The novel bis(Benzoxazole) cytotoxic natural product UK-1 is a magnesium ion-dependent DNA binding agent and inhibitor of human topoisomerase II

Bioorganic Chemistry

Volumn 27, Issue 4, 1999, Pages 326-337

  Reynolds, Michael B ^a   Deluca, Mark R ^a   Kerwin, Sean M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOXAZINE DERIVATIVE; BENZOXAZOLE DERIVATIVE; DNA TOPOISOMERASE INHIBITOR; MAGNESIUM ION; NATURAL PRODUCT; POTASSIUM ION; UK 1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL INTERACTION; CYTOTOXICITY; DNA BINDING; DRUG ACTIVITY; DRUG ISOLATION; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; STOICHIOMETRY;

STREPTOMYCES SP.;

EID: 0032875978     PISSN: 00452068     EISSN: None     Source Type: Journal    
DOI: 10.1006/bioo.1999.1138     Document Type: Article

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