Attenuation of pulmonary hypertension, but not emphysematous change, by breeding emphysema model mice at sea level

Cytokine

Volumn 41, Issue 3, 2008, Pages 286-292

  Fujita, Masaki ^a,b   Ikegame, Satoshi ^a   Ye, Qing ^a   Harada, Eiji ^a   Ouchi, Hiroshi ^a   Inoshima, Ichiro ^a   Watanabe, Kentaro ^b   Mason, Robert J ^c   Nakanishi, Yoichi ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b FUKUOKA UNIVERSITY   (Japan)

^c NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

Author keywords

Bacterial clearance; Cytokine; Inflammation; Receptor; TNF

Indexed keywords

VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; HEART RIGHT VENTRICLE HYPERTROPHY; LUNG EMPHYSEMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY HYPERTENSION;

ALTITUDE; ANIMALS; BREEDING; DISEASE MODELS, ANIMAL; FEMALE; HYPERTENSION, PULMONARY; LUNG; MALE; MICE; MICE, TRANSGENIC; PULMONARY EMPHYSEMA; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

BACTERIA (MICROORGANISMS); MUS; MUS MUSCULUS;

EID: 39749087535     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2007.12.004     Document Type: Article

References (31)

1. Nelson S., Bagby G.J., Bainton B.G., Wilson L.A., Thompson J.J., and Summer W.R. Compartmentalization of intra-alveolar and systemic lipopolysaccharide-induced tumor necrosis factor and the pulmonary inflammatory response. J Infect Dis 159 (1989) 189-194
2. Bazzoni F., and Beutler B. The tumor necrosis factor ligand and receptor families. N Engl J Med 334 (1996) 1717-1725
3. Johnson J., Brigham K.L., Jesmok G., and Meyrick B. Morphologic changes in lungs of anesthetized sheep following intravenous infusion of recombinant tumor necrosis factor α. Am Rev Respir Dis 144 (1991) 179-186
4. Miyazaki Y., Araki K., Vesin C., Garcia I., Kapanci Y., Whitsett J.A., et al. Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis. J Clin Invest 96 (1995) 250-259
5. Piguet P.F., Collart M.A., Grau G.E., Kapanci Y., and Vassalli P. Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis. J Exp Med 170 (1989) 655-663
6. Piguet P.F., Collart M.A., Grau G.E., Sappino A.P., and Vassalli P. Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Nature 344 (1990) 245-247
7. Fujita M., Shannon J.M., Irvin C.G., Fagan K.A., Cool C., Augustin A., et al. Overexpression of tumor necrosis factor-a produces an increase in lung volumes and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 280 (2001) L39-L49
8. Fujita M., Mason R.J., Cool C., Shannon J.M., Hara N., and Fagan K.A. Pulmonary hypertension in TNF-alpha-overexpressing mice is associated with decreased VEGF gene expression. J Appl Physiol 93 (2002) 2162-2170
9. Lundblad L.K.A., Thompson-Figueroa J., Leclair T., Sullivan M.J., Poynter M.E., Irvin C.G., et al. Tumor necrosis factor-{alpha} overexpression in lung disease: a single cause behind a complex phenotype. Am J Respir Crit Care Med 171 (2005) 1363-1370
10. King Jr. T.E., Tooze J.A., Schwarz M.I., Brown K.R., and Cherniack R.M. Predicting survival in idiopathic pulmonary fibrosis: scoring system and survival model. Am J Respir Crit Care Med 164 (2001) 1171-1181
11. Oswald-Mammosser M., Weitzenblum E., Quoix E., Moser G., Chaouat A., Charpentier C., et al. Prognostic factors in COPD patients receiving long-term oxygen therapy. Importance of pulmonary artery pressure. Chest 107 (1995) 1193-1198
12. Fujita M., Ye Q., Ouchi H., Nakashima N., Hamada N., Hagimoto N., et al. Retinoic acid fails to reverse emphysema in adult mouse models. Thorax 59 (2004) 224-230
13. Irvin C.G., Tu Y.P., Sheller J.R., and Funk C.D. 5-Lipoxygenase products are necessary for ovalbumin-induced airway responsiveness in mice. Am J Phsyiol 272 (1997) L1053-L1058
