Nuclear localization properties of a conserved protuberance in the Sm core complex

Experimental Cell Research

Volumn 299, Issue 1, 2004, Pages 199-208

  Girard, Cyrille ^a   Mouaikel, John ^a   Neel, Henry ^a   Bertrand, Edouard ^a   Bordonné, Rémy ^a  

^a INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

Author keywords

Cajal body; NLS; Nuclear import; Sm proteins; SMN; snRNP biogenesis

Indexed keywords

CORE PROTEIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; MUTANT PROTEIN; PROTEIN SUBUNIT;

ALLELE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOPLASM; FLUORESCENCE; GENE CONSTRUCT; GENE DELETION; GENETIC CONSERVATION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOLOCALIZATION; MOLECULAR EVOLUTION; MOLECULAR MODEL; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION;

MAMMALIA;

EID: 4043055813     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.05.018     Document Type: Article

References (50)

1. Lührmann R., Kastner B., Bach M. Structure of spliceosomal snRNPs and their role in pre-mRNA splicing. Biochem. Biophys. Acta. 1087:1990;256-292
2. Hermann H., Fabrizio P., Raker V.A., Foulaki K., Hornig H., Brahms H., Lührmann R. snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions. EMBO J. 14:1995;2076-2088
3. Séraphin B. Sm and Sm-like proteins belong to a large family: identification of proteins of the U6 as well as the U1, U2, U4 and U5 snRNPs. EMBO J. 14:1995;2089-2098
4. Mattaj I.W. Cap trimethylation of U snRNA is cytoplasmic and dependent on U snRNP protein binding. Cell. 46:1986;905-911
5. Mattaj I.W. UsnRNP assembly and Transport. Birnstiel M.L. Structure and function of the major and minor small nuclear ribonucleoprotein particles. 1988;303-357 Springer Verlag, Berlin
6. Will C.L., Lührmann R. Spliceosomal UsnRNP biogenesis, structure and function. Curr. Opin. Cell Biol. 13:2001;290-301
7. Plessel G., Fischer U., Lührmann R. m3G cap hypermethylation of U1 small nuclear ribonucleoprotein (snRNP) in vitro: evidence that the U1 small nuclear RNA-(guanosine-N2)-methyltransferase is a non-snRNP cytoplasmic protein that requires a binding site on the Sm core domain. Mol. Cell. Biol. 14:1994;4160-4172
8. Fischer U., Lührmann R. An essential signaling role for the m3G cap in the transport of U1 snRNP to the nucleus. Science. 249:1990;786-790
9. Hamm J., Darzynkiewicz E., Tahara S.M., Mattaj I.W. The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal. Cell. 62:1990;569-577
10. Huber J., Cronshagen U., Kadokura M., Marshallsay C., Wada T., Sekine M., Lührmann R. Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure. EMBO J. 17:1998;4114-4126
11. Mouaikel J., Verheggen C., Bertrand E., Tazi J., Bordonné R. Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus. Mol. Cell. 9:2002;891-901
12. Mouaikel J., Narayanan U., Verheggen C., Matera A.G., Bertrand E., Tazi J., Bordonné R. Interaction between the small-nuclear-RNA cap hypermethylase and the spinal muscular atrophy protein, survival of motor neuron. EMBO Rep. 4:2003;616-622
13. Frugier T., Nicole S., Cifuentes-Diaz C., Melki J. The molecular bases of spinal muscular atrophy. Curr. Opin. Genet. Dev. 12:2002;294-298
14. Liu Q., Dreyfuss G. A novel nuclear structure containing the survival of motor neurons protein. EMBO J. 15:1996;3555-3565
15. Carvalho T., Almeida F., Calapez A., Lafarga M., Berciano M.T., Carmo-Fonseca M. The spinal muscular atrophy disease gene product, SMN: a link between snRNP biogenesis and the Cajal (coiled) body. J. Cell Biol. 147:1999;715-728
16. Paushkin S., Gubitz A.K., Massenet S., Dreyfuss G. The SMN complex, an assemblyosome of ribonucleoproteins. Curr. Opin. Cell Biol. 14:2002;305-312
17. Friesen W.J., Dreyfuss G. Specific sequences of the Sm and Sm-like (Lsm) proteins mediate their interaction with the spinal muscular atrophy disease gene product (SMN). J. Biol. Chem. 275:2000;26370-26375
18. Brahms H., Meheus L., de Brabandere V., Fischer U., Lührmann R. Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B' and the Sm-like protein LSm4, and their interaction with the SMN protein. RNA. 7:2001;1531-1542
19. Brahms H., Raymackers J., Union A., de Keyser F., Meheus L., Lührmann R. The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies. J. Biol. Chem. 275:2000;17122-17129
20. Friesen W.J., Massenet S., Paushkin S., Wyce A., Dreyfuss G. SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets. Mol. Cell. 7:2001;1111-1117
21. Friesen W.J., Paushkin S., Wyce A., Massenet S., Pesiridis G.S., Van Duyne G., Rappsilber J., Mann M., Dreyfuss G. The methylosome, a 20 S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins. Mol. Cell. Biol. 21:2001;8289-8300
