-
1
-
-
0033824123
-
Obesity and cardiovascular disease. Pathogenetic role of the metabolic syndrome and therapeutic implications
-
Abate N. Obesity and cardiovascular disease. Pathogenetic role of the metabolic syndrome and therapeutic implications. J Diabetes Complications 14: 154-174, 2000.
-
(2000)
J Diabetes Complications
, vol.14
, pp. 154-174
-
-
Abate, N.1
-
2
-
-
0011895713
-
Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E
-
Basu SK, Brown MS, Ho YK, Havel RJ, Goldstein JL. Mouse macrophages synthesize and secrete a protein resembling apolipoprotein E. Proc Natl Acad Sci USA 78: 7545-7549, 1981.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 7545-7549
-
-
Basu, S.K.1
Brown, M.S.2
Ho, Y.K.3
Havel, R.J.4
Goldstein, J.L.5
-
3
-
-
0028883354
-
Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice
-
Bellosta S, Mahley RW, Sanan DA, Murata J, Newland DL, Taylor JM, Pitas RE. Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice. J Clin Invest 96: 2170-2179, 1995.
-
(1995)
J Clin Invest
, vol.96
, pp. 2170-2179
-
-
Bellosta, S.1
Mahley, R.W.2
Sanan, D.A.3
Murata, J.4
Newland, D.L.5
Taylor, J.M.6
Pitas, R.E.7
-
4
-
-
0029081525
-
Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation
-
Boisvert WA, Spangerberg J, Curtiss LK. Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation. J Clin Invest 96: 1118-1124, 1995.
-
(1995)
J Clin Invest
, vol.96
, pp. 1118-1124
-
-
Boisvert, W.A.1
Spangerberg, J.2
Curtiss, L.K.3
-
5
-
-
0042734439
-
VLDL induces adipocyte differentiation in ApoE-dependent manner
-
Chiba T, Nakazawa T, Yui K, Kaneko E, Shimokado K. VLDL induces adipocyte differentiation in ApoE-dependent manner. Arterioscler Thromb Vasc Biol 23: 1423-1429, 2003.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 1423-1429
-
-
Chiba, T.1
Nakazawa, T.2
Yui, K.3
Kaneko, E.4
Shimokado, K.5
-
6
-
-
35348965856
-
Obesity causes very low density lipoprotein clearance defects in low-density lipoprotein receptor-deficient mice
-
Coenen KR, Gruen ML, Hasty AH. Obesity causes very low density lipoprotein clearance defects in low-density lipoprotein receptor-deficient mice. J Nutr Biochem 18: 727-735, 2007.
-
(2007)
J Nutr Biochem
, vol.18
, pp. 727-735
-
-
Coenen, K.R.1
Gruen, M.L.2
Hasty, A.H.3
-
7
-
-
0036793431
-
Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice
-
Fazio S, Babaev VR, Burleigh ME, Major AS, Hasty AH, Linton MF. Physiological expression of macrophage apoE in the artery wall reduces atherosclerosis in severely hyperlipidemic mice. J Lipid Res 43: 1602-1609, 2002.
-
(2002)
J Lipid Res
, vol.43
, pp. 1602-1609
-
-
Fazio, S.1
Babaev, V.R.2
Burleigh, M.E.3
Major, A.S.4
Hasty, A.H.5
Linton, M.F.6
-
8
-
-
33847055528
-
Involvement of apolipoprotein e in excess fat accumulation and insulin resistance
-
Gao J, Katagiri H, Ishigaki Y, Yamada T, Ogihara T, Imai J, Uno K, Hasegawa Y, Kanzaki M, Yamamoto TT, Ishibashi S, Oka Y. Involvement of apolipoprotein e in excess fat accumulation and insulin resistance. Diabetes 56: 24-33, 2007.
-
(2007)
Diabetes
, vol.56
, pp. 24-33
-
-
Gao, J.1
Katagiri, H.2
Ishigaki, Y.3
Yamada, T.4
Ogihara, T.5
Imai, J.6
Uno, K.7
Hasegawa, Y.8
Kanzaki, M.9
Yamamoto, T.T.10
Ishibashi, S.11
Oka, Y.12
-
9
-
-
0035936802
-
Atherosclerosis: The road ahead
-
Glass CK, Witztum JL. Atherosclerosis: the road ahead. Cell 104: 503-516, 2001.
