IFN-α enhances poly-IC responses in human keratinocytes by inducing expression of cytosolic innate RNA receptors: Relevance for psoriasis

Journal of Investigative Dermatology

Volumn 128, Issue 4, 2008, Pages 932-938

  Prens, Errol P ^a   Kant, Marius ^a   Van Dijk, Grietje ^a   Van Der Wel, Leontine I ^a   Mourits, Sabine ^a   Van Der Fits, Leslie ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CYTOKINE; CYTOSOL RECEPTOR; DOUBLE STRANDED RNA; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5 PROTEIN; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN KINASE R; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INNATE IMMUNITY; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PSORIASIS; RECEPTOR UPREGULATION; SENSITIVITY ANALYSIS; SKIN DEFECT; SKIN INFLAMMATION;

EID: 40649087191     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5701087     Document Type: Article

References (36)

1. B.S. Baker J.M. Ovigne A.V. Powles S. Corcoran L. Fry Normal keratinocytes express Toll-like receptors (TLRs) 1, 2 and 5: modulation of TLR expression in chronic plaque psoriasis Br J Dermatol 148 2003 670 679
2. D. Bessis J.P. Moles N. Basset-Seguin A. Tesniere C. Arpin J.J. Guilhou Differential expression of a human endogenous retrovirus E transmembrane envelope glycoprotein in normal, psoriatic and atopic dermatitis human skin Br J Dermatol 151 2004 737 745
3. P. Boukamp R.T. Petrussevska D. Breitkreutz J. Hornung A. Markham N.E. Fusenig Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line J Cell Biol 106 1988 761 771
4. J.L. Curry J.Z. Qin B. Bonish R. Carrick P. Bacon J. Panella Innate immune-related receptors in normal and psoriatic skin Arch Pathol Lab Med 127 2003 178 186
5. R. Debets J.P. Hegmans R.J. Troost R. Benner E.P. Prens Enhanced production of biologically active interleukin-1 alpha and interleukin-1 beta by psoriatic epidermal cells ex vivo : evidence of increased cytosolic interleukin-1 beta levels and facilitated interleukin-1 release Eur J Immunol 25 1995 1624 1630
6. E. Erkek A. Karaduman Y. Akcan C. Sokmensuer G. Bukulmez Psoriasis associated with HCV and exacerbated by interferon alpha: complete clearance with acitretin during interferon alpha treatment for chronic active hepatitis Dermatology 201 2000 179 181
7. M. Favre G. Orth S. Majewski S. Baloul A. Pura S. Jablonska Psoriasis: a possible reservoir for human papillomavirus type 5, the virus associated with skin carcinomas of epidermodysplasia verruciformis J Invest Dermatol 110 1998 311 317
8. R.M. Grossman J. Krueger D. Yourish A. Granelli-Piperno D.P. Murphy L.T. May Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes Proc Natl Acad Sci USA 86 1989 6367 6371
9. V. Hornung J. Ellegast S. Kim K. Brzozka A. Jung H. Kato 5′-Triphosphate RNA is the ligand for RIG-I Science 314 2006 994 997
10. W.J. Kaiser J.L. Kaufman M.K. Offermann IFN-alpha sensitizes human umbilical vein endothelial cells to apoptosis induced by double-stranded RNA J Immunol 172 2004 1699 1710
11. H. Kato S. Sato M. Yoneyama M. Yamamoto S. Uematsu K. Matsui Cell type-specific involvement of RIG-I in antiviral response Immunity 23 2005 19 28
12. H. Kato O. Takeuchi S. Sato M. Yoneyama M. Yamamoto K. Matsui Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses Nature 441 2006 101 105
13. H. Kitamura Y. Matsuzaki K. Kimura H. Nakano T. Imaizumi K. Satoh Cytokine modulation of retinoic acid-inducible gene-I (RIG-I) expression in human epidermal keratinocytes J Dermatol Sci 45 2007 127 134
14. G. Kollisch B.N. Kalali V. Voelcker R. Wallich H. Behrendt J. Ring Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes Immunology 114 2005 531 541
15. M.C. Lebre A.M. van der Aar L. van Baarsen T.M. van Capel J.H. Schuitemaker M.L. Kapsenberg Human keratinocytes express functional Toll-like receptor 3, 4, 5, and 9 J Invest Dermatol 127 2007 331 341
