Mg2+-mediated binding of 6-Substituted quinolones to DNA: Relevance to biological activity

Bioorganic and Medicinal Chemistry

Volumn 6, Issue 9, 1998, Pages 1555-1561

  Sissi, Claudia ^a   Andreolli, Magda ^a   Cecchetti, Violetta ^b   Fravolini, Arnaldo ^b   Gatto, Barbara ^a   Palumbo, Manlio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

Author keywords

DNA binding; DNA gyrase; Magnesium; Quinolones; Single stranded DNA

Indexed keywords

CIPROFLOXACIN; DOUBLE STRANDED DNA; MAGNESIUM; QUINOLONE DERIVATIVE; SINGLE STRANDED DNA;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; DNA DRUG COMPLEX; DRUG ACTIVITY; DRUG DNA BINDING;

BINDING SITES; DNA, SINGLE-STRANDED; FLUOROMETRY; MAGNESIUM; QUINOLONES;

EID: 0032168652     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00086-8     Document Type: Article

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