Expression and function of the purinergic receptor P2X7 in patients with pulmonary tuberculosis

Clinical and Experimental Immunology

Volumn 146, Issue 2, 2006, Pages 253-261

  Franco Martinez S ^a   Nino Moreno P ^a   Bernal Silva, S ^a   Baranda, L ^a   Rocha Meza, M ^b   Portales Cervantes, L ^a   Layseca Espinosa, E ^a   Gonzalez Amaro R ^a   Portales Perez D ^a,b  

^a UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

^b UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

Author keywords

Apoptosis; Lymphocytes; MAP kinases; P2X7; Tuberculosis

Indexed keywords

ADENOSINE TRIPHOSPHATE; LUCIFER YELLOW; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PURINE P2X7 RECEPTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; INTRACELLULAR KILLING; LEUKOCYTE ACTIVATION; LUNG TUBERCULOSIS; MALE; MYCOBACTERIUM TUBERCULOSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA ANALYSIS;

ADENOSINE TRIPHOSPHATE; ADOLESCENT; ADULT; AGED; APOPTOSIS; BLOTTING, WESTERN; CELLS, CULTURED; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; MALE; MIDDLE AGED; RECEPTORS, PURINERGIC P2; RECEPTORS, PURINERGIC P2X7; RNA, MESSENGER; TUBERCULOSIS, PULMONARY;

EID: 33750076053     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2006.03213.x     Document Type: Article

References (37)

