-
1
-
-
0141920370
-
Bench-to-bedside review: Microvascular dysfunction in sepsis - Hemodynamics, oxygen transport, and nitric oxide
-
Bateman RM, Sharpe MD, Ellis CG. Bench-to-bedside review: microvascular dysfunction in sepsis - hemodynamics, oxygen transport, and nitric oxide. Crit Care 2003 7 : 359 73.
-
(2003)
Crit Care
, vol.7
, pp. 359-73
-
-
Bateman, R.M.1
Sharpe, M.D.2
Ellis, C.G.3
-
2
-
-
0037588986
-
The role of endothelium in severe sepsis and multiple organ dysfunction syndrome
-
Aird WC. The role of endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood 2003 101 : 3765 77.
-
(2003)
Blood
, vol.101
, pp. 3765-77
-
-
Aird, W.C.1
-
3
-
-
2942545798
-
Bidirectional relation between inflammation and coagulation
-
Levi M, van der Poll T, Buller HR. Bidirectional relation between inflammation and coagulation. Circulation 2004 109 : 2698 704.
-
(2004)
Circulation
, vol.109
, pp. 2698-704
-
-
Levi, M.1
Van Der Poll, T.2
Buller, H.R.3
-
4
-
-
0031944951
-
Increased microvascular water permeability in patients with septic shock, assessed with venous congestion plethysmography (VCP)
-
Christ F, Gamble J, Gartside IB et al. Increased microvascular water permeability in patients with septic shock, assessed with venous congestion plethysmography (VCP). Intensive Care Med 1998 24 : 18 27.
-
(1998)
Intensive Care Med
, vol.24
, pp. 18-27
-
-
Christ, F.1
Gamble, J.2
Gartside, I.B.3
-
5
-
-
0021963073
-
Increased microvascular permeability: A major cause of hypoalbuminaemia in disease and injury
-
Fleck A, Raines G, Hawker F et al. Increased microvascular permeability: a major cause of hypoalbuminaemia in disease and injury. Lancet 1985 1 : 781 4.
-
(1985)
Lancet
, vol.1
, pp. 781-4
-
-
Fleck, A.1
Raines, G.2
Hawker, F.3
-
7
-
-
27144553471
-
The microcirculation is the motor of sepsis
-
Review.
-
Ince C. The microcirculation is the motor of sepsis. Crit Care 2005 9 : (Suppl. 4) : 13 19. Review.
-
(2005)
Crit Care
, vol.9
, Issue.4
, pp. 13-19
-
-
Ince, C.1
-
8
-
-
4444233598
-
Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock
-
Sakr Y, Dubois MJ, De Backer D et al. Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 2004 32 : 1825 31.
-
(2004)
Crit Care Med
, vol.32
, pp. 1825-31
-
-
Sakr, Y.1
Dubois, M.J.2
De Backer, D.3
-
9
-
-
0025761666
-
Gastrointestinal mucosal injury in experimental models of shock, trauma and sepsis
-
Fink MP. Gastrointestinal mucosal injury in experimental models of shock, trauma and sepsis. Crit Care Med 1991 19 : 627 41.
-
(1991)
Crit Care Med
, vol.19
, pp. 627-41
-
-
Fink, M.P.1
-
10
-
-
0019729432
-
Human protein C: Inactivation of factors V and VIII in plasma by the activated molecule
-
Marlar RA, Kleiss AJ, Griffin JH. Human protein C: inactivation of factors V and VIII in plasma by the activated molecule. Ann NY Acad Sci 1981 370 : 303 10.
-
(1981)
Ann NY Acad Sci
, vol.370
, pp. 303-10
-
-
Marlar, R.A.1
Kleiss, A.J.2
Griffin, J.H.3
-
11
-
-
0025030398
-
Inhibition of thrombus formation by activated recombinant protein C in a primate model of arterial thrombosis
-
Gruber A, Hanson SR, Kelly AB et al. Inhibition of thrombus formation by activated recombinant protein C in a primate model of arterial thrombosis. Circulation 1990 82 : 578 85.
-
(1990)
Circulation
, vol.82
, pp. 578-85
-
-
Gruber, A.1
Hanson, S.R.2
Kelly, A.B.3
-
12
-
-
0021958273
-
Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity
-
Sakata Y, Curriden S, Lawrence D et al. Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity. Proc Natl Acad Sci USA 1985 82 : 1121 5.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 1121-5
-
-
Sakata, Y.1
Curriden, S.2
Lawrence, D.3
-
13
-
-
0021928672
-
Activated protein C decreases plasminogen activator-inhibitor activity in endothelial cell-conditioned medium
-
van Hinsbergh VW, Bertina RM, van Wijngaardern A et al. Activated protein C decreases plasminogen activator-inhibitor activity in endothelial cell-conditioned medium. Blood 1985 65 : 444 51.
