메뉴 건너뛰기




Volumn 5, Issue 1, 2008, Pages 0090-0103

Enhancing exposure of HIV-1 neutralization epitopes through mutations in gp41

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; PROTEIN GP41; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; VIRUS PROTEIN; GLYCOPROTEIN GP 41; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN;

EID: 38849205377     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.0050009     Document Type: Article
Times cited : (78)

References (60)
  • 1
    • 2942534479 scopus 로고    scopus 로고
    • Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies
    • Ferrantelli F, Rasmussen RA, Buckley KA, Li PL, Wang T, et al. (2004) Complete protection of neonatal rhesus macaques against oral exposure to pathogenic simian-human immunodeficiency virus by human anti-HIV monoclonal antibodies. J Infect Dis 189: 2167-2173.
    • (2004) J Infect Dis , vol.189 , pp. 2167-2173
    • Ferrantelli, F.1    Rasmussen, R.A.2    Buckley, K.A.3    Li, P.L.4    Wang, T.5
  • 2
    • 0032947286 scopus 로고    scopus 로고
    • Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies
    • Mascola JR, Lewis MG, Stiegler G, Harris D, VanCott TC, et al. (1999) Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies. J Virol 73: 4009-4018.
    • (1999) J Virol , vol.73 , pp. 4009-4018
    • Mascola, J.R.1    Lewis, M.G.2    Stiegler, G.3    Harris, D.4    VanCott, T.C.5
  • 3
    • 0033951746 scopus 로고    scopus 로고
    • Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
    • Mascola JR, Stiegler G, VanCott TC, Katinger H, Carpenter CB, et al. (2000) Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat Med 6: 207-210.
    • (2000) Nat Med , vol.6 , pp. 207-210
    • Mascola, J.R.1    Stiegler, G.2    VanCott, T.C.3    Katinger, H.4    Carpenter, C.B.5
  • 4
    • 0034864776 scopus 로고    scopus 로고
    • Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/ human immunodeficiency virus at serum levels giving complete neutralization in vitro
    • Parren PW, Marx PA, Hessell AJ, Luckay A, Harouse J, et al. (2001) Antibody protects macaques against vaginal challenge with a pathogenic R5 simian/ human immunodeficiency virus at serum levels giving complete neutralization in vitro. J Virol 75: 8340-8347.
    • (2001) J Virol , vol.75 , pp. 8340-8347
    • Parren, P.W.1    Marx, P.A.2    Hessell, A.J.3    Luckay, A.4    Harouse, J.5
  • 5
    • 0032907674 scopus 로고    scopus 로고
    • Neutralizing antibody directed against the HIV-1 envelope glycoprotein can completely block HIV-1/SIV chimeric virus infections of macaque monkeys
    • Shibata R, Igarashi T, Haigwood N, Buckler-White A, Ogert R, et al. (1999) Neutralizing antibody directed against the HIV-1 envelope glycoprotein can completely block HIV-1/SIV chimeric virus infections of macaque monkeys. Nat Med 5: 204-210.
    • (1999) Nat Med , vol.5 , pp. 204-210
    • Shibata, R.1    Igarashi, T.2    Haigwood, N.3    Buckler-White, A.4    Ogert, R.5
  • 6
    • 2542493991 scopus 로고    scopus 로고
    • Role of neutralizing antibodies in HIV infection
    • Haigwood NL, Stamatatos L (2003) Role of neutralizing antibodies in HIV infection. AIDS 17: S67-71.
    • (2003) AIDS , vol.17
    • Haigwood, N.L.1    Stamatatos, L.2
  • 9
    • 0037069682 scopus 로고    scopus 로고
    • HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
    • Kwong PD, Doyle ML, Casper DJ, Cicala C, Leavitt SA, et al. (2002) HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites. Nature 420: 678-682.
    • (2002) Nature , vol.420 , pp. 678-682
    • Kwong, P.D.1    Doyle, M.L.2    Casper, D.J.3    Cicala, C.4    Leavitt, S.A.5
  • 10
    • 17944380435 scopus 로고    scopus 로고
    • Crystal structure of a neutralizing human IGG against HIV-1: A template for vaccine design
    • Saphire EO, Parren PW, Pantophlet R, Zwick MB, Morris GM, et al. (2001) Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design. Science 293: 1155-1159.
