Structure of human MTH1, a nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates

Journal of Biological Chemistry

Volumn 279, Issue 32, 2004, Pages 33806-33815

  Mishima, Masaki ^a   Sakai, Yasunari ^b,c   Itoh, Noriyuki ^a   Kamiya, Hiroyuki ^d   Furuichi, Masato ^b,c   Takahashi, Masayuki ^e,f   Yamagata, Yuriko ^g   Iwai, Shigenori ^h   Nakabeppu, Yusaku ^b,c   Shirakawa, Masahiro ^i,j  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

^e INSTITUT CURIE   (France)

^f UNIVERSITÉ DE NANTES   (France)

^g KUMAMOTO UNIVERSITY   (Japan)

^h OSAKA UNIVERSITY   (Japan)

ⁱ YOKOHAMA CITY UNIVERSITY   (Japan)

^j RIKEN YOKOHAMA INSTITUTE   (Japan)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; DNA; PHOSPHATES; RESPIRATORY SYSTEM; SUBSTITUTION REACTIONS;

CHEMICAL SHIFTS; NUCLEOPHILIC SUBSTITUTION;

BIOCHEMISTRY;

2 HYDROXYDEOXYADENOSINE TRIPHOSPHATE; 8 OXODEOXYGUANOSINE TRIPHOSPHATE; ASPARAGINE; BACTERIAL PROTEIN; DEOXYADENOSINE TRIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; GENOMIC DNA; HYDROLASE; MITOCHONDRIAL DNA; MTH1 PROTEIN; NUCLEOSIDE DERIVATIVE; NUCLEOSIDE PHOSPHATE; NUCLEOSIDE TRIPHOSPHATE; OXYGEN RADICAL; PHOSPHATE; PROTEIN MUTT; PURINE NUCLEOSIDE; UNCLASSIFIED DRUG; WATER;

ARTICLE; BACTERIUM MUTANT; CELL RESPIRATION; CHEMICAL REACTION; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE MUTATION; HYDROLYSIS; MUTATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUDIX MOTIF; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ASPARAGINE; BINDING SITES; CONSERVED SEQUENCE; DEOXYGUANINE NUCLEOTIDES; DNA REPAIR ENZYMES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HUMANS; HYDROGEN BONDING; HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTATION; OXIDATION-REDUCTION; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PURINE NUCLEOTIDES; PYROPHOSPHATASES; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 4043174844     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402393200     Document Type: Article

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