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Volumn 15, Issue 5, 2008, Pages 329-337

Progress and prospects: Gene therapy for performance and appearance enhancement

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ERYTHROPOIETIN; ESTROGEN; ESTROGEN RECEPTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLUCOCORTICOID; GROWTH HORMONE; KALININ; LENTIVIRUS VECTOR; LEPTIN; MYOSTATIN; PARVOVIRUS VECTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLASMID VECTOR; PROOPIOMELANOCORTIN; PROTEIN KINASE C; RAPAMYCIN; SOMATOMEDIN C; SONIC HEDGEHOG PROTEIN; TETRACYCLINE; VASCULOTROPIN; VIRUS VECTOR;

EID: 39449132142     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3303100     Document Type: Review
Times cited : (14)

References (80)
  • 1
    • 13844253826 scopus 로고    scopus 로고
    • Cat and mouse in regulating genetic 'ehancement'
    • Miller H. Cat and mouse in regulating genetic 'ehancement'. Nat Biotechnol 2005; 23: 171-172.
    • (2005) Nat Biotechnol , vol.23 , pp. 171-172
    • Miller, H.1
  • 2
    • 13544250817 scopus 로고    scopus 로고
    • Engineering genetic injustice
    • Wenz P. Engineering genetic injustice. Bioethics 2005; 19: 1-11.
    • (2005) Bioethics , vol.19 , pp. 1-11
    • Wenz, P.1
  • 3
    • 39449095862 scopus 로고    scopus 로고
    • The American Society for Aesthetic Plastic Surgery 11.5 Million. Cosmetic Procedures in 2006. (http://www.surgery.org/press/ news-release-php?iid=465) last accessed 1/3/08.
    • The American Society for Aesthetic Plastic Surgery 11.5 Million. Cosmetic Procedures in 2006. (http://www.surgery.org/press/ news-release-php?iid=465) last accessed 1/3/08.
  • 4
    • 33751204733 scopus 로고    scopus 로고
    • Gene therapy. An ethical profile of a new medical territory
    • Fuchs M. Gene therapy. An ethical profile of a new medical territory. J Gene Med 2006; 8: 1358-1362.
    • (2006) J Gene Med , vol.8 , pp. 1358-1362
    • Fuchs, M.1
  • 6
    • 33746818809 scopus 로고    scopus 로고
    • Growth hormone therapy, for short stature: Is the benefit worth the burden?
    • Allen DB. Growth hormone therapy, for short stature: Is the benefit worth the burden? Pediatrics 2006; 118: 343-348.
    • (2006) Pediatrics , vol.118 , pp. 343-348
    • Allen, D.B.1
  • 7
    • 11844303500 scopus 로고    scopus 로고
    • Recent developments in gene transfer risk and ethics
    • Kimmelman J. Recent developments in gene transfer risk and ethics. BMJ 2005; 330: 79-82
    • (2005) BMJ , vol.330 , pp. 79-82
    • Kimmelman, J.1
  • 8
    • 33750006826 scopus 로고    scopus 로고
    • The ethics of gene therapy
    • Chan S, Harris J. The ethics of gene therapy. Curr Opin Mol Ther 2006; 8: 377-383.
    • (2006) Curr Opin Mol Ther , vol.8 , pp. 377-383
    • Chan, S.1    Harris, J.2
  • 9
    • 33645127443 scopus 로고    scopus 로고
    • Genetic medicines: Treatment strategies for hereditary disorders
    • O'Connor TP, Crystal RG. Genetic medicines: Treatment strategies for hereditary disorders. Nat Rev Genet 2006; 7: 261-276.
    • (2006) Nat Rev Genet , vol.7 , pp. 261-276
    • O'Connor, T.P.1    Crystal, R.G.2
  • 10
    • 14844331756 scopus 로고    scopus 로고
    • Long-term inducible gene expression in the eye via adeno-associated virus gene transfer in nonhuman primates
    • Lebherz C, Auricchio A, Maguire AM, Rivera VM; Tang W, Grant RL et al Long-term inducible gene expression in the eye via adeno-associated virus gene transfer in nonhuman primates. Hum Gene Ther 2005; 16: 178-186.