-
(1985)
Blood
, vol.65
, pp. 444-51
-
-
Van Hinsbergh, V.W.1
Bertina, R.M.2
Van Wijngaardern, A.3
-
14
-
-
0033830963
-
The anticoagulant and anti-inflammatory roles of the protein C anticoagulant pathway
-
Esmon CT. The anticoagulant and anti-inflammatory roles of the protein C anticoagulant pathway. J Autoimmun 2000 15 : 113 6.
-
(2000)
J Autoimmun
, vol.15
, pp. 113-6
-
-
Esmon, C.T.1
-
15
-
-
3042820686
-
Prevention of endothelial cell injury by activated protein C: The molecular mechanisms and therapeutic implications
-
Okajima K. Prevention of endothelial cell injury by activated protein C: the molecular mechanisms and therapeutic implications. Curr Vasc Pharmacol 2004 2 : 125 33.
-
(2004)
Curr Vasc Pharmacol
, vol.2
, pp. 125-33
-
-
Okajima, K.1
-
16
-
-
13444303827
-
Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model
-
Iba T, Kidokoro A, Fukunaga M et al. Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model. Crit Care Med 2005 33 : 368 72.
-
(2005)
Crit Care Med
, vol.33
, pp. 368-72
-
-
Iba, T.1
Kidokoro, A.2
Fukunaga, M.3
-
17
-
-
34249083323
-
Activated protein C improves intestinal microcirculation in experimental endotoxemia in the rat
-
Lehmann C, Meissner K, knock A et al. Activated protein C improves intestinal microcirculation in experimental endotoxemia in the rat. Crit Care 2006 10 : R157.
-
(2006)
Crit Care
, vol.10
-
-
Lehmann, C.1
Meissner, K.2
Knock, A.3
-
18
-
-
20144389016
-
Recombinant human activated protein C upregulates cyclooxygenase-2 expression in endothelial cells via binding to endothelial cell protein C receptor and activation of protease-activated receptor-I
-
Brueckmann M, Horn S, Lang S et al. Recombinant human activated protein C upregulates cyclooxygenase-2 expression in endothelial cells via binding to endothelial cell protein C receptor and activation of protease-activated receptor-I. Thromb Haemost 2005 93 : 743 50.
-
(2005)
Thromb Haemost
, vol.93
, pp. 743-50
-
-
Brueckmann, M.1
Horn, S.2
Lang, S.3
-
19
-
-
0033810792
-
Protein C levels as a prognostic indicator of outcome in sepsis and related diseases
-
Fisher CJ, Yan SB. Protein C levels as a prognostic indicator of outcome in sepsis and related diseases. Crit Care Med 2000 28 : S49 56.
-
(2000)
Crit Care Med
, vol.28
-
-
Fisher, C.J.1
Yan, S.B.2
-
20
-
-
0034834039
-
Low levels of protein C are associated with poor outcome in severe sepsis
-
Yan BS, Helterbrand JD, Hartman DL et al. Low levels of protein C are associated with poor outcome in severe sepsis. Chest 2001 120 : 915 22.
-
(2001)
Chest
, vol.120
, pp. 915-22
-
-
Yan, B.S.1
Helterbrand, J.D.2
Hartman, D.L.3
-
21
-
-
0035833529
-
Dysfunction of endothelial protein C activation in severe meningococcal sepsis
-
Faust SN, Levin M, Harrison OB et al. Dysfunction of endothelial protein C activation in severe meningococcal sepsis. N Engl J Med 2001 345 : 408 16.
-
(2001)
N Engl J Med
, vol.345
, pp. 408-16
-
-
Faust, S.N.1
Levin, M.2
Harrison, O.B.3
-
23
-
-
0042347994
-
Low utilization of unactivated protein C in a patient with meningococcal septic shock and disseminated intravascular coagulation
-
Lignell A, Siegbahn A, Stridsberg M et al. Low utilization of unactivated protein C in a patient with meningococcal septic shock and disseminated intravascular coagulation. Acta Anaesthesiol Scand 2003 47 : 897 900.
-
(2003)
Acta Anaesthesiol Scand
, vol.47
, pp. 897-900
-
-
Lignell, A.1
Siegbahn, A.2
Stridsberg, M.3
-
24
-
-
0023122016
-
Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon
-
Taylor FB Jr., Chang A, Esmon CT et al. Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon. J Clin Invest 1987 79 : 918 25.