-
(2001)
Cell
, vol.104
, pp. 503-516
-
-
Glass, C.K.1
Witztum, J.L.2
-
10
-
-
24344483109
-
Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I
-
Gruen ML, Plummer MR, Zhang W, Posey KA, Linton MF, Fazio S, Hasty AH. Persistence of high density lipoprotein particles in obese mice lacking apolipoprotein A-I. J Lipid Res 46: 2007-2014, 2005.
-
(2005)
J Lipid Res
, vol.46
, pp. 2007-2014
-
-
Gruen, M.L.1
Plummer, M.R.2
Zhang, W.3
Posey, K.A.4
Linton, M.F.5
Fazio, S.6
Hasty, A.H.7
-
11
-
-
33645883532
-
Plasma insulin levels predict atherosclerotic lesion burden in obese hyperlipidemic mice
-
Gruen ML, Saraswathi V, Nuotio-Antar AM, Plummer MR, Coenen KR, Hasty AH. Plasma insulin levels predict atherosclerotic lesion burden in obese hyperlipidemic mice. Atherosclerosis 186: 54-64, 2006.
-
(2006)
Atherosclerosis
, vol.186
, pp. 54-64
-
-
Gruen, M.L.1
Saraswathi, V.2
Nuotio-Antar, A.M.3
Plummer, M.R.4
Coenen, K.R.5
Hasty, A.H.6
-
12
-
-
0037062657
-
Obesity, metabolic syndrome, and coronary atherosclerosis
-
Grundy SM. Obesity, metabolic syndrome, and coronary atherosclerosis. Circulation 105: 2696-2698, 2002.
-
(2002)
Circulation
, vol.105
, pp. 2696-2698
-
-
Grundy, S.M.1
-
13
-
-
0036151865
-
Acute regression of advanced and retardation of early aortic atheroma in immunocompetent apolipoprotein-E (apoE) deficient mice by administration of a second generation [E1(-), E3(-), polymerase(-)] adenovirus vector expressing human apoE
-
Harris JD, Graham IR, Schepelmann S, Stannard AK, Roberts ML, Hodges BL, Hill V, Amalfitano A, Hassall DG, Owen JS, Dickson G. Acute regression of advanced and retardation of early aortic atheroma in immunocompetent apolipoprotein-E (apoE) deficient mice by administration of a second generation [E1(-), E3(-), polymerase(-)] adenovirus vector expressing human apoE. Hum Mol Genet 11: 43-58, 2002.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 43-58
-
-
Harris, J.D.1
Graham, I.R.2
Schepelmann, S.3
Stannard, A.K.4
Roberts, M.L.5
Hodges, B.L.6
Hill, V.7
Amalfitano, A.8
Hassall, D.G.9
Owen, J.S.10
Dickson, G.11
-
14
-
-
0035813206
-
Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice packing both leptin and the low density lipoprotein receptor
-
Hasty A, Shimano H, Osuga J, Namatame I, Takahashi A, Yahagi N, Perrey S, Iizuka Y, Tamura Y, Amemiya-Kudo M, Yoshikawa T, Okazaki H, Ohashi K, Harada K, Matsuzaka T, Sone H, Gotoda T, Nagai R, Ishibashi S, Yamada N. Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice packing both leptin and the low density lipoprotein receptor. J Biol Chem 276: 37402-37408, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 37402-37408
-
-
Hasty, A.1
Shimano, H.2
Osuga, J.3
Namatame, I.4
Takahashi, A.5
Yahagi, N.6
Perrey, S.7
Iizuka, Y.8
Tamura, Y.9
Amemiya-Kudo, M.10
Yoshikawa, T.11
Okazaki, H.12
Ohashi, K.13
Harada, K.14
Matsuzaka, T.15
Sone, H.16
Gotoda, T.17
Nagai, R.18
Ishibashi, S.19
Yamada, N.20
more..
-
15
-
-
0033580593
-
Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation
-
Hasty AH, Linton MF, Brandt SJ, Babaev VR, Gleaves LA, Fazio S. Retroviral gene therapy in ApoE-deficient mice: ApoE expression in the artery wall reduces early foam cell lesion formation. Circulation 99: 2571-2576, 1999.
