Synthesis, metal ion binding, and biological evaluation of new anticancer 2-(2′-hydroxyphenyl)benzoxazole analogs of UK-1

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 4, 2008, Pages 1775-1783

  McKee, Mireya L ^a   Kerwin, Sean M ^a  

^a The University of Texas at Austin   (United States)

Author keywords

Antibacterial; Cancer cell cytotoxicity; DNA binding; Metal ion binding

Indexed keywords

2 (2' HYDROXYPHENYL)BENZOXAZOLE; 2 (2' HYDROXYPHENYL)BENZOXAZOLE 4 CARBOXYLIC ACID (6 HYDROXYHEXYL)AMIDE; 2 (2' HYDROXYPHENYL)BENZOXAZOLE 4 CARBOXYLIC ACID 2 [2 [2 (2 HYDROXY ETHOXY) ETHOXYL] ETHOXY] ETHYL ESTER; 2 (2' HYDROXYPHENYL)BENZOXAZOLE 4 CARBOXYLIC ACID [2 (2' HYDROXY ETHOXY)ETHYL]AMIDE; 2 (2' HYDROXYPHENYL)BENZOXAZOLE 4 CARBOXYLIC ACID BUTYLAMIDE; 2 (2' HYDROXYPHENYL)BENZOXAZOLE 4 CARBOXYLIC ACID ETHYL ESTER; 2 (2' HYDROXYPHENYL)BENZOXAZOLE 4 CARBOXYLIC ACID METHYLAMIDE; 4 CARBOMETHOXY 2 (2' HYDROXYPHENYL)BENZOXAZOLE; ANTINEOPLASTIC AGENT; BENZOXAZOLE DERIVATIVE; COPPER; MAGNESIUM; UK 1; UNCLASSIFIED DRUG; ZINC;

ANALYTIC METHOD; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DNA BINDING; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN CELL; METAL BINDING; PHARMACOPHORE; SOLUBILITY; TITRIMETRY;

ANTINEOPLASTIC AGENTS; BENZOXAZOLES; BIOLOGICAL PRODUCTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; COPPER; FEMALE; HUMANS; LUNG NEOPLASMS; MAGNESIUM; METALS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 39049159714     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.11.019     Document Type: Article

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