-
(1987)
J Clin Invest
, vol.79
, pp. 918-25
-
-
Taylor Jr., F.B.1
Chang, A.2
Esmon, C.T.3
-
25
-
-
0035826096
-
Recombinant human protein C worldwide evaluation in severe sepsis (PROWESS) study group. Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF et al. Recombinant human protein C worldwide evaluation in severe sepsis (PROWESS) study group. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001 344 : 699 709.
-
(2001)
N Engl J Med
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
-
26
-
-
33747637759
-
Activated protein C (Xigris) treatment in sepsis: A drug in trouble
-
Gårdlund B. Activated protein C (Xigris) treatment in sepsis: a drug in trouble. Acta Anaesthesiol Scand 2006 50 : 907 10.
-
(2006)
Acta Anaesthesiol Scand
, vol.50
, pp. 907-10
-
-
Gårdlund, B.1
-
27
-
-
0018799059
-
The effect of prostacyclin (PGI2) on platelet behaviour. Thrombus formation in vivo and bleeding time
-
Ubatuba FB, Moncada S, Vane JR. The effect of prostacyclin (PGI2) on platelet behaviour. Thrombus formation in vivo and bleeding time. Thromb Haemost 1979 41 : 425 35.
-
(1979)
Thromb Haemost
, vol.41
, pp. 425-35
-
-
Ubatuba, F.B.1
Moncada, S.2
Vane, J.R.3
-
28
-
-
0021363550
-
The effects of prostacyclin on the adhesion of leucocytes to injured vascular endothelium
-
Jones G, Hurley JV. The effects of prostacyclin on the adhesion of leucocytes to injured vascular endothelium. J Pathol 1984 142 : 51 9.
-
(1984)
J Pathol
, vol.142
, pp. 51-9
-
-
Jones, G.1
Hurley, J.V.2
-
30
-
-
0023720167
-
Beneficial effects of prostacyclin in a rabbit endotoxic shock model
-
Ditter H, Matthias FR, Voss R et al. Beneficial effects of prostacyclin in a rabbit endotoxic shock model. Thromb Res 1988 51 : 403 15.
-
(1988)
Thromb Res
, vol.51
, pp. 403-15
-
-
Ditter, H.1
Matthias, F.R.2
Voss, R.3
-
31
-
-
0028034090
-
Effects of prostacyclin analogs on the synthesis of tissue factor, tumor necrosis factor-alfa and interleukin-1-beta in human monocytic THP-1 cells
-
Crutchley JD, Conanan LB, Que BG. Effects of prostacyclin analogs on the synthesis of tissue factor, tumor necrosis factor-alfa and interleukin-1-beta in human monocytic THP-1 cells. J Pharmacol Exp Therap 1994 271 : 446 51.
-
(1994)
J Pharmacol Exp Therap
, vol.271
, pp. 446-51
-
-
Crutchley, J.D.1
Conanan, L.B.2
Que, B.G.3
-
32
-
-
0023101256
-
The clinical significance of prostaglandins and thromboxane as mediators of septic shock
-
Oettinger W, Berger D, Beger HG. The clinical significance of prostaglandins and thromboxane as mediators of septic shock. Klin Wochenschr 1987 65 : 61 8.
-
(1987)
Klin Wochenschr
, vol.65
, pp. 61-8
-
-
Oettinger, W.1
Berger, D.2
Beger, H.G.3
-
33
-
-
0023142761
-
Thromboxane and prostacyclin release in adult respiratory distress syndrome
-
Deby-Dupont G, Braun M, Lamy M et al. Thromboxane and prostacyclin release in adult respiratory distress syndrome. Intensive Care Med 1987 13 : 167 74.
-
(1987)
Intensive Care Med
, vol.13
, pp. 167-74
-
-
Deby-Dupont, G.1
Braun, M.2
Lamy, M.3
-
34
-
-
0035110016
-
Beneficial effects of low-dose prostacyclin on cat intestinal perfusion during endotoxemia as evaluated with microdialysis and oxygen transport variables
-
Möller AD, Grände PO. Beneficial effects of low-dose prostacyclin on cat intestinal perfusion during endotoxemia as evaluated with microdialysis and oxygen transport variables. Crit Care Med 2001 29 : 351 8.
-
(2001)
Crit Care Med
, vol.29
, pp. 351-8
-
-
Möller, A.D.1
Grände, P.O.2
-
35
-
-
0030746484
-
Effects of the stable prostacyclin analogue iloprost on mesenteric blood flow in porcine endotoxic shock
-
Manasia A, Kang H, Hannon E et al. Effects of the stable prostacyclin analogue iloprost on mesenteric blood flow in porcine endotoxic shock. Crit Care Med 1997 25 : 1222 7.
