The cough reflex in animals: Relevance to human cough research

Lung

Volumn 186, Issue SUPPL. 1, 2008, Pages

  Canning, Brendan J ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Bradykinin; Capsaicin; Nucleus of the solitary tract; Vagus

Indexed keywords

ANTITUSSIVE AGENT; CAPSAICIN; CITRIC ACID;

AEROSOL; BREATHING REFLEX; CONFERENCE PAPER; COUGHING; DISEASE MODEL; HUMAN; IN VITRO STUDY; INVASIVE PROCEDURE; MAMMAL; MEDICAL RESEARCH; NONHUMAN; PREDICTION; PRIORITY JOURNAL; SPECIES; STIMULUS;

ANIMALS; BIOMEDICAL RESEARCH; COUGH; DISEASE MODELS, ANIMAL; EXHALATION; HUMANS; INHALATION EXPOSURE; REFLEX;

EID: 40149089562     PISSN: 03412040     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00408-007-9054-6     Document Type: Conference Paper

References (59)

1. Horner J, Massey EW, Riski JE, Lathrop DL, Chase KN (1988) Aspiration following stroke: clinical correlates and outcome. Neurology 38(9):1359-1362
2. Nakagawa T, Sekizawa K, Arai H, Kikuchi R, Manabe K, Sasaki H (1997) High incidence of pneumonia in elderly patients with basal ganglia infarction. Arch Intern Med 157(3):321-324
3. Addington WR, Stephens RE, Gilliland KA (1999) Assessing the laryngeal cough reflex and the risk of developing pneumonia after stroke: an interhospital comparison. Stroke 30(6):1203-1207
4. Smith Hammond CA, Goldstein LB, Zajac DJ, Gray L, Davenport PW, Bolser DC (2001) Assessment of aspiration risk in stroke patients with quantification of voluntary cough. Neurology 56(4):502-506
5. Niimi A, Matsumoto H, Ueda T, Takemura M, Suzuki K, Tanaka E, Chin K, Mishima M, Amitani R (2003) Impaired cough reflex in patients with recurrent pneumonia. Thorax 58:152-153
6. Perrin C, Unterborn JN, Ambrosio CD, Hill NS (2004) Pulmonary complications of chronic neuromuscular diseases and their management. Muscle Nerve 29(1):5-27
7. Tatar M, Webber SE, Widdicombe JG (1988) Lung C-fibre receptor activation and defensive reflexes in anaesthetized cats. J Physiol 402:411-420
8. Kamei J, Iwamoto Y, Suzuki T, Misawa M, Nagase H, Kasuya Y (1993) Antitussive effects of naltrindole, a selective delta-opioid receptor antagonist, in mice and rats. Eur J Pharmacol 249(2):161-165
9. Tatar M, Sant'Ambrogio G, Sant'Ambrogio FB (1994) Laryngeal and tracheobronchial cough in anesthetized dogs. J Appl Physiol 76(6):2672-2679
10. Deep V, Singh M, Ravi K (2001) Role of vagal afferents in the reflex effects of capsaicin and lobeline in monkeys. Respir Physiol 125(3):155-168
11. Adcock JJ, Douglas GJ, Garabette M, Gascoigne M, Beatch G, Walker M, Page CP (2003) RSD931, a novel anti-tussive agent acting on airway sensory nerves. Br J Pharmacol 138(3):407-416
12. Bolser DC (2004) Experimental models and mechanisms of enhanced coughing. Pulm Pharmacol Ther 17(6):383-388
13. Lewis CA, Ambrose C, Banner K, Battram C, Butler K, Giddings J, Mok J, Nasra J, Winny C, Poll C (2007) Animal models of cough: literature review and presentation of a novel cigarette smoke-enhanced cough model in the guinea-pig. Pulm Pharmacol Ther 20(4):325-333
14. Karlsson JA, Fuller RW (1999) Pharmacological regulation of the cough reflex-from experimental models to antitussive effects in Man. Pulm Pharmacol Ther 12(4):215-228
15. Canning BJ, Mori N, Mazzone SB (2006) Vagal afferent nerves regulating the cough reflex. Respir Physiol Neurobiol 152(3):223-242
16. Canning BJ, Farmer DG, Mori N (2006) Mechanistic studies of acid-evoked coughing in anesthetized guinea pigs. Am J Physiol Regul Integr Comp Physiol 291(2):R454-R463
17. Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, Julius D (1998) The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21(3):531-543