    • (2001) Science , vol.293 , pp. 1155-1159
    • Saphire, E.O.1    Parren, P.W.2    Pantophlet, R.3    Zwick, M.B.4    Morris, G.M.5
  • 11
    • 33847101745 scopus 로고    scopus 로고
    • Structural definition of a conserved neutralization epitope on HIV-1 gp120
    • Zhou T, Xu L, Dey B, Hessell AJ, Van Ryk D, et al. (2007) Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature 445: 732-737.
    • (2007) Nature , vol.445 , pp. 732-737
    • Zhou, T.1    Xu, L.2    Dey, B.3    Hessell, A.J.4    Van Ryk, D.5
  • 12
    • 33947635198 scopus 로고    scopus 로고
    • The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes
    • Alam SM, McAdams M, Boren D, Rak M, Scearce RM, et al. (2007) The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes. J Immunol 178: 4424-4435.
    • (2007) J Immunol , vol.178 , pp. 4424-4435
    • Alam, S.M.1    McAdams, M.2    Boren, D.3    Rak, M.4    Scearce, R.M.5
  • 13
    • 21344434534 scopus 로고    scopus 로고
    • Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies
    • Haynes BF, Fleming J, St Clair EW, Katinger H, Stiegler G, et al. (2005) Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies. Science 308: 1906-1908.
    • (2005) Science , vol.308 , pp. 1906-1908
    • Haynes, B.F.1    Fleming, J.2    St Clair, E.W.3    Katinger, H.4    Stiegler, G.5
  • 14
    • 23244434512 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies
    • Li M, Gao F, Mascola JR, Stamatatos L, Polonis VR, et al. (2005) Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies. J Virol 79: 10108-10125.
    • (2005) J Virol , vol.79 , pp. 10108-10125
    • Li, M.1    Gao, F.2    Mascola, J.R.3    Stamatatos, L.4    Polonis, V.R.5
  • 15
    • 33751224478 scopus 로고    scopus 로고
    • Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa
    • Li M, Salazar-Gonzalez JF, Derdeyn CA, Morris L, Williamson C, et al. (2006) Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa. J Virol 80: 11776-11790.
    • (2006) J Virol , vol.80 , pp. 11776-11790
    • Li, M.1    Salazar-Gonzalez, J.F.2    Derdeyn, C.A.3    Morris, L.4    Williamson, C.5
  • 16
    • 20744442398 scopus 로고    scopus 로고
    • Virus isolates during acute and chronic human immunodeficiency virus type 1 infection show distinct patterns of sensitivity to entry inhibitors
    • Rusert P, Kuster H, Joos B, Misselwitz B, Gujer C, et al. (2005) Virus isolates during acute and chronic human immunodeficiency virus type 1 infection show distinct patterns of sensitivity to entry inhibitors. J Virol 79: 8454-8469.
    • (2005) J Virol , vol.79 , pp. 8454-8469
    • Rusert, P.1    Kuster, H.2    Joos, B.3    Misselwitz, B.4    Gujer, C.5
  • 17
    • 34147180438 scopus 로고    scopus 로고
    • HIV-1 Subtype A Envelope Variants from Early in Infection Have Variable Sensitivity to Neutralization and to inhibitors of Viral Entry
    • Blish C, Nedellec R, Mandaliya K, Mosier D, Overbaugh J (2007) HIV-1 Subtype A Envelope Variants from Early in Infection Have Variable Sensitivity to Neutralization and to inhibitors of Viral Entry. AIDS 6: 693-702.
    • (2007) AIDS , vol.6 , pp. 693-702
    • Blish, C.1    Nedellec, R.2    Mandaliya, K.3    Mosier, D.4    Overbaugh, J.5
  • 18
    • 10044280760 scopus 로고    scopus 로고
    • Neutralization profiles of newly transmitted human immunodeficiency virus type 1 by monoclonal antibodies 2G12, 2F5, and 4E10
    • Mehandru S, Wrin T, Galovich J, Stiegler G, Vcelar B, et al. (2004) Neutralization profiles of newly transmitted human immunodeficiency virus type 1 by monoclonal antibodies 2G12, 2F5, and 4E10. J Virol 78: 14039-14042.
