Mechanisms of the negative inotropic effects of sphingosine-1-phosphate on adult mouse ventricular myocytes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 294, Issue 2, 2008, Pages

  Landeen, Lee K ^a   Dederko, Dorothy A ^a   Kondo, Colleen S ^b   Hu, Betty S ^a   Aroonsakool, Nakon ^a   Haga, Jason H ^a   Giles, Wayne R ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Acetylcholine sensitive potassium; Calcium; Cell shortening; Contraction; Inhibitory G protein; Myocyte

Indexed keywords

5 (4 PHENYL 5 TRIFLUOROMETHYL 2 THIENYL) 3 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 OXADIAZOLE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; RECEPTOR BLOCKING AGENT; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; UNCLASSIFIED DRUG; VPC 23019;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL STIMULATION; CONTROLLED STUDY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; INOTROPISM; MATHEMATICAL MODEL; MOUSE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL;

ACTION POTENTIALS; ANIMALS; CALCIUM CHANNELS, L-TYPE; DEPRESSION, CHEMICAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HEART VENTRICLES; LYSOPHOSPHOLIPIDS; MICE; MICE, INBRED C57BL; MODELS, STATISTICAL; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LYSOSPHINGOLIPID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 39149091725     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00316.2007     Document Type: Article

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