-
(1999)
Circulation
, vol.99
, pp. 2571-2576
-
-
Hasty, A.H.1
Linton, M.F.2
Brandt, S.J.3
Babaev, V.R.4
Gleaves, L.A.5
Fazio, S.6
-
16
-
-
0032777213
-
Determination of the lower threshold of apolipoprotein E resulting in remnant lipoprotein clearance
-
Hasty AH, Linton MF, Swift LL, Fazio S. Determination of the lower threshold of apolipoprotein E resulting in remnant lipoprotein clearance. J Lipid Res 40: 1529-1538, 1999.
-
(1999)
J Lipid Res
, vol.40
, pp. 1529-1538
-
-
Hasty, A.H.1
Linton, M.F.2
Swift, L.L.3
Fazio, S.4
-
17
-
-
33845535487
-
Endogenous ApoE expression modulates adipocyte triglyceride content and turnover
-
Huang ZH, Reardon CA, Mazzone T. Endogenous ApoE expression modulates adipocyte triglyceride content and turnover. Diabetes 55: 3394-3402, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 3394-3402
-
-
Huang, Z.H.1
Reardon, C.A.2
Mazzone, T.3
-
18
-
-
0035965336
-
Retrovirus-mediated expression of apolipoprotein A-I in the macrophage protects against atherosclerosis in vivo
-
Ishiguro H, Yoshida H, Major AS, Zhu T, Babaev VR, Linton MF, Fazio S. Retrovirus-mediated expression of apolipoprotein A-I in the macrophage protects against atherosclerosis in vivo. J Biol Chem 276: 36742-36748, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 36742-36748
-
-
Ishiguro, H.1
Yoshida, H.2
Major, A.S.3
Zhu, T.4
Babaev, V.R.5
Linton, M.F.6
Fazio, S.7
-
19
-
-
0035895202
-
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes
-
Laffitte BA, Repa JJ, Joseph SB, Wilpitz DC, Kast HR, Mangelsdorf DJ, Tontonoz P. LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. Proc Nat Acad Sci USA 98: 507-512, 2001.
-
(2001)
Proc Nat Acad Sci USA
, vol.98
, pp. 507-512
-
-
Laffitte, B.A.1
Repa, J.J.2
Joseph, S.B.3
Wilpitz, D.C.4
Kast, H.R.5
Mangelsdorf, D.J.6
Tontonoz, P.7
-
20
-
-
0037180771
-
Inflammation in atherosclerosis
-
Libby P. Inflammation in atherosclerosis. Nature 420: 868-874, 2002.
-
(2002)
Nature
, vol.420
, pp. 868-874
-
-
Libby, P.1
-
21
-
-
0028944150
-
Prevention of atherosclerosis in apoE deficient mice by bone marrow transplantation
-
Linton MF, Atkinson JB, Fazio S. Prevention of atherosclerosis in apoE deficient mice by bone marrow transplantation. Science 267: 1034-1037, 1995.
-
(1995)
Science
, vol.267
, pp. 1034-1037
-
-
Linton, M.F.1
Atkinson, J.B.2
Fazio, S.3
-
22
-
-
0025878638
-
Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation
-
Linton MF, Gish R, Hubl ST, Bütler E, Esquivel C, Bry WI, Boyles JK, Wardell MR, Young SG. Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation. J Clin Invest 88: 270-281, 1991.
-
(1991)
J Clin Invest
, vol.88
, pp. 270-281
-
-
Linton, M.F.1
Gish, R.2
Hubl, S.T.3
Bütler, E.4
Esquivel, C.5
Bry, W.I.6
Boyles, J.K.7
Wardell, M.R.8
Young, S.G.9
-
23
-
-
0034648768
-
Atherosclerosis
-
Lusis AJ. Atherosclerosis. Nature 407: 233-241, 2000.
-
(2000)
Nature
, vol.407
, pp. 233-241
-
-
Lusis, A.J.1
-
24
-
-
0035571680
-
Increased cholesterol efflux in apolipoprotein AI (ApoAI)-producing macrophages as a mechanism for reduced atherosclerosis in apoAI-/- mice
-
Major AS, Dove DE, Ishiguro H, Su YR, Brown AM, Liu L, Carter KJ, Linton MF, Fazio S. Increased cholesterol efflux in apolipoprotein AI (ApoAI)-producing macrophages as a mechanism for reduced atherosclerosis in apoAI-/- mice. Arteroscler Thromb Vasc Biol 21: 1790-1795, 2001.