    • (2004) J Virol , vol.78 , pp. 14039-14042
    • Mehandru, S.1    Wrin, T.2    Galovich, J.3    Stiegler, G.4    Vcelar, B.5
  • 19
    • 12144289425 scopus 로고    scopus 로고
    • Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission
    • Derdeyn CA, Decker JM, Bibollet-Ruche F, Mokili JL, Muldoon M, et al. (2004) Envelope-constrained neutralization-sensitive HIV-1 after heterosexual transmission. Science 303: 2019-2022.
    • (2004) Science , vol.303 , pp. 2019-2022
    • Derdeyn, C.A.1    Decker, J.M.2    Bibollet-Ruche, F.3    Mokili, J.L.4    Muldoon, M.5
  • 20
    • 0036260635 scopus 로고    scopus 로고
    • HIV Type 1 Variants transmitted to women in Kenya require the CCR5 coreceptor for entry, regardless of the genetic complexity of the infecting virus
    • Long EM, Rainwater SMJ, Lavreys L, Mandaliya K, Overbaugh J (2002) HIV Type 1 Variants transmitted to women in Kenya require the CCR5 coreceptor for entry, regardless of the genetic complexity of the infecting virus. AIDS Res Hum Retroviruses 18: 567-576.
    • (2002) AIDS Res Hum Retroviruses , vol.18 , pp. 567-576
    • Long, E.M.1    Rainwater, S.M.J.2    Lavreys, L.3    Mandaliya, K.4    Overbaugh, J.5
  • 21
    • 8444219998 scopus 로고    scopus 로고
    • Association of levels of HIV-1-infected breast milk cells and risk of mother-to-child transmission
    • Rousseau CM, Nduati RW, Richardson BA, John-Stewart GC, Mbori-Ngacha DA, et al. (2004) Association of levels of HIV-1-infected breast milk cells and risk of mother-to-child transmission. J Infect Dis 190: 1880-1888.
    • (2004) J Infect Dis , vol.190 , pp. 1880-1888
    • Rousseau, C.M.1    Nduati, R.W.2    Richardson, B.A.3    John-Stewart, G.C.4    Mbori-Ngacha, D.A.5
  • 22
    • 33845579438 scopus 로고    scopus 로고
    • Quantification of genital human immunodeficiency virus type 1 (HIV-1) DNA in specimens from women with low plasma HIV-1 RNA levels typical of HIV-1 nontransmitters
    • Benki S, McClelland RS, Emery S, Baeten JM, Richardson BA, et al. (2006) Quantification of genital human immunodeficiency virus type 1 (HIV-1) DNA in specimens from women with low plasma HIV-1 RNA levels typical of HIV-1 nontransmitters. J Clin Microbiol 44: 4357-4362.
    • (2006) J Clin Microbiol , vol.44 , pp. 4357-4362
    • Benki, S.1    McClelland, R.S.2    Emery, S.3    Baeten, J.M.4    Richardson, B.A.5
  • 23
    • 0027998192 scopus 로고
    • Preparation for AIDS vaccine evaluation in Mombasa, Kenya: Establishment of seronegative cohorts of commercial sex workers and trucking company employees
    • Martin HL, Jackson DJ, Mandaliya K, Bwayo J, Rakwar JP, et al. (1994) Preparation for AIDS vaccine evaluation in Mombasa, Kenya: establishment of seronegative cohorts of commercial sex workers and trucking company employees. AIDS Res Hum Retroviruses 10: S235-S237.
