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Volumn 50, Issue 8, 2006, Pages 907-910

Activated protein C (Xigris®) treatment in sepsis: A drug in trouble

Author keywords

Activated Protein C; APC; Drotrecogin alfa; rhAPC; Sepsis; Septic shock; Severe sepsis; Xigris

Indexed keywords

DROTRECOGIN; HYPERTENSIVE AGENT;

EID: 33747637759     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2006.01086.x     Document Type: Article
Times cited : (28)

References (10)
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    • Abraham, E.1    Laterre, P.-F.2    Garg, R.3    Levy, H.4    Talwar, D.5    Trzaskoma, B.L.6
  • 5
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    • Bernard, G.R.1    Macias, W.L.2    Joyce, D.E.3    Williams, M.D.4    Bailey, J.5    Vincent, J.-L.6
  • 7
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    • Recombinant human activated protein C in sepsis: Inconsistent trial results, an unclear mechanism of action, and safety concerns resulting in labeling restrictions and the need for phase IV trials
    • Eichacker PQ, Natanson C. Recombinant human activated protein C in sepsis: Inconsistent trial results, an unclear mechanism of action, and safety concerns resulting in labeling restrictions and the need for phase IV trials. Crit Care Med 2003; 31 (Suppl. 1): S94-S96.
    • (2003) Crit Care Med , vol.31 , Issue.1 SUPPL.
    • Eichacker, P.Q.1    Natanson, C.2
  • 8
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    • Reassessing recombinant human activated protein C for sepsis: Time for a new randomized controlled trial
    • Eichacker PQ, Danner RL, Suffredini AF, Cui X, Natanson C. Reassessing recombinant human activated protein C for sepsis: Time for a new randomized controlled trial. Crit Care Med 2005; 33: 2426-8.
    • (2005) Crit Care Med , vol.33 , pp. 2426-2428
    • Eichacker, P.Q.1    Danner, R.L.2    Suffredini, A.F.3    Cui, X.4    Natanson, C.5
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    • Activated protein C: Do more survive?
    • Mackenzie AF. Activated protein C: do more survive? Intensive Care Med 2005; 31: 1624-6.
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    • A meta-analysis of controlled trials of recombinant human activated protein C therapy in patients with sepsis
    • Wiedermann CJ, Kaneider NC. A meta-analysis of controlled trials of recombinant human activated protein C therapy in patients with sepsis. BMC Emerg Med 2005; 5: 7 [available at. http:/www.biomedcentral.com/1471-227X/5/7 accessed April 29 2006].
    • (2005) BMC Emerg Med , vol.5 , pp. 7
    • Wiedermann, C.J.1    Kaneider, N.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.