    • (2005) Hum Gene Ther , vol.16 , pp. 178-186
    • Lebherz, C.1    Auricchio, A.2    Maguire, A.M.3    Rivera, V.M.4    Tang, W.5    Grant, R.L.6
  • 12
    • 13544262341 scopus 로고    scopus 로고
    • Long-term pharmacologically regulated expression of erythropoietin in phrates following AAV-mediated gene transfer
    • Rivera VM, Gao GP, Grant RL, Schnell MA, Zoltick PW, Rozamus LW et al Long-term pharmacologically regulated expression of erythropoietin in phrates following AAV-mediated gene transfer. Blood 2005; 105: 1424-1430.
    • (2005) Blood , vol.105 , pp. 1424-1430
    • Rivera, V.M.1    Gao, G.P.2    Grant, R.L.3    Schnell, M.A.4    Zoltick, P.W.5    Rozamus, L.W.6
  • 13
    • 21244443038 scopus 로고    scopus 로고
    • Salivary glands as a potential gene transfer target for gene therapeutics of some. monogenetic endocrine disorders
    • Voutetakis A, Bossis I, Kok MR, Zhang W, Wang J, Cotrim AP et al. Salivary glands as a potential gene transfer target for gene therapeutics of some. monogenetic endocrine disorders J Endocrinol 2005; 185: 363-372.
    • (2005) J Endocrinol , vol.185 , pp. 363-372
    • Voutetakis, A.1    Bossis, I.2    Kok, M.R.3    Zhang, W.4    Wang, J.5    Cotrim, A.P.6
  • 14
    • 33645840126 scopus 로고    scopus 로고
    • Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors
    • Stieger K, Le MG, Lasne F, Weber M, Deschamps JY, Nivard D et al. Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors. Mol Ther 2006; 13: 967-975.
    • (2006) Mol Ther , vol.13 , pp. 967-975
    • Stieger, K.1    Le, M.G.2    Lasne, F.3    Weber, M.4    Deschamps, J.Y.5    Nivard, D.6
  • 15
    • 33750611942 scopus 로고    scopus 로고
    • Adipose-tissue as a novel target for in vivo gene transfer by, adeno-associated viral vectors
    • Mizukami H, Mimuro J, Ogura T, Okada T. Urabe M, Kume, A et al. Adipose-tissue as a novel target for in vivo gene transfer by, adeno-associated viral vectors. Hum Gene Ther 2006; 17: 921-928.
    • (2006) Hum Gene Ther , vol.17 , pp. 921-928
    • Mizukami, H.1    Mimuro, J.2    Ogura, T.3    Okada, T.4    Urabe, M.5    Kume, A.6
  • 16
    • 29944446086 scopus 로고    scopus 로고
    • Wang J, Voutetakis A, 'Papa M, Rivera VM, Clackson T, Lodde BM et al Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands. Gene Therapy 2006; 13: 187-190.
    • Wang J, Voutetakis A, 'Papa M, Rivera VM, Clackson T, Lodde BM et al Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands. Gene Therapy 2006; 13: 187-190.
  • 17
    • 33748702530 scopus 로고    scopus 로고
    • Correction of enemia in uremic rats by intramuscular injection of lentivirus carrying, an erythropoietin, gene
    • Oh TK, Quan GH, Kim HY, Park F, Kim ST. Correction of enemia in uremic rats by intramuscular injection of lentivirus carrying, an erythropoietin, gene. Am J Nephrol 2006; 26: 326-334.
    • (2006) Am J Nephrol , vol.26 , pp. 326-334
    • Oh, T.K.1    Quan, G.H.2    Kim, H.Y.3    Park, F.4    Kim, S.T.5
  • 18
    • 34447568332 scopus 로고    scopus 로고
    • G-CSF-lentivirus administration in rats provided sustained elevated neutrophil counts and subsequent EPO-lentivirus administration increased hematocrits
    • Brzezinski M, Yanay O, Waldron L, Barry SC, Osborne WR. G-CSF-lentivirus administration in rats provided sustained elevated neutrophil counts and subsequent EPO-lentivirus administration increased hematocrits. J Gene Med 2007; 9: 571-578.
    • (2007) J Gene Med , vol.9 , pp. 571-578
    • Brzezinski, M.1    Yanay, O.2    Waldron, L.3    Barry, S.C.4    Osborne, W.R.5
  • 19
  • 20
    • 12744261398 scopus 로고    scopus 로고
    • Inducible production of erythropoietin using intramuscular injection of block copolymer/DNA formulation
    • Richard P, Pollard H, Lanctin C, Bello-Roufai M, Desigaux L, Escande D et al. Inducible production of erythropoietin using intramuscular injection of block copolymer/DNA formulation. J Gene Med 2005; 7: 80-86.