    • (1994) AIDS Res Hum Retroviruses , vol.10
    • Martin, H.L.1    Jackson, D.J.2    Mandaliya, K.3    Bwayo, J.4    Rakwar, J.P.5
  • 24
    • 17344365344 scopus 로고    scopus 로고
    • Hormonal contraception, sexually transmitted diseases, and the risk of heterosexual transmission of HIV-1
    • Martin HL, Nyange PM, Richardson BA, Lavreys L, Mandaliya K, et al. (1998) Hormonal contraception, sexually transmitted diseases, and the risk of heterosexual transmission of HIV-1. J Infect Dis 178: 1053-1059.
    • (1998) J Infect Dis , vol.178 , pp. 1053-1059
    • Martin, H.L.1    Nyange, P.M.2    Richardson, B.A.3    Lavreys, L.4    Mandaliya, K.5
  • 25
    • 30344438528 scopus 로고    scopus 로고
    • No evidence for rapid subtype c spread within an epidemic in which multiple subtypes and intersubtype recombinants circulate
    • Rainwater S, Devange S, Sagar M, Ndinya-Achola J, Mandaliya K, et al. (2005) No evidence for rapid subtype c spread within an epidemic in which multiple subtypes and intersubtype recombinants circulate. AIDS Res Hum Retroviruses 21: 1060-1065.
    • (2005) AIDS Res Hum Retroviruses , vol.21 , pp. 1060-1065
    • Rainwater, S.1    Devange, S.2    Sagar, M.3    Ndinya-Achola, J.4    Mandaliya, K.5
  • 26
    • 0342506507 scopus 로고    scopus 로고
    • Indicator cell lines for detection of primary strains of human and simian immunodeficiency viruses
    • Vodicka MA, Goh WC, Wu LI, Rogel ME, Bartz SR, et al. (1997) Indicator cell lines for detection of primary strains of human and simian immunodeficiency viruses. Virology 233: 193-198.
    • (1997) Virology , vol.233 , pp. 193-198
    • Vodicka, M.A.1    Goh, W.C.2    Wu, L.I.3    Rogel, M.E.4    Bartz, S.R.5
  • 27
    • 30344485709 scopus 로고    scopus 로고
    • Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infant
    • Wu X, Parast AB, Richardson BA, Nduati R, John-Stewart G, et al. (2006) Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infant. J Virol 80: 835-844.
    • (2006) J Virol , vol.80 , pp. 835-844
    • Wu, X.1    Parast, A.B.2    Richardson, B.A.3    Nduati, R.4    John-Stewart, G.5
  • 28
    • 23844468382 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 subtype B ancestral envelope protein is functional and elicits neutralizing antibodies in rabbits similar to those elicited by a circulating subtype B envelope
    • Doria-Rose NA, Learn GH, Rodrigo AG, Nickle DC, Li F, et al. (2005) Human immunodeficiency virus type 1 subtype B ancestral envelope protein is functional and elicits neutralizing antibodies in rabbits similar to those elicited by a circulating subtype B envelope. J Virol 79: 11214-11224.
    • (2005) J Virol , vol.79 , pp. 11214-11224
    • Doria-Rose, N.A.1    Learn, G.H.2    Rodrigo, A.G.3    Nickle, D.C.4    Li, F.5
  • 29
    • 13844255333 scopus 로고    scopus 로고
    • Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41
    • Cardoso RM, Zwick MB, Stanfield RL, Kunert R, Binley JM, et al. (2005) Broadly neutralizing anti-HIV antibody 4E10 recognizes a helical conformation of a highly conserved fusion-associated motif in gp41. Immunity 22: 163-173.
    • (2005) Immunity , vol.22 , pp. 163-173
    • Cardoso, R.M.1    Zwick, M.B.2    Stanfield, R.L.3    Kunert, R.4    Binley, J.M.5
  • 30
    • 11144227042 scopus 로고    scopus 로고
    • Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1
    • Zwick MB, Jensen R, Church S, Wang M, Stiegler G, et al. (2005) Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycoprotein gp41 to neutralize HIV-1. J Virol 79: 1252-1261.
    • (2005) J Virol , vol.79 , pp. 1252-1261
    • Zwick, M.B.1    Jensen, R.2    Church, S.3    Wang, M.4    Stiegler, G.5
  • 31
    • 0027985431 scopus 로고
    • Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody
    • Burton DR, Pyati J, Koduri R, Sharp SJ, Thornton GB, et al. (1994) Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody. Science 266: 1024-1027.
