The role of substance P and bradykinin in the cough reflex and bronchoconstriction in guinea-pigs

European Journal of Pharmacology

Volumn 513, Issue 1-2, 2005, Pages 125-133

  El Hashim, Ahmed Z ^a   Amine, Sanaa A ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Bradykinin; Citric acid and cough; Substance P

Indexed keywords

BRADYKININ; CITRIC ACID; DIPROTIN A; ENKEPHALINASE INHIBITOR; IRRITANT AGENT; PHOSPHORAMIDON; SUBSTANCE P;

AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREATHING REFLEX; BRONCHOSPASM; CONTROLLED STUDY; COUGHING; EXAMINATION; EXPOSURE; GUINEA PIG; MALE; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST;

ANIMALS; BRADYKININ; BRONCHOCONSTRICTION; CITRIC ACID; COUGH; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCOPEPTIDES; GUINEA PIGS; MALE; OLIGOPEPTIDES; PROTEASE INHIBITORS; REFLEX; SUBSTANCE P; TIME FACTORS;

EID: 18844462728     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.02.007     Document Type: Article

References (54)

1. J.J. Adcock Mechanism of cough S. Domenico Drugs for the treatment of respiratory diseases 2003 Cambridge University Press Cambridge, UK 553 564
2. P. Andersson, O.A. Olsson, and B. Waldeck Some problems encountered in the evaluation of new bronchodilating beta-adrenoceptor agonists Acta Pharm. Toxicol. 51 1982 358 364
3. P.J. Barnes Bradykinin and asthma Thorax 47 1992 979 983
4. C.R. Baumgarten, A. Witzel, J. Kleine-Tebbe, and G. Kunkel Substance P enhances antigen-evoked mediator release from human nasal mucosa Peptides 17 1996 25 30
5. E. Boichot, K. Biyah, N. Germain, X. Emonds-Alt, V. Lagente, and C. Advenier Involvement of tachykinin NK1 and NK2 receptors in substance P-induced microvascular leakage hypersensitivity and airway hyperresponsiveness in guinea-pigs Eur. Respir. J. 9 1996 1445 1450
6. D.C. Bolser, F.C. Degennaro, S. O'reilly, R.L. Mcleod, and J.A. Hey Central antitussive activity of the NK1 and NK2 tachykinin receptor antagonists, CP-99,994 and SR 48968, in the guinea-pig and cat Br. J. Pharmacol. 121 1997 165 170
7. A.C. Bonham, K.S. Kott, K. Ravi, C.T. Kappagoda, and J.P. Joad Substance P contributes to rapidly adapting receptor responses to pulmonary venous congestion in rabbits J. Physiol. 493 Pt 1 1996 229 238
8. B.J. Canning Interactions between vagal afferent nerve subtypes mediating cough Pulm. Pharmacol. Ther. 15 2002 187 192
9. M.J. Carr, M. Kollarik, S.N. Meeker, and B.J. Undem A role for TRPV1 in bradykinin-induced excitation of vagal airway afferent nerve terminals J. Pharmacol. Exp. Ther. 304 2003 1275 1279
10. D. Cheung, H. van der Veen, J. den Hartigh, J.H. Dijkman, and P.J. Sterk Effects of inhaled substance P on airway responsiveness to methacholine in asthmatic subjects in vivo J. Appl. Physiol. 77 1994 1325 1332
11. B.T. Chong, D.K. Agrawal, F.A. Romero, and R.G. Townley Measurement of bronchoconstriction using whole-body plethysmograph: comparison of freely moving versus restrained guinea pigs J. Pharmacol. Toxicol Methods 39 1998 163 168
12. G.N. Colasurdo, J.E. Loader, J.P. Graves, and G.L. Larsen Modulation of acetylcholine release in rabbit airways in vitro Am. J. Physiol. 268 1995 L432 L437
13. M.R. Corboz, X. Fernandez, C.A. Rizzo, S. Tozzi, M.E. Monahan, and J.A. Hey Increased blocking activity of combined tachykinin NK1- and NK2-receptor antagonists on tachykinergic bronchomotor responses in the guinea-pig Auton. Autacoid Pharmacol. 23 2003 79 93
14. N. Crimi, F. Palermo, R. Oliveri, B. Palermo, C. Vancheri, R. Polosa, and A. Mistretta Influence of antihistamine (astemizole) and anticholinergic drugs (ipratropium bromide) on bronchoconstriction induced by substance P Ann. Allergy 65 1990 115 120
