Effects of cysteine on the cytotoxicity of arsenic compounds

Archives of Environmental Contamination and Toxicology

Volumn 45, Issue 3, 2003, Pages 324-330

  Zhou, X ^a   Yoshida, K ^a   Kuroda, K ^a   Endo, Y ^b   Endo, G ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC ACID; ARSENIC DERIVATIVE; ARSENIC TRIOXIDE; CACODYLIC ACID; CYSTEINE; METHANEARSONIC ACID;

ARSENIC; ECOTOXICOLOGY;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IC 50; NICK END LABELING; PRIORITY JOURNAL; TOXICITY TESTING;

EID: 0141679340     PISSN: 00904341     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00244-002-0216-5     Document Type: Article

References (42)

1. Aposhian HV, Gurzau ES, Le XC, Gurzau A, Healy SM, Lu X, et al. (2000) Occurrence of monomethylarsonous acid in urine of humans exposed to inorganic arsenic. Chem Res Toxicol 13:693-697
2. 2 function: Amino acid and steroid derivatives. J Med Chem 22:572-575
3. Buchet JP, Lauwerys R, Roels H (1981) Comparison of the urinary-excretion of arsenic metabolites after a single oral dose of sodium arsenite, monomethylarsonate, or dimethylarsinate in man. Int Arch Occup Environ Health 48:71-79
4. Bursch W, Oberhammer F, Schulte-Hermann R (1992) Cell death by apoptosis and its protective role against disease. Trends Pharmacol Sci 13:245-251
5. Crouch SPM, Kozlowski R, Slater KJ, Fletcher J (1993) The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity. J Immunol Methods 160:81-88
6. Cullen WR, McBride BC, Reglinski J (1984a) The reaction of methylarsenicals with thiols: Some biological implications. J Inorg Biochem 21:179-194
7. Cullen WR, McBride BC, Reglinski J (1984b) The reduction of trimethylarsine oxide to trimethylarsine by thiols: A mechanistic model for the biological reduction of arsenicals. J Inorg Biochem 21:45-60
8. Delnomdedieu M, Basti MM, Otvos JD, Thomas DJ (1994) Reduction and binding of arsenate and dimethylarsinate by glutathione: A magnetic resonance study. Chem Biol Interact 90:139-155
9. Gong ZL, Lu XF, Cullen WR, Le XC (2001) Unstable trivalent arsenic metabolites, monomethylarsonous acid and dimethylarsinous acid. J Anal At Spectrom 16:1409-1413
10. IARC (1987) Monographs on the evaluation of the carcinogenic risks of chemicals to humans: Arsenic and arsenic compounds (group 1), supplement 7. International Agency for Research on Cancer (IARC) Lyon, pp 100-106
11. Irgolic KJ (1994) Determination of total arsenic and arsenic compounds in drinking water. In: Chappell WR, Abernathy CO, Cothern CR (eds) Arsenic: Exposure and health. Science and Technology Letters, Northwood, pp 51-60
12. Kaise T, Yamauchi H, Horiuchi Y, Tani T, Watanabe S, Hirayama T, Fukui S (1989) A comparative study on acute toxicity of methylarsonic acid, dimethylarsinic acid and trimethylarsine oxide in mice. Appl Organomet Chem 3:273-277
13. Kitamura M, Kuroda K, Endo Y, Endo G (2002) Cysteine enhances clastogenic activity of dimethylarsinic acid. Appl Organomet Chem 16:391-396
14. Le XC, Lu X, Ma M, Cullen WR, Aposhian HV, Zheng B (2000a) Speciation of key arsenic metabolic intermediates in human urine. Anal Chem 72:5172-5177
15. Le XC, Ma M, Cullen WR, Aposhian HV, Lu X, Zheng B (2000b) Determination of monomethylarsonous acid, a key arsenic methylation intremediate in human urine. Environ Health Perspect 108:1015-1018
16. Look AT (1998) Arsenic and apoptosis in the treatment of acute promyelocytic leukemia. J Natl Cancer Inst 90:86-88
17. Ma DC, Sun YH, Chang KZ, Ma XF, Huang SL, Bai YH, et al. (1998) Selective induction of apoptosis of NB4 cells from G2+M phase by sodium arsenite at lower doses. Eur J Haematol 61:27-35
18. Mandal BK, Ogra Y, Suzuki KT (2001) Identification of dimethylarsinous and monomethylarsonous acids in human urine of the arsenic-affected areas in West Bengal, India. Chem Res Toxicol 14:371-378
19. Marafante E, Vahter M, Norin H, Envall J, Sandstrom M, Christakopoulos A, Ryhage R (1987) Biotransformation of dimethylarsinic acid in mouse, hamster and man. J Appl Toxicol 7:111-117
