Tandem repeat mutation, global DNA methylation, and regulation of DNA methyltransferases in cultured mouse embryonic fibroblast cells chronically exposed to chemicals with different modes of action

Environmental and Molecular Mutagenesis

Volumn 49, Issue 1, 2008, Pages 26-35

  Yauk, Carole L ^a,d   Polyzos, Aris ^b   Rowan Carroll, Andrea ^a   Kortubash, Igor ^c   Williams, Andrew ^a   Kovalchuk, Olga ^c  

^a HEALTH CANADA   (Canada)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF LETHBRIDGE   (Canada)

^d Environmental Health Center   (Canada)

Author keywords

DNA methyltransferases; Expanded simple tandem repeat; Methylation; Mutation

Indexed keywords

AZACITIDINE; BENZO[A]PYRENE; CISPLATIN; DNA METHYLTRANSFERASE; ETHYLNITROSOUREA; ETOPOSIDE; OKADAIC ACID;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA METHYLATION; DNA REPAIR; DNA SEQUENCE; EMBRYO; EMBRYO CELL; ENZYME REGULATION; FIBROBLAST; GENE EXPRESSION; GENE MUTATION; MISMATCH REPAIR; MOUSE; MUTATION RATE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL LINE; CELLS, CULTURED; DNA; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA MODIFICATION METHYLASES; EMBRYO, MAMMALIAN; FIBROBLASTS; GENE EXPRESSION REGULATION; MICE; MICE, INBRED C3H; MUTAGENS; MUTATION; TANDEM REPEAT SEQUENCES; TIME;

EID: 39749133599     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20359     Document Type: Article

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