    • (2005) J Gene Med , vol.7 , pp. 80-86
    • Richard, P.1    Pollard, H.2    Lanctin, C.3    Bello-Roufai, M.4    Desigaux, L.5    Escande, D.6
  • 22
    • 22644444463 scopus 로고    scopus 로고
    • Ex vivo transduction of human dermal tissue structures for autologous implantation production and delivery of therapeutic proteins
    • Brill-Almon E, Stern B, Afik D, Kaye J, Langer N, Bellomo S et al. Ex vivo transduction of human dermal tissue structures for autologous implantation production and delivery of therapeutic proteins. Mol Ther 2005; 12: 274-282.
    • (2005) Mol Ther , vol.12 , pp. 274-282
    • Brill-Almon, E.1    Stern, B.2    Afik, D.3    Kaye, J.4    Langer, N.5    Bellomo, S.6
  • 24
    • 22644433564 scopus 로고    scopus 로고
    • Long-term expression of erythropoietin from myoblasts immobilized in biocompatible and neovascularized microcapsules
    • Orive G, De CM, Ponce S, Hernandez RM, Gascon AR, Bosch M et al. Long-term expression of erythropoietin from myoblasts immobilized in biocompatible and neovascularized microcapsules. Mol Ther 2005; 12: 283-289.
    • (2005) Mol Ther , vol.12 , pp. 283-289
    • Orive, G.1    De, C.M.2    Ponce, S.3    Hernandez, R.M.4    Gascon, A.R.5    Bosch, M.6
  • 25
    • 33646903235 scopus 로고    scopus 로고
    • Erythropoietin delivery by genetically engineered bone marrow stromal cells for correction of anemia in mice with chronic renal failure
    • Eliopoulos; N, Gagnon RF, Francois M, Galipeau J. Erythropoietin delivery by genetically engineered bone marrow stromal cells for correction of anemia in mice with chronic renal failure. J Am Soc Nephrol 2006; 17: 1576-1584.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1576-1584
    • Eliopoulos, N.1    Gagnon, R.F.2    Francois, M.3    Galipeau, J.4
  • 26
    • 15444367412 scopus 로고    scopus 로고
    • Insulin-like growth factor-I gene transfer by electroporation prevents skeletal muscle atrophy in glucocorticoid-treated rats
    • Schakman O, Gilson H, de Coninck V, Lause P, Verniers J, Havaux X et al. Insulin-like growth factor-I gene transfer by electroporation prevents skeletal muscle atrophy in glucocorticoid-treated rats. Endocrinology 2005; 146: 1789-1797.
    • (2005) Endocrinology , vol.146 , pp. 1789-1797
    • Schakman, O.1    Gilson, H.2    de Coninck, V.3    Lause, P.4    Verniers, J.5    Havaux, X.6
  • 27
    • 23844515285 scopus 로고    scopus 로고
    • Phenotypic improvement of dystrophic muscles by rAAV/microdystrophin vectors is augmented by Igf1 codelivery
    • Abmayr S, Gregorevic P, Allen JM, Chamberlain JS. Phenotypic improvement of dystrophic muscles by rAAV/microdystrophin vectors is augmented by Igf1 codelivery. Mol Ther 2005; 12 441-450.
    • (2005) Mol Ther , vol.12 , pp. 441-450
    • Abmayr, S.1    Gregorevic, P.2    Allen, J.M.3    Chamberlain, J.S.4
  • 28
    • 33846341159 scopus 로고    scopus 로고
    • Long-term stable expression of human growth hormone by rAAV promotes myocardial protection post-myocardial infarction
    • Kusano K, Tsutsumi Y, Dean J, Gavin M, Ma H, Silver M et al. Long-term stable expression of human growth hormone by rAAV promotes myocardial protection post-myocardial infarction. J Mol Cell Cardiol 2007; 42: 390-399.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 390-399
    • Kusano, K.1    Tsutsumi, Y.2    Dean, J.3    Gavin, M.4    Ma, H.5    Silver, M.6
  • 30
    • 34247166670 scopus 로고    scopus 로고
    • AAV-mediated delivery of a mutated myostatin propeptide ameliorates calpain- 3 but not alpha-sarcoglycan deficiency
    • Bartoli M, Poupiot J, Vulin A, Fougerousse F, Arandel L, Daniele N et al. AAV-mediated delivery of a mutated myostatin propeptide ameliorates calpain- 3 but not alpha-sarcoglycan deficiency. Gene Therapy 2007; 14, 733-740.
