Oxidative injury induces selective rather than global inhibition of proteasomal activity

Journal of Molecular and Cellular Cardiology

Volumn 44, Issue 2, 2008, Pages 419-428

  Gurusamy, Narasimman ^a   Goswami, Shyamal ^a   Malik, Gautam ^a   Das, Dipak K ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

Author keywords

I B; Ischemia reperfusion; Myoblast; Nrf2; Proteasome

Indexed keywords

EPOXOMICIN; GLUCOSE REGULATED PROTEIN 78; I KAPPA B; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LACTACYSTIN; PROTEASOME; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; IMMUNOHISTOCHEMISTRY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT; WESTERN BLOTTING;

ACETYLCYSTEINE; ANIMALS; CELL LINE; CELL NUCLEUS; ENDOPLASMIC RETICULUM; I-KAPPA B PROTEINS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 39149124870     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2007.10.005     Document Type: Article

References (41)

1. Nabel E.G. Cardiovascular disease. N Engl J Med 349 (2003) 60-72
2. Bolli R., Becker L., Gross G., Mentzer Jr. R., Balshaw D., and Lathrop D.A. Myocardial protection at a crossroads: the need for translation into clinical therapy. Circ Res 95 (2004) 125-134
3. Kubasiak L.A., Hernandez O.M., Bishopric N.H., and Webster K.A. Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3. Proc Natl Acad Sci U S A 99 (2002) 12825-12830
4. Chen Q., and Lesnefsky E.J. Depletion of cardiolipin and cytochrome c during ischemia increases hydrogen peroxide production from the electron transport chain. Free Radic Biol Med 40 (2006) 976-982
5. Petrosillo G., Di Venosa N., Ruggiero F.M., Pistolese M., D'Agostino D., Tiravanti E., et al. Mitochondrial dysfunction associated with cardiac ischemia/reperfusion can be attenuated by oxygen tension control. Role of oxygen-free radicals and cardiolipin. Biochim Biophys Acta 1710 (2005) 78-86
6. Mason R.P. Using anti-5,5-dimethyl-1-pyrroline N-oxide (anti-DMPO) to detect protein radicals in time and space with immuno-spin trapping. Free Radic Biol Med 36 (2004) 1214-1223
7. Matsushima S., Ide T., Yamato M., Matsusaka H., Hattori F., Ikeuchi M., et al. Overexpression of mitochondrial peroxiredoxin-3 prevents left ventricular remodeling and failure after myocardial infarction in mice. Circulation 113 (2006) 1779-1786
8. Asimakis G.K., Lick S., and Patterson C. Postischemic recovery of contractile function is impaired in SOD2(+/-) but not SOD1(+/-) mouse hearts. Circulation 105 (2002) 981-986
9. Das D.K., and Maulik N. Preconditioning potentiates redox signaling and converts death signal into survival signal. Arch Biochem Biophys 420 (2003) 305-311
10. Pimentel D.R., Amin J.K., Xiao L., Miller T., Viereck J., Oliver-Krasinski J., et al. Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes. Circ Res 89 (2001) 453-460
11. Gupta M.K., Neelakantan T.V., Sanghamitra M., Tyagi R.K., Dinda A., and Maulik S. An assessment of the role of reactive oxygen species and redox signaling in norepinephrine-induced apoptosis and hypertrophy of H9c2 cardiac myoblasts. Antioxid Redox Signal 8 (2006) 1081-1093
12. Takano H., Zou Y., Hasegawa H., Akazawa H., Nagai T., and Komuro I. Oxidative stress-induced signal transduction pathways in cardiac myocytes: involvement of ROS in heart diseases. Antioxid Redox Signal 5 (2003) 789-794
13. Kuster G.M., Siwik D.A., Pimentel D.R., and Colucci W.S. Role of reversible, thioredoxin-sensitive oxidative protein modifications in cardiac myocytes. Antioxid Redox Signal 8 (2006) 2153-2159
14. Jung T., Bader N., and Grune T. Oxidized proteins: intracellular distribution and recognition by the proteasome. Arch Biochem Biophys 462 (2007) 231-237
15. Powell S.R. The ubiquitin-proteasome system in cardiac physiology and pathology. Am J Physiol Heart Circ Physiol 291 (2006) H1-H19
16. Powell S.R., Wang P., Katzeff H., Shringarpure R., Teoh C., Khaliulin I., et al. Oxidized and ubiquitinated proteins may predict recovery of postischemic cardiac function: essential role of the proteasome. Antioxid Redox Signal 7 (2005) 538-546
17. Kodadek T., Sikder D., and Nalley K. Keeping transcriptional activators under control. Cell 127 (2006) 261-264
18. Ishii T., Sakurai T., Usami H., and Uchida K. Oxidative modification of proteasome: identification of an oxidation-sensitive subunit in 26 S proteasome. Biochemistry 44 (2005) 13893-13901