16. S. Majewski M. Favre G. Orth S. Jablonska Is human papillomavirus type 5 the putative autoantigen involved in psoriasis? J Invest Dermatol 111 1998 541 542
17. M. Mempel V. Voelcker G. Kollisch C. Plank R. Rad M. Gerhard Toll-like receptor expression in human keratinocytes: nuclear factor kappaB controlled gene activation by Staphylococcus aureus is Toll-like receptor 2 but not Toll-like receptor 4 or platelet activating factor receptor dependent J Invest Dermatol 121 2003 1389 1396
18. E. Meylan J. Tschopp M. Karin Intracellular pattern recognition receptors in the host response Nature 442 2006 39 44
19. J.P. Moles A. Tesniere J.J. Guilhou A new endogenous retroviral sequence is expressed in skin of patients with psoriasis Br J Dermatol 153 2005 83 89
20. B. Nardelli L. Zaritskaya M. Semenuk Y.H. Cho D.W. LaFleur D. Shah Regulatory effect of IFN-kappa, a novel type I IFN, on cytokine production by cells of the innate immune system J Immunol 169 2002 4822 4830
21. F.O. Nestle C. Conrad A. Tun-Kyi B. Homey M. Gombert O. Boyman Plasmacytoid predendritic cells initiate psoriasis through interferon-{alpha} production J Exp Med 202 2005 135 143
22. A. Pichlmair O. Schulz C.P. Tan T.I. Naslund P. Liljestrom F. Weber RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates Science 314 2006 997 1001
23. A. Pivarcsi L. Bodai B. Rethi A. Kenderessy-Szabo A. Koreck M. Szell Expression and function of Toll-like receptors 2 and 4 in human keratinocytes Int Immunol 15 2003 721 730
24. E.P. Prens K. Benne T. van Joost R. Benner The autologous mixed epidermal cell-T lymphocyte reaction is elevated in psoriasis: a crucial role for epidermal HLA-DR+/CD1a- antigen-presenting cells J Invest Dermatol 96 1991 880 887
25. G. Prignano C. Ferraro A. Mussi F. Stivali E. Trento V. Bordignon Prevalence of human papilloma virus type 5 DNA in lesional and non-lesional skin scales of Italian plaque-type psoriatic patients: association with disease severity Clin Microbiol Infect 11 2005 47 51
26. P. Schmid P. Itin D. Cox G.K. McMaster M.A. Horisberger The type I interferon system is locally activated in psoriatic lesions J Interferon Res 14 1994 229 234
27. J. Siren J. Pirhonen I. Julkunen S. Matikainen IFN-{alpha} regulates TLR-dependent gene expression of IFN-{alpha}, IFN-{beta}, IL-28, and IL-29 J Immunol 174 2005 1932 1937
28. P.I. Song Y.M. Park T. Abraham B. Harten A. Zivony N. Neparidze Human keratinocytes express functional CD14 and toll-like receptor 4 J Invest Dermatol 119 2002 424 432
29. K. Taima T. Imaizumi K. Yamashita A. Ishikawa T. Fujita H. Yoshida Expression of IP-10/CXCL10 is upregulated by double-stranded RNA in BEAS-2B bronchial epithelial cells Respiration 73 2006 360 364
30. K. Takeda T. Kaisho S. Akira Toll-like receptors Annu Rev Immunol 21 2003 335 376
31. J. Tissari J. Siren S. Meri I. Julkunen S. Matikainen IFN-{alpha} enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression J Immunol 174 2005 4289 4294
32. M. Tohyama X. Dai K. Sayama K. Yamasaki Y. Shirakata Y. Hanakawa dsRNA-mediated innate immunity of epidermal keratinocytes Biochem Biophys Res Commun 335 2005 505 511
33. L. van der Fits L.I. van der Wel J.D. Laman E.P. Prens M.C. Verschuren Psoriatic lesional skin exhibits an aberrant expression pattern of interferon regulatory factor-2 (IRF-2) J Pathol 199 2003 107 114
34. L. van der Fits L.I. van der Wel J.D. Laman E.P. Prens M.C. Verschuren In psoriasis lesional skin the type I interferon signaling pathway is activated, whereas interferon-alpha sensitivity is unaltered J Invest Dermatol 122 2004 51 60
35. L. Visser H. Jan de Heer L.A. Boven D. van Riel M. van Meurs M.J. Melief Proinflammatory bacterial peptidoglycan as a cofactor for the development of central nervous system autoimmune disease J Immunol 174 2005 808 816
36. T. Yamamoto I. Katayama K. Nishioka Psoriasis and hepatitis C virus Acta Derm Venereol 75 1995 482 483