    • (1994) Science , vol.266 , pp. 1024-1027
    • Burton, D.R.1    Pyati, J.2    Koduri, R.3    Sharp, S.J.4    Thornton, G.B.5
  • 32
    • 0026655937 scopus 로고
    • Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro
    • Barbas CF 3rd, Bjorling E, Chiodi F, Dunlop N, Cababa D, et al. (1992) Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro. Proc Natl Acad Sci U S A 89: 9339-9343.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 9339-9343
    • Barbas 3rd, C.F.1    Bjorling, E.2    Chiodi, F.3    Dunlop, N.4    Cababa, D.5
  • 33
    • 0037059049 scopus 로고    scopus 로고
    • Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics
    • Reeves JD, Gallo SA, Ahmad N, Miamidian JL, Harvey PE, et al. (2002) Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics. Proc Natl Acad Sci U S A 99: 16249-16254.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 16249-16254
    • Reeves, J.D.1    Gallo, S.A.2    Ahmad, N.3    Miamidian, J.L.4    Harvey, P.E.5
  • 34
    • 16244380203 scopus 로고    scopus 로고
    • Enfuvirtide resistance mutations: Impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity, and virus neutralization
    • Reeves JD, Lee FH, Miamidian JL, Jabara CB, Juntilla MM, et al. (2005) Enfuvirtide resistance mutations: impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity, and virus neutralization. J Virol 79: 4991-4999.
    • (2005) J Virol , vol.79 , pp. 4991-4999
    • Reeves, J.D.1    Lee, F.H.2    Miamidian, J.L.3    Jabara, C.B.4    Juntilla, M.M.5
  • 35
    • 2342514225 scopus 로고    scopus 로고
    • Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity
    • Reeves JD, Miamidian JL, Biscone MJ, Lee FH, Ahmad N, et al. (2004) Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity. J Virol 78: 5476-5485.
    • (2004) J Virol , vol.78 , pp. 5476-5485
    • Reeves, J.D.1    Miamidian, J.L.2    Biscone, M.J.3    Lee, F.H.4    Ahmad, N.5
  • 36
    • 26444523534 scopus 로고    scopus 로고
    • In vitro generation of HIV type 1 subtype C isolates resistant to enfuvirtide
    • Cilliers T, Moore P, Coetzer M, Morris L (2005) In vitro generation of HIV type 1 subtype C isolates resistant to enfuvirtide. AIDS Res Hum Retroviruses 21: 776-783.
    • (2005) AIDS Res Hum Retroviruses , vol.21 , pp. 776-783
    • Cilliers, T.1    Moore, P.2    Coetzer, M.3    Morris, L.4
  • 37
    • 20844448731 scopus 로고    scopus 로고
    • Antigenic conservation and immunogenicity of the HIV coreceptor binding site
    • Decker JM, Bibollet-Ruche F, Wei X, Wang S, Levy DN, et al. (2005) Antigenic conservation and immunogenicity of the HIV coreceptor binding site. J Exp Med 201: 1407-1419.
    • (2005) J Exp Med , vol.201 , pp. 1407-1419
    • Decker, J.M.1    Bibollet-Ruche, F.2    Wei, X.3    Wang, S.4    Levy, D.N.5
  • 38
    • 0032990223 scopus 로고    scopus 로고
    • Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein
    • Hoffman TL, LaBranche CC, Zhang W, Canziani G, Robinson J, et al. (1999) Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein. Proc Natl Acad Sci U S A 96: 6359-6364.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6359-6364
    • Hoffman, T.L.1    LaBranche, C.C.2    Zhang, W.3    Canziani, G.4    Robinson, J.5
  • 39
    • 0026085170 scopus 로고
    • Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibody
    • Thali M, Olshevsky U, Furman C, Gabuzda D, Posner M, et al. (1991) Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibody. J Virol 65: 6188-6193.
