The temperature sensitivity of miniature endplate currents is mostly governed by channel gating: Evidence from optimized recordings and Monte Carlo simulations

Biophysical Journal

Volumn 77, Issue 2, 1999, Pages 1177-1187

  Stiles, Joel R ^a   Kovyazina, Irina V ^a,b   Salpeter, Edwin E ^a   Salpeter, Miriam M ^a  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b KAZAN INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; COMPUTER SIMULATION; INTERCOSTAL MUSCLE; LIZARD; MINIATURE ENDPLATE POTENTIAL; NEUROMUSCULAR TRANSMISSION; NONHUMAN; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVITY; VOLTAGE CLAMP;

ANIMALIA; ANOLIS CAROLINENSIS; ARRHENIUS; CAROLINENSIS; MUS; SQUAMATA;

EID: 0032799789     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(99)76969-9     Document Type: Article

References (41)

1. Adams, B. A. 1989. Temperature and synaptic efficacy in frog skeletal muscle. J. Physiol. (Lond). 408:443-455.
2. Anderson, C. R., and C. F. Stevens. 1973. Voltage clamp analysis of acetylcholine produced end-plate current fluctuations at frog neuromus-cular junction. J. Physiol. (Lond) 235:655-691.
3. Anglister, L., J. R. Stiles, and M. M. Salpeter. 1994. Acetylcholinesterase density and turnover number at frog neuromuscular junctions, with modeling of their role in synaptic function. Neuron. 12:783-794.
4. Barrow, G. M. 1981. Physical Chemistry for the Life Sciences. McGraw-Hill, New York.
5. Bartol, T. M., Jr. 1991. A study of miniature endplate current generation at the vertebrate neuromuscular junction using electrophysiology and Monte Carlo simulation. Ph.D. thesis, Cornell University, Ithaca, New York.
6. Bartol, T. M., B. R. Land, E. E. Salpeter, and M. M. Salpeter. 1991. Monte Carlo simulation of miniature endplate current generation in the vertebrate neuromuscular junction. Biophys. J. 59:1290-1307.
7. Colquhoun, D., and B. Sakmann. 1985. Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate. J. Physiol. (Lond.). 369:501-557.
8. Dilger, J. P., R. S. Brett, D. M. Poppers, and Y. Liu. 1991. The temperature dependence of some kinetic and conductance properties of acetylcholine receptor channels. Biochim. Biophys. Acta. 1063:253-258.
9. Dionne, V. E., and R. L. Parsons. 1981. Characteristics of the acetylcholine operated channel at twitch and slow fiber neuromuscular junctions of the garter snake. J. Physiol. (Lond.). 310:145-158.
10. Dwyer, T. M. 1981. The rising phase of the miniature endplate current at the frog neuromuscular junction. Biochim. Biophys. Acta. 646:51-60.
11. Engel, A. G. 1987. The molecular biology of end-plate diseases. In The Vertebrate Neuromuscular Junction. M. M. Salpeter, editor. Alan R. Liss, New York. 361-424.
12. Finkel, A. S. 1985. Useful circuits for voltage clamping with microelectrodes. In Voltage and Patch Clamping with Microelectrodes. T. G. Smith, Jr., H. Lecar, S. J. Redman, and P. W. Gage, editors. Williams and Wilkins, Baltimore. 9-24.
13. Fishbach, G. D., and Y, Lass. 1978. A transition temperature for acetylcholine channel conductance in chick myoballs. J Physiol. 280: 527-536.
14. Froede, H. C., and I. B. Wilson. 1971. Acetylcholinesterase. In The Enzymes, 3rd ed., Vol. 5. P. D. Boyer, editor. Academic Press, New York. 87-114.
15. Gage, P. W., and R. N. McBurney. 1975. Effects of membrane potential, temperature and neostigmine on the conductance change caused by a quantum of acetylcholine at the toad neuromuscular junction. J. Physiol. (Lond.). 244:385-407.
16. Harper, A. A., J. R. Shelton, and P. W. Watt. 1989. The temperature dependence of the time course of growth and decay of miniature end-plate currents in carp extraocular muscle following thermal acclimation. J. Exp. Biol. 147:237-248.
17. Head, S. D. 1983. Temperature and end-plate currents in rat diaphragm. J. Physiol. (Lond.). 334:441-459.
18. Hoffman, H. M., and V. E. Dionne. 1983. Temperature dependence of ion channel permeation at the endplate channel. J. Gen. Physiol. 81: 687-703.
19. Katz, B., and R. Miledi. 1973. The binding of acetylcholine to receptors and its removal from the synaptic cleft, J. Physiol. (Lond.). 231: 549-574.
