Activation of parallel mitogen-activated protein kinase cascades and induction of c-fos by cadmium

Toxicology and Applied Pharmacology

Volumn 162, Issue 2, 2000, Pages 93-99

  Ding, Wei ^a   Templeton, Douglas M ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

c jun kinase; Erk kinase; Mesangial cell; Metal ions

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CADMIUM; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE ACTIVITY; GENE EXPRESSION; GENE INDUCTION; MALE; MESANGIUM CELL; MITOGENESIS; NONHUMAN; ONCOGENE C FOS; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 0034650886     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1999.8829     Document Type: Article

References (50)

1. Achanzar W. E., Bello-Deocampo D., Webber M. M., Waalkes M. P. Cadmium activates oncogene expression in human prostate epithelial cells. Toxicol. Science 48:1999;355-356
2. Bossy-Wetzel E., Bakiri L., Yaniv M. Induction of apoptosis by the transcription factor c-Jun. EMBO J. 16:1997;1695-1709
3. Chao S.-H., Suzuki Y., Zysk J. R., Cheung W. Y. Activation of calmodulin by various metal cations as a function of ionic radius. Mol. Pharmacol. 26:1984;75-82
4. Cheung W. Y. Calmodulin and its activation by cadmium ion. Ann. NY Acad. Science 522:1988;74-87
5. Chomczynski P., Mackey K. Modification of the TRI Reagent(TM) procedure for isolation of RNA from polysaccharide- and proteoglycan-rich sources. BioTechniques. 19:1995;942-945
6. Coogan T. P., Shiraishi N., Waalkes M. P. Minimal basal activity and lack of metal-induced activation of the metallothionein gene correlates with lobe-specific sensitivity to the carcinogenic effects of cadmium in the rat prostate. Toxicol. Appl. Pharmacol. 132:1995;164-173
7. Curran T., Gordon M. B., Rubino K. L., Sambucetti L. C. Isolation and characterization of the c-fos (rat) cDNA and analysis of post-translational modification in vitro. Oncogene. 2:1987;79-84
8. El Azzouzi B., Tsangaris G. T., Pellegrini O., Manuel Y., Benveniste J., Thomas Y. Cadmium induces apoptosis in a human T cell line. Toxicology. 88:1994;127-139
9. Epner D. E., Herschman H. R. Heavy metals induce expression of the TPA-inducible sequence (TIS) genes. J. Cell. Physiol. 148:1991;68-74
10. Evan G. I., Wyllie A. H., Gilbert C. S., Littlewood T. D., Land H., Brooks M., Waters C. M., Penn L. Z., Hancock D. C. Induction of apoptosis in fibroblasts by c-myc protein. Cell. 69:1992;119-128
11. Flik G., van de Winkel J. G. J., Pärt P., Wendelaar Bonga S. E., Lock R. A. C. Calmodulin-mediated cadmium inhibition of phosphodiesterase activity, in vitro. Arch. Toxicol. 59:1987;353-359
12. Fowler B. A., Goering P. L., Squibb K. S. Mechanism of cadmium-metallothionein-induced nephrotoxicity: Relationship to altered renal calcium metabolism. Experientia. 52:1987;661-668
13. Friberg L. Cadmium and the kidney. Environ. Health Perspect. 54:1984;1-11
14. Ghosh A., Greenberg M. E. Calcium signaling in neurons: Molecular mechanisms and cellular consequences. Science. 268:1995;239-247
15. Gille H., Sharrocks A. D., Shaw P. Phosphorylation of p62TCF by MAP kinase stimulates ternary complex formation at the c-fos promoter. Nature. 358:1992;414-417
16. Gong Z. Improved RNA staining in formaldehyde gels. BioTechniques. 12:1992;74-75
17. Habeebu S. S. M., Liu J., Klaassen C. D. Cadmium-induced apoptosis in mouse liver. Toxicol. Appl. Pharmacol. 149:1998;203-209
18. Hardingham G. E., Chawla S., Johnson C. M., Bading H. Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression. Nature. 385:1997;260-265
19. Hill C. S., Treisman R. Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G proteins and polypeptide growth factors. EMBO J. 14:1995;5037-5047
20. International Agency for Research on Cancer (IARC), 1993, Beryllium, Cadmium, Mercury and Exposures in the Glass Manufacturing Industry. Vol, 58, IARC, Lyon
21. Ishido M., Tohyama C., Suzuki T. c-myc is not involved in cadmium-elicited apoptotic pathway in porcine kidney LLC-PK1 cells. Life Science 63:1998;1195-1204
22. Ishikawa T., Igarashi T., Hata K., Fujita T. c-fos induction by heat, arsenite, and cadmium is mediated by a heat shock element in its promoter. Biochem. Biophys. Res. Commun. 254:1999;566-571