19. Das S., Powell S.R., Wang P., Divald A., Nesaretnam K., Tosaki A., et al. Cardioprotection with palm tocotrienol: antioxidant activity of tocotrienol is linked with its ability to stabilize proteasomes. Am J Physiol Heart Circ Physiol 289 (2005) H361-H367
20. Ye Y. The role of the ubiquitin-proteasome system in ER quality control. Essays Biochem 41 (2005) 99-112
21. Szegezdi E., Duffy A., O'Mahoney M.E., Logue S.E., Mylotte L.A., O'Brien T., et al. ER stress contributes to ischemia-induced cardiomyocyte apoptosis. Biochem Biophys Res Commun 349 (2006) 1406-1411
22. Martindale J.J., Fernandez R., Thuerauf D., Whittaker R., Gude N., Sussman M.A., et al. Endoplasmic reticulum stress gene induction and protection from ischemia/reperfusion injury in the hearts of transgenic mice with a tamoxifen-regulated form of ATF6. Circ Res 98 (2006) 1186-1193
23. Hall G., Hasday J.D., and Rogers T.B. Regulating the regulator: NF-kappaB signaling in heart. J Mol Cell Cardiol 41 (2006) 580-591
24. Schooley K., Zhu P., Dower S.K., and Qwarnstrom E.E. Regulation of nuclear translocation of nuclear factor-kappaB relA: evidence for complex dynamics at the single-cell level. Biochem J 369 (2003) 331-339
25. Calvaruso G., Giuliano M., Portanova P., De Blasio A., Vento R., and Tesoriere G. Bortezomib induces in HepG2 cells IkappaBalpha degradation mediated by caspase-8. Mol Cell Biochem 287 (2006) 13-19
26. McCormick J., Barry S.P., Sivarajah A., Stefanutti G., Townsend P.A., Lawrence K.M., et al. Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury. FASEB J 20 (2006) 2115-2117
27. Purdom-Dickinson S.E., Lin Y., Dedek M., Morrissy S., Johnson J., and Chen Q.M. Induction of antioxidant and detoxification response by oxidants in cardiomyocytes: evidence from gene expression profiling and activation of Nrf2 transcription factor. J Mol Cell Cardiol 42 (2007) 159-176
28. Kobayashi A., Kang M.I., Watai Y., Tong K.I., Shibata T., Uchida K., et al. Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap1. Mol Cell Biol 26 (2006) 221-229
29. Zhang D.D., Lo S.C., Sun Z., Habib G.M., Lieberman M.W., and Hannink M. Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway. J Biol Chem 280 (2005) 30091-30099
30. Kisselev A.F., Callard A., and Goldberg A.L. Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate. J Biol Chem 281 (2006) 8582-8590
31. Myung J., Kim K.B., Lindsten K., Dantuma N.P., and Crews C.M. Lack of proteasome active site allostery as revealed by subunit-specific inhibitors. Mol Cell 7 (2001) 411-420
32. Meng L., Mohan R., Kwok B.H., Elofsson M., Sin N., and Crews C.M. Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. Proc Natl Acad Sci U S A 96 (1999) 10403-10408
33. Ostrowska H., Wojcik C., Wilk S., Omura S., Kozlowski L., Stoklosa T., et al. Separation of cathepsin A-like enzyme and the proteasome: evidence that lactacystin/beta-lactone is not a specific inhibitor of the proteasome. Int J Biochem Cell Biol 32 (2000) 747-757
34. Geier E., Pfeifer G., Wilm M., Lucchiari-Hartz M., Baumeister W., Eichmann K., et al. A giant protease with potential to substitute for some functions of the proteasome. Science 283 (1999) 978-981
35. Scheidereit C. IkappaB kinase complexes: gateways to NF-kappaB activation and transcription. Oncogene 25 (2006) 6685-6705
36. Maulik N., Goswami S., Galang N., and Das D.K. Differential regulation of Bcl-2, AP-1 and NF-kappaB on cardiomyocyte apoptosis during myocardial ischemic stress adaptation. FEBS Lett 443 (1999) 331-336
37. Zmijewski J.W., Zhao X., Xu Z., and Abraham E. Exposure to hydrogen peroxide diminishes NF-{kappa}B activation, I{kappa}B-{alpha} degradation, and proteasome activity in neutrophils. Am J Physiol Cell Physiol 293 (2007) C255-C266
38. Alvarez-Castelao B., and Castano J.G. Mechanism of direct degradation of IkappaBalpha by 20S proteasome. FEBS Lett 579 (2005) 4797-4802
39. O'Connor S., Markovina S., and Miyamoto S. Evidence for a phosphorylation-independent role for Ser 32 and 36 in proteasome inhibitor-resistant (PIR) IkappaBalpha degradation in B cells. Exp Cell Res 307 (2005) 15-25
40. Rathore N., Matta H., and Chaudhary P.M. An evolutionary conserved pathway of nuclear factor-kappaB activation involving caspase-mediated cleavage and N-end rule pathway-mediated degradation of IkappaBalpha. J Biol Chem 279 (2004) 39358-39365
41. Tergaonkar V., Bottero V., Ikawa M., Li Q., and Verma I.M. IkappaB kinase-independent IkappaBalpha degradation pathway: functional NF-kappaB activity and implications for cancer therapy. Mol Cell Biol 23 (2003) 8070-8083