Temperature-Dependent, Irreversible Formation of Amyloid Fibrils by a Soluble Human Ataxin-3 Carrying a Moderately Expanded Polyglutamine Stretch (Q36)

Biochemistry

Volumn 42, Issue 49, 2003, Pages 14626-14632

  Shehi, Erlet ^a   Fusi, Paola ^a   Secundo, Francesco ^b   Pozzuolo, Sabrina ^a   Bairati, Aurelio ^c   Tortora, Paolo ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; DISEASES; ELECTRON MICROSCOPY; HEAT RESISTANCE; NEUROLOGY; PRECIPITATION (CHEMICAL);

ANTIAMYLOIDOGENIC COMPOUNDS;

PROTEINS;

AMYLOID; ATAXIN 3; POLYGLUTAMINE; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BETA SHEET; CIRCULAR DICHROISM; ELECTRON MICROSCOPY; HEAT TOLERANCE; HEAT TREATMENT; HUMAN; MACHADO JOSEPH DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRECIPITATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; ROOM TEMPERATURE; SPINOCEREBELLAR DEGENERATION; STRUCTURE ANALYSIS; TEMPERATURE DEPENDENCE; THERMOSTABILITY;

AMYLOID; ANIMALS; CIRCULAR DICHROISM; COLORING AGENTS; CONGO RED; ENDOPEPTIDASES; GLUTAMINE; GLUTATHIONE TRANSFERASE; HEAT; HUMANS; HYDROLYSIS; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDES; PRECIPITATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; SOLUBILITY; SPECTROPHOTOMETRY; TEMPERATURE; TRANSCRIPTION FACTORS;

MURINAE; STAPHYLOCOCCUS PHAGE 3A;

EID: 0347481134     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0352825     Document Type: Article

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