    • (2007) Gene Therapy , vol.14 , pp. 733-740
    • Bartoli, M.1    Poupiot, J.2    Vulin, A.3    Fougerousse, F.4    Arandel, L.5    Daniele, N.6
  • 32
    • 24944578263 scopus 로고    scopus 로고
    • Genetic enhancement of visual learning by activation of protein kinase C pathways in small groups of rat cortical neurons
    • Zhang GR, Wang X, Kong L, Lu XG, Lee B, Liu M et al. Genetic enhancement of visual learning by activation of protein kinase C pathways in small groups of rat cortical neurons. J Neurosci 2005; 25: 8468-8481.
    • (2005) J Neurosci , vol.25 , pp. 8468-8481
    • Zhang, G.R.1    Wang, X.2    Kong, L.3    Lu, X.G.4    Lee, B.5    Liu, M.6
  • 33
    • 22544464405 scopus 로고    scopus 로고
    • Suppression of fat deposition for the life time with gene therapy
    • Boghossian S, Lecklin A, Torto R, Kalra PS, Kalra SP. Suppression of fat deposition for the life time with gene therapy. Peptides 2005; 26: 1512-1519.
    • (2005) Peptides , vol.26 , pp. 1512-1519
    • Boghossian, S.1    Lecklin, A.2    Torto, R.3    Kalra, P.S.4    Kalra, S.P.5
  • 34
    • 21344466081 scopus 로고    scopus 로고
    • Leptin resistance exacerbates diet-induced obesity and is associated with diminished maximal leptin signalling capacity in rats
    • Scarpace PJ, Matheny M, Tumer N, Cheng KY, Zhang Y. Leptin resistance exacerbates diet-induced obesity and is associated with diminished maximal leptin signalling capacity in rats. Diabetologia 2005; 48: 1075-1083.
    • (2005) Diabetologia , vol.48 , pp. 1075-1083
    • Scarpace, P.J.1    Matheny, M.2    Tumer, N.3    Cheng, K.Y.4    Zhang, Y.5
  • 35
    • 20444421276 scopus 로고    scopus 로고
    • Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation
    • Lecklin A, Dube MG, Torto RN, Kalra RS, Kalra SP. Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation. Peptides 2005; 26: 1176-1187.
    • (2005) Peptides , vol.26 , pp. 1176-1187
    • Lecklin, A.1    Dube, M.G.2    Torto, R.N.3    Kalra, R.S.4    Kalra, S.P.5
  • 36
    • 27944502118 scopus 로고    scopus 로고
    • Central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight
    • Otukonyong EE, Dube MG, Torto R, Kalra PS, Kalra SP. Central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight. Peptides 2005; 26: 2559-2566.
    • (2005) Peptides , vol.26 , pp. 2559-2566
    • Otukonyong, E.E.1    Dube, M.G.2    Torto, R.3    Kalra, P.S.4    Kalra, S.P.5
  • 37
    • 33746886648 scopus 로고    scopus 로고
    • Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice
    • Ueno N, Inui A, Kalra PS, Kalra SP, Leptin transgene expression in the hypothalamus enforces euglycemia in diabetic, insulin-deficient nonobese Akita mice and leptin-deficient obese ob/ob mice. Peptides 2006; 27: 2332-2342.
    • (2006) Peptides , vol.27 , pp. 2332-2342
    • Ueno, N.1    Inui, A.2    Kalra, P.S.3    Kalra, S.P.4
  • 38
    • 33750948987 scopus 로고    scopus 로고
    • Hypothalamic clamp on insulin release by leptin-transgene expression
    • Boghossian S, Dube MG, Torto R, Kalra PS, Kalra SP. Hypothalamic clamp on insulin release by leptin-transgene expression. Peptides 2006; 27: 3245-3254.
