메뉴 건너뛰기




Volumn 60, Issue 2, 2004, Pages 145-154

Flow cytometric analysis of isolated liver mitochondria to detect changes relevant to cell death

Author keywords

Cell death; Flow cytometry; Membrane potentials; Mitochondria; Mitochondrial permeability transition pore; Reactive oxygen species

Indexed keywords

1,1',3,3,3',3' HEXAMETHYLINDODICARBOCYANINE IODIDE; ACRIDINE ORANGE; CALCIUM; CARBOCYANINE; CELL PROTEIN; DICHLORODIHYDROFLUORESCEIN DIACETATE; FLUORESCENT DYE; REACTIVE OXYGEN METABOLITE; RHODAMINE; TETRAMETHYLRHODAMINE METHYL ESTER; UNCLASSIFIED DRUG;

EID: 4043066308     PISSN: 15524922     EISSN: None     Source Type: Journal    
DOI: 10.1002/cyto.a.20024     Document Type: Article
Times cited : (52)

References (48)
  • 1
    • 0033565557 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore and its role in cell death
    • Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochem J 1999;341(Pt 2):233-249.
    • (1999) Biochem J , vol.341 , Issue.PART 2 , pp. 233-249
    • Crompton, M.1
  • 2
    • 0031918742 scopus 로고    scopus 로고
    • The mitochondrial death/life regulator in apoptosis and necrosis
    • Kroemer G, Dallaporta B, Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 1998;60:619-642.
    • (1998) Annu Rev Physiol , vol.60 , pp. 619-642
    • Kroemer, G.1    Dallaporta, B.2    Resche-Rigon, M.3
  • 3
    • 0032504709 scopus 로고    scopus 로고
    • Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart
    • Halestrap AP, Kerr PM, Javadov S, Woodfield KY. Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. Biochim Biophys Acta 1998;1366:79-94.
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 79-94
    • Halestrap, A.P.1    Kerr, P.M.2    Javadov, S.3    Woodfield, K.Y.4
  • 7
    • 0037135559 scopus 로고    scopus 로고
    • No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria
    • Couplan E, del Mar Gonzalez-Barroso M, Alves-Guerra MC, Ricquier D, Goubern M, Bouillaud F. No evidence for a basal, retinoic, or superoxide-induced uncoupling activity of the uncoupling protein 2 present in spleen or lung mitochondria. J Biol Chem 2002;277:26268-26275.
    • (2002) J Biol Chem , vol.277 , pp. 26268-26275
    • Couplan, E.1    Del Mar Gonzalez-Barroso, M.2    Alves-Guerra, M.C.3    Ricquier, D.4    Goubern, M.5    Bouillaud, F.6
  • 8
    • 0027358554 scopus 로고
    • Changes in mitochondrial rhodamine-123-fluorescence populations of rat hepatocytes in primary culture
    • Hernandez-Berciano R, Garcia MV, Lopez-Mediavilla C, Orfao A, Medina JM. Changes in mitochondrial rhodamine-123-fluorescence populations of rat hepatocytes in primary culture. Exp Cell Res 1993;209:82-88.
    • (1993) Exp Cell Res , vol.209 , pp. 82-88
    • Hernandez-Berciano, R.1    Garcia, M.V.2    Lopez-Mediavilla, C.3    Orfao, A.4    Medina, J.M.5
  • 9
    • 0024299277 scopus 로고
    • Use of rhodamine 123 to investigate alterations in mitochondrial activity in isolated mouse liver mitochondria
    • O'Connor JE, Vargas JL, Kimler BF, Hernandez-Yago J, Grisolia S. Use of rhodamine 123 to investigate alterations in mitochondrial activity in isolated mouse liver mitochondria. Biochem Biophys Res Commun 1988;151:568-573.
    • (1988) Biochem Biophys Res Commun , vol.151 , pp. 568-573
    • O'Connor, J.E.1    Vargas, J.L.2    Kimler, B.F.3    Hernandez-Yago, J.4    Grisolia, S.5
  • 10
    • 84990553672 scopus 로고
    • Flow cytometric analysis of the effects of high protein diet on isolated rat liver mitochondria
    • O'Connor JE, Kimler BF, Vargas JL. Flow cytometric analysis of the effects of high protein diet on isolated rat liver mitochondria. Cell Tissue Kinet 1988;21:331-338.
    • (1988) Cell Tissue Kinet , vol.21 , pp. 331-338
    • O'Connor, J.E.1    Kimler, B.F.2    Vargas, J.L.3
  • 11
    • 0029143558 scopus 로고
    • Hypothyroidism prevents postnatal changes in rat liver mitochondrial populations defined by rhodamine-123 staining