-
(2001)
Arteroscler Thromb Vasc Biol
, vol.21
, pp. 1790-1795
-
-
Major, A.S.1
Dove, D.E.2
Ishiguro, H.3
Su, Y.R.4
Brown, A.M.5
Liu, L.6
Carter, K.J.7
Linton, M.F.8
Fazio, S.9
-
25
-
-
0037062661
-
Obesity accelerates the progression of coronary atherosclerosis in young men
-
McGill HC Jr, McMahan CA, Herderick EE, Zieske AW, Malcom GT, Tracy RE, Strong JP. Obesity accelerates the progression of coronary atherosclerosis in young men. Circulation 105: 2712-2718, 2002.
-
(2002)
Circulation
, vol.105
, pp. 2712-2718
-
-
McGill Jr, H.C.1
McMahan, C.A.2
Herderick, E.E.3
Zieske, A.W.4
Malcom, G.T.5
Tracy, R.E.6
Strong, J.P.7
-
26
-
-
0028281559
-
Characterization of plasma lipids in genetically obese mice: The mutants obese, diabetes, fat, tubby, and lethal yellow
-
Nishina PM, Lowe S, Wang J, Paigen B. Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. Metabolism 43: 549-553, 1994.
-
(1994)
Metabolism
, vol.43
, pp. 549-553
-
-
Nishina, P.M.1
Lowe, S.2
Wang, J.3
Paigen, B.4
-
27
-
-
0028220011
-
Atherosclerosis in genetically obese mice: The mutants obese, diabetes, fat, tubby, and lethal yellow
-
Nishina PM, Naggert JK, Verstuyft J, Paigen B. Atherosclerosis in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow. Metabolism 43: 554-558, 1994.
-
(1994)
Metabolism
, vol.43
, pp. 554-558
-
-
Nishina, P.M.1
Naggert, J.K.2
Verstuyft, J.3
Paigen, B.4
-
28
-
-
0023634643
-
Quantitative assessment of atherosclerotic lesions in mice
-
Paigen B, Morrow A, Holmes PA, Mitchell D, Williams RA. Quantitative assessment of atherosclerotic lesions in mice. Atherosclerosis 68: 231-240, 1987.
-
(1987)
Atherosclerosis
, vol.68
, pp. 231-240
-
-
Paigen, B.1
Morrow, A.2
Holmes, P.A.3
Mitchell, D.4
Williams, R.A.5
-
29
-
-
0034644663
-
Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissue
-
Shih SJ, Allan C, Grehan S, Tse E, Moran C, Taylor JM. Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissue. J Biol Chem 275: 31567-31572, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 31567-31572
-
-
Shih, S.J.1
Allan, C.2
Grehan, S.3
Tse, E.4
Moran, C.5
Taylor, J.M.6
-
30
-
-
0033548092
-
Increased high density lipoprotein (HDL), defective hepatic catabolism of apoA-I and apoA-II, and decreased apoA-I mRNA in ob/ob mice
-
Silver DL, Jiang XC, Tall AR. Increased high density lipoprotein (HDL), defective hepatic catabolism of apoA-I and apoA-II, and decreased apoA-I mRNA in ob/ob mice. J Biol Chem 274: 4140-4146, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 4140-4146
-
-
Silver, D.L.1
Jiang, X.C.2
Tall, A.R.3
-
31
-
-
0033972321
-
Defective HDL particle uptake in ob/ob hepatocytes causes decreased recycling, degradation, and selective lipid uptake
-
Silver DL, Wang N, Tall AR. Defective HDL particle uptake in ob/ob hepatocytes causes decreased recycling, degradation, and selective lipid uptake. J Clin Invest 105: 151-159, 2000.
-
(2000)
J Clin Invest
, vol.105
, pp. 151-159
-
-
Silver, D.L.1
Wang, N.2
Tall, A.R.3
-
32
-
-
0032830257
-
Rapid regression of atherosclerosis induced by liver-directed gene transfer of apoE in apoE-deficient mice
-
Tsukamoto K, Tangirala R, Chun SH, Pure E, Rader DJ. Rapid regression of atherosclerosis induced by liver-directed gene transfer of apoE in apoE-deficient mice. Aterioscler Thromb Vasc Biol 19: 2162-2170, 1999.
