Polyglutamine aggregation nucleation: Thermodynamics of a highly unfavorable protein folding reaction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 43, 2005, Pages 15400-15405

  Bhattacharyya, Anusri M ^a,b   Thakur, Ashwani K ^a   Wetzel, Ronald ^a  

^a UNIVERSITY OF TENNESSEE GRADUATE SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Amyloid; Huntington's disease; Nucleated growth polymerization; Nucleation free energy

Indexed keywords

POLYGLUTAMINE;

ARTICLE; CHEMICAL REACTION KINETICS; DISEASE COURSE; ENERGY TRANSFER; EQUILIBRIUM CONSTANT; HUMAN; HUNTINGTON CHOREA; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN FOLDING; THERMODYNAMICS;

AMYLOID; PEPTIDES; PROTEIN FOLDING; THERMODYNAMICS;

EID: 27344435254     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0501651102     Document Type: Article

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