Antitussive effect of the leukotriene receptor antagonist zafirlukast in subjects with cough-variant asthma

Journal of Asthma

Volumn 39, Issue 4, 2002, Pages 291-297

  Dicpinigaitis, Peter V ^a   Dobkin, Jay B ^a   Reichel, Joseph ^a  

^a Albert Einstein Hospital   (United States)

Author keywords

Asthma; Capsaicin; Cough; Cough Variant asthma; Leukotriene receptor antagonists; Leukotrienes; Zafirlukast

Indexed keywords

BECLOMETASONE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; BUDESONIDE; CAPSAICIN; CORTICOSTEROID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIPHENHYDRAMINE; FLUTICASONE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LORATADINE; METHACHOLINE; ORCIPRENALINE; PSEUDOEPHEDRINE; SALBUTAMOL; SALMETEROL; TRIAMCINOLONE; ZAFIRLUKAST;

ADULT; ASTHMA; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DOUBLE BLIND PROCEDURE; DRUG MECHANISM; HUMAN; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY EPITHELIUM; TREATMENT FAILURE;

ADULT; ANTI-ASTHMATIC AGENTS; ASTHMA; BRONCHIAL PROVOCATION TESTS; CAPSAICIN; COUGH; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; LEUKOTRIENE ANTAGONISTS; MALE; MIDDLE AGED; TOSYL COMPOUNDS; TREATMENT OUTCOME;

EID: 0036094767     PISSN: 02770903     EISSN: None     Source Type: Journal    
DOI: 10.1081/JAS-120002285     Document Type: Conference Paper

References (19)

1. Chronic cough as the sole presenting manifestation of bronchial asthma
2. Cough-variant asthma: A review of the clinical literature
3. Interpretation of positive results of a methacholine inhalation challenge and 1 week of inhaled bronchodilator use in diagnosing and treating cough-variant asthma
4. Outcome of cough variant asthma treated with inhaled steroids
5. Malignant cough equivalent asthma: Definition and case reports
6. Neurophysiology of the cough reflex
7. The role of tachykinin receptor antagonists in the prevention of bronchial hyperresponsiveness, airway inflammation and cough
8. Treatment of asthma with drugs modifying the leukotriene pathway
9. Capsaicin-induced cough in humans
10. Product information
11. Cough reflex sensitivity in subjects with cervical spinal cord injury
12. Reproducibility and comparison of responses to inhaled histamine and methacholine
13. Reference values of the provocative concentrations of methacholine that cause 6% and 20% changes in forced expiratory volume in one second in a normal population
14. Effect of zafirlukast on cough reflex sensitivity in asthmatics
15. Efficacy of anti-LT agents in the treatment of chronic asthma
16. Cough-variant asthma successfully treated with a peptide leukotriene receptor antagonist
17. Effects of airway inflammation on cough response in the guinea pig
18. Summary of clinical trials with zafirlukast
19. Anti-inflammatory mechanisms of leukotriene modulators