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Volumn 180, Issue 3, 2008, Pages 1584-1591

A peptide that ameliorates lupus up-regulates the diminished expression of early growth response factors 2 and 3

Author keywords

[No Author keywords available]

Indexed keywords

CBL PROTEIN; DNA ANTIBODY; EARLY GROWTH RESPONSE FACTOR 2; EARLY GROWTH RESPONSE FACTOR 3; EDRATIDE; GAMMA INTERFERON; HUMAN MONOCLONAL ANTIBODY; INHIBITOR OF DIFFERENTIATION PROTEIN; INTERLEUKIN 1; MESSENGER RNA; PEPTIDE; PROTEIN KINASE B; RECOMBINANT INTERLEUKIN 2; SERYLLYSYLGLYCYLISOLEUCYLPROLYLGLUTAMINYLTYROSYLGLYCYLGLYCYLTRYPTOPHYL PROLYLTRYPTOPHYLGLUTAMYLTRYPTOPHYLARGINYLTHREONYLGLUTAMYLISOLEUCINE; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; INTERLEUKIN 2; MONOCLONAL ANTIBODY; PEPTIDE FRAGMENT; PHOSPHATIDYLINOSITOL 3 KINASE; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 40749118892     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.3.1584     Document Type: Article
Times cited : (24)

