메뉴 건너뛰기




Volumn 142, Issue 6, 2007, Pages 679-690

Cytokines and psoriasis: When cytokines become "pathokines"

Author keywords

Cytokines; Psoriasis, diagnosis; Psoriasis, physiopatology

Indexed keywords

ADALIMUMAB; CHEMOKINE; CYTOKINE; ETANERCEPT; GROWTH FACTOR; INFLIXIMAB; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; INTERLEUKIN 23; LYMPHOTOXIN; PLATELET DERIVED GROWTH FACTOR; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

EID: 38849158604     PISSN: 03920488     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (4)

References (117)
  • 1
    • 0035069606 scopus 로고    scopus 로고
    • The impact of psoriasis on quality of life: Results of a 1998 National Psoriasis Foundation patient-membership survey
    • Krueger G, Koo J, Lebwohl M, Menter A, Stern RS, Rolstad T. The impact of psoriasis on quality of life: results of a 1998 National Psoriasis Foundation patient-membership survey. Arch Dermatol 2001;137:280-4.
    • (2001) Arch Dermatol , vol.137 , pp. 280-284
    • Krueger, G.1    Koo, J.2    Lebwohl, M.3    Menter, A.4    Stern, R.S.5    Rolstad, T.6
  • 2
    • 1842790807 scopus 로고    scopus 로고
    • Measures of clinical severity, quality of life, and psychological distress in patients with psoriasis: A cluster analysis
    • Sampogna F, Sera F, Abeni D. Measures of clinical severity, quality of life, and psychological distress in patients with psoriasis: a cluster analysis. J Invest Dermatol 2004;122:602-7.
    • (2004) J Invest Dermatol , vol.122 , pp. 602-607
    • Sampogna, F.1    Sera, F.2    Abeni, D.3
  • 3
    • 0021806161 scopus 로고
    • Psoriasis of early and late onset: Characterization of two types of psoriasis vulgaris
    • Henseler T, Christophers E. Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris. J Am Acad Dermatol 1985;13:450-6.
    • (1985) J Am Acad Dermatol , vol.13 , pp. 450-456
    • Henseler, T.1    Christophers, E.2
  • 4
    • 14244258610 scopus 로고    scopus 로고
    • Psoriasis pathophysiology: Current concepts of pathogenesis
    • Krueger JG, Bowcock A. Psoriasis pathophysiology: current concepts of pathogenesis. Ann Rheum Dis 2005:64 (Suppl 2):ii30-ii36.
    • (2005) Ann Rheum Dis , vol.64 , Issue.SUPPL. 2
    • Krueger, J.G.1    Bowcock, A.2
  • 7
    • 33750400902 scopus 로고    scopus 로고
    • Metabolic disorders in patients with psoriasis and psoriatic arthritis
    • Mallbris L, Ritchlin CT, Stahle M. Metabolic disorders in patients with psoriasis and psoriatic arthritis. Curr Rheumatol Rep 2006;8:355-63.
    • (2006) Curr Rheumatol Rep , vol.8 , pp. 355-363
    • Mallbris, L.1    Ritchlin, C.T.2    Stahle, M.3
  • 8
    • 33645016350 scopus 로고    scopus 로고
    • Psoriasis is associated with lipid abnormalities at the onset of skin disease
    • Mallbris L, Granath F, Hamsten A, Stahle M. Psoriasis is associated with lipid abnormalities at the onset of skin disease. J Am Acad Dermatol 2006;54:614-21.
    • (2006) J Am Acad Dermatol , vol.54 , pp. 614-621
    • Mallbris, L.1    Granath, F.2    Hamsten, A.3    Stahle, M.4
  • 9
    • 33751181855 scopus 로고    scopus 로고
    • Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis
    • Sommer DM, Jenisch S, Suchan M, Christophers E, Weichenthal M. Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Arch Dermatol Res 2006;298:321-28.
    • (2006) Arch Dermatol Res , vol.298 , pp. 321-328
    • Sommer, D.M.1    Jenisch, S.2    Suchan, M.3    Christophers, E.4    Weichenthal, M.5
  • 11
    • 33845465632 scopus 로고    scopus 로고
    • Unfavorable cardiovascular risk profiles in untreated and treated psoriasis patients
    • Wakkee M, Thio HB, Prens EP, Sijbrands EJ, Neumann HA. Unfavorable cardiovascular risk profiles in untreated and treated psoriasis patients. Atherosclerosis 2007;190:1-9.
    • (2007) Atherosclerosis , vol.190 , pp. 1-9
    • Wakkee, M.1    Thio, H.B.2    Prens, E.P.3    Sijbrands, E.J.4    Neumann, H.A.5
  • 13
    • 4344605719 scopus 로고    scopus 로고
    • Lowes MA, Lew W, Krueger JG. Current concepts in the immunopathogenesis of psoriasis. Dermatol Clin 2004;22:349-69,vii.
