HIV secreted protein Tat prevents long-term potentiation in the hippocampal CA1 region

Brain Research

Volumn 1012, Issue 1-2, 2004, Pages 187-189

  Behnisch, Thomas ^a   Francesconi, Walter ^b,c   Sanna, Pietro Paolo ^c  

^a LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

^b UNIVERSITY OF PISA   (Italy)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Dementia; Disorders of the nervous system; HIV 1; Infectious diseases; Organotypic culture; Plasticity

Indexed keywords

TRANSACTIVATOR PROTEIN;

ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DEMENTIA; DISEASE ASSOCIATION; EXCITATORY POSTSYNAPTIC POTENTIAL; HIPPOCAMPUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NEUROLOGIC DISEASE; NEUROTOXICITY; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALS; EXCITATORY POSTSYNAPTIC POTENTIALS; GENE PRODUCTS, TAT; HIPPOCAMPUS; HIV; LONG-TERM POTENTIATION; MALE; ORGAN CULTURE TECHNIQUES; RATS; RATS, WISTAR;

EID: 2442432175     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.03.037     Document Type: Article

References (20)

1. Behnisch T., Reymann K.G. Co-activation of metabotropic glutamate and N-methyl-D-aspartate receptors is involved in mechanisms of long-term potentiation maintenance in rat hippocampal CA1 neurons. Neuroscience. 54:1993;37-47
2. Coan E.J., Irving A.J., Collingridge G.L. Low-frequency activation of the NMDA receptor system can prevent the induction of LTP. Neurosci. Lett. 105:1989;205-210
3. Colley P.A., Sheu F.S., Routtenberg A. Dose-dependent phorbol ester facilitation or blockade of hippocampal long-term potentiation: relation to membrane/cytosol distribution of protein kinase C activity. Brain Res. 495:1989;205-216
4. Ensoli B., Buonaguro L., Barillari G., Fiorelli V., Gendelman R., Morgan R.A., Wingfield P., Gallo R.C. Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J. Virol. 67:1993;277-287
5. Feligioni M., Raiteri L., Pattarini R., Grilli M., Bruzzone S., Cavazzani P., Raiteri M., Pittaluga A. The human immunodeficiency virus-1 protein Tat and its discrete fragments evoke selective release of acetylcholine from human and rat cerebrocortical terminals through species-specific mechanisms. J. Neurosci. 23:2003;6810-6818
6. Haughey N.J., Nath A., Mattson M.P., Slevin J.T., Geiger J.D. HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity. J. Neurochem. 78:2001;457-467
7. Krucker T., Toggas S.M., Mucke L., Siggins G.R. Transgenic mice with cerebral expression of human immunodeficiency virus type-1 coat protein gp120 show divergent changes in short- and long-term potentiation in CA1 hippocampus. Neuroscience. 83:1998;691-700
8. Kruman I.I., Nath A., Mattson M.P. HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress. Exp. Neurol. 154:1998;276-288
9. 2+]i homeostasis and induce neurotoxicity in human embryonic neurons. Eur. J. Neurosci. 7:1995;2285-2293
10. Leutgeb J.K., Frey J.U., Behnisch T. LTP in cultured hippocampal- entorhinal cortex slices from young adult (P25-30) rats. J. Neurosci. Methods. 130:2003;19-32
11. Lipton S.A., Brenneman D.E., Silverstein F.S., Masliah E., Mucke L. gp120 and neurotoxicity in vivo. Trends Pharmacol. Sci. 16:1995;122
12. Magnuson D.S., Knudsen B.E., Geiger J.D., Brownstone R.M., Nath A. Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity. Ann. Neurol. 37:1995;373-380
13. Nath A., Psooy K., Martin C., Knudsen B., Magnuson D.S., Haughey N., Geiger J.D. Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic. J. Virol. 70:1996;1475-1480
14. Ryan L.A., Cotter R.L., Zink W.E., Gendelman H.E., Zheng J. Macrophages, chemokines and neuronal injury in HIV-1-associated dementia. Cell. Mol. Biol. (Noisy-le-Grand). 48:2002;137-150
15. Sacktor N., Lyles R.H., Skolasky R., Kleeberger C., Selnes O.A., Miller E.N., Becker J.T., Cohen B., McArthur J.C. HIV-associated neurologic disease incidence changes: Multicenter AIDS Cohort Study, 1990-1998. Neurology. 56:2001;257-260
16. Sacktor N., McDermott M.P., Marder K., Schifitto G., Selnes O.A., McArthur J.C., Stern Y., Albert S., Palumbo D., Kieburtz K., De Marcaida J.A., Cohen B., Epstein L. HIV-associated cognitive impairment before and after the advent of combination therapy. J. Neurovirol. 8:2002;136-142
17. Sanchez-Alavez M., Criado J., Gomez-Chavarin M., Jimenez-Anguiano A., Navarro L., Diaz-Ruiz O., Galicia O., Sanchez-Narvaez F., Murillo-Rodriguez E., Henriksen S.J., Elder J.H., Prospero-Garcia O. HIV- and FIV-derived gp120 alter spatial memory, LTP, and sleep in rats. Neurobiol. Dis. 7:2000;384-394
18. Song L., Nath A., Geiger J.D., Moore A., Hochman S. Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site. J. Neurovirol. 9:2003;399-403
19. Xiang Z., Hrabetova S., Moskowitz S.I., Casaccia-Bonnefil P., Young S.R., Nimmrich V.C., Tiedge H., Einheber S., Karnup S., Bianchi R., Bergold P.J. Long-term maintenance of mature hippocampal slices in vitro. J. Neurosci. Methods. 98:2000;145-154
20. Xiong H., Zeng Y.C., Zheng J., Thylin M., Gendelman H.E. Soluble HIV-1 infected macrophage secretory products mediate blockade of long-term potentiation: a mechanism for cognitive dysfunction in HIV-1-associated dementia. J. Neurovirol. 5:1999;519-528