References (36)
  • 1
    • 0033119642 scopus 로고    scopus 로고
    • The EGR family of transcription-regulatory factors: Progress at the interface of molecular and systems neuroscience
    • O'Donovan, K. J., W. G. Tourtellote, J. Millbrandt, and J. M. Baraban. 1999. The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience. Trends Neurosci. 22: 167-173.
    • (1999) Trends Neurosci , vol.22 , pp. 167-173
    • O'Donovan, K.J.1    Tourtellote, W.G.2    Millbrandt, J.3    Baraban, J.M.4
  • 4
    • 4644285392 scopus 로고    scopus 로고
    • E3 ubiquitin ligases as T cell anergy factors
    • Mueller, D. L. 2004. E3 ubiquitin ligases as T cell anergy factors. Nat. Immunol. 5: 883-890.
    • (2004) Nat. Immunol , vol.5 , pp. 883-890
    • Mueller, D.L.1
  • 6
    • 0035221568 scopus 로고    scopus 로고
    • Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-γ but not TH2 cytokines
    • Kane, L. P., P. J. Andres, K. C. Howland, A. K. Abbas, and A. Weiss. 2001. Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-γ but not TH2 cytokines. Nat. Immunol. 2: 37-44.
    • (2001) Nat. Immunol , vol.2 , pp. 37-44
    • Kane, L.P.1    Andres, P.J.2    Howland, K.C.3    Abbas, A.K.4    Weiss, A.5
  • 9
    • 0038578823 scopus 로고    scopus 로고
    • The PI-3 kinase/Akt pathway and T cell activation: Pleiotropic pathways downstream of PIP3
    • Kane, L. P., and A. Weiss. 2003. The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3. Immunol. Rev. 192: 7-20.
    • (2003) Immunol. Rev , vol.192 , pp. 7-20
    • Kane, L.P.1    Weiss, A.2
  • 10
    • 0344585472 scopus 로고    scopus 로고
    • Increased severity of murine lupus in female mice is due to enhanced expansion of pathogenic T cells
    • Lang, T. J., P. Nguyen, J. C. Papadimitriou, and C. S. Via. 2003. Increased severity of murine lupus in female mice is due to enhanced expansion of pathogenic T cells. J. Immunol. 171: 5795-5801.
    • (2003) J. Immunol , vol.171 , pp. 5795-5801
    • Lang, T.J.1    Nguyen, P.2    Papadimitriou, J.C.3    Via, C.S.4
  • 11
    • 14244250736 scopus 로고    scopus 로고
    • Autoantibody explosion in systemic lupus erythematosus: More than 100 different antibodies found in SLE patients
    • Sherer, Y., A. Gorstein, M. J. Fritzler, and Y. Shoenfeld. 2004. Autoantibody explosion in systemic lupus erythematosus: more than 100 different antibodies found in SLE patients. Semin. Arthritis Rheum. 34: 501-537.
    • (2004) Semin. Arthritis Rheum , vol.34 , pp. 501-537
    • Sherer, Y.1    Gorstein, A.2    Fritzler, M.J.3    Shoenfeld, Y.4
  • 12
    • 2542551881 scopus 로고    scopus 로고
    • Identification of symmetrically expanded activated T cell clones in MRL/lpr and NZB/W F1 lupus model mice
    • Zhou, G., K. Fujio, A. Sadakata, A. Okamoto, R. Yu, and K. Yamamoto. 2004. Identification of symmetrically expanded activated T cell clones in MRL/lpr and NZB/W F1 lupus model mice. Clin. Exp. Immunol. 136: 448-455.
    • (2004) Clin. Exp. Immunol , vol.136 , pp. 448-455
    • Zhou, G.1    Fujio, K.2    Sadakata, A.3    Okamoto, A.4    Yu, R.5    Yamamoto, K.6
  • 13
    • 1942454327 scopus 로고    scopus 로고
    • Human lupus T cells resist inactivation and escape death by upregulating COX-2
    • Xu, L., L. Zhang, Y. Yi, H. K. Kang, and S. K. Datta. 2004. Human lupus T cells resist inactivation and escape death by upregulating COX-2. Nat. Med. 10: 411-415.
    • (2004) Nat. Med , vol.10 , pp. 411-415
    • Xu, L.1    Zhang, L.2    Yi, Y.3    Kang, H.K.4    Datta, S.K.5
  • 14
    • 0037388451 scopus 로고    scopus 로고
    • Pathogenic T cells in murine lupus exhibit spontaneous signaling activity through phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways
    • Niculescu, F., P. Nguyen, T. Niculescu, H. Rus, V. Rus, and C. S. Via. 2003. Pathogenic T cells in murine lupus exhibit spontaneous signaling activity through phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways. Arthritis Rheum. 48: 1071-1079.
    • (2003) Arthritis Rheum , vol.48 , pp. 1071-1079
    • Niculescu, F.1    Nguyen, P.2    Niculescu, T.3    Rus, H.4    Rus, V.5    Via, C.S.6
  • 18
    • 0027484975 scopus 로고
    • The role of the 16/6 idiotype network in the induction and manifestations of systemic lupus erythematosus
    • Waisman, A., S. Mendlovic, P. J. Ruiz, H. Zinger, A. Meshorer, and E. Mozes. 1993. The role of the 16/6 idiotype network in the induction and manifestations of systemic lupus erythematosus. Int. Immunol. 5: 1293-1300.
    • (1993) Int. Immunol , vol.5 , pp. 1293-1300
    • Waisman, A.1    Mendlovic, S.2    Ruiz, P.J.3    Zinger, H.4    Meshorer, A.5    Mozes, E.6