    • (2006) Peptides , vol.27 , pp. 3245-3254
    • Boghossian, S.1    Dube, M.G.2    Torto, R.3    Kalra, P.S.4    Kalra, S.P.5
  • 39
    • 33846565392 scopus 로고    scopus 로고
    • Increased leptin expression in the dorsal vagal complex suppresses adiposity without affecting energy intake and metabolic hormones
    • Boghossian S, Lecklin A, Dube MG, Kalra PS, Kalra SP. Increased leptin expression in the dorsal vagal complex suppresses adiposity without affecting energy intake and metabolic hormones. Obesity (Silver Spring) 2006; 14: 1003-1009.
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 1003-1009
    • Boghossian, S.1    Lecklin, A.2    Dube, M.G.3    Kalra, P.S.4    Kalra, S.P.5
  • 41
    • 34547770365 scopus 로고    scopus 로고
    • Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin
    • Boghossian S, Ueno N, Dube MG, Kalra P, Kalra S. Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin. Neurobiol Aging 2007; 28: 1594-1604.
    • (2007) Neurobiol Aging , vol.28 , pp. 1594-1604
    • Boghossian, S.1    Ueno, N.2    Dube, M.G.3    Kalra, P.4    Kalra, S.5
  • 42
    • 33846447066 scopus 로고    scopus 로고
    • Leptin antagonist reveals an uncoupling between leptin receptor signal transducer and activator of transcription 3 signaling and metabolic responses with central leptin resistance
    • Scarpace PJ, Matheny M, Zhang Y, Cheng KY, Turner N. Leptin antagonist reveals an uncoupling between leptin receptor signal transducer and activator of transcription 3 signaling and metabolic responses with central leptin resistance. J Pharmacol Exp Ther 2007; 320: 706-712.
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 706-712
    • Scarpace, P.J.1    Matheny, M.2    Zhang, Y.3    Cheng, K.Y.4    Turner, N.5
  • 43
    • 27744596351 scopus 로고    scopus 로고
    • Hypothalamic pro-opiomelanocortin gene delivery ameliorates obesity and glucose intolerance in aged rats
    • Li G, Zhang Y, Wilsey JT, Scarpace PJ. Hypothalamic pro-opiomelanocortin gene delivery ameliorates obesity and glucose intolerance in aged rats. Diabetologia 2005; 48; 2076-2385.
    • (2005) Diabetologia , vol.48 , pp. 2076-2385
    • Li, G.1    Zhang, Y.2    Wilsey, J.T.3    Scarpace, P.J.4
  • 44
    • 34547103515 scopus 로고    scopus 로고
    • Melanocortin activation of nucleus of the solitary tract avoids anorectic tachyphylaxis and induces prolonged weight loss
    • Li G, Zhang Y, Rodrigues E, Zheng D, Matheny M, Cheng KY et al. Melanocortin activation of nucleus of the solitary tract avoids anorectic tachyphylaxis and induces prolonged weight loss. Am J Physiol Endocrinol Metab 2007; 293: E252-E258.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • Li, G.1    Zhang, Y.2    Rodrigues, E.3    Zheng, D.4    Matheny, M.5    Cheng, K.Y.6
  • 45
    • 34249932831 scopus 로고    scopus 로고
    • Lean rats with hypothalamic pro-opiomelanocortin overexpression exhibit greater diet-induced obesity and impaired central melanocortin responsiveness
    • Li G, Zhang Y, Cheng KY, Scarpace PJ. Lean rats with hypothalamic pro-opiomelanocortin overexpression exhibit greater diet-induced obesity and impaired central melanocortin responsiveness. Diabetologia 2007; 50: 1490-1499.
    • (2007) Diabetologia , vol.50 , pp. 1490-1499
    • Li, G.1    Zhang, Y.2    Cheng, K.Y.3    Scarpace, P.J.4
  • 47
    • 23844458442 scopus 로고    scopus 로고
    • Enhanced efficacy of cholesterol-minus sonic hedgehog in postnatal skin
    • Lou H, Crystal RG, LeopoId PL. Enhanced efficacy of cholesterol-minus sonic hedgehog in postnatal skin. Mol Ther 2005; 12: 575-578.
    • (2005) Mol Ther , vol.12 , pp. 575-578
    • Lou, H.1    Crystal, R.G.2    LeopoId, P.L.3
  • 48
    • 39449096189 scopus 로고    scopus 로고
    • The World Anti-doping Code. The 2006 Prohibited List. (http://www.wada-ama.org/rtecontent/document/2006_LIST.pdf) last accessed 1/3/08.
