The orexigenic effect of melanin-concentrating hormone (MCH) is influenced by sex and stage of the estrous cycle

Physiology and Behavior

Volumn 93, Issue 4-5, 2008, Pages 842-850

  Santollo, Jessica ^a   Eckel, Lisa A ^a  

^a FLORIDA STATE UNIVERSITY   (United States)

Author keywords

Estradiol; Food intake; Locomotor activity; Meal size; Water intake

Indexed keywords

ESTRADIOL; ESTRADIOL BENZOATE; MELANIN CONCENTRATING HORMONE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ESTRUS CYCLE; FEMALE; FOOD INTAKE; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEXUAL BEHAVIOR;

EID: 40749138540     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2007.11.050     Document Type: Article

References (44)

1. Skofitsch G., Jacobowitz D.M., and Zamir N. Immunohistochemical localization of a melanin-concentrating-like hormone in the rat brain. Brain Res Bull 15 (1985) 635-649
2. Pissios P., Bradley R.L., and Maratos-Flier E. Expanding the scales: the multiple role of MCH in regulating energy balance and other biological functions. Endocr Rev 27 (2006) 606-620
3. Westerfield D.B., Pang P.K., and Burns J.M. Some characteristics of melanophore-concentrating horomone (MCH) from teleost pituitary glands. Gen Comp Endocrinol 42 (1980) 494-499
4. Clegg D.J., Air E.L., Benoit S.C., Sakai R.S., Seeley R.J., and Woods S.C. Intraventricular melanin-concentrating hormone stimulates water intake independent of food intake. Am J Physiol Regul Integr Comp Physiol 284 (2003) R494-R499
5. Abbott C.R., Kennedy A.R., Wren A.M., Rossi M., Murphy K.G., Seal L.J., et al. Identification of hypothalamic nuclei involved in the orexigenic effect of melanin-concentrating hormone. Endocrinology 144 (2003) 3943-3949
6. Qu D., Ludwig D.S., Gammeltoft S., Piper M., Pelleymounter M.A., Cullen M.J., et al. A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature 380 (1996) 243-247
7. Della-Zuana O., Presse F., Ortola C., Duhault J., Nahon J.L., and Levens N. Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats. Int J Obes Relat Metab Disord 26 (2002) 1289-1295
8. Shearman L.P., Camacho R.E., Sloan-Stribling D., Zhou D., Bednarek M.A., Hreniuk D.L., et al. Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats. Eur J Pharmacol 475 (2003) 37-47
9. Ludwig D.S., Tritos N.A., Mastaitis J.W., Kulkarni R., Kokkotou E., Elmquist J., et al. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J Clin Invest 107 (2001) 379-386
10. Morens C., Norregaard P., Receveur J., van Dijk G., and Scheurink A.J.W. Effects of MCH and MCH1-receptor antagonist on (palatable) food and water intake. Brain Res 1062 (2005) 32-38
11. Ito M., Gomori A., Ishihara A., Oda Z., Mashiko S., Matsushita H., et al. Characterization of MCH-mediated obesity in mice. Am J Physiol Endocrinol Metabol 284 (2003) E940-E945
12. Zheng H., Patterson L.M., Morrison C., Banfield B.W., Randall J.A., Browning K.N., et al. Melanin concentrating hormone innervation of caudal brainstem areas involved in gastrointestinal functions and energy balance. Neurosci 135 (2005) 611-625
13. Shimada M., Tritos N.A., Lowell B.B., Flier J.S., and Maratos-Flier E. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 396 (1998) 670-674
14. Zhou D., Shen Z., Strack A.M., Marsh D.J., and Shearman L.P. Enhanced running wheel activity of both Mch1r- and Pmch-deficient mice. Regul Pept 124 (2005) 53-63
15. Marsh D.J., Weingarth D.T., Novi D.E., Chen H.Y., Trumbauer M.E., Chen A.S., et al. Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism. Proc Natl Acad Sci U S A 99 (2002) 3240-3245
16. Smith G.P. The controls of eating: a shift from nutritional homeostasis to behavioral neuroscience. Nutrition 16 (2000) 814-820
17. Kowalski T.J., Farley C., Cohen-Williams M.E., Varty G., and Spar B.D. Melanin-concentrating hormone-1 receptor antagonism decreases feeding by reducing meal size. Eur J Pharmacol 497 (2004) 41-47
18. Messina M.M., Boersma G., Overton J.M., and Eckel L.A. Estradiol decreases the orexigenic effect of melanin-concentrating hormone in ovariectomized rats. Physiol Behav 88 (2006) 523-528
19. Paxinos G., and Watson C. The rat brain in stereotaxic coordinates. Fourth edition (1998), Academic Press, San Diego, CA
20. Eckel L.A., Houpt T.A., and Geary N. Spontaneous meal patterns in female rats with and without access to running wheels. Physiol Behav 70 (2000) 397-405
