Hypothermia suppresses excitatory synaptic transmission and neuronal death induced by experimental ischemia in spinal ventral horn neurons

Spine

Volumn 32, Issue 25, 2007, Pages

  Nishi, Hideto ^a   Nakatsuka, Terumasa ^b   Takeda, Daisuke ^a   Miyazaki, Nobuyuki ^a   Sakanaka, Junya ^a   Yamada, Hiroshi ^a   Yoshida, Munehito ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b SAGA UNIVERSITY   (Japan)

Author keywords

Cell death; Electrophysiology; Hypothermia; Ischemia; Spinal motoneurons

Indexed keywords

GLUCOSE; GLUTAMATE RECEPTOR ANTAGONIST; OXYGEN; 2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMINO ACID RECEPTOR BLOCKING AGENT; GLUTAMATE RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CEREBROSPINAL FLUID; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; HYPOTHERMIA; ISCHEMIA; LATENT PERIOD; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SPINAL CORD; SPINAL CORD INJURY; SPINAL CORD VENTRAL HORN; SYNAPTIC POTENTIAL; SYNAPTIC TRANSMISSION; TEMPERATURE; WHOLE CELL; ANIMAL; ANTERIOR HORN CELL; CELL HYPOXIA; CRYOANESTHESIA; DRUG EFFECT; IN VITRO STUDY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; REACTION TIME; SPINAL CORD ISCHEMIA; SPRAGUE DAWLEY RAT; TIME;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; ANTERIOR HORN CELLS; CELL HYPOXIA; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GLUCOSE; HYPOTHERMIA, INDUCED; OXYGEN; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, GLUTAMATE; SPINAL CORD ISCHEMIA; SYNAPTIC TRANSMISSION; TEMPERATURE; TIME FACTORS;

EID: 39049084392     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e31815b654b     Document Type: Article

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