    • The World Anti-doping Code. The 2006 Prohibited List. (http://www.wada-ama.org/rtecontent/document/2006_LIST.pdf) last accessed 1/3/08.
  • 50
    • 27744596872 scopus 로고    scopus 로고
    • Azzazy HM, Mansour MM, Christenson RH. Doping in the recombinant era: strategies and counterstrategies. Clin Biochem 2005; 38: 959-965.
    • Azzazy HM, Mansour MM, Christenson RH. Doping in the recombinant era: strategies and counterstrategies. Clin Biochem 2005; 38: 959-965.
  • 51
    • 33745082133 scopus 로고    scopus 로고
    • Biochemistry, physiology, and complications of blood doping: Facts and speculation
    • Lippi G, Franchini M, Salvagno GL, Guidi GC. Biochemistry, physiology, and complications of blood doping: Facts and speculation. Crit Rev Clin Lab Sci 2006; 43: 349-391.
    • (2006) Crit Rev Clin Lab Sci , vol.43 , pp. 349-391
    • Lippi, G.1    Franchini, M.2    Salvagno, G.L.3    Guidi, G.C.4
  • 52
    • 33947593811 scopus 로고    scopus 로고
    • Rethinking enhancement in sport
    • Miah A. Rethinking enhancement in sport. Ann NY Acad Sci 2006; 1093: 301-320.
    • (2006) Ann NY Acad Sci , vol.1093 , pp. 301-320
    • Miah, A.1
  • 54
    • 34548723321 scopus 로고    scopus 로고
    • Potential use of gene transfer in athletic performance enhancement
    • Baoutina A, Alexander IE, Rasko JE, Emslie KR. Potential use of gene transfer in athletic performance enhancement. Mol Ther 2007; 15 1751-1766.
    • (2007) Mol Ther , vol.15 , pp. 1751-1766
    • Baoutina, A.1    Alexander, I.E.2    Rasko, J.E.3    Emslie, K.R.4
  • 56
  • 57
    • 33847421319 scopus 로고    scopus 로고
    • Vascu? endothelial growth factors: Biology and current status of clinical applications in cardiovascular medicine
    • Yla-Herttuala S, Rissanen TT, Vajanto I, Hartikainen J. Vascu? endothelial growth factors: Biology and current status of clinical applications in cardiovascular medicine. J Am Coll Cardiol 2007; 49: 1015-1026.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1015-1026
    • Yla-Herttuala, S.1    Rissanen, T.T.2    Vajanto, I.3    Hartikainen, J.4
  • 58
    • 33745651801 scopus 로고    scopus 로고
    • An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia
    • Xie D, Li Y, Reed EA, Odronic SI, Kontos CD, Annex BH. An engineered vascular endothelial growth factor-activating transcription factor induces therapeutic angiogenesis in ApoE knockout mice with hindlimb ischemia. J Vasc Surg 2006; 44: 166-175.
    • (2006) J Vasc Surg , vol.44 , pp. 166-175
    • Xie, D.1    Li, Y.2    Reed, E.A.3    Odronic, S.I.4    Kontos, C.D.5    Annex, B.H.6
  • 59
    • 34848902043 scopus 로고    scopus 로고
    • Progress and prospects: Gene therapy clinical trials (part 1)
    • Alton E, Ferrari S, Griesenbach U. Progress and prospects: Gene therapy clinical trials (part 1). Gene Therapy 2007; 14: 1439-1447.
    • (2007) Gene Therapy , vol.14 , pp. 1439-1447
    • Alton, E.1    Ferrari, S.2    Griesenbach, U.3
  • 60
    • 33746328957 scopus 로고    scopus 로고
    • Signaling pathways in skeletal muscle remodeling
    • Bassel-Duby R, Olson EN. Signaling pathways in skeletal muscle remodeling. Annu Rev Biochem 2006; 75: 19-37.
    • (2006) Annu Rev Biochem , vol.75 , pp. 19-37
    • Bassel-Duby, R.1    Olson, E.N.2
  • 61
    • 33746253854 scopus 로고    scopus 로고
    • Gene therapy with anabolic growth factors to prevent muscle atrophy
    • Schakman O, Thissen JP. Gene therapy with anabolic growth factors to prevent muscle atrophy. Curr Opin Clin Nutr Metab Care 2006; 9 207-213.