18. Hayes P, Meadows HJ, Gunthorpe MJ, Harries MH, Duckworth DM, Cairns W, Harrison DC, Clarke CE, Ellington K, Prinjha RK, Barton AJ, Medhurst AD, Smith GD, Topp S, Murcodk P, Sanger GJ, Terrett J, Jenkins O, Benham CD, Randall AD, Gloger IS, Davis JB (2000) Cloning and functional expression of a human orthologue of rat vanilloid receptor-1. Pain 88(2):205-215
19. Savidge J, Davis C, Shah K, Colley S, Phillip E, Ranasinghe S, Winter J, Kotsonis P, Rang H, McIntyre P (2002) Cloning and functional characterization of the guinea pig vanilloid receptor 1. Neuropharmacology 43(3):450-456
20. Correll CC, Phelps PT, Anthes JC, Umland S, Greenfeder S (2004) Cloning and pharmacological characterization of mouse TRPV1. Neurosci Lett 370(1):55-60
21. Gavva NR, Klionsky L, Qu Y, Shi L, Tamir R, Edenson S, Zhang TJ, Viswanadhan VN, Toth A, Pearce LV, Vanderah TW, Porreca F, Blumberg PM, Lile J, Sun Y, Wild K, Louis JC, Treanor JJ (2004) Molecular determinants of vanilloid sensitivity in TRPV1. J Biol Chem 279(19):20283-20295
22. Bolser DC (1991) Fictive cough in the cat. J Appl Physiol 71(6):2325-2331
23. Ricco MM, Kummer W, Biglari B, Myers AC, Undem BJ (1996) Interganglionic segregation of distinct vagal afferent fibre phenotypes in guinea-pig airways. J Physiol 496(Pt 2):521-530
24. Undem BJ, Chuaychoo B, Lee MG, Weinreich D, Myers AC, Kollarik M (2004) Subtypes of vagal afferent C-fibres in guinea-pig lungs. J Physiol 556(Pt 3):905-917
25. Canning BJ, Mazzone SB, Meeker SN, Mori N, Reynolds SM, Undem BJ (2004) Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea-pigs. J Physiol 557(Pt 2):543-558
26. Mazzone SB, Mori N, Canning BJ (2005) Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs. J Physiol 569(Pt 2):559-573
27. Bonham AC, Chen CY, Sekizawa S, Joad JP (2006) Plasticity in the nucleus tractus solitarius and its influence on lung and airway reflexes. J Appl Physiol 101(1):322-327
28. Chuaychoo B, Lee MG, Kollarik M, Pullmann R Jr, Undem BJ (2006) Evidence for both adenosine A1 and A2A receptors activating single vagal sensory C-fibres in guinea pig lungs. J Physiol 575(Pt 2):481-490
29. Shannon R, Baekey DM, Morris KF, Li Z, Lindsey BG (2000) Functional connectivity among ventrolateral medullary respiratory neurones and responses during fictive cough in the cat. J Physiol 525(Pt 1):207-224
30. Bolser DC, Poliacek I, Jakus J, Fuller DD, Davenport PW (2006) Neurogenesis of cough, other airway defensive behaviors and breathing: A holarchical system? Respir Physiol Neurobiol 152(3):255-265
31. Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE, Brown KK, Canning BJ, Chang AB, Dicpinigaitis PV, Eccles R, Glomb WB, Goldstein LB, Graham LM, Hargreave FE, Kvale PA, Lewis SZ, McCool FD, McCrory DC, Prakash UB, Pratter MR, Rosen MJ, Schulman E, Shannon JJ, Smith Hammond C, Tarlo SM, American College of Chest Physicians (ACCP) (2006) Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest 129(1 Suppl):1S-23S
32. Morice AH, Fontana GA, Belvisi MG, Birring SS, Chung KF, Dicpinigaitis PV, Kastelik JA, McGarvey LP, Smith JA, Tatar M, Widdicombe J, European Respiratory Society (ERS) (2007) ERS guidelines on the assessment of cough. Eur Respir J 29(6):1256-1276
33. Ing AJ, Ngu MC, Breslin AB (1994) Pathogenesis of chronic persistent cough associated with gastroesophageal reflux. Am J Respir Crit Care Med 149(1):160-167
34. Wu DN, Yamauchi K, Kobayashi H, Tanifuji Y, Kato C, Suzuki K, Inoue H (2002) Effects of esophageal acid perfusion on cough responsiveness in patients with bronchial asthma. Chest 122(2):505-509
35. Kollarik M, Undem BJ (2002) Mechanisms of acid-induced activation of airway afferent nerve fibres in guinea-pig. J Physiol 543(Pt 2):591-600
36. Gu Q, Lee LY (2006) Characterization of acid signaling in rat vagal pulmonary sensory neurons. Am J Physiol Lung Cell Mol Physiol 291(1):L58-L65