    • Almeida A, Orfao A, Lopez-Mediavilla C, Medina JM. Hypothyroidism prevents postnatal changes in rat liver mitochondrial populations defined by rhodamine-123 staining. Endocrinology 1995;136:4448-4453.
    • (1995) Endocrinology , vol.136 , pp. 4448-4453
    • Almeida, A.1    Orfao, A.2    Lopez-Mediavilla, C.3    Medina, J.M.4
  • 12
    • 0028231236 scopus 로고
    • Postnatal changes in rhodamine-123 stained mitochondrial populations are sensitive to protein synthesis inhibitors but mimicked in vitro by ATP
    • Almeida A, Lopez-Mediavilla C, Orfao A, Medina JM. Postnatal changes in rhodamine-123 stained mitochondrial populations are sensitive to protein synthesis inhibitors but mimicked in vitro by ATP. FEBS Lett 1994;344:50-54.
    • (1994) FEBS Lett , vol.344 , pp. 50-54
    • Almeida, A.1    Lopez-Mediavilla, C.2    Orfao, A.3    Medina, J.M.4
  • 13
    • 0024418270 scopus 로고
    • Identification by flow cytometry of two distinct rhodamine-123-stained mitochondrial populations in rat liver
    • Lopez-Mediavilla C, Orfao A, Gonzalez M, Medina JM. Identification by flow cytometry of two distinct rhodamine-123-stained mitochondrial populations in rat liver. FEBS Lett 1989;254:115-120.
    • (1989) FEBS Lett , vol.254 , pp. 115-120
    • Lopez-Mediavilla, C.1    Orfao, A.2    Gonzalez, M.3    Medina, J.M.4
  • 14
    • 0026476212 scopus 로고
    • Developmental changes in rat liver mitochondrial populations analyzed by flow cytometry
    • Lopez-Mediavilla C, Orfao A, San Miguel J, Medina JM. Developmental changes in rat liver mitochondrial populations analyzed by flow cytometry. Exp Cell Res 1992;203:134-140.
    • (1992) Exp Cell Res , vol.203 , pp. 134-140
    • Lopez-Mediavilla, C.1    Orfao, A.2    San Miguel, J.3    Medina, J.M.4
  • 15
    • 0028799265 scopus 로고
    • Changes in adult rat liver mitochondrial populations at different energy states analyzed by flow cytometry
    • Lopez-Mediavilla C, Orfao A, Garcia MV, Medina JM. Changes in adult rat liver mitochondrial populations at different energy states analyzed by flow cytometry. Biochim Biophys Acta 1995;1232:27-32.
    • (1995) Biochim Biophys Acta , vol.1232 , pp. 27-32
    • Lopez-Mediavilla, C.1    Orfao, A.2    Garcia, M.V.3    Medina, J.M.4
  • 17
    • 0025690822 scopus 로고
    • Analysis of the membrane potential of rat- and mouse-liver mitochondria by flow cytometry and possible applications
    • Petit PX, O'Connor JE, Grunwald D, Brown SC. Analysis of the membrane potential of rat- and mouse-liver mitochondria by flow cytometry and possible applications. Eur J Biochem 1990;194:389-397.
    • (1990) Eur J Biochem , vol.194 , pp. 389-397
    • Petit, P.X.1    O'Connor, J.E.2    Grunwald, D.3    Brown, S.C.4
  • 18
    • 0032502866 scopus 로고    scopus 로고
    • Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: The impact of irreversible permeability transition
    • Petit PX, Goubern M, Diolez P, Susin SA, Zamzami N, Kroemer G. Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition. FEBS Lett 1998;426:111-116.
    • (1998) FEBS Lett , vol.426 , pp. 111-116
    • Petit, P.X.1    Goubern, M.2    Diolez, P.3    Susin, S.A.4    Zamzami, N.5    Kroemer, G.6
  • 20
    • 0030057708 scopus 로고    scopus 로고
    • Functional heterogeneity of an isolated mitochondrial population revealed by cyrofluorometric analysis at the single organelle level
    • Cossarizza A, Ceccarelli D, Masini A. Functional heterogeneity of an isolated mitochondrial population revealed by cyrofluorometric analysis at the single organelle level. Exp Cell Res 1996;222:84-94.
    • (1996) Exp Cell Res , vol.222 , pp. 84-94
    • Cossarizza, A.1    Ceccarelli, D.2    Masini, A.3
  • 22
    • 1842330849 scopus 로고    scopus 로고
    • Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione
    • Garcia-Ruiz C, Colell A, Mari M, Morales A, Fernandez-Checa JC. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J Biol Chem 1997;272:11369-11377.
    • (1997) J Biol Chem , vol.272 , pp. 11369-11377
    • Garcia-Ruiz, C.1    Colell, A.2    Mari, M.3    Morales, A.4    Fernandez-Checa, J.C.5
