The virion-associated incoming HIV-I RNA genome is not targeted by RNA interference

Retrovirology

Volumn 3, Issue , 2006, Pages

  Westerhout, Ellen M ^a   ter Brake, Olivier ^a   Berkhout, Ben ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; NEF PROTEIN; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; VIRUS RNA;

ARTICLE; CELL LINE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; PROVIRUS; REVERSE TRANSCRIPTION; RNA INTERFERENCE; SEQUENCE ANALYSIS; VESICULAR STOMATITIS VIRUS; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRION; VIRUS ENVELOPE; VIRUS GENOME; VIRUS PARTICLE; VIRUS REPLICATION;

CLONING, MOLECULAR; GENE PRODUCTS, NEF; GENETIC THERAPY; GENETIC VECTORS; GENOME, VIRAL; GREEN FLUORESCENT PROTEINS; HIV INFECTIONS; HIV-1; HUMANS; LENTIVIRUS; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; RNA INTERFERENCE; RNA, SMALL INTERFERING; RNA, VIRAL; T-LYMPHOCYTES; TRANSDUCTION, GENETIC; VIRION;

HUMAN IMMUNODEFICIENCY VIRUS 1; VESICULAR STOMATITIS VIRUS;

EID: 33748978456     PISSN: 17424690     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-3-57     Document Type: Article

References (41)