    • (2006) Curr Opin Clin Nutr Metab Care , vol.9 , pp. 207-213
    • Schakman, O.1    Thissen, J.P.2
  • 62
    • 33750172251 scopus 로고    scopus 로고
    • Genetic disorders in the growth hormone - insulin-like growth factor-I axis
    • Walenkamp MJ, Wit JM. Genetic disorders in the growth hormone - insulin-like growth factor-I axis. Horm Res 2006; 66: 221-230.
    • (2006) Horm Res , vol.66 , pp. 221-230
    • Walenkamp, M.J.1    Wit, J.M.2
  • 63
    • 14644435182 scopus 로고    scopus 로고
    • The growth factor myostatin, a key regulator in skeletal muscle growth and homeostasis
    • Matsakas A, Diel P. The growth factor myostatin, a key regulator in skeletal muscle growth and homeostasis. Int J Sports Med 2005; 26: 83-89.
    • (2005) Int J Sports Med , vol.26 , pp. 83-89
    • Matsakas, A.1    Diel, P.2
  • 64
    • 33745854176 scopus 로고    scopus 로고
    • Myostatin regulation of muscle development: Molecular basis, natural mutations, physiopathological aspects
    • Joulia-Ekaza D, Cabello G. Myostatin regulation of muscle development: molecular basis, natural mutations, physiopathological aspects. Exp Cell Res 2006; 312: 2401-2414.
    • (2006) Exp Cell Res , vol.312 , pp. 2401-2414
    • Joulia-Ekaza, D.1    Cabello, G.2
  • 66
    • 14544268116 scopus 로고    scopus 로고
    • Regulatory role of peroxisome proliferator-activated receptor delta (PPAR delta) in muscle metabolism. A new target for metabolic syndrome treatment?
    • Grimaldi PA. Regulatory role of peroxisome proliferator-activated receptor delta (PPAR delta) in muscle metabolism. A new target for metabolic syndrome treatment? Biochimie 2005; 87: 5-8.
    • (2005) Biochimie , vol.87 , pp. 5-8
    • Grimaldi, P.A.1
  • 67
    • 33845674997 scopus 로고    scopus 로고
    • The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle
    • Arany Z, Lebrasseur N, Morris C, Smith E, Yang W, Ma Y et al. The transcriptional coactivator PGC-1beta drives the formation of oxidative type IIX fibers in skeletal muscle. Cell Metab 2007, 5: 35-46.
    • (2007) Cell Metab , vol.5 , pp. 35-46
    • Arany, Z.1    Lebrasseur, N.2    Morris, C.3    Smith, E.4    Yang, W.5    Ma, Y.6
  • 68
    • 34250797341 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-delta polymorphisms are associated with physical performance and plasma lipids the HERITAGE Family Study
    • Hautala AJ, Leon AS, Skinner JS, Rao DC, Bouchard C, Rankinen T. Peroxisome proliferator-activated receptor-delta polymorphisms are associated with physical performance and plasma lipids the HERITAGE Family Study. Am J Physiol Heart Circ Physiol 2007; 292: H2498-H2505.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Hautala, A.J.1    Leon, A.S.2    Skinner, J.S.3    Rao, D.C.4    Bouchard, C.5    Rankinen, T.6
  • 69
    • 33646671717 scopus 로고    scopus 로고
    • Intravenous infusion of an antisense oligonucleotide results in exon skipping in muscle dystrophin mRNA of Duchenne muscular dystrophy
    • Takeshima Y, Yagi M, Wada H, Ishibashi K, Nishiyama A, Kakumoto M et al. Intravenous infusion of an antisense oligonucleotide results in exon skipping in muscle dystrophin mRNA of Duchenne muscular dystrophy. Pediatr Res 2006; 59: 690-694.
    • (2006) Pediatr Res , vol.59 , pp. 690-694
    • Takeshima, Y.1    Yagi, M.2    Wada, H.3    Ishibashi, K.4    Nishiyama, A.5    Kakumoto, M.6
  • 70
    • 33748435917 scopus 로고    scopus 로고
    • Effects of oestrogen on cognition: What have we learned from basic research?