23. Janknecht R., Ernst W. H., Pingoud V., Nordheim A. Activation of ternary complex factor Elk-1 by MAP kinases. EMBO J. 12:1993;5097-5104
24. Jin P., Ringertz N. R. Cadmium induces transcription of proto-oncogenes c-jun and c-myc in rat L6 myoblasts. J. Biol. Chem. 265:1990;14061-14064
25. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685
26. Lohmann R. D., Beyersman D. Effects of zinc and cadmium on apoptotic DNA fragmentation in isolated bovine liver nuclei. Environ. Health Perspect. 102:1994;269-271
27. 1 cells. Kidney Int. 48:1995;383-389
28. Matsuoka M., Igisu H. Activation of c-Jun NH2-terminal kinase (JNK/SAPK) in LLC-PK1 cells by cadmium. Biochem. Biophys. Res. Commun. 251:1998;527-532
29. Misra R. P., Bonni A., Miranti C. K., Rivera V. M., Sheng M., Greenberg M. E. L-type voltage sensitive calcium channel activation stimulates gene expression by a serum response factor-dependent pathway. J. Biol. Chem. 269:1994;25483-25493
30. Morselt A. F. W. Environmental pollutants and diseases. A cell biological approach using chronic cadmium exposure in the animal model as a paradigm case. Toxicology. 70:1991;1-132
31. Ovelgönne J. H., Souren J. M., Wiegant F. C., Van Wijk R. Relationship between cadmium-induced expression of heatshock genes, inhibition of protein synthesis and cell death. Toxicology. 99:1995;19-30
32. Peterson G. L. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem. 83:1977;346-356
33. Preston G. A., Lyon T. T., Yin Y., Lang J. E., Solomon G., Annab L., Srinivasan D. G., Alcorta D. A., Barrett J. C. Induction of apoptosis by c-Fos protein. Mol. Cell. Biol. 16:1996;211-218
34. 2+ depletion. Kidney Int. 41:1992;1237-1244
35. Rivera V. M., Miranti C. K., Misra R. P., Ginty D. D., Chen R.-H., Blenis J., Greenberg M. E. A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity. Mol. Cell. Biol. 13:1993;6260-6273
36. Rosen L. B., Ginty D. D., Greenberg M. E. Calcium regulation of gene expression. Means A. R. Advances in Second Messenger and Phosphoprotein Research. 1995;225-253 Raven Press, New York
37. 2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science. 252:1991;1427-1430
38. Shimada H., Shiao Y. H., Shibata M.-A., Waalkes M. P. Cadmium suppresses apoptosis induced by chromium. J. Toxicol. Environ. Health. 54:1998;159-168
39. Smith J. B., Dwyer S. D., Smith L. Cadmium evokes inositol polyphosphate formation and calcium mobilization. J. Biol. Chem. 264:1989;7115-7118
40. 2+-induced c-myc mRNA accumulation in NRK-49F cells is blocked by the protein kinase inhibitor H7 but not by HA1004, indicating that protein kinase C is a mediator of the response. Toxicology. 81:1993;155-164
41. Templeton D. M. Cadmium uptake by cells of renal origin. J. Biol. Chem. 265:1990;21764-21770
42. Templeton D. M., Wang Z., Miralem T. Cadmium, cell signaling, and oncogene expression. Toxicol. Lett. 95:1998;1-8
43. Treisman R. Ternary complex factors: Growth factors regulated transcriptional activators. Curr. Opin. Genet. Dev. 4:1994;96-101
44. Tsangaris G. T., Tzortzatou-Stathopoulou F. Cadmium induces apoptosis differentially on immune system cell lines. Toxicology. 128:1998;143-150
45. van Delft S., Coffer P., Kreijer W., van Wijk R. c-Fos induction by stress can be mediated by the SRE. Biochem. Biophys. Res. Commun. 197:1993;542-548
46. Wang A., Templeton D. M. Inhibition of mitogenesis and c-fos expression in mesangial cells by heparin and heparan sulfates. Kidney Int. 69:1996;437-448
47. Wang Z., Chin T. A., Templeton D. M. Calcium-independent effects of cadmium on actin assembly in mesangial and vascular smooth muscle cells. Cell Motil. Cytoskeleton. 32:1996;208-222
48. Wang Z., Templeton D. M. Induction of c-fos proto-oncogene in mesangial cells by cadmium. J. Biol. Chem. 273:1998;73-79
49. Whitmarsh A. J., Shore P., Sharrocks A. D., Davis R. J. Integration of MAP kinase signal transduction pathways at the serum response element. Science. 269:1995;403-407
50. Xu C. Y., Johnson J. E., Singh P. K., Jones M. M., Yan H. P., Carter C. E. In vivo studies of cadmium-induced apoptosis in testicular tissue of the rat and its modulation by a chelating agent. Toxicology. 107:1996;1-8