37. Lalloo UG, Fox AJ, Belvisi MG, Chung KF, Barnes PJ (1995) Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs. J Appl Physiol 79(4):1082-1087
38. Trevisani M, Milan A, Gatti R, Zanasi A, Harrison S, Fontana G, Morice AH, Geppetti P (2004) Antitussive activity of iodo-resiniferatoxin in guinea pigs. Thorax 59(9):769-772
39. Mazzone SB, Canning BJ (2002) Central nervous system control of the airways: pharmacological implications. Curr Opin Pharmacol 2(3):220-228
40. Fox AJ, Lalloo UG, Belvisi MG, Bernareggi M, Chung KF, Barnes PJ (1996) Bradykinin-evoked sensitization of airway sensory nerves: a mechanism for ACE-inhibitor cough. Nat Med 2(7):814-817
41. Xiang A, Uchida Y, Nomura A, Iijima H, Dong F, Zhang MJ, Hasegawa S (1998) Effects of airway inflammation on cough response in the guinea pig. J Appl Physiol 85(5):1847-1854
42. Liu Q, Fujimura M, Tachibana H, Myou S, Kasahara K, Yasui M (2001) Characterization of increased cough sensitivity after antigen challenge in guinea pigs. Clin Exp Allergy 31(3):474-484
43. Xiang A, Uchida Y, Nomura A, Iijima H, Sakamoto T, Ishii Y, Morishima Y, Masuyama K, Zhang M, Hirano K, Sekizawa K (2002) Involvement of thromboxane A(2) in airway mucous cells in asthma-related cough. J Appl Physiol 92(2):763-770
44. House A, Celly C, Skeans S, Lamca J, Egan RW, Hey JA, Chapman RW (2004) Cough reflex in allergic dogs. Eur J Pharmacol 492(2-3):251-258
45. El-Hashim AZ, Amine SA (2005) The role of substance P and bradykinin in the cough reflex and bronchoconstriction in guinea-pigs. Eur J Pharmacol 513(1-2):125-133
46. Gatti R, Andre E, Amadesi S, Dinh TQ, Fischer A, Bunnett NW, Harrison S, Geppetti P, Trevisani M (2006) Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs. J Appl Physiol 101(2):506-511
47. Nishitsuji M, Fujimura M, Oribe Y, Nakao S (2007) Effect of montelukast in a guinea pig model of cough variant asthma. Pulm Pharmacol Ther (in press)
48. Fujimura M, Kamio Y, Kasahara K, Bando T, Hashimoto T, Matsuda T (1995) Prostanoids and cough response to capsaicin in asthma and chronic bronchitis. Eur Respir J 8(9):1499-1505
49. Dicpinigaitis PV, Dobkin JB, Reichel J (2002) Antitussive effect of the leukotriene receptor antagonist zafirlukast in subjects with cough-variant asthma. J Asthma 39(4):291-297
50. Spector SL, Tan RA (2004) Effectiveness of montelukast in the treatment of cough variant asthma. Ann Allergy Asthma Immunol 93(3):232-236
51. Oh EJ, Weinreich D (2004) Bradykinin decreases K(+) and increases Cl(-) conductances in vagal afferent neurones of the guinea pig. J Physiol 558(Pt 2):513-526
52. Lee MG, Macglashan DW Jr, Undem BJ (2005) Role of chloride channels in bradykinin-induced guinea pig airway vagal C-fibre activation. J Physiol 566(Pt 1):205-212
53. - channels regulate citric acid cough in guinea pigs. J Appl Physiol 101(2):635-643
54. Carr MJ (2006) Influence of mexiletine on action potential discharge and conduction in nodose Adelta afferent neurons innervating guinea pig isolated trachea. Pulm Pharmacol Ther 19(4):258-263
55. Canning BJ (2007) Encoding of the cough reflex. Pulm Pharmacol Ther 20(4):396-401
56. Bolser DC, Hey JA, Chapman RW (1999) Influence of central antitussive drugs on the cough motor pattern. J Appl Physiol 86(3):1017-1024
57. Joad JP, Munch PA, Bric JM, Evans SJ, Pinkerton KE, Chen CY, Bonham AC (2004) Passive smoke effects on cough and airways in young guinea pigs: role of brainstem substance P. Am J Respir Crit Care Med 169(4):499-504
58. Poliacek I, Corrie LW, Wang C, Rose MJ, Bolser DC (2007) Microinjection of DLH into the region of the caudal ventral respiratory column in the cat: evidence for an endogenous cough-suppressant mechanism. J Appl Physiol 102(3):1014-1021
59. Dicpinigaitis PV (2007) Experimentally induced cough. Pulm Pharmacol Ther 20(4):319-324