  • 19
    • 0030940121 scopus 로고    scopus 로고
    • Modulation of murine systemic lupus erythematosus with peptides based on complementarity determining regions of a pathogenic anti-DNA monoclonal antibody
    • Waisman, A., P. J. Ruiz, E. Israeli, E. Eilat, S. Konen-Waisman, H. Zinger, M. Dayan, and E. Mozes. 1997. Modulation of murine systemic lupus erythematosus with peptides based on complementarity determining regions of a pathogenic anti-DNA monoclonal antibody. Proc. Natl. Acad. Sci. USA 94: 4620-4625.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4620-4625
    • Waisman, A.1    Ruiz, P.J.2    Israeli, E.3    Eilat, E.4    Konen-Waisman, S.5    Zinger, H.6    Dayan, M.7    Mozes, E.8
  • 20
    • 0037328657 scopus 로고    scopus 로고
    • Peptides based on the complementarity-determining regions of a pathogenic autoantibody mitigate lupus manifestations of (NZB x NZW)F(1) mice via active suppression
    • Zinger, H., E. Eilat, A. Meshorer, and E. Mozes. 2003. Peptides based on the complementarity-determining regions of a pathogenic autoantibody mitigate lupus manifestations of (NZB x NZW)F(1) mice via active suppression. Int. Immunol. 15: 205-214.
    • (2003) Int. Immunol , vol.15 , pp. 205-214
    • Zinger, H.1    Eilat, E.2    Meshorer, A.3    Mozes, E.4
  • 21
    • 0035970048 scopus 로고    scopus 로고
    • The mechanism by which a peptide based on complementarity-determining region-1 of a pathogenic anti-DNA auto-Ab ameliorates experimental systemic lupus erythematosus
    • Eilat, E., M. Dayan, H. Zinger, and E. Mozes. 2001. The mechanism by which a peptide based on complementarity-determining region-1 of a pathogenic anti-DNA auto-Ab ameliorates experimental systemic lupus erythematosus. Proc. Natl. Acad. Sci. USA 98: 1148-1153.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1148-1153
    • Eilat, E.1    Dayan, M.2    Zinger, H.3    Mozes, E.4
  • 22
    • 0033863364 scopus 로고    scopus 로고
    • Prevention of systemic lupus erythematosus-like disease in (NZBxNZW)F1 mice by treating with CDR1- and CDR3-based peptides of a pathogenic autoantibody
    • Eilat, E., H. Zinger, A. Nyska, and E. Mozes. 2000. Prevention of systemic lupus erythematosus-like disease in (NZBxNZW)F1 mice by treating with CDR1- and CDR3-based peptides of a pathogenic autoantibody. J. Clin. Immunol. 20: 268-278.
    • (2000) J. Clin. Immunol , vol.20 , pp. 268-278
    • Eilat, E.1    Zinger, H.2    Nyska, A.3    Mozes, E.4
  • 23
    • 21644484449 scopus 로고    scopus 로고
    • A peptide based on the complementarity determining region 1 of a human monoclonal autoantibody ameliorates spontaneous and induced lupus manifestations in correlation with cytokine immunomodulation
    • Luger, D., M. Dayan, H. Zinger, J. P. Liu, and E. Mozes. 2004. A peptide based on the complementarity determining region 1 of a human monoclonal autoantibody ameliorates spontaneous and induced lupus manifestations in correlation with cytokine immunomodulation. J. Clin. Immunol. 24: 579-590.
    • (2004) J. Clin. Immunol , vol.24 , pp. 579-590
    • Luger, D.1    Dayan, M.2    Zinger, H.3    Liu, J.P.4    Mozes, E.5
  • 24
    • 10844263390 scopus 로고    scopus 로고
    • Downregulation of stromal cell-derived factor-1-α-induced T cell chemotaxis by a peptide based on the complementarity-determining region 1 of an anti-DNA autoantibody via up-regulation of TGFβ secretion
    • Sela, U., R. Hershkoviz, L. Cahalon, O. Lider, and E. Mozes. 2005. Downregulation of stromal cell-derived factor-1-α-induced T cell chemotaxis by a peptide based on the complementarity-determining region 1 of an anti-DNA autoantibody via up-regulation of TGFβ secretion. J. Immunol. 174: 302-309.
    • (2005) J. Immunol , vol.174 , pp. 302-309
    • Sela, U.1    Hershkoviz, R.2    Cahalon, L.3    Lider, O.4    Mozes, E.5
  • 25
    • 28244431801 scopus 로고    scopus 로고
    • The inhibition of autoreactive T cell functions by a peptide based on the CDR1 of an anti-DNA autoantibody is via TGF-mediated suppression of LFA-1 and CD44 expression and function
    • Sela, U., N. Mauermann, R. Hershkoviz, H. Zinger, M. Dayan, L. Cahalon, J. P. Liu, E. Mozes, and O. Lider. 2005. The inhibition of autoreactive T cell functions by a peptide based on the CDR1 of an anti-DNA autoantibody is via TGF-mediated suppression of LFA-1 and CD44 expression and function. J. Immunol. 175: 7255-7263.
    • (2005) J. Immunol , vol.175 , pp. 7255-7263
    • Sela, U.1    Mauermann, N.2    Hershkoviz, R.3    Zinger, H.4    Dayan, M.5    Cahalon, L.6    Liu, J.P.7    Mozes, E.8    Lider, O.9
