The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-κB inhibition

Oncogene

Volumn 27, Issue 8, 2008, Pages 1122-1134

  Sebens Muerkoster S ^a   Rausch, A V ^a   Isberner, A ^a   Minkenberg, J ^a   Blaszczuk, E ^a   Witt, M ^a   Folsch U R ^a   Schmitz, F ^a,b   Schafer H ^a   Arlt, A ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b Klinikum Hildesheim   (Germany)

Author keywords

Apoptosis; Colon cancer; Early response gene; Gastrin receptor; Loss of function mutation

Indexed keywords

CHOLECYSTOKININ B RECEPTOR; FLUOROURACIL; GASTRIN; GASTRIN 17; HEAT SHOCK PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OMEPRAZOLE; PROTEIN IEX 1; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CELL TYPE; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; EARLY RESPONSE GENE; GENE ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYPERGASTRINEMIA; INHIBITION KINETICS; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT RESPONSE; WILD TYPE; XENOGRAFT;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; FEMALE; GASTRINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; MEMBRANE PROTEINS; MICE; MICE, SCID; MUTATION; NF-KAPPA B; RECEPTOR, CHOLECYSTOKININ B; TRANSCRIPTION FACTOR RELA;

MUS;

EID: 39149137162     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210728     Document Type: Article

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