Cell-cycle protein modifications in the kidney of Mus spretus from Doñana National Park

Environmental Toxicology

Volumn 23, Issue 1, 2008, Pages 44-51

  Leoni, Silvia ^a   Torrice, Alessia ^a   Chiuchiarelli, Giorgia ^a   Bruscalupi, Giovannella ^a   Cristaldi, Mauro ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Aznalcollar mine disaster; Cell cycle proteins; Environmental pollution; Kidney; Wild rodents

Indexed keywords

CELL CYCLE INHIBITORS; MITOGEN ACTIVATED PROTEIN KINASES (MAPK);

BIOLOGICAL SYSTEMS; BIOMARKERS; ECOSYSTEMS; LIVING SYSTEMS STUDIES; TOXIC MATERIALS;

PROTEINS;

BIOCHEMICAL MARKER; BIOLOGICAL MARKER; CELL CYCLE INHIBITOR; CELL CYCLE PROTEIN; CYCLIN A; CYCLIN D1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; CYCLINE; DNA; HEAT SHOCK PROTEIN 70; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN P21; PROTEIN P27; PROTEIN P53; PYRITE; UNCLASSIFIED DRUG;

APOPTOSIS; BIOASSAY; BIOMARKER; CYTOLOGY; ENDOCRINE SYSTEM; GENOTOXICITY; INHIBITION; PROTEIN; RIVER POLLUTION; RODENT;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE S PHASE; CELL DIVISION; CELL GROWTH; CELL PROLIFERATION; DISASTER; DNA DAMAGE; ENZYME ACTIVATION; GENETIC STABILITY; KIDNEY CELL; MINING; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; RIVER ECOSYSTEM; SIGNAL TRANSDUCTION; SPAIN; TISSUE INJURY; WILDLIFE CONSERVATION;

ANIMALS; ANIMALS, WILD; BIOLOGICAL MARKERS; CELL CYCLE PROTEINS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; ENVIRONMENTAL POLLUTANTS; KIDNEY; METALS, HEAVY; MICE; MINING; MURIDAE; RIVERS; SPAIN;

ANDALUCIA; DONANA NATIONAL PARK; EURASIA; EUROPE; GUADIAMAR RIVER; SEVILLA; SOUTHERN EUROPE; SPAIN;

ANIMALIA; MUS SPRETUS; RODENTIA;

EID: 39449089072     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20313     Document Type: Article

References (34)

