Primordial Germ Cells: What Does It Take to Be Alive?

Molecular Reproduction and Development

Volumn 68, Issue 1, 2004, Pages 1-4

  Tres, Laura L ^a   Rosselot, Carolina ^a   Kierszenbaum, Abraham L ^a  

^a CITY UNIVERSITY OF NEW YORK MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Fragilis; Nanos; Stella; Stem cell factor

Indexed keywords

BCL21 PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 8B; FIBROBLAST GROWTH FACTOR; MEMBRANE PROTEIN; NANO3 PROTEIN; PROTEIN; PROTEIN BAX; PROTEIN BCL X; SMAD PROTEIN; STEM CELL FACTOR; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

APOPTOSIS; AUTOCRINE EFFECT; CELL ADHESION; CELL CONTACT; CELL LINEAGE; CELL MIGRATION; CELL MOTION; CELL POPULATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; ECTODERM; EMBRYO (ANATOMY); FRAGILIS GENE; GENE; GENE EXPRESSION; GERM CELL; IN VITRO STUDY; NANO3 GENE; OVARY; PARACRINE SIGNALING; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; REVIEW; SOMATIC CELL; STELLA GENE; TESTIS;

ANIMALS; CELL MOVEMENT; CELL SURVIVAL; GENE EXPRESSION REGULATION; GERM CELLS; GROWTH SUBSTANCES; SIGNAL TRANSDUCTION;

STELLA;

EID: 1842532922     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.20056     Document Type: Review

References (15)

1. Donovan PJ. 1994. Growth factor regulation of mouse primordial germ cell development. Curr Top Dev Biol 29:189-225.
2. Godin I, Wylie CC. 1991. TGFβ1 inhibits proliferation and has a chemotropic effect on mouse germ cells in culture. Development 113: 1451-1457.
3. Jaruzelska J, Kotecki M, Kusz K, Spik A, Firpo M, Reijo Pera RA. 2003. Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells. Dev Genes Evol 213:120-126.
4. Kawase E, Hashimoto K, Pedersen RA. 2004. Autocrine and paracrine mechanisms regulating primordial germ cell proliferation. Mol Reprod Dev 68:5-16.
5. Kierszenbaum AL, Tres LL. 2001. Primordial germ cell-somatic cell partnership: a balancing cell signaling act. Mol Reprod Dev 60:277-280.
6. McLaren A. 2003. Primordial germ cells in the mouse. Dev Biol 262:1-15.
7. Molyneaux KA, Stallock J, Schaible K, Wylie C. 2001. Time-lapse analysis of primordial germ cells in the mouse. J Exp Zool 134:207-237.
8. Rosselot C, Kierszenbaum AL, Rivkin E, Tres LL. 2003. Chronological gene expression of ADAMS during testicular development: Prespermatogonia (gonocytes) express fertilin β (ADAM2). Dev Dynam 227: 458-467.
9. Rucker EB, Dierisseau P, Wagner K-U, Garrett L, Wynshaw-Boris A, Flaws JA, Hennighausen L. 2000. Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis. Mol Endocrinol 14:1038-1052.
10. Saitou M, Barton SC, Surani MA. 2002. A molecular programme for the specification of germ cell fate in mice. Nature 418:293-300.
11. Schneider DT, Schuster AE, Fritsch MK, Hu J, Olson T, Lauer S, Gobel U, Perlman EJ. 2001. Multipoint imprinting analysis indicates a common precursor cell for gonadal and nongonadal pediatric germ cell tumors. Cancer Res 61:7268-7276.
12. Subramaniam K, Seydoux G. 1999. nos-1 and nos-2, two genes related to Drosophila nanos, regulate primordial germ cell development and survival in Caenorhabditis elegans. Development 126:4861-4871.
13. Tsuda M, Sasaoka Y, Kiso M, Abe K, Haraguchi S, Kobayashi S, Saga Y. 2003. Conserved role of nanos proteins in germ cell development. Science 301:1239-1241.
14. Williams DE, De Vries P, Namen AE, Widmer MB, Lyman SD. 1992. The steel factor. Dev Biol 151:368-376.
15. Wylie C. 1999. Germ cells. Cell 96:165-174.