    • Daniel JM. Effects of oestrogen on cognition: What have we learned from basic research? J Neuroendocrinol 2006; 18: 787-795.
    • (2006) J Neuroendocrinol , vol.18 , pp. 787-795
    • Daniel, J.M.1
  • 71
    • 25144507707 scopus 로고    scopus 로고
    • Gene-transfer technology: A preventive neurotherapy to curb obesity, ameliorate metabolic syndrome and extend life expectancy
    • Kalra SP, Kalra PS. Gene-transfer technology: A preventive neurotherapy to curb obesity, ameliorate metabolic syndrome and extend life expectancy. Trends Pharmacol Sci 2005; 26: 488-495.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 488-495
    • Kalra, S.P.1    Kalra, P.S.2
  • 72
    • 33749490524 scopus 로고    scopus 로고
    • Tall girls: The social shaping of a medical therapy
    • Lee JM, Howell JD. Tall girls: The social shaping of a medical therapy. Arch Pediatr Adolesc Med 2006; 160: 1035-1039.
    • (2006) Arch Pediatr Adolesc Med , vol.160 , pp. 1035-1039
    • Lee, J.M.1    Howell, J.D.2
  • 73
    • 26844545020 scopus 로고    scopus 로고
    • Animal models for growth hormone gene therapy
    • Peroni CN, Gout PW, Bartolini P. Animal models for growth hormone gene therapy. Curr Gene Ther 2005; 5: 493-509.
    • (2005) Curr Gene Ther , vol.5 , pp. 493-509
    • Peroni, C.N.1    Gout, P.W.2    Bartolini, P.3
  • 75
    • 33646823588 scopus 로고    scopus 로고
    • The hair follicle and its stem cells as drug delivery targets
    • Hoffman RM. The hair follicle and its stem cells as drug delivery targets. Expert Opin Drug Deliv 2006, 3: 437-443.
    • (2006) Expert Opin Drug Deliv , vol.3 , pp. 437-443
    • Hoffman, R.M.1
  • 76
    • 33645758490 scopus 로고    scopus 로고
    • Hair follicle stem cell-targeted gene transfer and reconstitution system
    • Sugiyama-Nakagiri Y, Akiyama M, Shimizu H. Hair follicle stem cell-targeted gene transfer and reconstitution system. Gene Therapy 2006; 13: 732-737.
    • (2006) Gene Therapy , vol.13 , pp. 732-737
    • Sugiyama-Nakagiri, Y.1    Akiyama, M.2    Shimizu, H.3
  • 77
    • 35848965496 scopus 로고    scopus 로고
    • Progress and prospects: Gene therapy clinical trials (part 2)
    • Alton E, Ferrari S, Griesenbach U. Progress and prospects: Gene therapy clinical trials (part 2). Gene Therapy 2007; 14: 1555-1563.
    • (2007) Gene Therapy , vol.14 , pp. 1555-1563
    • Alton, E.1    Ferrari, S.2    Griesenbach, U.3
  • 78
    • 33845524625 scopus 로고    scopus 로고
    • Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells
    • Mavilio F, Pellegrini G, Ferrari S, Di NF, Di IE, Recchia A et al. Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells. Nat Med 2006, 12: 1397-1402.
    • (2006) Nat Med , vol.12 , pp. 1397-1402
    • Mavilio, F.1    Pellegrini, G.2    Ferrari, S.3    Di NF, D.I.4    Recchia, A.5
  • 79
    • 25144503343 scopus 로고    scopus 로고
    • Antiaging medicine and mild cognitive impairment: Practice and policy issues for geriatrics
    • Whitehouse PJ, Juengst ET. Antiaging medicine and mild cognitive impairment: Practice and policy issues for geriatrics. J Am Geriatr Soc 2005; 53: 1417-1422.
    • (2005) J Am Geriatr Soc , vol.53 , pp. 1417-1422
    • Whitehouse, P.J.1    Juengst, E.T.2
  • 80
    • 33646144461 scopus 로고    scopus 로고
    • Life extension research: An analysis of contemporary biological theories and ethical issues
    • Marshall J. Life extension research: An analysis of contemporary biological theories and ethical issues. Med Health Care Philos 2006; 9: 87-96.
    • (2006) Med Health Care Philos , vol.9 , pp. 87-96
    • Marshall, J.1


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