Involvement of cytochrome P450 1A in sanguinarine detoxication

Toxicology Letters

Volumn 151, Issue 2, 2004, Pages 375-387

  Vrba, Jiří ^a   Kosina, Pavel ^a   Ulrichová, Jitka ^a   Modrianský, Martin ^a  

^a PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

Cytochrome P450; Human hepatic microsomes; NADPH:CYP reductase; Sanguinarine; Toxicity

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3 METHYLCHOLANTHRENE; ALKALOID DERIVATIVE; BENZO[C]PHENANTHRIDINE DERIVATIVE; BETA NAPHTHOFLAVONE; CYTOCHROME P450 1A; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; ETHOXYRESORUFIN; LACTATE DEHYDROGENASE; RECOMBINANT ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE; SANGIUNARINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL STRAIN HEPG2; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETOXIFICATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LIVER CELL CULTURE; LIVER METABOLISM; LIVER MICROSOME; LIVER TOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; TIME; TOXICITY TESTING;

EID: 2942565984     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2004.03.005     Document Type: Article

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