Effect of propofol on pathologic time-course and apoptosis after cerebral ischemia-reperfusion injury

Acta Anaesthesiologica Scandinavica

Volumn 52, Issue 3, 2008, Pages 413-419

  Chen, L ^a   Xue, Z ^a   Jiang, Hao ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Apoptosis; Cerebral ischemia; Propofol; Therapeutic window

Indexed keywords

PROPOFOL; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; BRAIN PERFUSION; CONTROLLED STUDY; DISEASE DURATION; DRUG DETERMINATION; IMMUNOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; EDEMA; MALE; NEURONS; PROPOFOL; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; RESEARCH DESIGN; TIME FACTORS;

EID: 38849204131     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2007.01560.x     Document Type: Article

References (32)

1. Ginsberg MD. Adventures in the pathophysiology of brain ischemia: penumbra, gene expression, neuroprotection: the 2002 Thomas Willis lecture. Stroke 2003 34 (1) : 214 23.
2. Weinstein PR, Hong SBA, Sharp FR. Molecular identification of the ischemic penumbra. Stroke 2004 35 (11) : 2666 70.
3. Kato H, Kogure K. Biochemical and molecular characteristics of the brain with developing cerebral infarction. Cell Mol Neurobiol 1999 19 (1) : 93 108.
4. Neumar R. Molecular mechanisms of ischemic neuronal injury. Ann Emerg Med 2000 36 (5) : 483 506.
5. Hakim AM. Ischemic penumbra: the therapeutic window. Neurology 1998 51 (Suppl. 3) : S44 6.
6. Charriaut MC, Margaill I, Represa A et al. Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis. J Cereb Blood Flow Metab 1996 16 (2) : 186 95.
7. Graham SH, Chen J. Programmed cell death in cerebral ischemia. J Cereb Blood Flow Metab 2001 21 (2) : 99 109.
8. Li Y, Powers C, Jiang N et al. Intact, injured, necrotic and apoptotic cells after focal cerebral ischemia in the rat. J Neurol Sci 1998 156 : 119 32.
9. Young Y, Menon DK, Tisavipat N et al. Propofol neuroprotection in a rat model of ischemia reperfusion injury. Eur J Anaesthesiol 1997 14 : 320 6.
10. Yamaguchi S, Midorikawa Y, Okuda Y. Propofol prevents delayed neuronal death following transient forebrain ischemia in gerbils. Can J Anaesth 1999 46 : 593 8.
11. Amorim P, Chambers G, Cottrell J et al. Propofol reduces neuronal transmission damage and attenuates the changes in calcium, potassium, and sodium during hyperthermic anoxia in the rat hippocampal slice. Anesthesiology 1995 83 : 1254 65.
12. Velly LJ, Guillet BA, Masmejean FM et al. Neuroprotective effects of propofol in model of ischemic cortical cell cultures: role of glutamate and its transporters. Anesthesiology 2003 99 (2) : 368 75.
13. Yamaguchi S, Hamaguchi S, Mishio M et al. Propofol prevents lipid peroxidation following transient forebrain ischemia in gerbils. Can J Anaesth 2000 47 (10) : 1025 30.
14. Longa EZ, Weinestein PR, Carlson S et al. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989 20 : 84 91.
15. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992 119 : 493 501.
16. Ridenour TR, Warner DS, Todd MM et al. Comparative effects of propofol and halothane on outcome from temporary middle cerebral artery occlusion in the rat. Anesthesiology 1992 76 : 807 12.
17. Pittman JE, Sheng H, Pearlstein R et al. Comparison of the effect of propofol and pentobarbital on neurologic outcome and cerebral infarct size after temporary focal ischemia in the rat. Anesthesiology 1997 87 : 1139 44.
18. Gelb AW, Bayona NA, Wilson JX et al. Propofol anesthesia compared to awake reduces infarct size in rats. Anesthesiology 2002 96 (5) : 1183 90.
19. Bayona NA, Gelb AW, Jiang Z et al. Propofol neuroprotection in cerebral ischemia and its effects on low-molecular-weight antioxidants and skilled motor tasks. Anesthesiology 2004 100 (5) : 1151 9.
20. Zhao W, Belayev L, Ginsberg MD. Transient middle cerebral artery occlusion by intraluminal suture, II. neurological deficits, and pixel-based correlation of histopathology with local blood flow and glucose utilization. J Cereb Blood Flow Metab 1997 17 : 1281 90.
21. Du C, Hu R, Csernansky CA et al. Very delayed infarction after mild focal cerebral ischemia: a role for apoptosis? J Cereb Blood Flow Metab 1996 16 (2) : 195 201.
22. Li Y, Sharor VG, Jiang N. Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery acclusion in the rat. Am J Pathol 1995 146 : 1045 51.
23. Bonfoco E, Krainc D, Ankarcrona M. Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-d-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci USA 1995 92 : 7162 6.
24. Kawaguchi M, Drummond JC, Cole DJ et al. Effect of isoflurane on neuronal apoptosis in rats subjected to focal cerebral ischemia. Anesth Analg 2004 98 (3) : 798 805.
25. Wise-Faberowski L, Raizada M, Sumners C. Oxygen and glucose deprivation-induced neuronal apoptosis is attenuated by halothane and isoflurane. Anesth Analg 2001 93 (5) : 1281 7.
26. Schwartz-Bloom RD, Miller KA, Evenson DA et al. Benzodiazepines protect hippocampal neurons from degeneration after transient cerebral ischemia: an ultrastructural study. Neuroscience 2000 98 (3) : 471 84.
27. Kodaka M, Mori T, Tanaka K et al. Depressive effects of propofol on apoptotic injury and delayed neuronal death after forebrain ischemia in the rat-comparison with nitrous oxide-oxygen-isoflurane. Masui 2000 49 (2) : 130 8.
28. Acquaviva R, Campisi A, Murabito P et al. Propofol attenuates peroxynitrite-mediated DNA damage and apoptosis in cultured astrocytes: an alternative protective mechanism. Anesthesiology 2004 101 (6) : 1363 71.
29. Chen J, Graham SH, Chan PH. Bcl-2 is expressed in neurons that survive from focal ischemia in rat. Neuroreport 1995 6 : 394 8.
30. Chen J, Zhu RL, Nakayama M. Expression of the apoptosis-effector gene, bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia. J Neurochem 1996 67 : 64 71.
31. Engelhard K, Werner C, Eberspacher E et al. Influence of propofol on neuronal damage and apoptotic factors after incomplete cerebral ischemia and reperfusion in rats: a long-term observation. Anesthesiology 2004 101 (4) : 912 7.
32. Engelhard K, Werner C, Eberspacher E et al. Sevoflurane and propofol influence the expression of apoptosis-regulating proteins after cerebral ischaemia and reperfusion in rats. Eur J Anaesthesiol 2004 21 (7) : 530 7.