메뉴 건너뛰기




Volumn 22, Issue 3, 2008, Pages 578-584

HLA-G turns off erythropoietin receptor signaling through JAK2 and JAK2 V617F dephosphorylation: Clinical relevance in polycythemia vera

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN RECEPTOR; HLA G ANTIGEN; JANUS KINASE 2; PHENYLALANINE; STAT3 PROTEIN; STAT5 PROTEIN; VALINE;

EID: 40749134154     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2405050     Document Type: Article
Times cited : (27)

References (28)
  • 2
    • 8644289450 scopus 로고    scopus 로고
    • Erythroblasts secrete the nonclassical HLA-G molecule from primitive to definitive hematopoiesis
    • Menier C, Rabreau M, Challier JC, Le Discorde M, Carosella ED, Rouas-Freiss N. Erythroblasts secrete the nonclassical HLA-G molecule from primitive to definitive hematopoiesis. Blood 2004; 104: 3153-3160.
    • (2004) Blood , vol.104 , pp. 3153-3160
    • Menier, C.1    Rabreau, M.2    Challier, J.C.3    Le Discorde, M.4    Carosella, E.D.5    Rouas-Freiss, N.6
  • 3
    • 0028880455 scopus 로고
    • Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor
    • Wu H, Liu X, Jaenisch R, Lodish HF. Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell 1995; 83: 59-67.
    • (1995) Cell , vol.83 , pp. 59-67
    • Wu, H.1    Liu, X.2    Jaenisch, R.3    Lodish, H.F.4
  • 4
    • 14744299761 scopus 로고    scopus 로고
    • Turning cells red: Signal transduction mediated by erythropoietin
    • Richmond TD, Chohan M, Barber DL. Turning cells red: Signal transduction mediated by erythropoietin. Trends Cell Biol 2005; 15: 146-155.
    • (2005) Trends Cell Biol , vol.15 , pp. 146-155
    • Richmond, T.D.1    Chohan, M.2    Barber, D.L.3
  • 5
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005; 365: 1054-1061.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3    East, C.4    Fourouclas, N.5    Swanton, S.6
  • 6
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP, Staerk J, Delhommeau F, Lacout C et al A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005; 434: 1144-1148.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3    Staerk, J.4    Delhommeau, F.5    Lacout, C.6
  • 7
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase. JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ et al Activating mutation in the tyrosine kinase. JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005; 7: 387-397.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3    Ebert, B.L.4    Wernig, G.5    Huntly, B.J.6
  • 8
    • 20744460045 scopus 로고    scopus 로고
    • Identification of an acquired JAK2 mutation in polycythemia vera
    • Zhao R, Xing S, Li Z, Fu X, Li Q, Krantz SB et al. Identification of an acquired JAK2 mutation in polycythemia vera. J Biol Chem 2005; 280: 22788-22792.
    • (2005) J Biol Chem , vol.280 , pp. 22788-22792
    • Zhao, R.1    Xing, S.2    Li, Z.3    Fu, X.4    Li, Q.5    Krantz, S.B.6
  • 10
    • 0036786901 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of the myeloid neoplasms
    • Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood 2002; 100: 2292-2302.
    • (2002) Blood , vol.100 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 11
    • 33644512749 scopus 로고    scopus 로고
    • Evidence to support the role of HLA-G5 in allograft acceptance through induction of immunosuppressive/regulatory T cells
    • Le Rond S, Azema C, Krawice-Radanne I, Durrbach A, Guettier C, Carosella ED et al. Evidence to support the role of HLA-G5 in allograft acceptance through induction of immunosuppressive/regulatory T cells. J Immunol 2006; 176: 3266-3276.
    • (2006) J Immunol , vol.176 , pp. 3266-3276
    • Le Rond, S.1    Azema, C.2    Krawice-Radanne, I.3    Durrbach, A.4    Guettier, C.5    Carosella, E.D.6
  • 12
    • 0032526631 scopus 로고    scopus 로고
    • HLA-G isoforms produced by placental cytotrophoblasts and found in amniotic fluid are due to unusual glycosylation
    • McMaster M, Zhou Y, Shorter S, Kapasi K, Geraghty D, Lim KH et al. HLA-G isoforms produced by placental cytotrophoblasts and found in amniotic fluid are due to unusual glycosylation. J Immunol 1998; 160: 5922-5928.
    • (1998) J Immunol , vol.160 , pp. 5922-5928
    • McMaster, M.1    Zhou, Y.2    Shorter, S.3    Kapasi, K.4    Geraghty, D.5    Lim, K.H.6
  • 13
    • 0036643849 scopus 로고    scopus 로고
    • MICA triggering signal for NK cell tumor lysis is counteracted by HLA-G1-mediated inhibitory signal
    • Menier C, Riteau B, Carosella ED, Rouas-Freiss N. MICA triggering signal for NK cell tumor lysis is counteracted by HLA-G1-mediated inhibitory signal. Int J Cancer 2002; 100: 63-70.
    • (2002) Int J Cancer , vol.100 , pp. 63-70
    • Menier, C.1    Riteau, B.2    Carosella, E.D.3    Rouas-Freiss, N.4
  • 15
    • 0027321052 scopus 로고
    • Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7