14. Claffey K.P., Wilkison W.O., and Spiegelman B.M. Vascular endothelial growth factor: regulation by cell differentiation and activated second messenger pathways. J Biol Chem 267 (1992) 16317-16322
15. Millauer B., Wizigmann-Voos S., Schurch H., Martinez R., Moller N.P., Risau W., et al. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72 (1993) 835-846
16. Finnerty H., Kelleher K., Morris G.E., Bean K., Merberg D.M., Kriz R., et al. Molecular cloning of murine FLT and FLT4. Oncogene 8 (1993) 2293-2298
17. Katzenstein A.L., and Myers J.L. Idiopathic pulmonary fibrosis. Clinical relevance of pathologic classification. Am J Respir Crit Care Med 157 (1998) 1301-1315
18. Fagan K.A., Fouty B.W., Tyler R.C., Morris Jr. K.G., Hepler L.K., Sato K., et al. The pulmonary circulation of homozygous or heterozygous eNOS-null mice is hyperresponsive to mild hypoxia. J Clin Invest 103 (1999) 291-299
19. Balasubramaniam V., Tang J.R., Maxey A., Plopper C.G., and Abman S.H. Mild hypoxia impairs alveolarization in the endothelial nitric oxide synthase-deficient mouse. Am J Physiol Lung Cell Mol Physiol 284 (2003) L964-L971
20. Moore L.G., Rohr A.L., Maisenbach J.K., and Reeves J.T. Emphysema mortality is increased in Colorado residents at high altitude. Am Rev Respir Dis 126 (1982) 225-228
21. Hirose S., Hosoda Y., Furuya S., Otsuki T., and Ikeda E. Expression of vascular endothelial growth factor and its receptors correlates closely with formation of the plexiform lesion in human pulmonary hypertension. Pathol Int 50 (2000) 472-479
22. Tuder R.M., Chacon M., Alger L., Wang J., Taraseviciene-Stewart L., Kasahara Y., et al. Expression of angiogenesis-related molecules in plexiform lesions in severe pulmonary hypertension: evidence for a process of disordered angiogenesis. J Pathol 195 (2001) 367-374
23. Christou H., Yoshida A., Arthur V., Morita T., and Kourembanas S. Increased vascular endothelial growth factor production in the lungs of rats with hypoxia-induced pulmonary hypertension. Am J Respir Cell Mol Biol 18 (1998) 768-776
24. Partovian C., Adnot S., Eddahibi S., Teiger E., Levame M., Dreyfus P., et al. Heart and lung VEGF mRNA expression in rats with monocrotaline- or hypoxia-induced pulmonary hypertension. Am J Physiol Heart Circ Physiol 275 (1998) H1948-H1956
25. Asahara T., Chen D., Tsurumi Y., Kearney M., Rossow S., Passeri J., et al. Accelerated restitution of endothelial integrity and endothelium-dependent function after phVEGF165 gene transfer. Circulation 94 (1996) 3291-3302
26. Gerber H.P., Dixit V., and Ferrara N. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem 273 (1998) 13313-13316
27. Lundby C., Pilegaard H., Andersen J.L., van Hall G., Sander M., and Calbet J.A. Acclimatization to 4100 m does not change capillary density or mRNA expression of potential angiogenesis regulatory factors in human skeletal muscle. J Exp Biol 207 (2004) 3865-3871
28. Dorward D.A., Thompson A.A., Baillie J.K., MacDougall M., and Hirani N. Change in plasma vascular endothelial growth factor during onset and recovery from acute mountain sickness. Respir Med 101 (2007) 587-594
29. Voelkel N., and Taraseviciene-Stewart L. Emphysema: an autoimmune vascular disease?. Proc Am Thorac Soc 2 (2005) 23-25
30. Kasahara Y., Tuder R.M., Taraseviciene-Stewart L., Le Cras T.D., Abman S., Hirth P.K., et al. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J Clin Invest 106 (2000) 1311-1319
31. D'hulst A.I., Maes T., Bracke K.R., Demedts I.K., Tournoy K.G., Joos G.F., et al. Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required?. Respir Res 6 (2005) 147