh, Tomoo ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

Lactam antibiotics; Caco 2 cells; Oral absorption; PEPT1; Prediction

Indexed keywords

BETA LACTAM ANTIBIOTIC; CEFIXIME; CEFOTIAM; CEFRADINE; GLYCYLSARCOSINE; PEPTIDE TRANSPORTER 1;

ARTICLE; DRUG ADSORPTION; DRUG CLEARANCE; DRUG SOLUBILITY; DRUG UPTAKE; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL;

ABSORPTION; ADMINISTRATION, ORAL; ANTI-BACTERIAL AGENTS; BETA-LACTAMS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CEFIXIME; CEFOTIAM; CEPHRADINE; DIPEPTIDES; FORECASTING; HUMANS; MODELS, BIOLOGICAL; SYMPORTERS;

EID: 40849092489     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.12.045     Document Type: Article

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