    • Komatsu N, Yamamoto M, Fujita H, Miwa A, Hatake K, Endo T et al. Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7. Blood 1993; 82: 456-464.
    • (1993) Blood , vol.82 , pp. 456-464
    • Komatsu, N.1    Yamamoto, M.2    Fujita, H.3    Miwa, A.4    Hatake, K.5    Endo, T.6
  • 16
    • 0037866476 scopus 로고    scopus 로고
    • Critical role for P1 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation
    • Bouscary D, Pene F, Claessens YE, Muller O, Chretien S, Fontenay-Roupie M et al. Critical role for P1 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation. Blood 2003; 101: 3436-3443.
    • (2003) Blood , vol.101 , pp. 3436-3443
    • Bouscary, D.1    Pene, F.2    Claessens, Y.E.3    Muller, O.4    Chretien, S.5    Fontenay-Roupie, M.6
  • 17
    • 0036098154 scopus 로고    scopus 로고
    • Identification of the human erythropoietin receptor region required for Stat1 and Stat3 activation
    • Kirito K, Nakajima K, Watanabe T, Uchida M, Tanaka M, Ozawa K et al Identification of the human erythropoietin receptor region required for Stat1 and Stat3 activation. Blood 2002; 99: 102-110.
    • (2002) Blood , vol.99 , pp. 102-110
    • Kirito, K.1    Nakajima, K.2    Watanabe, T.3    Uchida, M.4    Tanaka, M.5    Ozawa, K.6
  • 18
    • 33644546402 scopus 로고    scopus 로고
    • JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders
    • Quentmeier H, MacLeod RA, Zaborski M, Drexler HG. JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders. Leukemia 2006; 20: 471-476.
    • (2006) Leukemia , vol.20 , pp. 471-476
    • Quentmeier, H.1    MacLeod, R.A.2    Zaborski, M.3    Drexler, H.G.4
  • 19
  • 20
    • 34447627350 scopus 로고    scopus 로고
    • TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations
    • Pardanani A, Hood J, Lasho T, Levine RL, Martin MB, Noronha G et al TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations. Leukemia 2007; 21: 1658-1668.
    • (2007) Leukemia , vol.21 , pp. 1658-1668
    • Pardanani, A.1    Hood, J.2    Lasho, T.3    Levine, R.L.4    Martin, M.B.5    Noronha, G.6
  • 21
  • 22
    • 33746547247 scopus 로고    scopus 로고
    • The biology of interleukin-2 and interleukin-15: Implications for cancer therapy and vaccine design
    • Waldmann TA. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat Rev Immunol 2006; 6: 595-601.
    • (2006) Nat Rev Immunol , vol.6 , pp. 595-601
    • Waldmann, T.A.1
  • 23
    • 33847351136 scopus 로고    scopus 로고
    • The JAK-STAT signaling pathway: Input and output integration
    • Murray PJ. The JAK-STAT signaling pathway: Input and output integration. J Immunol 2007; 178: 2623-2629.
    • (2007) J Immunol , vol.178 , pp. 2623-2629
    • Murray, P.J.1
  • 24
    • 33748684367 scopus 로고    scopus 로고
    • The JAK2-V617F mutation is frequently present at diagnosis in patients with essential thrombocythemia and polycythemia vera
    • Lippert E, Boissinot M, Kralovics R, Girodon F, Dobo I, Praloran V et al. The JAK2-V617F mutation is frequently present at diagnosis in patients with essential thrombocythemia and polycythemia vera. Blood 2006; 108: 1865-1867.
    • (2006) Blood , vol.108 , pp. 1865-1867
    • Lippert, E.1    Boissinot, M.2    Kralovics, R.3    Girodon, F.4    Dobo, I.5    Praloran, V.6
  • 25
    • 12844271547 scopus 로고    scopus 로고
    • Increased erythropoiesis in poly-cythemia vera is associated with increased erythroid progenitor proliferation and increased phosphorylation of Akt/PKB
    • Dai C, Chung IJ, Krantz SB. Increased erythropoiesis in poly-cythemia vera is associated with increased erythroid progenitor proliferation and increased phosphorylation of Akt/PKB. Exp Hematol 2005; 33: 152-158.
    • (2005) Exp Hematol , vol.33 , pp. 152-158
    • Dai, C.1    Chung, I.J.2    Krantz, S.B.3
  • 26
    • 33746059048 scopus 로고    scopus 로고
    • High molecular response rate of polycythemia vera patients treated with pegylated interferon alpha-2a
    • Kiladjian JJ, Cassinat B, Turlure P, Cambier N, Roussel M, Bellucci S et al. High molecular response rate of polycythemia vera patients treated with pegylated interferon alpha-2a. Blood 2006; 108: 2037-2040.
    • (2006) Blood , vol.108 , pp. 2037-2040
    • Kiladjian, J.J.1    Cassinat, B.2    Turlure, P.3    Cambier, N.4    Roussel, M.5    Bellucci, S.6
  • 27
    • 0035878632 scopus 로고    scopus 로고
    • Soluble human leukocyte antigen-G serum level is elevated in melanoma patients and is further increased by interferon-alpha immunotherapy
    • Ugurel S, Rebmann V, Ferrone S, Tilgen W, Grosse-Wilde H, Reinhold U. Soluble human leukocyte antigen-G serum level is elevated in melanoma patients and is further increased by interferon-alpha immunotherapy. Cancer 2001; 92: 369-376.
    • (2001) Cancer , vol.92 , pp. 369-376
    • Ugurel, S.1    Rebmann, V.2    Ferrone, S.3    Tilgen, W.4    Grosse-Wilde, H.5    Reinhold, U.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.