15. S. Daoui, Y.Y. Cui, V. Lagente, X. Emonds-Alt, and C. Advenier A tachykinin NK3 receptor antagonist, SR 142801 (osanetant), prevents substance P-induced bronchial hyperreactivity in guinea-pigs Pulm. Pharmacol. Ther. 10 1997 261 270
16. B.J. Davis, and H.M. Smith Neurokinin-1 receptor immunoreactivity in the nucleus of the solitary tract in the hamster NeuroReport 10 1999 1003 1006
17. A.Z. El-Hashim, D. Wyss, K. Hoshiko, and C.A. Lewis Effects of DNK333A, a dual neurokinin NK1/NK2 receptor antagonist citric acid induced bronchoconstrictionand capsaicin-induced extravasation in guinea pigs Am. J. Respir. Crit. Care Med. 153 2001 A629
18. A.Z. El-Hashim, D. Wyss, and C. Lewis Effect of a novel NK1 receptor selective antagonist (NKP608) on citric acid induced cough and airway obstruction Pulm. Pharmacol. Ther. 17 2004 11 18
19. A.J. Fox, M. Bernareggi, U.G. Lalloo, K.F. Chung, P.J. Barnes, and M.G. Belvisi The effect of substance P on the cough reflex and airway sensory nerves in guinea-pigs Am. J. Respir. Crit. Care Med. 153 1996 A162
20. A.J. Fox, U.G. Lalloo, M.G. Belvisi, M. Bernareggi, K.F. Chung, and P.J. Barnes Bradykinin-evoked sensitization of airway sensory nerves: a mechanism for ACE-inhibitor cough Nat. Med. 2 1996 814 817
21. E. Hamelmann, J. Schwarze, K. Takeda, A. Oshiba, G.L. Larsen, C.G. Irvin, and E.W. Gelfand Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography Am. J. Respir. Crit. Care Med. 156 1997 766 775
22. M. Hargreaves, K. Ravi, M.P. Senaratne, and C.T. Kappagoda Responses of airway rapidly adapting receptors to bradykinin before and after administration of enalapril in rabbits Clin. Sci. (Lond.) 83 4 1992 399 407
23. M. Hargreaves, K. Ravi, and C.T. Kappagoda Effect of bradykinin on respiratory rate in anaesthetized rabbits; role of rapidly adapting receptors J. Physiol. 468 1993 501 513
24. C.J. Helke, D.M. Jacobowitz, and N.B. Thoa Capsaicin and potassium evoked substance P release from the nucleus tractus solitarius and spinal trigeminal nucleus in vitro Life Sci. 29 1981 1779 1785
25. X.Y. Hua, S.M. Back, and E.K. Tam Substance P enhances electrical field stimulation-induced mast cell degranulation in rat trachea Am. J. Physiol. 270 1996 L985 L991
26. G. Joos, R. Pauwels, and M. van der Straeten Effect of inhaled substance P and neurokinin A on the airways of normal and asthmatic subjects Thorax 42 1987 779 783
27. G.F. Joos, P.R. Germonpre, and R.A. Pauwels Role of tachykinins in asthma Allergy 55 2000 321 337
28. B.L. Koch, A.A. Edvinsson, and L.O. Koskinen Inhalation of substance P and thiorphan: acute toxicity and effects on respiration in conscious guinea pigs J. Appl. Toxicol. 19 1999 19 23
29. H. Kohrogi, P.D. Graf, K. Sekizawa, D.B. Borson, and J.A. Nadel Neutral endopeptidase inhibitors potentiate substance P and capsaicin induced cough in awake guinea-pigs J. Clin. Invest. 82 1988 2063 2068
30. M. Kollarik, and B.J. Undem Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice J. Physiol. 15;555 Pt 1 2004 115 123
31. T. Kondo, I. Kobayashi, N. Hayama, and Y. Ohta An increase in the threshold of citric acid-induced cough during chest wall vibration in healthy humans Jpn. J. Physiol. 48 1998 341 345
32. U.G. Lalloo, A.J. Fox, M.G. Belvisi, K.F. Chung, and P.J. Barnes Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea-pigs J. Appl. Physiol. 79 1995 1082 1087
33. J.M. Lundberg, C.R. Martling, and A. Saria Substance P and capsaicin-induced contraction of human bronchi Acta Physiol. Scand. 119 1983 49 53
34. M.A. Martins, S.A. Shore, and J.M. Drazen Capsaicin-induced release of tachykinins: effects of enzyme inhibitors J. Appl. Physiol. 7 1991 1950 1956
35. M.A. Martins, S.A. Shore, and J.M. Drazen Release of tachykinins by histamine, methacholine, PAF, LTD4, and substance P from guinea pig lungs Am. J. Physiol. 261 1991 L449 L455