20. Mass MJ, Tennant A, Roop BC, Cullen WR, Styblo M, Thomas DJ, Sandstrom M (2001) Methylated trivalent arsenic species are genotoxic. Chem Res Toxicol 14:355-361
21. NRC (1999) National Research Council report: Arsenic in the drinking water. National Academy Press, Washington, DC
22. Ochi T, Kaise T, Oya-Ohta Y (1994) Glutathione plays different roles in the induction of the cytotoxic effects of inorganic and organic arsenic compounds in cultured BALB/c 3T3 cells. Experientia 50:115-120
23. Ochi T, Nakajima F, Sakurai T, Kaise T, Oya-Ohta Y (1996) Dimethylarsinic acid causes apoptosis in HL-60 cells via interaction with glutathione. Arch Toxicol 70:815-821
24. III) is more toxic than arsenite in Chang human hepatocytes. Toxicol App Pharmacol 163:203-207
25. 50 in hamsters and in vitro inhibition of pyruvate dehydrogenase. Chem Res Toxicol 14:651-656
26. Pi J, Kumagai Y, Sun G, Yamauchi H, Yoshida T, Iso H, et al. (2000) Decreased serum concentrations of nitric oxide metabolites among Chinese in an endemic area of chronic arsenic poisoning in inner Mongolia. Free Radic Biol Med 28:1137-1142
27. Sakurai T, Kaise T, Matsubara C (1998) Inorganic and methylated arsenic compounds induce cell death in murine macrophages via different mechanisms. Chem Res Toxicol 11:273-283
28. Sakurai T, Qu W, Sakurai MH, Waalkes MP (2002) A major human arsenic metabolite, dimethylarsinic acid, requires reduced glutathione to induce apoptosis. Chem Res Toxicol 15:629-637
29. Scott N, Hatlelid KM, MacKenzie NE, Cater DE (1993) Reactions of arsenic(III) and arsenic(V) species with glutathione. Chem Res Toxicol 6:102-106
30. Styblo M, Del Razo LM, LeCluyse EL, Hamilton GA, Wang C, Cullen WR, Thomas DJ (1999) Metabolism of arsenic in primary cultures of human and rat hepatocytes. Chem Res Toxicol 12:560-565
31. Styblo M, Del Razo LM, Vega L, Germolec DR, LeCluyse EL, Hamilton GA, et al. (2000) Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells. Arch Toxicol 74:289-299
32. Thompson DJ (1993) A chemical hypothesis for arsenic methylation in mammals. Chem Biol Interact 88:89-114
33. Tornusciolo DRZ, Schmidt RE, Roth KA (1995) Simultaneous detection of TDT-mediated dUTP-biotin nick end-labeling (TUNEL)-positive cells and multiple immunohistochemical markers in single tissue sections. Bio Techniques 19:800-805
34. Vahter M (1994) Species differences in the metabolism of arsenic compounds. Appl Organomet Chem 8:175-182
35. Vahter M, Concha G, Nermell B (2000) Factors influencing arsenic methylation in humans. J Trace Elem Exp Med 13:173-184
36. Vahter M, Marafante E (1983) Intracellular interaction and metabolic fate of arsenite and arsenate in mice and rabbits. Chem Biol Interact 47:29-44
37. Vega L, Styblo M, Patterson R, Cullen WR, Wang C, Germolec D (2001) Differential effects of trivalent and pentavalent arsenicals on cell proliferation and cytokine secretion in normal human epidermal keratinocytes. Toxicol Appl Pharmacol 172:225-232
38. Waalkes MP, Fox DA, Christopher States J, Patierno SR, McCabe MJ Jr (2000) Metals and disorders of cell accumulation: modulation of apoptosis and cell proliferation. Toxicol Sci 56:255-261
39. Williams RH, Maggiore JA, Reynolds RD, Helgason CM (2001) Novel approach for the determination of the redox status of homocysteine and other aminothiols in plasma from healthy subjects and patients with ischemic stroke. Clin Chem 47:1031-1039
40. Yoshida K, Inoue Y, Kuroda K, Chen H, Wanibuchi H, Fukushima S, Endo G (1998) Urinary excretion of aesmic metabolites after long-term oral administration of various arsenic compounds to rats. J Toxicol Environ Health Part A 54:179-192
41. Zakharyan RA, Wu Y, Bogdan GM, Aposhian HV (1995) Enzymatic methylation of arsenic compounds. I. Assay, partial purification, and properties of arsenite methyltransferase and monomethylarsonic acid methyltransferase of rabbit liver. Chem Res Toxicol 8:1029-1038
42. Zeng H (2001) Arsenic suppresses necrosis induced by selenite in human leukemia HL-60 cells. Biol Trace Elem Res 83:1-15