21. Asarian L., and Geary N. Cyclic estradiol treatment normalizes body weight and restores physiological patterns of spontaneous feeding and sexual receptivity in ovariectomized rats. Horm Behav 42 (2002) 461-471
22. Becker J.B., Arnold A.P., Berkley K.B., Blaustein J.D., Eckel L.A., Hampson E., et al. Strategies and methods for research on sex differences in brain and behavior. Endocrinology 146 (2005) 1650-1673
23. Rossi M., Choi S.J., O'Shea D., Miyoshi T., Ghatei M.A., and Bloom S.R. Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight. Endocrinology 138 (1997) 351-355
24. Tritos N.A., Vicent D., Gillette J., Ludwig D.S., Flier E.S., and Maratos-Flier E. Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus. Diabetes 47 (1998) 1687-1692
25. Shughrue P.J., Lane M.V., and Merchenthaler I. Comparative distribution of estrogen receptor-a and -b mRNA in the rat central nervous system. J Comp Neurol 388 (1997) 507-525
26. Murray J.F., Baker B.I., Levy A., and Wilson C.A. The influence of gonadal steroids on pre-pro melanin-concentrating hormone mRNA in female rats. J Neuroendocrinol 12 (2000) 53-59
27. Morton G.J., Mystkowski P., Matsumoto A.M., and Schwartz M.W. Increased hypothalamic melanin concentrating hormone gene expression during energy restriction involves a melanocortin-independent, estrogen sensitive mechanism. Peptides 25 (2004) 667-674
28. Tritos N.A., Segal-Lieberman G., Vezeridis P.S., and Maratos-Flier E. Estradiol-induced anorexia is independent of leptin and melanin-concentrating hormone. Obes Res 12 (2004) 716-724
29. Osterlund M., Kuiper G.G.J.M., Gustafsson J.A., and Hurd Y.L. Differential distribution and regulation of estrogen receptor-alpha and -beta mRNA within the female rat brain. Mol Brain Res 54 (1998) 175-180
30. Hervieu G.J., Cluderay J.E., Harrison D., Meakin J., Maycox P., Nasir S., et al. The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat. Eur J Neurosci 12 (2000) 1194-1216
31. Smith G.P. The direct and indirect controls of meal size. Neurosci Biobehav Rev 20 (1996) 41-46
32. Kokkotou E., Jeon J.Y., Wang X., Marino F.E., Carlson M., Trombly D.J., et al. Mice with MCH ablation resist diet-induced obesity through strain-specific mechanisms. Am J Physiol Regul Integr Comp Physiol 289 (2005) R117-R124
33. Segal-Lieberman G., Bradley R.L., Kokkotou E., Carlson M., Trombly D.J., Wang X., et al. Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype. Proc Natl Acad Sci U S A 100 (2003) 10085-10090
34. Astrand A., Bohlooly-Y M., Larsdotter S., Mahlapuu M., Anderson H., Tornell J., et al. Mice lacking melanin-concentrating hormone receptor 1 demonstrate increased heart rate associated with altered autonomic activity. Am J Physiol Regul Integr Comp Physiol 287 (2004) R749-R758
35. Jeon J.Y., Bradley R.L., Kokkotou E.G., Marino F.E., Wang X., Pissios P., et al. MCH-/- Mice are resistant to aging-associated increases in body weight and insulin resistance. Diabetes 55 (2006) 428-434
36. Messina M.M., and Overton J.M. Cardiovascular effects of melanin-concentrating hormone. Regul Pept 139 (2006) 23-30
37. Gomori A., Ishihara A., Ito M., Mashiko S., Matsushita H., Yumoto M., et al. Chronic intracerebroventricular infusion of MCH causes obesity in mice. Am J Physiol Endocrinol Metabol 284 (2003) E583-E588
38. Mashiko S., Ishihara A., Gomori A., Moriya M., Ito M., Iwaasa H., et al. Antiobesity effect of a melanin-concentrating hormone 1 receptor antagonist in diet-induced obese mice. Endocrinology 146 (2005) 3080-3086
39. Clegg D.J., Brown L.M., Kemp C.J., Strader A.D., Benoit S.C., Woods S.C., et al. Estradiol-dependent decreases in the orexigenic potency of ghrelin in female rats. Diabetes 56 (2007) 1051-1058
40. Eckel L.A., and Geary N. Endogenous cholecystokinin's satiating action increases during estrus in female rats. Peptides 20 (1999) 451-456
41. Eckel L.A., Rivera H.M., and Atchley D.P.D. The anorectic effect of fenfluramine is influenced by sex and stage of the estrous cycle in rats. Am J Physiol Regul Integr Comp Physiol 288 (2005) R1486-R1491
42. Geary N., and Asarian L. Estradiol increases glucagon's satiating potency in ovariectomized rats. Am J Physiol Regul Integr Comp Physiol 281 (2001) R1290-R1294
43. Butera P.C., Bradway D.M., and Cataldo N.J. Modulation of the satiety effect of cholecystokinin by estradiol. Physiol Behav 53 (1993) 1235-1238
44. Clegg D.J., Brown L.M., Woods S.C., and Benoit S.C. Gonadal hormones determine sensitivity to central leptin and insulin. Diabetes 55 (2006) 978-987