-
(1999)
Aterioscler Thromb Vasc Biol
, vol.19
, pp. 2162-2170
-
-
Tsukamoto, K.1
Tangirala, R.2
Chun, S.H.3
Pure, E.4
Rader, D.J.5
-
33
-
-
19344376244
-
Tissue-specific autoregulation of the LXRalpha gene facilitates induction of apoE in mouse adipose tissue
-
Ulven SM, Dalen KT, Gustafsson JA, Nebb HI. Tissue-specific autoregulation of the LXRalpha gene facilitates induction of apoE in mouse adipose tissue. J Lipid Res 45: 2052-2062, 2004.
-
(2004)
J Lipid Res
, vol.45
, pp. 2052-2062
-
-
Ulven, S.M.1
Dalen, K.T.2
Gustafsson, J.A.3
Nebb, H.I.4
-
34
-
-
0031470817
-
Bone marrow transplantation in apolipoprotein E-deficient mice. Effect of apoE gene dosage on serum lipid concentrations, betaVLDL catabolism, and atherosclerosis
-
VanEck M, Herijgers N, Yates J, Pearce NJ, Hoogerbrugge PM, Berkel TJV. Bone marrow transplantation in apolipoprotein E-deficient mice. Effect of apoE gene dosage on serum lipid concentrations, betaVLDL catabolism, and atherosclerosis. Arterioscl Thromb Vasc Biol 17: 3117-3126, 1997.
-
(1997)
Arterioscl Thromb Vasc Biol
, vol.17
, pp. 3117-3126
-
-
VanEck, M.1
Herijgers, N.2
Yates, J.3
Pearce, N.J.4
Hoogerbrugge, P.M.5
Berkel, T.J.V.6
-
35
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112: 1796-1808, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
36
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H, Barnes G, Yang Q, Tan G, Yang D, Chou C, Sole J, Nichols A, Ross J, Tartaglia LA, Chen H. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112: 1821-1830, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.6
Sole, J.7
Nichols, A.8
Ross, J.9
Tartaglia, L.A.10
Chen, H.11
-
37
-
-
0035808002
-
Isoform-Specific Effects of Apolipoprotein E on Atherogenesis: Gene transduction studies in apoE-null mice
-
Yoshida H, Hasty A, Major AS, Ishiguro H, Su Y, Gleaves LA, Babaev VR, Linton MF, Fazio S. Isoform-Specific Effects of Apolipoprotein E on Atherogenesis: Gene transduction studies in apoE-null mice. Circulation 104: 2820-2825, 2001.
-
(2001)
Circulation
, vol.104
, pp. 2820-2825
-
-
Yoshida, H.1
Hasty, A.2
Major, A.S.3
Ishiguro, H.4
Su, Y.5
Gleaves, L.A.6
Babaev, V.R.7
Linton, M.F.8
Fazio, S.9
-
38
-
-
9144242586
-
Divergent effects of peroxisome proliferator-activated receptor gamma agonists and tumor necrosis factor alpha on adipocyte ApoE expression
-
Yue L, Rasouli N, Ranganathan G, Kern PA, Mazzone T. Divergent effects of peroxisome proliferator-activated receptor gamma agonists and tumor necrosis factor alpha on adipocyte ApoE expression. J Biol Chem 279: 47626-47632, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 47626-47632
-
-
Yue, L.1
Rasouli, N.2
Ranganathan, G.3
Kern, P.A.4
Mazzone, T.5
-
39
-
-
0025821171
-
Apolipoprotein E gene expression in mouse 3T3-L1 adipocytes and human adipose tissue and its regulation by differentiation and lipid content
-
Zechner R, Moser R, Newman TC, Fried SK, Breslow JL. Apolipoprotein E gene expression in mouse 3T3-L1 adipocytes and human adipose tissue and its regulation by differentiation and lipid content. J Biol Chem 266: 10583-10588, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 10583-10588
-
-
Zechner, R.1
Moser, R.2
Newman, T.C.3
Fried, S.K.4
Breslow, J.L.5
|