A topoisomerase II inhibitor, NK109, induces DNA single- and double-strand breaks and apoptosis

Japanese Journal of Cancer Research

Volumn 87, Issue 10, 1996, Pages 1086-1091

  Fukuda, Minoru ^a   Inomata, Motoko ^b   Nishio, Kazuto ^b   Fukuoka, Kazuya ^b   Kanzawa, Fumihiko ^b   Arioka, Hitoshi ^b   Ishida, Tomoyuki ^b   Fukumoto, Hisao ^b   Kurokawa, Hirokazu ^b   Oka, Mikio ^c   Saijo, Nagahiro ^b  

^a NATIONAL CANCER CENTER HOSPITAL   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^c NAGASAKI UNIVERSITY   (Japan)

Author keywords

Apoptosis; DNA strand break; NK109; Topoisomerase

Indexed keywords

7 HYDROXY 8 METHOXY 5 METHYL 2,3 METHYLENEDIOXYBENZO[C]PHENANTHRIDINIUM HYDROGEN SULFATE; BENZO[C]PHENANTHRIDINE DERIVATIVE; CYCLOHEXIMIDE; DACTINOMYCIN; DNA; DNA FRAGMENT; DNA TOPOISOMERASE (ATP HYDROLYSING); DOUBLE STRANDED DNA; ENZYME INHIBITOR; ETOPOSIDE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; ZINC;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA STRAND BREAKAGE; HUMAN; HUMAN CELL; LUNG SMALL CELL CANCER; NUCLEOSOME; PRIORITY JOURNAL;

EID: 10544223738     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1996.tb03114.x     Document Type: Article

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