Combined Functional and Positional Gene Information for the Identification of Susceptibility Variants in Celiac Disease

Gastroenterology

Volumn 134, Issue 3, 2008, Pages 738-746

  Castellanos Rubio, Ainara ^a   Martin Pagola, Ainhoa ^a   Santín, Izortze ^a   Hualde, Idoia ^b   Aransay, Ana María ^c   Castaño, Luis ^a,d   Vitoria, Juan Carlos ^a,d   Bilbao, Jose Ramon ^a,d  

^a HOSPITAL DE CRUCES   (Spain)

^b HOSPITAL TXAGORRITXU   (Spain)

^c CIC BIOGUNE   (Spain)

^d UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQ2 ANTIGEN;

ADOLESCENT; ARTICLE; CELIAC DISEASE; CHILD; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCUS; GENETIC LINKAGE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; HUMAN TISSUE; IMMUNE MEDIATED INJURY; INFANT; INTESTINE BIOPSY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 39749093221     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2007.11.041     Document Type: Article

References (48)

1. L. Castano E. Blarduni L. Ortiz Prospective population screening for celiac disease: high prevalence in the first 3 years of life J Pediatr Gastroenterol Nutr 39 2004 80 84
2. D.A. Van Heel K. Hunt L. Greco Genetics in coeliac disease Best Pract Res Clin Gastroenterol 19 2005 323 339
3. O. Molberg S.N. Mcadam R. Korner Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease Nat Med 4 1998 713 717
4. B.A. Lie L.M. Sollid H. Ascher A gene telomeric of the HLA class I region is involved in predisposition to both type 1 diabetes and coeliac disease Tissue Antigens 54 1999 162 168
5. J.R. Bilbao B. Calvo A.M. Aransay Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac disease Genes Immun 7 2006 550 554
6. I. Djilali-Saiah J. Schmitz E. Harfouch-Hammoud CTLA-4 gene polymorphism is associated with predisposition to coeliac disease Gut 43 1998 187 189
7. A. Martin-Pagola G. Perez de Nanclares J.C. Vitoria No association of CTLA4 gene with celiac disease in the Basque population J Pediatr Gastroenterol Nutr 37 2003 142 145
8. B. Rueda A. Martinez M.A. Lopez-Nevot A functional variant of IFNgamma gene is associated with coeliac disease Genes Immun 5 2004 517 519
9. M.C. Wapenaar M.J. Van Belzen J.H. Fransen The interferon gamma gene in celiac disease: augmented expression correlates with tissue damage but no evidence for genetic susceptibility J Autoimmun 23 2004 183 190
10. D.A. Van Heel L. Franke K.A. Hunt A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21 Nat Genet 39 2007 827 829
11. F. Zhong C.C. McCombs J.M. Olson An autosomal screen for genes that predispose to celiac disease in the western counties of Ireland Nat Genet 14 1996 329 333
12. L. Greco G. Corazza M.C. Babron Genome search in celiac disease Am J Hum Genet 62 1998 669 675
13. A.L. King J.Y. Yiannakou P.M. Brett A genome-wide family-based linkage study of coeliac disease Ann Hum Genet 64 2000 479 490
14. J. Liu S.H. Juo P. Holopainen Genomewide linkage analysis of celiac disease in Finnish families Am J Hum Genet 70 2002 51 59
15. S. Popat S. Bevan C.P. Braegger Genome screening of coeliac disease J Med Genet 39 2002 328 331
16. C.P. Garner Y.C. Ding L. Steele Genome-wide linkage analysis of 160 North American families with celiac disease Genes Immun 8 2007 108 114
17. A.W. Ryan J.M. Thornton K. Brophy Haplotype variation at the IBD5/SLC22A4 locus (5q31) in coeliac disease in the Irish population Tissue Antigens 64 2004 195 198
18. A.W. Ryan J.M. Thornton K. Brophy Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1 Tissue Antigens 65 2005 150 155
19. A.J. Monsuur P.I. de Bakker B.Z. Alizadeh Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect Nat Genet 37 2005 1341 1344
20. A.A. Van Bodegraven C.R. Curley K.A. Hunt Genetic variation in myosin IXB is associated with ulcerative colitis Gastroenterology 131 2006 1768 1774
21. K.A. Hunt A.J. Monsuur W.L. McArdle Lack of association of MYO9B genetic variants with coeliac disease in a British cohort Gut 55 2006 969 972
22. S.S. Amundsen A.J. Monsuur M.C. Wapenaar Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort Hum Immunol 67 2006 341 345