  • 25
    • 0032052217 scopus 로고    scopus 로고
    • Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes
    • Metivier D, Dallaporta B, Zamzami N, Larochette N, Susin SA, Marzo I, Kroemer G. Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes. Immunol Lett 1998;6:157-163.
    • (1998) Immunol Lett , vol.6 , pp. 157-163
    • Metivier, D.1    Dallaporta, B.2    Zamzami, N.3    Larochette, N.4    Susin, S.A.5    Marzo, I.6    Kroemer, G.7
  • 26
    • 0034075866 scopus 로고    scopus 로고
    • Localization of dichlorofluorescin in cardiac myocytes: Implications for assessment of oxidative stress
    • Swift LM, Sarvazyan N. Localization of dichlorofluorescin in cardiac myocytes: implications for assessment of oxidative stress. Am J Physiol Heart Circ Physiol 2000;278:H982-990.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Swift, L.M.1    Sarvazyan, N.2
  • 29
    • 0025471534 scopus 로고
    • Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation
    • Sims NR. Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation. J Neurochem 1990;55:698-707.
    • (1990) J Neurochem , vol.55 , pp. 698-707
    • Sims, N.R.1
  • 30
    • 0032528154 scopus 로고    scopus 로고
    • Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death
    • Friberg H, Ferrand-Drake M, Bengtsson F, Halestrap AP, Wieloch T. Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death. J Neurosci 1998;18:5151-5159.
    • (1998) J Neurosci , vol.18 , pp. 5151-5159
    • Friberg, H.1    Ferrand-Drake, M.2    Bengtsson, F.3    Halestrap, A.P.4    Wieloch, T.5
  • 31
    • 0033495895 scopus 로고    scopus 로고
    • Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion
    • Matsumoto S, Friberg H, Ferrand-Drake M, Wieloch T. Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion. J Cereb Blood Flow Metab 1999;19:736-741.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 736-741
    • Matsumoto, S.1    Friberg, H.2    Ferrand-Drake, M.3    Wieloch, T.4
  • 32
    • 0028230245 scopus 로고
    • Direct analysis and significance of cardiolipin transverse distribution in mitochondrial inner membranes
    • Petit JM, Huet O, Gallet PF, Maftah A, Ratinaud MH, Julien R. Direct analysis and significance of cardiolipin transverse distribution in mitochondrial inner membranes. Eur J Biochem 1994;220:871-879.
    • (1994) Eur J Biochem , vol.220 , pp. 871-879
    • Petit, J.M.1    Huet, O.2    Gallet, P.F.3    Maftah, A.4    Ratinaud, M.H.5    Julien, R.6
  • 33
    • 0033971898 scopus 로고    scopus 로고
    • Mitochondria and neuronal survival
    • Nicholls DG, Budd SL. Mitochondria and neuronal survival. Physiol Rev 2000;80:315-360.
    • (2000) Physiol Rev , vol.80 , pp. 315-360
    • Nicholls, D.G.1    Budd, S.L.2
  • 34
    • 0024483266 scopus 로고
    • Fluorescent labeling of mitochondria
    • Chen LB. Fluorescent labeling of mitochondria. Methods Cell Biol 1989;29:103-123.
    • (1989) Methods Cell Biol , vol.29 , pp. 103-123
    • Chen, L.B.1
  • 35
    • 0037116578 scopus 로고    scopus 로고
    • Flow cytometry of isolated mitochondria during development and under some pathological conditions
    • Medina JM, Lopez-Mediavilla C, Orfao A. Flow cytometry of isolated mitochondria during development and under some pathological conditions. FEBS Lett 2002;510:127-132.
    • (2002) FEBS Lett , vol.510 , pp. 127-132
    • Medina, J.M.1    Lopez-Mediavilla, C.2    Orfao, A.3
  • 36
    • 0141987911 scopus 로고    scopus 로고
    • Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation
    • Mattiasson G, Friberg H, Hansson M, Elmer E, Wieloch T. Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation. J Neurochem 2003;87:532-544.
    • (2003) J Neurochem , vol.87 , pp. 532-544
    • Mattiasson, G.1    Friberg, H.2    Hansson, M.3    Elmer, E.4    Wieloch, T.5
  • 37
    • 0034431166 scopus 로고    scopus 로고
    • Membrane potential estimation by flow cytometry
    • Shapiro HM. Membrane potential estimation by flow cytometry. Methods 2000:21:271-279.