    • (1991) J Virol , vol.65 , pp. 6188-6193
    • Thali, M.1    Olshevsky, U.2    Furman, C.3    Gabuzda, D.4    Posner, M.5
  • 40
    • 0035100868 scopus 로고    scopus 로고
    • Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1/V2 variable loops
    • Kolchinsky P, Kiprilov E, Bartley P, Rubinstein R, Sodroski J (2001) Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1/V2 variable loops. J Virol 75: 3435-3443.
    • (2001) J Virol , vol.75 , pp. 3435-3443
    • Kolchinsky, P.1    Kiprilov, E.2    Bartley, P.3    Rubinstein, R.4    Sodroski, J.5
  • 41
    • 0025815375 scopus 로고
    • Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: Identification of replication-competent and -defective viral genomes
    • Li Y, Kappes JC, Conway JA, Price RW, Shaw GM, et al. (1991) Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes. J Virol 65: 3973-3985.
    • (1991) J Virol , vol.65 , pp. 3973-3985
    • Li, Y.1    Kappes, J.C.2    Conway, J.A.3    Price, R.W.4    Shaw, G.M.5
  • 42
    • 0025281325 scopus 로고
    • The site of an immune-selected point mutation in the transmembrane protein of human immunodeficiency virus type 1 does not constitute the neutralization epitope
    • Wilson C, Reitz MS Jr., Aldrich K, Klasse PJ, Blomberg J, et al. (1990) The site of an immune-selected point mutation in the transmembrane protein of human immunodeficiency virus type 1 does not constitute the neutralization epitope. J Virol 64: 3240-3248.
    • (1990) J Virol , vol.64 , pp. 3240-3248
    • Wilson, C.1    Reitz Jr., M.S.2    Aldrich, K.3    Klasse, P.J.4    Blomberg, J.5
  • 43
    • 0027170295 scopus 로고
    • An immune-selected point mutation in the transmembrane protein of human immunodeficiency virus type 1 (HXB2-Env:Ala 582(→Thr)) decreases viral neutralization by monoclonal antibodies to the CD4-binding site
    • Klasse PJ, McKeating JA, Schutten M, Reitz MS Jr., Robert-Guroff M (1993) An immune-selected point mutation in the transmembrane protein of human immunodeficiency virus type 1 (HXB2-Env:Ala 582(→Thr)) decreases viral neutralization by monoclonal antibodies to the CD4-binding site. Virology 196: 332-337.
    • (1993) Virology , vol.196 , pp. 332-337
    • Klasse, P.J.1    McKeating, J.A.2    Schutten, M.3    Reitz Jr., M.S.4    Robert-Guroff, M.5
  • 44
    • 0027486487 scopus 로고
    • Mutations in human immunodeficiency virus type 1 gp41 affect sensitivity to neutralization by gp120 antibodies
    • Back NK, Smit L, Schutten M, Nara PL, Tersmette M, et al. (1993) Mutations in human immunodeficiency virus type 1 gp41 affect sensitivity to neutralization by gp120 antibodies. J Virol 67: 6897-6902.
    • (1993) J Virol , vol.67 , pp. 6897-6902
    • Back, N.K.1    Smit, L.2    Schutten, M.3    Nara, P.L.4    Tersmette, M.5
  • 45
    • 0031846519 scopus 로고    scopus 로고
    • Mutations in both gp120 and gp41 are responsible for the broad neutralization resistance of variant human immunodeficiency virus type 1 MN to antibodies directed at V3 and non-V3 epitopes
    • Park EJ, Vujcic LK, Anand R, Theodore TS, Quinnan GV Jr. (1998) Mutations in both gp120 and gp41 are responsible for the broad neutralization resistance of variant human immunodeficiency virus type 1 MN to antibodies directed at V3 and non-V3 epitopes. J Virol 72: 7099-7107.