  • 26
    • 33751206845 scopus 로고    scopus 로고
    • The negative regulators Foxj1 and Foxo3a are up-regulated by a peptide that inhibits systemic lupus erythematosus-associated T cell responses
    • Sela, U., M. Dayan, R. Hershkoviz, L. Cahalon, O. Lider, and E. Mozes. 2006. The negative regulators Foxj1 and Foxo3a are up-regulated by a peptide that inhibits systemic lupus erythematosus-associated T cell responses. Eur. J. Immunol. 36: 2971-2980.
    • (2006) Eur. J. Immunol , vol.36 , pp. 2971-2980
    • Sela, U.1    Dayan, M.2    Hershkoviz, R.3    Cahalon, L.4    Lider, O.5    Mozes, E.6
  • 27
    • 0032927145 scopus 로고    scopus 로고
    • Level of IL-12 in the sera of patients with systemic lupus erythematosus, rheumatoid arthritis, and other rheumatic diseases
    • Tokano, Y., S. Morimoto, H. Kaneko, H. Amanoo, K. Nozawa, Y. Takasaki, and H. Hashimoto. 1999. Level of IL-12 in the sera of patients with systemic lupus erythematosus, rheumatoid arthritis, and other rheumatic diseases. Clin. Exp. Immunol. 116: 169-173.
    • (1999) Clin. Exp. Immunol , vol.116 , pp. 169-173
    • Tokano, Y.1    Morimoto, S.2    Kaneko, H.3    Amanoo, H.4    Nozawa, K.5    Takasaki, Y.6    Hashimoto, H.7
  • 28
    • 0028939618 scopus 로고
    • The pathogenic human monoclonal anti-DNA that induces experimental systemic lupus erythematosus in mice is encoded by a VH4 gene segment
    • Waisman, A., Y. Shoenfeld, M. Blank, P. J. Ruiz, and E. Mozes. 1995. The pathogenic human monoclonal anti-DNA that induces experimental systemic lupus erythematosus in mice is encoded by a VH4 gene segment. Int. Immunol. 7: 689-696.
    • (1995) Int. Immunol , vol.7 , pp. 689-696
    • Waisman, A.1    Shoenfeld, Y.2    Blank, M.3    Ruiz, P.J.4    Mozes, E.5
  • 29
    • 0034658320 scopus 로고    scopus 로고
    • Protein kinase B regulates T lymphocyte survival, nuclear factor κB activation, and Bcl-X(L) levels in vivo
    • Jones, R. G., M. Parsons, M. Bonnard, V. S. Chan, W. C. Yeh, J. R. Woodgett, and P. S. Ohashi. 2000. Protein kinase B regulates T lymphocyte survival, nuclear factor κB activation, and Bcl-X(L) levels in vivo. J. Exp. Med. 191: 1721-1734.
    • (2000) J. Exp. Med , vol.191 , pp. 1721-1734
    • Jones, R.G.1    Parsons, M.2    Bonnard, M.3    Chan, V.S.4    Yeh, W.C.5    Woodgett, J.R.6    Ohashi, P.S.7
  • 31
    • 0036595050 scopus 로고    scopus 로고
    • T-cell signalling and autoimmunity: Molecular mechanisms of disease
    • Ohashi, P. S. 2002. T-cell signalling and autoimmunity: molecular mechanisms of disease. Nat. Rev. Immunol. 2: 427-438.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 427-438
    • Ohashi, P.S.1
  • 32
    • 0030953632 scopus 로고    scopus 로고
    • Roles of interferon-γ and interleukin-4 in murine Lupus
    • Peng, S. L., J. Moslehi, and J. Craft. 1997. Roles of interferon-γ and interleukin-4 in murine Lupus. J. Clin. Invest. 99: 1936-1946.
    • (1997) J. Clin. Invest , vol.99 , pp. 1936-1946
    • Peng, S.L.1    Moslehi, J.2    Craft, J.3
  • 34
    • 0028963222 scopus 로고
    • Experimental therapy for systemic lupus erythematosus: The treatment of NZB/W mice with mouse soluble interferon-γ receptor inhibits the onset of glomerulonephritis
    • Ozmen, L., D. Roman, M. Fountoulakis, G. Schmid, B. Ryffel, and G. Garotta. 1995. Experimental therapy for systemic lupus erythematosus: the treatment of NZB/W mice with mouse soluble interferon-γ receptor inhibits the onset of glomerulonephritis. Eur. J. Immunol. 25: 6-12.
    • (1995) Eur. J. Immunol , vol.25 , pp. 6-12
    • Ozmen, L.1    Roman, D.2    Fountoulakis, M.3    Schmid, G.4    Ryffel, B.5    Garotta, G.6
  • 35
    • 2342647439 scopus 로고    scopus 로고
    • PKB/Akt modulates TGF-β signalling through a direct interaction with Smad3
    • Remy, I., A. Montmarquette, and S. W. Michnick. 2004. PKB/Akt modulates TGF-β signalling through a direct interaction with Smad3. Nat. Cell. Biol. 6: 358-365.
    • (2004) Nat. Cell. Biol , vol.6 , pp. 358-365
    • Remy, I.1    Montmarquette, A.2    Michnick, S.W.3
  • 36
    • 2342471301 scopus 로고    scopus 로고
    • Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β induced apoptosis
    • Conery, A. R., Y. Cao, E. A. Thompson, C. M. Townsend, Jr., T. C. Ko, and K. Luo. 2004. Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β induced apoptosis. Nat. Cell. Biol. 6: 366-372.
    • (2004) Nat. Cell. Biol , vol.6 , pp. 366-372
    • Conery, A.R.1    Cao, Y.2    Thompson, E.A.3    Townsend Jr., C.M.4    Ko, T.C.5    Luo, K.6


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