    • (2000) Methods , vol.21 , pp. 271-279
    • Shapiro, H.M.1
  • 38
    • 0036068212 scopus 로고    scopus 로고
    • Intracellular distribution of the fluorescent dye nonyl acridine orange responds to the mitochondrial membrane potential: Implications for assays of cardiolipin and mitochondrial mass
    • Jacobson J, Duchen MR, Heales SJ. Intracellular distribution of the fluorescent dye nonyl acridine orange responds to the mitochondrial membrane potential: implications for assays of cardiolipin and mitochondrial mass. J Neurochem 2002;82:224-233.
    • (2002) J Neurochem , vol.82 , pp. 224-233
    • Jacobson, J.1    Duchen, M.R.2    Heales, S.J.3
  • 41
    • 0036670461 scopus 로고    scopus 로고
    • Membrane depolarization of isolated rat liver mitochondria attenuates permeability transition pore opening and oxidant production
    • Aronis A, Komarnitsky R, Shilo S, Tirosh O. Membrane depolarization of isolated rat liver mitochondria attenuates permeability transition pore opening and oxidant production. Antioxid Redox Signal 2002; 4:647-654.
    • (2002) Antioxid Redox Signal , vol.4 , pp. 647-654
    • Aronis, A.1    Komarnitsky, R.2    Shilo, S.3    Tirosh, O.4
  • 42
    • 0034740585 scopus 로고    scopus 로고
    • DeltaPsi(m)-dependent and -independent production of reactive oxygen species by rat brain mitochondria
    • Votyakova TV, Reynolds IJ. DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria. J Neurochem 2001;79:266-277.
    • (2001) J Neurochem , vol.79 , pp. 266-277
    • Votyakova, T.V.1    Reynolds, I.J.2
  • 43
    • 0025218905 scopus 로고
    • Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin
    • Rothe G, Valet G. Flow cytometric analysis of respiratory burst activity in phagocytes with hydroethidine and 2′,7′-dichlorofluorescin. J Leukoc Biol 1990;47:440-448.
    • (1990) J Leukoc Biol , vol.47 , pp. 440-448
    • Rothe, G.1    Valet, G.2
  • 44
    • 0030008052 scopus 로고    scopus 로고
    • Superoxide production in rat hippocampal neurons: Selective imaging with hydroethidine
    • Bindokas VP, Jordan J, Lee CC, Miller RJ. Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine. J Neurosci 1996;16:1324-1336.
    • (1996) J Neurosci , vol.16 , pp. 1324-1336
    • Bindokas, V.P.1    Jordan, J.2    Lee, C.C.3    Miller, R.J.4
  • 45
    • 0037449449 scopus 로고    scopus 로고
    • Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria
    • Hansson MJ, Persson T, Friberg H, Keep MF, Rees A, Wieloch T, Elmer E. Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria. Brain Res 2003;960:99-111.
    • (2003) Brain Res , vol.960 , pp. 99-111
    • Hansson, M.J.1    Persson, T.2    Friberg, H.3    Keep, M.F.4    Rees, A.5    Wieloch, T.6    Elmer, E.7
  • 46
    • 0033007651 scopus 로고    scopus 로고
    • Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability
    • Friberg H, Connern C, Halestrap AP, Wieloch T. Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability. J Neurochem 1999;72:2488-2497.
    • (1999) J Neurochem , vol.72 , pp. 2488-2497
    • Friberg, H.1    Connern, C.2    Halestrap, A.P.3    Wieloch, T.4
  • 47
    • 0019545593 scopus 로고
    • Measurement of mitochondrial volume independent of refractive index by light scattering
    • Mar T. Measurement of mitochondrial volume independent of refractive index by light scattering. J Biochem Biophys Methods 1981;4:177-184.
    • (1981) J Biochem Biophys Methods , vol.4 , pp. 177-184
    • Mar, T.1
  • 48
    • 0019878736 scopus 로고
    • The relationship between the size of mitochondria and the intensity of light that they scatter in different energetic states
    • Knight VA, Wiggins PM, Harvey JD, O'Brien JA. The relationship between the size of mitochondria and the intensity of light that they scatter in different energetic states. Biochim Biophys Acta 1981;637:146-151.
    • (1981) Biochim Biophys Acta , vol.637 , pp. 146-151
    • Knight, V.A.1    Wiggins, P.M.2    Harvey, J.D.3    O'Brien, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.