    • (1998) J Virol , vol.72 , pp. 7099-7107
    • Park, E.J.1    Vujcic, L.K.2    Anand, R.3    Theodore, T.S.4    Quinnan Jr., G.V.5
  • 46
    • 0034000472 scopus 로고    scopus 로고
    • A global neutralization resistance phenotype of human immunodeficiency virus type 1 is determined by distinct mechanisms mediating enhanced infectivity and conformational change of the envelope complex
    • Park EJ, Gorny MK, Zolla-Pazner S, Quinnan GV Jr. (2000) A global neutralization resistance phenotype of human immunodeficiency virus type 1 is determined by distinct mechanisms mediating enhanced infectivity and conformational change of the envelope complex. J Virol 74: 4183-4191.
    • (2000) J Virol , vol.74 , pp. 4183-4191
    • Park, E.J.1    Gorny, M.K.2    Zolla-Pazner, S.3    Quinnan Jr., G.V.4
  • 47
    • 0024040544 scopus 로고
    • Generation of a neutralization-resistant variant of HIV-1 is due to selection for a point mutation in the envelope gene
    • Reitz MS Jr., Wilson C, Naugle C, Gallo RC, Robert-Guroff M (1988) Generation of a neutralization-resistant variant of HIV-1 is due to selection for a point mutation in the envelope gene. Cell 54: 57-63.
    • (1988) Cell , vol.54 , pp. 57-63
    • Reitz Jr., M.S.1    Wilson, C.2    Naugle, C.3    Gallo, R.C.4    Robert-Guroff, M.5
  • 48
    • 0027976321 scopus 로고
    • Resistance to neutralization by broadly reactive antibodies to the human immunodeficiency virus type 1 gp120 glycoprotein conferred by a gp41 amino acid change
    • Thali M, Charles M, Furman C, Cavacini L, Posner M, et al. (1994) Resistance to neutralization by broadly reactive antibodies to the human immunodeficiency virus type 1 gp120 glycoprotein conferred by a gp41 amino acid change. J Virol 68: 674-680.
    • (1994) J Virol , vol.68 , pp. 674-680
    • Thali, M.1    Charles, M.2    Furman, C.3    Cavacini, L.4    Posner, M.5
  • 49
    • 0029861654 scopus 로고    scopus 로고
    • Resistance of human immunodeficiency virus type 1 to neutralization by natural antisera occurs through single amino acid substitutions that cause changes in antibody binding at multiple sites
    • Watkins BA, Buge S, Aldrich K, Davis AE, Robinson J, et al. (1996) Resistance of human immunodeficiency virus type 1 to neutralization by natural antisera occurs through single amino acid substitutions that cause changes in antibody binding at multiple sites. J Virol 70: 8431-8437.
    • (1996) J Virol , vol.70 , pp. 8431-8437
    • Watkins, B.A.1    Buge, S.2    Aldrich, K.3    Davis, A.E.4    Robinson, J.5
  • 50
    • 8644251891 scopus 로고    scopus 로고
    • Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies
    • Binley JM, Wrin T, Korber B, Zwick MB, Wang M, et al. (2004) Comprehensive cross-clade neutralization analysis of a panel of anti-human immunodeficiency virus type 1 monoclonal antibodies. J Virol 78: 13232-13252.
    • (2004) J Virol , vol.78 , pp. 13232-13252
    • Binley, J.M.1    Wrin, T.2    Korber, B.3    Zwick, M.B.4    Wang, M.5
  • 51
    • 25144432396 scopus 로고    scopus 로고
    • Virion envelope content, infectivity, and neutralization sensitivity of simian immunodeficiency virus
    • Yuste E, Johnson W, Pavlakis GN, Desrosiers RC (2005) Virion envelope content, infectivity, and neutralization sensitivity of simian immunodeficiency virus. J Virol 79: 12455-12463.
    • (2005) J Virol , vol.79 , pp. 12455-12463
    • Yuste, E.1    Johnson, W.2    Pavlakis, G.N.3    Desrosiers, R.C.4
  • 52
    • 0038671938 scopus 로고    scopus 로고
    • The hydrophobic pocket contributes to the structural stability of the N-terminal coiled coil of HIV gp41 but is not required for six-helix bundle formation
    • Dwyer JJ, Hasan A, Wilson KL, White JM, Matthews TJ, et al. (2003) The hydrophobic pocket contributes to the structural stability of the N-terminal coiled coil of HIV gp41 but is not required for six-helix bundle formation. Biochemistry 42: 4945-4953.