23. M. Giordano C. Marano M. Mellai A family-based study does not confirm the association of MYO9B with celiac disease in the Italian population Genes Immun 7 2006 606 608
24. G. Cirillo M.R. Di Domenico I. Corsi Do MYO9B genetic variants predispose to coeliac disease? An association study in a cohort of South Italian children Dig Liver Dis 39 2007 228 231
25. I. Santin A. Castellanos-Rubio G. Perez de Nanclares Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4 Genes Immun 8 2002 171 176
26. K. Juuti-Uusitalo M. Maki K. Kaukinen cDNA microarray analysis of gene expression in coeliac disease jejunal biopsy samples J Autoimmun 22 2002 249 265
27. B. Diosdado M.C. Wapenaar L. Franke A microarray screen for novel candidate genes in coeliac disease pathogenesis Gut 53 2004 944 951
28. L. Prokunina M.E. Alarcon-Riquelme Regulatory SNPs in complex diseases: their identification and functional validation Expert Rev Mol Med 6 2004 1 15
29. A. Martin-Pagola G. Perez-Nanclares L. Ortiz MICA response to gliadin in intestinal mucosa from celiac patients Immunogenetics 56 2004 549 554
30. G.L. Argraves S. Jani J.L. Barth ArrayQuest: a web resource for the analysis of DNA microarray data BMC Bioinformatics 6 2005 287
31. H.Y. Yuan J.J. Chiou W.H. Tseng FASTSNP: an always up-to-date and extendable service for SNP function analysis and prioritization Nucleic Acids Res 34 2006 635 641
32. L. Conde J.M. Vaquerizas H. Dopazo PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes Nucleic Acids Res 34 2006 621 625
33. H. Xu S.G. Gregory E.R. Hauser SNPselector: a web tool for selecting SNPs for genetic association studies Bioinformatics 21 2005 4181 4186
34. B.M. Hemminger B. Saelim P.F. Sullivan TAMAL: an integrated approach to choosing SNPs for genetic studies of human complex traits Bioinformatics 22 2006 626 627
35. S. Purcell B. Neale K. Todd-Brown PLINK: a toolset for whole-genome association and population-based linkage analysis Am J Hum Genet 81 2007 559 575
36. M. Buchholz A. Biebl A. Neesse SERPINE2 (protease nexin I) promotes extracellular matrix production and local invasion of pancreatic tumors in vivo Cancer Res 63 2003 4945 4951
37. V. Villanacci F. Facchetti N. Pillan Expression of cell adhesion molecules in jejunum biopsies of children with coeliac disease It J Gastroenterol 25 1993 109 116
38. O.P. Kristiansen Z.M. Larsen F. Pociot CTLA-4 in autoimmune diseases—a general susceptibility gene to autoimmunity? Genes Immun 1 2000 170 184
39. P. Holopainen A.T. Naluai S. Moodie Candidate gene region 2q33 in European families with coeliac disease Tissue Antigens 63 2004 212 222
40. K. Hunt D. McGovern P. Kumar A common CTLA4 haplotype associated with coeliac disease Eur J Hum Genet 13 2005 440 444
41. D. Penkov P. Di Rosa L. Fernandez-Diaz Involvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursors Mol Cell Biol 25 2005 10768 10781
42. H. Bastians H. Ponstingl The novel human protein serine/threonine phosphatase 6 is a functional homologue of budding yeast Sit4p and fission yeast ppe1, which are involved in cell cycle regulation J Cell Sci 109 1996 2865 2874
43. M. Kanehisa S. Goto M. Hattori From genomics to chemical genomics: new developments in KEGG Nucleic Acids Res 34 2006 D354 D357
44. R. Przemioslo N.A. Wright G. Elia Analysis of crypt cell proliferation in coeliac disease using MI-B1 antibody shows an increase in growth fraction Gut 36 1995 22 27
45. K. Stolle M. Schnoor G. Fuellen Cloning, cellular localization, genomic organization, and tissue-specific expression of the TGFbeta1-inducible SMAP-5 gene Gene 23 2005 119 130
46. G.J. Prud’homme C.A. Piccirillo The inhibitory effects of transforming growth factor-beta-1 (TGF-beta1) in autoimmune diseases J Autoimmun 14 2000 23 42
47. P. Michl A.R. Ramjaun O.E. Pardo CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness J Cancer Cell 7 2005 521 532
48. S.Y. Kim New target against inflammatory diseases: transglutaminase 2 Arch Immunol Ther Exp (Warsz) 52 2004 332 337