20. Kordas, M. 1972. An attempt at an analysis of the factors determining the time course of the end-plate current. II. Temperature. J. Physiol. (Lond.). 224:333-348.
21. Land, B. R., E. E. Salpeter, and M. M. Salpeter. 1980. Acetylcholine receptor site density affects the rising phase of miniature endplate currents. Proc. Natl. Acad. Sci. USA. 77:3736-3740.
22. Land, B. R., E. E. Salpeter, and M. M. Salpeter. 1981. Kinetic parameters for acetylcholine interaction in intact neuromuscular junction. Proc. Natl. Acad. Sci. USA. 78:7200-7204.
23. Land, B. R., W. V. Harris, E. E. Salpeter, and M. M. Salpeter. 1984. Diffusion and binding constants for acetylcholine derived from the falling phase of miniature endplate currents. Proc. Natl. Acad. Sci. USA. 81:1594-1598.
24. Magleby, K. L., and C. F. Stevens. 1972a. The effect of voltage on the time course of end-plate currents. J. Physiol. (Lond.). 223:151-171.
25. Magleby, K. L., and C. F. Stevens. 1972b. A quantitative description of end-plate currents. J. Physiol. (Lond.). 223:173-197.
26. Matthews-Bellinger, J., and M. M. Salpeter. 1978. Distribution of acetylcholine receptors at frog neuromuscular junctions with a discussion of some physiological implications. J. Physiol. (Lond.). 279:197-213.
27. Robertson, B., and K. T. Warm. 1984. The effect of temperature on the growth and decay times of miniature end-plate currents in the mouse diaphragm. Brain Res. 294:346-349.
28. Rosenberry, T. L. 1975. Acetylcholinesterase. Adv. Enzymol. 43:103-208.
29. Sachs, F., and H. Lecar. 1977. Acetylcholine-induced current fluctuations in tissue-cultured muscle cells under voltage clamp. Biophys. J. 17: 129-143.
30. Salpeter, M. M. 1987. Vertebrate neuromuscular junctions: general morphology, molecular organization, and functional consequences. In The Vertebrate Neuromuscular Junction. M. M. Salpeter, editor. Alan R. Liss, New York. 1-54.
31. Salpeter, M. M., C. D. Smith, and J. A. Matthews-Bellinger. 1984. Acetylcholine receptor at neuromuscular junctions by EM autoradiography using mask analysis and linear sources. J. Electron Microsc. Tech. 1:63-81.
32. Schultz, S. G. 1980. Basic Principles of Membrane Transport. Cambridge University Press, New York.
33. Spruce, A. E., L. J. Breckenridge, A. K. Lee, and W. Aimers. 1990. Properties of the fusion pore that forms during exocytosis of a mast cell secretory granule. Neuron. 4:643-654.
34. Stiles, J. R., T. M. Bartol, H. L. Fernandez, E. E. Salpeter, and M. M. Salpeter. 1992. Neuromuscular communication: inferences from computer simulations of miniature endplate currents. Soc. Neurosci. Abst. 18:270.
35. Stiles, J. R., D. Van Helden, T. M. Bartol, Jr., E. E. Salpeter, and M. M. Salpeter. 1996. Miniature endplate current rise times <100 μs from improved dual recordings can be modeled with passive acetylcholine diffusion from a synaptic vesicle. Proc. Natl. Acad. Sci. USA. 93: 5747-5752.
36. Stiles, J. R., T. M. Bartol, Jr., E. E. Salpeter, and M. M. Salpeter. 1998a. Monte Carlo simulation of neurotransmitter release using MCell, a general simulator of cellular physiological processes. In Computational Neuroscience. J. Bower, editor. Plenum Press, New York. 279-284.
37. Stiles, J. R., I. Kovyazina, W. Van der Kloot, and M. M. Salpeter. 1998b. Optimized recordings and physiological implications of rapid (∼ 100 μs) miniature endplate current rise times. Soc. Neurosci. Abst. 24:826.
38. Tanzi, F., and E. D'Angelo. 1995. Miniature endplate current kinetics at the mouse neuromuscular junction: effects of temperature and medium viscosity. Eur. J. Neurosci. 7:1926-1933.
39. Tiiska, A. J., and K. Y. H. Lagerspetz. 1994. Thermal acclimation, neuromuscular synaptic delay and miniature end-plate current decay in the frog Rana temporaria. J. Exp. Biol. 187:131-142.
40. Van der Kloot, W. 1995. The rise times of miniature endplate currents suggest that acetylcholine may be released over a period of time. Biophys. J. 69:148-154.
41. Zanello, L. P., E. Aztiria, S. Antollini, and F. J. Barrantes. 1996. Nicotinic acetylcholine receptor channels are influenced by the physical state of their membrane environment. Biophys. J. 70:2155-2164.