    • (2003) Biochemistry , vol.42 , pp. 4945-4953
    • Dwyer, J.J.1    Hasan, A.2    Wilson, K.L.3    White, J.M.4    Matthews, T.J.5
  • 53
    • 0345060499 scopus 로고    scopus 로고
    • Role of the fusion peptide and membrane-proximal domain in HIV-1 envelope glycoprotein-mediated membrane fusion
    • Dimitrov AS, Rawat SS, Jiang S, Blumenthal R (2003) Role of the fusion peptide and membrane-proximal domain in HIV-1 envelope glycoprotein-mediated membrane fusion. Biochemistry 42: 14150-14158.
    • (2003) Biochemistry , vol.42 , pp. 14150-14158
    • Dimitrov, A.S.1    Rawat, S.S.2    Jiang, S.3    Blumenthal, R.4
  • 54
    • 7044231888 scopus 로고    scopus 로고
    • Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction
    • Mo H, Konstantinidis AK, Stewart KD, Dekhtyar T, Ng T, et al. (2004) Conserved residues in the coiled-coil pocket of human immunodeficiency virus type 1 gp41 are essential for viral replication and interhelical interaction. Virology 329: 319-327.
    • (2004) Virology , vol.329 , pp. 319-327
    • Mo, H.1    Konstantinidis, A.K.2    Stewart, K.D.3    Dekhtyar, T.4    Ng, T.5
  • 55
    • 0031058386 scopus 로고    scopus 로고
    • Poumbourios P, Wilson KA, Center RJ, El-Ahmar W, Kemp BE (1997) Human immunodeficiency virus type 1 envelope glycoprotein oligomerization requires the gp41 amphipathic alpha-helical/leucine zipper-like sequence. J Virol 71: 2041-2049.
    • Poumbourios P, Wilson KA, Center RJ, El-Ahmar W, Kemp BE (1997) Human immunodeficiency virus type 1 envelope glycoprotein oligomerization requires the gp41 amphipathic alpha-helical/leucine zipper-like sequence. J Virol 71: 2041-2049.
  • 56
    • 16244367157 scopus 로고    scopus 로고
    • Human immunodeficiency virus (HIV) gp41 escape mutants: Cross-resistance to peptide inhibitors of HIV fusion and altered receptor activation of gp120
    • Desmezieres E, Gupta N, Vassell R, He Y, Peden K, et al. (2005) Human immunodeficiency virus (HIV) gp41 escape mutants: cross-resistance to peptide inhibitors of HIV fusion and altered receptor activation of gp120. J Virol 79: 4774-4781.
    • (2005) J Virol , vol.79 , pp. 4774-4781
    • Desmezieres, E.1    Gupta, N.2    Vassell, R.3    He, Y.4    Peden, K.5
  • 57
    • 33646146379 scopus 로고    scopus 로고
    • GP120: Target for neutralizing HIV-1 antibodies
    • Pantophlet R, Burton DR (2006) GP120: target for neutralizing HIV-1 antibodies. Annu Rev Immunol 24: 739-769.
    • (2006) Annu Rev Immunol , vol.24 , pp. 739-769
    • Pantophlet, R.1    Burton, D.R.2
  • 59
    • 0038638590 scopus 로고    scopus 로고
    • HIV vaccines 1983-2003
    • McMichael AJ, Hanke T (2003) HIV vaccines 1983-2003. Nat Med 9: 874-880.
    • (2003) Nat Med , vol.9 , pp. 874-880
    • McMichael, A.J.1    Hanke, T.2
  • 60
    • 0026726809 scopus 로고
    • Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: Evidence for limited defectiveness and complementation
    • Li Y, Hui H, Burgess CJ, Price RW, Sharp PM, et al. (1992) Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: evidence for limited defectiveness and complementation. J Virol 66: 6587-6600.
    • (1992) J Virol , vol.66 , pp. 6587-6600
    • Li, Y.1    Hui, H.2    Burgess, C.J.3    Price, R.W.4    Sharp, P.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.