22. Meister G., Eggert C., Bühler D., Brahms H., Kambach C., Fischer U. Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln. Curr. Biol. 11:2001;1990-1994
23. Bordonné R. Functional characterization of nuclear localization signals in yeast Sm proteins. Mol. Cell. Biol. 20:2000;7943-7954
24. Zhang D., Abovich N., Rosbash M. A biochemical function for the Sm complex. Mol. Cell. 7:2001;319-329
25. Gottschalk A., Tang J., Puig O., Salgado J., Neubauer G., Colot H.V., Mann M., Séraphin B., Rosbash M., Lührmann R., Fabrizio P. A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals five novel proteins. RNA. 4:1998;374-393
26. Lehmeier T., Raker V., Hermann H., Lührmann R. cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction. Proc. Natl. Acad. Sci. U. S. A. 91:1994;12317-12321
27. Rokeach L.A., Haselby J.A., Hoch S.O. Molecular cloning of a cDNA encoding the human Sm-D autoantigen. Proc. Natl. Acad. Sci. U. S. A. 85:1988;4832-4836
28. Rymond B.C. Convergent transcripts of the yeast PRP38-SMD1 locus encode two essential splicing factors, including the D1 core polypeptide of small nuclear ribonucleoprotein particles. Proc. Natl. Acad. Sci. U. S. A. 90:1993;848-852
29. van Dam A., Winkel I., Zijlstra-Baalbergen J., Smeenk R., Cuypers H.T. Cloned human snRNP proteins B and B' differ only in their carboxy-terminal part. EMBO J. 8:1989;3853-3860
30. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor
31. Niedenthal R.K., Riles L., Johnston M., Hegemann J.H. Green fluorescent protein as a marker for gene expression and subcellular localization in budding yeast. Yeast. 12:1996;773-786
32. Verheggen C., Lafontaine D.L., Samarsky D., Mouaikel J., Blanchard J.M., Bordonné R., Bertrand E. Mammalian and yeast U3 snoRNPs are matured in specific and related nuclear compartments. EMBO J. 21:2002;2736-2745
33. Dignam J.D., Lebovitz R.M., Roeder R.G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1983;1475-1489
34. Camasses A., Bragado-Nilsson E., Martin R., Séraphin B., Bordonné R. Interactions within the yeast Sm core complex: from proteins to amino acids. Mol. Cell. Biol. 18:1998;1956-1966
35. Mattaj I.W., Englmeier L. Nucleocytoplasmic transport: the soluble phase. Annu. Rev. Biochem. 67:1998;265-306
36. Matera A.G., Frey M.R. Coiled bodies and gems: janus or gemini? Am. J. Hum. Genet. 63:1998;317-321
37. Young P.J., Le T.T., thi Man N., Burghes A.H., Morris G.E. The relationship between SMN, the spinal muscular atrophy protein, and nuclear coiled bodies in differentiated tissues and cultured cells. Exp. Cell Res. 256:2000;365-374
38. Sleeman J.E., Lamond A.I. Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway. Curr. Biol. 19:1999;1065-1074
39. Sleeman J.E., Ajuh P., Lamond A.I. snRNP protein expression enhances the formation of Cajal bodies containing p80-coilin and SMN. J. Cell Sci. 114:2001;4407-4419
40. Kambach C., Walke S., Young R., Avis J.M., de la Fortelle E., Raker V.A., Lührmann R., Li J., Nagai K. Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. Cell. 96:1999;375-387
41. Stark H., Dube P., Lührmann R., Kastner B. Arrangement of RNA and proteins in the spliceosomal U1 small nuclear ribonucleoprotein particle. Nature. 409:2001;539-542
42. Liu Q., Fischer U., Wang F., Dreyfuss G. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell. 90:1997;1013-1021
43. Buhler D., Raker V., Luhrmann R., Fischer U. Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy. Hum. Mol. Genet. 8:1999;2351-2357
44. Jäkel S., Görlich D. Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells. EMBO J. 17:1998;4491-5402
45. Narayanan U., Ospina J.K., Frey M.R., Hebert M.D., Matera A.G. SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta. Hum. Mol. Genet. 11:2002;1785-1795
46. Palfi Z., Lucke S., Lahm H.W., Lane W.S., Kruft V., Bragado-Nilsson E., Séraphin B., Bindereif A. The spliceosomal snRNP core complex of Trypanosoma brucei: cloning and functional analysis reveals seven Sm protein constituents. Proc. Natl. Acad. Sci. U. S. A. 97:2000;8967-8972
47. Günzl A., Bindereif A., Ullu E., Tschudi C. Determinants for cap trimethylation of the U2 small nuclear RNA are not conserved between Trypanosoma brucei and higher eukaryotic organisms. Nucleic Acids Res. 28:2000;3702-3709
48. Hebert M.D., Shpargel K.B., Ospina J.K., Tucker K.E., Matera A.G. Coilin methylation regulates nuclear body formation. Dev. Cell. 3:2002;329-337
49. Boisvert F.M., Cote J., Boulanger M.C., Cleroux P., Bachand F., Autexier C., Richard S. Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing. J. Cell Biol. 159:2002;957-969
50. Sauterer R.A., Goyal A., Zieve G.W. Cytoplasmic assembly of small nuclear ribonucleoprotein particles from 6 S and 20 S RNA-free intermediates in L929 mouse fibroblasts. J. Biol. Chem. 265:1990;1048-1058