1. Hammond SM, Bernstein E, Beach D, Hannon GJ: An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 2000, 404:293-296.
2. Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391:806-811.
3. Elbashir SM, Lendeckel W, Tuschl T: RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 2001, 15:188-200.
4. Zamore PD, Tuschl T, Sharp PA, Bartel DP: RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 2000, 101:25-33.
5. Nykanen A, Haley B, Zamore PD: ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 2001, 107:309-321.
6. Martinez J, Patkaniowska A, Urlaub H, Luhrmann R, Tuschl T: Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 2002, 110:563-574.
7. Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001, 411:494-498.
8. Brummelkamp TP, Bernards R, Agami R: A system for stable expression of short interfering RNAs in mammalian cells. Science 2002, 296:550-553.
9. Paul CP, Good PD, Winer I, Engelke DR: Effective expression of small interfering RNA in human cells. Nat Biotechnol 2002, 20:505-508.
10. Haasnoot PCJ, Berkhout B: RNA interference: Its use as antiviral therapy. In Handbook of Experimental Pharmacology Heidelberg, Springer-Verlag Berlin Heidelberg; 2006:117-150.
11. Coburn GA, Cullen BR: Potent and specific inhibition of human immunodeficiency virus type I replication by RNA interference. J Virol 2002, 76:9225-9231.
12. Jacque JM, Triques K, Stevenson M: Modulation of HIV-1 replication by RNA interference. Nature 2002, 418:435-438.
13. Lee NS, Dohjima T, Bauer G, Li H, Li MJ, Ehsani A, Salvaterra P, Rossi J: Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat Biotechnol 2002, 20:500-505.
14. Novina CD, Murray MF, Dykxhoorn DM, Beresford PJ, Riess J, Lee SK, Collman RG, Lieberman J, Shankar P, Sharp PA: siRNA-directed inhibition of HIV-1 infection. Nat Med 2002, 8:681-686.
15. Qin XF, An DS, Chen ISY, Baltimore D: Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci USA 2003, 100:183-188.
16. Capodici J, Kariko K, Weissman D: Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference. J Immunol 2002, 169:5196-5201.
17. Surabhi RM, Gaynor RB: RNA interference directed against viral and cellular targets inhibits human immunodeficiency virus type I replication. J. Virol 2002, 76:12963-12973.
18. Hu WY, Myers CP, Kilzer JM, Pfaff SL, Bushman FD: Inhibition of retroviral pathogenesis by RNA interference. Curr Biol 2002, 12:1301-1311.
19. Dave RS, Pomerantz RJ: Antiviral effects of human immunodeficiency virus type I-specific small interfering RNAs against targets conserved in select neurotropic viral strains. J Virol 2004, 78:13687-13696.
20. Park WS, Hayafune M, Miyano-Kurosaki N, Takaku H: Specific HIV-1 env gene silencing by small interfering RNAs in human peripheral blood mononuclear cells. Gene Ther 2003, 10:2046-2050.
21. Banerjea A, Li MJ, Bauer G, Remling L, Lee NS, Rossi J, Akkina R: Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages. Mol Ther 2003, 8:62-71.
22. Boden D, Pusch O, Lee F, Tucker L, Ramratnam B: Human immunodeficiency virus type I escape from RNA interference. J Virol 2003, 77:11531-11535.
23. Boden D, Pusch O, Lee F, Tucker L, Ramratnam B: Efficient gene transfer of HIV-1-specific short hairpin RNA into human lymphocytic cells using recombinant adeno-associated virus vectors. Mol Ther 2004, 9:396-402.
24. Das AT, Brummelkamp TR, Westerhout EM, Vink M, Madiredjo M, Bernards R, Berkhout B: Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J Virol 2004, 78:2601-2605 [http://jvi.asm.org/cgi/content/abstract/78/5/2601].
25. Lee MT, Coburn GA, McClure MO, Cullen BR: Inhibition of human immunodeficiency virus type I replication in primary macrophages by using Tat- or CCR5-specific small interfering RNAs expressed from a lentivirus vector. J Virol 2003, 77:11964-11972.
26. Unwalla HJ, Li MJ, Kim JD, Li HT, Ehsani A, Alluin J, Rossi JJ: Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA. Nat Biotechnol 2004, 22:1573-1578.
27. Lee SK, Dykxhoorn DM, Kumar P, Ranjbar S, Song E, Maliszewski LE, Francois-Bongarcon V, Goldfeld A, Swamy NM, Lieberman J, Shankar P: Lentiviral delivery of short hairpin RNAs protects CD4 T cells from multiple clades and primary isolates of HIV. Blood 2005, 106:818-826.
28. Anderson J, Banerjea A, Akkina R: Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance. Oligonucleotides 2003, 13:303-312.
29. Westerhout EM, Ooms M, Vink M, Das AT, Berkhout B: HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Nucleic Acids Res 2005, 33:796-804.
30. Berkhout B: RNA interference as an antiviral approach: targeting HIV-1. Current Opinion in Molecular Therapeutics 2005, 6:141-145.
31. Lee NS, Rossi JJ: Control of HIV-1 replication by RNA interference. Virus Res 2004, 102:53-58.
32. Ter Brake O, Berkhout B: A novel approach for inhibition of HIV-1 by RNA interference: counteracting viral escape with a second generation of siRNAs. Journal of RNAi and Gene Silencing 2005, 1(2):56-65.
33. Joshi PJ, North TW, Prasad VR: Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication. Mol Ther 2005, 11:677-686.
34. Nishitsuji H, Ikeda T, Miyoshi H, Ohashi T, Kannagi M, Masuda T: Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells. Microbes Infect 2004, 6:76-85.
35. Bantounas I, Phylactou LA, Uney JB: RNA interference and the use of small interfering RNA to study gene function in mammalian systems. J Mol Endocrinol 2004, 33:545-557.
36. Boden D, Pusch O, Lee F, Tucker L, Shank PR, Ramratnam B: Promoter choice affects the potency of HIV-1 specific RNA interference. Nucleic Acids Res 2003, 31:5033-5038.
37. Schmitz A, Lund AH, Hansen AC, Duch M, Pedersen FS: Target-cell-derived tRNA-like primers for reverse transcription support retroviral infection at low efficiency. Virol 2002, 297:68-77.
38. Zhou N, Fang J, Mukhtar M, Acheampong E, Pomerantz RJ: Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4. Gene Ther 2004, 11:1703-1712.
39. Seppen J, Rijnberg M, Cooreman MP, Oude Elferink RP: Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes. J Hepatol 2002, 36:459-465.
40. Dull T, Zufferey R, Kelly M, Mandel RJ, Nguyen M, Trono D, Naldini L: A third-generation lentivirus vector with a conditional packaging system. J Virol 1998, 72:8463-8471.
41. Zufferey R, Dull T, Mandel RJ, Bukovsky A, Quiroz D, Naldini L, Trono D: Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol 1998, 72:9873-9880.