1. World Health Organization. Global tuberculosis programme. Tuberculosis factsheet. Geneva: WHO. Available at: http://www.who.int/gtb/publication/ factsheet/index.html. (Last accessed 2005)
2. Kato-Maeda M, Bifani PJ, Kreiswirth BN, Small PM. The nature and consequence of genetic variability within Mycobacterium tuberculosis. J Clin Invest 2001; 107:533-7.
3. Chackerian AA, Perera TV, Behar SM. Gamma interferon-producing CD4+ T lymphocytes in the lung correlate with resistance to infection with Mycobacterium tuberculosis. Infect Immun 2001; 69:2666-74.
4. Serbina NV, Lazarevic V, Flynn JL. CD4(+) T cells are required for the development of cytotoxic CD8(+) T cells during Mycobacterium tuberculosis infection. J Immunol 2001; 167:6991-00.
5. Zhang M, Lin Y, Lyer DV, Gong J, Abrams JS, Barnes PF. T-cell cytokine responses in human infection with Mycobacterium tuberculosis. Infect Immun 1995; 63:3231-4.
6. Algood HM, Lin PL, Flynn JL. Tumor necrosis factor and chemokine interactions in the formation and maintenance of granulomas in tuberculosis. Clin Infect Dis 2005; 41:S189-93.
7. Lazarevic V, Nolt D, Flynn JL. Long-term control of Mycobacterium tuberculosis infection is mediated by dynamic immune responses. J Immunol 2005; 175:1107-17.
8. Keane J, Balcewicz-Sablinska MK, Remold HG et al. Infection by Mycobacterium tuberculosis promotes human alveolar macrophage apoptosis. Infect Immun 1997; 65:298-304.
9. Mancino G, Placido R, Di Virgilio F. P2X7 receptors and apoptosis in tuberculosis infection. J Biol Regul Homeost Agents 2001; 15:286-93.
10. Lammas DA, Stober C, Harvey CJ, Kendrick N, Panchalingam S, Kumararatne DS. ATP-induced killing of mycobacterium by human macrophages is mediated by purinergic P2Z (P2X7) receptor. J Immun 1997; 7:433-44.
11. Molloy A, Laochumroonvorapong P, Kaplan G. Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guérin. J Exp Med 1994; 180:1499-509.
12. Di Virgilio F, Chiozzi P, Ferrari D et al. Nucleotide receptors: an emerging family of regulatory molecules in blood cells. Blood 2001; 97:587-00.
13. North RA. Molecular physiology of P2X7 receptors. Physiol Rev 2002; 82:1013-67.
14. Lajdova I, Chorvat D Jr, Spustova V, Chorvatova A. 4-Aminopyridine activates calcium influx through modulation of the pore-forming purinergic receptor in human peripheral blood mononuclear cells. Can J Physiol Pharmacol 2004; 82:50-6.
15. Virginio C, MacKenzie A, North RA, Surprenant A. Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor. J Physiol 1999; 519:335-46.
16. Fairbairn IP, Stober CB, Kumararatne DS, Lammas DA. ATP-mediated killing of intracellular Mycobacterium by macrophages is a P2X7-dependent process inducing bacterial death by phagosome-lysosome fusion. J Immunol 2001; 167:3300-7.
17. Kusner DJ, Barton JA. ATP stimulates human macrophages to kill intracellular virulent Mycobacterium tuberculosis via calcium-dependent phagosome-lysosome fusion. J Immunol 2001; 167:3308-15.
18. Humphreys BD, Rice J, Kertesy SB, Dubyak GR. Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor. J Biol Chem 2000; 275:26792-8.
19. Auger R, Motta I, Benihoud K, Ojcius DM, Kanellopoulos JM. A role for mitogen-activated protein kinase (Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death. J Biol Chem 2005; 280:28142-51.
20. Kahlenberg JM, Dubyak GR. Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release. Am J Physiol Cell Physiol 2004; 286:C1100-8.
21. Labasi JM, Petrushova N, Donovan C et al. Absence of the P2X7 receptor alters leukocyte function and attenuates an inflammatory response. J Immunol 2002; 168:6436-45.
22. Saunders BM, Fernando SL, Sluyter R, Britton WJ, Wiley JS. A loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of Mycobacterium. J Immunol 2003; 171:5442-6.
23. Gu BJ, Zhang WY, Bendall LJ et al. Expression of P2X7 purinoceptors on human lymphocytes and monocytes: evidence for nonfunctional P2X7 receptors. Am J Physiol Cell Physiol 2000; 279:C1189-97.
24. Miller JS, Cervenka T, Lund J, Okazaki IJ, Moss J. Purine metabolites suppress proliferation of human NK cells through a lineage-specific purine receptor. J Immunol 1999; 162:7376-82.
25. Kawamura H, Aswad F, Minagawa M, Govindarajan S, Dennert G. P2X7 receptors regulate NKT cells in autoimmune hepatitis. J Immunol 2006; 176:2152-60.
26. Wiley JS, Dao-Ung LP, Gu BJ et al. A loss-of-function polymorphic mutation in the cytolytic P2X7 receptor gene and chronic lymphocytic leukemia: a molecular study. Lancet 2002; 359:1114-9.
27. Zhang XJ, Zheng GG, Ma XT, Lin YM, Song YH, Wu KF. Effects of various inducers on the expression of P2X7 receptor in human peripheral blood mononuclear cells. Sheng Li Xue Bao 2005; 57:193-8.
28. Fiorenza G, Rateni L, Farroni MA, Bogue C, Dlugovitzky DG. TNF-alpha, TGF-beta and NO relationship in sera from tuberculosis (TB) patients of different severity. Immunol Lett 2005; 98:45-8.
29. Olobo JO, Geletu M, Demissie A et al. Circulating TNF-alpha, TGF-beta, and IL-10 in tuberculosis patients and healthy contacts. Scand J Immunol 2001; 53:85-91.
30. Adinolfi E, Callegari MG, Ferrari D et al. Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth. Mol Biol Cell 2005; 16:3260-72.
31. Baricordi OR, Melchiorri L, Adinolfi E et al. Increased proliferation rate of lymphoid cells transfected with the P2X(7) ATP receptor. J Biol Chem 1999; 274:33206-8.
32. Chiozzi P, Sanz JM, Ferrari D et al. Spontaneous cell fusion in macrophage cultures expressing high levels of the P2Z/P2X7 receptor. J Cell Biol 1997; 138:697-06.
33. Di Virgilio F, Falzoni S, Chiozzi P, Sanz JM, Ferrari D, Buell GN. ATP receptors and giant cell formation. J Leukoc Biol 1999; 66:723-6.
34. Ke HZ, Qi H, Weidema AF et al. Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption. Mol Endocrinol 2003; 17:1356-67.
35. Shemon AN, Sluyter R, Fernando SL et al. A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages. J Biol Chem 2006; 281:2079-86.
36. Blumenthal A, Lauber J, Hoffmann R et al. Common and unique gene expression signatures of human macrophages in response to four strains of Mycobacterium avium that differ in their growth and persistence characteristics. Infect Immun 2005; 73:3330-41.
37. Myers AJ, Eilertson B, Fulton SA, Flynn JL, Canaday DH. The purinergic P2X7 receptor is not required for control of pulmonary Mycobacterium tuberculosis infection. Infect Immun 2005; 73:3192-5.