Is dihydrolipoic acid among the reductive activators of parasite CysHis proteases?

Experimental Parasitology

Volumn 118, Issue 4, 2008, Pages 604-613

  Lockwood, Thomas D ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

Author keywords

Cathepsin B; DHLA; dihydrolipoic acid (reduced disulfhydryl); Falcipain 2; Iron redox; LA; LA(S S); lipoic acid (unspecified redox state); lipoic acid disulfide (oxidized disulfide); Malaria parasites; Plasmodium falciparum; Trypanosoma cruzi

Indexed keywords

CATHEPSIN B; DIHYDROLIPOATE; DISULFIDE; FALCIPAIN 2; FERRIC ION; FERROUS ION; GLUTATHIONE; PROTEINASE; SULFUR;

ADAPTATION; APICOPLAST; ARTICLE; DRUG RESISTANCE; HEMOLYSIS; NONHUMAN; OXIDATION REDUCTION REACTION; PHAGOCYTOSIS; PLASMODIUM; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; ANTIOXIDANTS; CATHEPSIN B; CYSTEINE; CYSTEINE ENDOPEPTIDASES; DITHIOTHREITOL; ENZYME ACTIVATION; ENZYME REACTIVATORS; GLUTATHIONE; HISTIDINE; IRON; MAMMALS; OXIDATION-REDUCTION; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; THIOCTIC ACID; TRYPANOSOMA CRUZI;

APICOMPLEXA; MAMMALIA; PLASMODIUM FALCIPARUM; TRYPANOSOMA CRUZI;

EID: 40649108075     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2007.11.001     Document Type: Article

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