Intestinal Expression of Mutant and Wild-Type Progastrin Significantly Increases Colon Carcinogenesis in Response to Azoxymethane in Transgenic Mice

Cancer

Volumn 100, Issue 6, 2004, Pages 1311-1323

  Cobb, Stephanie ^a   Wood, Thomas ^b   Ceci, Jeffrey ^a   Varro, Andrea ^c   Velasco, Marco ^d   Singh, Pomila ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d Vel Lab Research   (United States)

Author keywords

Aberrant crypt foci; Adenomas; Carcinomas; Colonic malignancy; Gastrins

Indexed keywords

AZOXYMETHANE; CARCINOGEN; FATTY ACID BINDING PROTEIN; PROGASTRIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RISK; COLON ADENOCARCINOMA; COLON ADENOMA; COLON CARCINOGENESIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMALE; GENDER; HYPERGASTRINEMIA; INTESTINE CRYPT; INTESTINE MUCOSA; MALE; MOUSE; NONHUMAN; PRECANCER; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN TARGETING; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; AZOXYMETHANE; CARCINOGENS; COLONIC NEOPLASMS; FEMALE; GASTRINS; HUMANS; MALE; MICE; MICE, TRANSGENIC; POLYMERASE CHAIN REACTION; PRECANCEROUS CONDITIONS; PROTEIN PRECURSORS; RADIOIMMUNOASSAY;

EID: 1542344358     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.20094     Document Type: Article

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