-
(1997)
Crit Care Med
, vol.25
, pp. 1222-7
-
-
Manasia, A.1
Kang, H.2
Hannon, E.3
-
36
-
-
18744424119
-
Role of prostacyclin and nitric oxide in regulation of basal microvascular hydraulic permeability in cat skeletal muscle
-
Möller AD, Grände PO. Role of prostacyclin and nitric oxide in regulation of basal microvascular hydraulic permeability in cat skeletal muscle. J Vasc Res 1999 36 : 245 52.
-
(1999)
J Vasc Res
, vol.36
, pp. 245-52
-
-
Möller, A.D.1
Grände, P.O.2
-
37
-
-
1542286531
-
Low-dose prostacyclin restores an increased protein permeability after trauma in cat skeletal muscle
-
Bentzer P, Grände PO. Low-dose prostacyclin restores an increased protein permeability after trauma in cat skeletal muscle. J Trauma 2004 56 : 385 92.
-
(2004)
J Trauma
, vol.56
, pp. 385-92
-
-
Bentzer, P.1
Grände, P.O.2
-
38
-
-
0033783634
-
Effects of the stable prostacyclin analogue iloprost on the plasma disappearance rate of indocyanine green in human septic shock
-
Lehmann C, Taymoorian K, Wauer H et al. Effects of the stable prostacyclin analogue iloprost on the plasma disappearance rate of indocyanine green in human septic shock. Intensive Care Med 2000 26 : 1557 60.
-
(2000)
Intensive Care Med
, vol.26
, pp. 1557-60
-
-
Lehmann, C.1
Taymoorian, K.2
Wauer, H.3
-
39
-
-
0024214172
-
The therapeutic value of vasodilator prostaglandins in multiple organ failure associated with sepsis
-
Bihari DJ, Tinker J. The therapeutic value of vasodilator prostaglandins in multiple organ failure associated with sepsis. Intensive Care Med 1988 15 : 2 7.
-
(1988)
Intensive Care Med
, vol.15
, pp. 2-7
-
-
Bihari, D.J.1
Tinker, J.2
-
40
-
-
0034896058
-
Hepato-splanchnic metabolic effects of the stable prostacyclin analogue iloprost in patients with septic shock
-
Kiefer P, Tugtekin I, Wiedeck H et al. Hepato-splanchnic metabolic effects of the stable prostacyclin analogue iloprost in patients with septic shock. Intensive Care Med 2001 27 : 1179 86.
-
(2001)
Intensive Care Med
, vol.27
, pp. 1179-86
-
-
Kiefer, P.1
Tugtekin, I.2
Wiedeck, H.3
-
41
-
-
33646800894
-
Evaluation of endotoxin models for the study of sepsis
-
Remick DG, Ward PA. Evaluation of endotoxin models for the study of sepsis. Shock 2005 24 (Suppl. 1) : 7 11.
-
(2005)
Shock
, vol.24
, Issue.1
, pp. 7-11
-
-
Remick, D.G.1
Ward, P.A.2
-
42
-
-
0026537719
-
Regulation of perfused capillary density in canine intestinal mucosa during endotoxemia
-
Drazenovic R, Samsel RW, Wylam ME et al. Regulation of perfused capillary density in canine intestinal mucosa during endotoxemia. J Appl Physiol 1992 72 : 259 65.
-
(1992)
J Appl Physiol
, vol.72
, pp. 259-65
-
-
Drazenovic, R.1
Samsel, R.W.2
Wylam, M.E.3
-
43
-
-
0001583211
-
The behavior of human activated protein C in the plasma of different laboratory animals
-
Chabbat J, Taby O, Toully V et al. The behavior of human activated protein C in the plasma of different laboratory animals. Thromb Haemost 1991 65 : A1814.
-
(1991)
Thromb Haemost
, vol.65
-
-
Chabbat, J.1
Taby, O.2
Toully, V.3
-
44
-
-
33646893270
-
Cardiovascular protective role for activated protein C during endotoxemia in rats
-
Favory R, Lancel S, Marechal X et al. Cardiovascular protective role for activated protein C during endotoxemia in rats. Intensive Care Med 2006 32 : 899 905.
-
(2006)
Intensive Care Med
, vol.32
, pp. 899-905
-
-
Favory, R.1
Lancel, S.2
Marechal, X.3
-
45
-
-
0029802279
-
Aerosolized prostacyclin and inhaled nitric oxide in septic shock - Different effects on splanchnic oxygenation?
-
Eichelbronner O, Reinelt H, Wiedeck H et al. Aerosolized prostacyclin and inhaled nitric oxide in septic shock - different effects on splanchnic oxygenation? Intensive Care Med 1996 22 : 880 7.
-
(1996)
Intensive Care Med
, vol.22
, pp. 880-7
-
-
Eichelbronner, O.1
Reinelt, H.2
Wiedeck, H.3
|