Depressive effects of propofol on apoptotic injury and delayed neuronal death after forebrain ischemia in the rat -comparison with nitrous oxide-oxygen-isoflurane

Japanese Journal of Anesthesiology

Volumn 49, Issue 2, 2000, Pages 136-138

  Kodaka, Mitsuharu ^a,b   Mori, Takashi ^a   Tanaka, Ken ^a   Nomura, Masahiko ^a   Kawazoe, Taro ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ISOFLURANE; NITROUS OXIDE PLUS OXYGEN; PROPOFOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ARTIFICIAL VENTILATION; BRAIN ISCHEMIA; BRAIN PROTECTION; CAROTID ARTERY OBSTRUCTION; CONTROLLED STUDY; HIPPOCAMPUS; MALE; NERVE CELL NECROSIS; NONHUMAN; RAT;

ANESTHESIA, INHALATION; ANESTHESIA, INTRAVENOUS; ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CELL DEATH; DEPRESSION, CHEMICAL; DISEASE MODELS, ANIMAL; ISOFLURANE; MALE; NITROUS OXIDE; OXYGEN; PROPOFOL; PROSENCEPHALON; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034062046     PISSN: 00214892     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Kock E, Hoffman WE, Werner C, et al : The effects of propofol on brain electrical activity, neurologie outcome, and neuronal damage following incomplete ischemia in rats. Anesthesiology 76 : 245, 1992
2. Ridenour TR, Warner DS, Todd MM, et al : Comparative effects of propofol and halothane on outcome from temporary middle cerebral artery occlusion in the rat. Anesthesiology 76 : 807, 1992
3. Patel PM, Drummond JC, Cole DJ, et al : Isoflurane and pentobarbital reduce the frequency of transient ischémie depolarizations during focal ischemia in rats. Anesth Analg 86: 773, 1998
4. Young Y, Menon DK, Tisavipat N, et al: Propofol neuroprotection in a rat model of ischaemia reperfusion injury. Eur J Anaesthesiol 14 : 320, 1997
5. Nitatori T, Sato N, Waguri S, et al : Delayed neuronal death in the CAl pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J Neurosci 15:1001,1995
6. Li Y, Chopp M, Jiang N, et al : Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats. Stroke 26 :1252, 1995
7. Payan HM, Levine S, Strebel R: Effect of cerebral ischemia in various strains of rats. Proc Soc Exp Biol Med 120 : 208, 1965
8. Smith ML, Bendek G, Dahlgren N, et al: Models for studying long-term recovery following forebrain ischemia in the rat. A 2-vessel occlusion model. Acta Neurol Scand 69: 385, 1984
9. Pulsinelli WA, Brierley TB : A new model of bilateral hemispheric ischemia in the unanesthetized rat. Stroke 10: 267, 1979
10. Amakawa K, Adachi N, Liu K, et al : Effects of pre- and postischemic administration of thiopental on transmitter amino acid release and histologie outcome in gerbils. Anesthesiology 85: 1422, 1996
11. Iwasaki H, Ohmachi Y, Kume E, et al : Strain differences in vulnerability of hippocampal neurons to transient cerebral ischemia in the rat. Int J Exp Path 76: 171, 1995
12. Murphy PG, Myers DS, Davies MJ, et al : The antioxidant potential of propofol (2,6-diisopropylphenol). Br J Anaesth 68 : 613, 1992
13. Illievich UM, Zornow MH, Choi KT, et al: Effects of hypothermia or anesthetics on hippocampal glutamate and glycine concentrations after repeated transient global cerebral ischemia. Anesthesiology 80 : 177, 1994
14. Zhu H, Cottrel JE, Kass IS, et al : The effect of thiopental and propofol on NMDA- and AMPA-mediated glutamate excitotoxicity. Anesthesiology 87: 944,1997
15. Bickler PE, Buck LT, Feiner JR : Volatile and intravenous anesthetics decrease glutamate release from cortical brain slices during anoxia. Anesthesiology 83 : 1233, 1995
16. Diltoer M, Camu F : Glucose homeostasis and insuline secretion during isoflurane anesthesia in human. Anesthesiology 68: 880, 1988