1. Alzaga R, Mesa A, Ortiz L, Bayona JM. 1999. Characterization of organic compounds in soil and water affected by pyrite tailing spillage. Sci Total Environ 242:167-178.
2. Beck F, Neuhoffer W, Muller E. 2000. Molecular chaperones in the kidney: Distribution, putative roles, and regulation. Am J Physiol Renal Physiol 279:F203-F215.
3. Bomhard EM, Maruhn D, Rinke M. 1999. Time course of chronic oral cadmium nephrotoxicity in Wistar rats: Excretion of urinary enzymes. Drug Chem Toxicol 22:679-703.
4. Bonham RT, Rfine M, Pollok FM, Schelden EA. 2003. Hsp 27, Hsp 70 and metallothionein in MCDK and LLC-PK1 renal epithelial cells: Effect of prolonged exposure to cadmium. Toxicol Appl Pharmacol 191:63-73.
5. Cristaldi M, Ieradi LA, Mascalzoni D, Mattet T, Van Axel Castelli I. 1990. 137Cs determination and mutagenicity tests in wild Mus musculus domesticus before and after the Chernobyl accident. Environ Pollut 64:1-9.
6. Cristaldi M, Chiuchiarelli G, Ieradi LA, Tanzarella C, Cozzi R, Grossi R, Campanella L, Moreno S. Biomonitoring of genetic damage on Algerian mouse (Mus spretus) as a sentinel species in Doñana National Park (1995-2000). In: DelValls, Blasco, editors. Integrated Assessment and Management of the Ecosystems Affected by the Aznalcollar Mining Spill (SW, Spain). IOC/ICAM/UNESCO Technical report (in press).
7. Diamond GL, Zalups RK. 1998. Understanding renal toxicity of heavy metals. Toxicol Pathol 26:92-103.
8. Ding W, Templeton DM. 2000. Activation of parallel mitogen-activated protein kinase cascades and induction of c-fos by cadmium. Toxicol Appl Pharmacol 162:93-99.
9. Festa F, Cristaldi M, Ieradi LA, Moreno S, Cozzi R. 2003. The Comet assay for the detection of DNA damage in Mus spretus from Doñana National Park. Environ Res 91:54-61.
10. Friberg L. 1984. Cadmium and the kidney. Environ Health Perspect 54:1-11.
11. Goyer R. 1989. Mechanisms of lead and cadmium nephrotoxicity. Toxicol Lett 46:153-162.
12. Grimait J, Ferrer M, Macpherson, E. 1999. The mine Tailing accident in Aznalcollar. Sci Total Environ 242:3-11.
13. Hamada T, Sasaguri T, Tanimoto A, Sasaguri Y. 1996. Apoptosis of human kidney 293 cells is promoted by polymerized cadmium-metallothionein. Biochem Biophys Res Commun 219:829-834.
14. Herak-Kramberger CM, Sabolic I. 2001. The integrity of renal cortical brush border and basolateral membrane vesicles is damaged in vitro by nephrotoxic heavy metals. Toxicol 156:139-147.
15. Koizumi T, Shirakura H, Kumagai H, Tatsumoto H, Suzuki KT. 1996. Mechanism of cadmium-induced cytotoxicity in rat hepatocytes: Cadmium-induced active oxigen related permeability changes of the plasma membrane. Toxicology 114:125-134.
16. Ieradi LA, Cristaldi M, Mascalzoni D, Cardarelli E, Grossi R, Campanella L. 1996. Genetic damage in urban mice exposed to traffic pollution. Environ Pollut 92:323-328.
17. Ieradi LA, Moreno S, Bolivar JP, Cappai A, Di Benedetto A, Cristaldi M. 1998. Free-living rodents as bioindicators of genetic risk in natural protected areas. Environ Pollut 102:265-268.
18. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin-phenol reagent. J Biol Chem 193:265-275.
19. Madden EF, Fowler BA. 2000. Mechanisms of nephrotoxicity from metal combinations: A review. Drug Chem Toxicol 23:1-12.
20. Matsuoka M, Wispriyono B, Iryo Y, Igisu H. 2000. Mercury chloride activates c-Jun N-terminal Kinase and induces c-jun expression in LLC-PK1 cell. Toxicol Sci 53:361-368.
21. Morgan DO. 1997. Cyclin-dependent kinases: Engines, clocks and microprocessors. Annu Rev Cell Dev Biol 13:261-291.
22. Nolan CV, Shaikhu ZA. 1992. Lead nephrotoxicity and associated disorders: Biochemical mechanism. Toxicology 73:127-146.
23. Pain DJ, Sanchez A, Meharg AA. 1998. The Doñana ecological disaster: Contamination of a world heritage estuarine marsh ecosystem with acidified pyrite mine waste. Sci Total Environ 222:45-54.
24. Palomo LJ. 1990. Caracteristicas de los deplazamientos del raton moruno, Mus spretus Lataste en cultivos de cana de azucar de la provincia de Malaga. Ecologia (Icona Madrid) 4:185-189.
25. Pourahmad JO, Brien PJ, Jokar F, Daraei B. 2003. Carcinogenic metal induced sites of reactive oxygen species formation in hepatocytes. Toxicol In Vitro 17:803-810.
26. Romero-Ruiz A, Carrascal M, Alhama J, Gomez-Ariza JL, Abian J, Lopez-Barea J. 2006. Utility of proteomics to assess pollutant response of clams from the Donana bank of Guadalquivir Estuary (SW Spain). Proteomics 6:S245-S255.
27. Ruiz-Laguna J, Garcia-Alfonso C, Peinado J, Moreno S, Ieradi LA, Cristaldi M, Lopez-Barea J. 2001. Biochemical biomarkers of pollution in Algerian mouse (Mus spretus) to assess the effect of the Aznalcollar disaster on Doñana Park. Biomarkers 6:146-160.
28. Sherr CJ, Roberts JM. 1999. CDK inhibitors: Positive and negative regulators of G1 phase progression. Genes Dev 13:1501-1512.
29. Shibutani M, Mitsumori K, Niho N, Satoh S, Hiratsuka H, Satoh M, Sumiyoshi M, Nishijima M, Katsuki Y, Suzuki J, Nakagawa J, Ando M. 2000. Assessment of renal toxicity by analysis of regeneration of tubular epithelium in rats given low-dose cadmium chloride or cadmium-polluted rice for 22 months. Arch Toxicol 74:571-577.
30. Stuart J, Shank L, Gunter W. 2000. Cell cycle regulatory proteins in renal disease: Role in hypertrophy, proliferation and apoptosis. Am J Physiol 278:F515-F529.
31. Tanimoto A, Hamada T, Koide O. 1993. Cell death and regeneration of renal proximal tubular cells in rats with subchronic cadmium intoxication. Toxicol Pathol 21:341-352.
32. Tanzarella C, Degrassi F, Cristaldi M, Moreno S, Lascialfari A, Chiuchiarelli G, Ieradi LA. 2001. Genotoxic damage in free-living Algerian mouse (Mus spretus) after the Coto Doñana ecological disaster. Environ Pollut 115:43-48.
33. Victery W, Miller CR, Fowler BA. 1984. Lead accumulation by rat renal brush border membrane vesicles. J Pharmacol Exp Ther 231:589-596.
34. Wilkinson MG, Millar JBA. 2000. Control of eukaryotic cell cycle by MAP kinase signalling pathways. FASEB J 14:2147-2157.