36. S. Matsumoto, M. Yamasaki, T. Kanno, T. Nagayama, M. Tanno, and T. Shimizu Substance P antagonist does not block the stimulation of rapidly adapting pulmonary stretch receptors by ammonia Lung 172 1 1994 31 45
37. S.B. Mazzone, and B.J. Canning Synergistic interactions between airway afferent nerve subtypes mediating reflex bronchospasm in guinea pigs Am. J. Physiol., Regul. Integr. Comp. Physiol. 283 2002 R86 R98
38. B. Moreaux, A. Nemmar, G. Vincke, D. Halloy, D. Beerens, C. Advenier, and P. Gustin Role of substance P and tachykinin receptor antagonists in citric acid-induced cough in pigs Eur. J. Pharmacol. 408 2000 305 312
39. B. Moreaux, C. Advenier, and P. Gustin Role of bradykinin and tachykinins in the potentiation by enalapril of coughing induced by citric acid in pigs Fundam. Clin. Pharmacol. 15 2001 23 29
40. N.R. Prabhakar, M. Runold, Y. Yamamoto, H. Lagercrantz, N.S. Cherniack, and C. Von Euler Role of the vagal afferents in substance P-induced respiratory responses in anaesthetized rabbits Acta Physiol. Scand. 131 1 1987 63 71
41. D. Regoli, M.A. Boudon, and J.L. Fauchere Receptors and antagonists for substance P and related peptides Pharmacol. Rev. 46 1994 551 599
42. K. Sekizawa, T. Ebihara, and H. Sasaki Role of substance P in cough during bronchoconstriction in awake guinea-pigs Am. J. Respir. Crit. Care Med. 151 1995 815 821
43. S.A. Shore, N.P. Stimler-Gerard, S.R. Coats, and J.M. Drazen Substance P-induced bronchoconstriction in the guinea pig. Enhancement by inhibitors of neutral metalloendopeptidase and angiotensin-converting enzyme Am. Rev. Respir. Dis. 137 1988 331 336
44. D.H. Smith Treatment of hypertension with an angiotensin II-receptor antagonist compared with an angiotensin-converting enzyme inhibitor: a review of clinical studies of telmisartan and enalapril Clin. Ther. 2002 241484 241501
45. K. Takahama, J. Fuchikami, Y. Isohama, H. Kai, and T. Miyata Neurokinin A, but not neurokinin B and substance P, induces codeine-resistant coughs in awake guinea-pigs Regul. Pept. 46 1993 236 237
46. K. Takahama, J. Fuchikami, H. Kai, Y. Isohama, and T. Miyata Inhalation of phosphoramidon, a neutral endopeptidase inhibitor, induces cough in awake guinea-pigs Arch. Int. Pharmacodyn. Ther. 330 1995 241 250
47. A. Trifilieff, A. Da Silva, and J.P. Gies Kinins and respiratory tract diseases Eur. Respir. J. 6 1993 576 587
48. A. Trifilieff, A. El-Hashim, and C. Bertrand Time course of inflammatory and remodeling events in a murine model of asthma: effect of steroid treatment Am. J. Physiol., Lung Cell. Mol. Physiol. 279 2000 L1120 L1128
49. A. Trifilieff, A. El-Hasim, R. Corteling, and C.E. Owen Abrogation of lung inflammation in sensitized Stat6-deficient mice is dependent on the allergen inhalation procedure Br. J. Pharmacol. 130 2000 1581 1588
50. Y. Ujiie, K. Sekizawa, T. Aikawa, and H. Sasaki Evidence for substance P as an endogenous substance causing cough in guinea-pigs Am. Rev. Respir. Dir. 148 1993 1628 1632
51. B.J. Undem, and M.J. Carr Pharmacology of airway afferent nerve activity Respir. Res. 2 2001 234 244
52. B.J. Undem, M.J. Carr, and M. Kollarik Physiology and plasticity of putative cough fibres in the Guinea pig Pulm. Pharmacol. Ther. 15 2002 193 198
53. A. Xiang, Y. Uchida, A. Nomura, H. Iijima, F. Dong, M.J. Zhang, and S. Hasegawa Effects of airway inflammation on cough response in the guinea pig J. Appl. Physiol. 85 1998 1847 1854
54. R. Yasumitsu, Y. Hirayama, T. Imai, K. Miyayasu, and J. Hiroi Effects of specific tachykinin receptor antagonist on citric acid induced cough and bronchoconstriction in unanesthetized guinea pig Eur. J. Pharmacol. 300 1996 215 219