    • Lowes MA, Lew W, Krueger JG. Current concepts in the immunopathogenesis of psoriasis. Dermatol Clin 2004;22:349-69,vii.
  • 14
    • 33847279025 scopus 로고    scopus 로고
    • Pathogenesis and therapy of psoriasis
    • Lowes MA, Bowcock AM, Krueger JG. Pathogenesis and therapy of psoriasis. Nature 2007;445:866-73.
    • (2007) Nature , vol.445 , pp. 866-873
    • Lowes, M.A.1    Bowcock, A.M.2    Krueger, J.G.3
  • 15
    • 0036239694 scopus 로고    scopus 로고
    • Novel immune-based therapies for psoriasis
    • Kirby B, Griffiths CE. Novel immune-based therapies for psoriasis. Br J Dermatol 2002;146:546-51.
    • (2002) Br J Dermatol , vol.146 , pp. 546-551
    • Kirby, B.1    Griffiths, C.E.2
  • 16
    • 34548536106 scopus 로고    scopus 로고
    • The role of dendritic cells in the immunopathogenesis of psoriasis
    • Jariwala SP. The role of dendritic cells in the immunopathogenesis of psoriasis. Arch Dermatol Res 2007;299:359-66.
    • (2007) Arch Dermatol Res , vol.299 , pp. 359-366
    • Jariwala, S.P.1
  • 17
    • 34548150402 scopus 로고    scopus 로고
    • Angiogenesis and chronic inflammation: Cause or consequence?
    • Costa C, Incio J, Soares R. Angiogenesis and chronic inflammation: cause or consequence? Angiogenesis 2007;10:149-66.
    • (2007) Angiogenesis , vol.10 , pp. 149-166
    • Costa, C.1    Incio, J.2    Soares, R.3
  • 18
    • 0025205232 scopus 로고
    • Lymphocyte adhesion to psoriatic dermal endothelium: Mechanism and modulation
    • Chin YH, Falanga V, Cai JP. Lymphocyte adhesion to psoriatic dermal endothelium: mechanism and modulation. J Invest Dermatol 1990;95:29S-31S.
    • (1990) J Invest Dermatol , vol.95
    • Chin, Y.H.1    Falanga, V.2    Cai, J.P.3
  • 19
    • 28444493712 scopus 로고    scopus 로고
    • Immunopathogenesis of psoriasis: Recent insights on the role of adaptive and innate immunity
    • Bachelez H. Immunopathogenesis of psoriasis: recent insights on the role of adaptive and innate immunity. J Autoimmun 2005;(25 Suppl):69-73.
    • (2005) J Autoimmun , vol.25 , Issue.SUPPL. , pp. 69-73
    • Bachelez, H.1
  • 20
    • 0029150307 scopus 로고
    • Intralesional T-lymphocyte activation as a mediator of psoriatic epidermal hyperplasia
    • Bata-Csorgo Z, Hammerberg C, Voorhees JJ, Cooper KD. Intralesional T-lymphocyte activation as a mediator of psoriatic epidermal hyperplasia. J Invest Dermatol 1995;105:89S-94S.
    • (1995) J Invest Dermatol , vol.105
    • Bata-Csorgo, Z.1    Hammerberg, C.2    Voorhees, J.J.3    Cooper, K.D.4
  • 21
    • 0030716227 scopus 로고    scopus 로고
    • Keratinocytes derived from psoriatic plaques are resistant to apoptosis compared with normal skin
    • Wrone-Smith T, Mitra RS, Thompson CB, Jasty R, Castle VP, Nickoloff BJ. Keratinocytes derived from psoriatic plaques are resistant to apoptosis compared with normal skin. Am J Pathol 1997;151:1321-29.
    • (1997) Am J Pathol , vol.151 , pp. 1321-1329
    • Wrone-Smith, T.1    Mitra, R.S.2    Thompson, C.B.3    Jasty, R.4    Castle, V.P.5    Nickoloff, B.J.6
  • 22
    • 33646552450 scopus 로고    scopus 로고
    • IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis
    • Wolk K, Witte E, Wallace E, Docke WD, Kunz S, Asadullah K et al. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur J Immunol 2006;36:1309-23.
    • (2006) Eur J Immunol , vol.36 , pp. 1309-1323
    • Wolk, K.1    Witte, E.2    Wallace, E.3    Docke, W.D.4    Kunz, S.5    Asadullah, K.6
  • 23
    • 0031012660 scopus 로고    scopus 로고
    • In psoriasis the epidermis, including the subepidermal vascular plexus, grows downwards into the dermis
    • Bacharach-Buhles M, el GS, Panz B, Altmeyer P. In psoriasis the epidermis, including the subepidermal vascular plexus, grows downwards into the dermis. Br J Dermatol 1997;136:97-101.
    • (1997) Br J Dermatol , vol.136 , pp. 97-101
    • Bacharach-Buhles, M.E.G.1    Panz, B.2    Altmeyer, P.3
  • 24
    • 0033387917 scopus 로고    scopus 로고
    • Levels of endothelial cell stimulating angiogenesis factor and vascular endothelial growth factor are elevated in psoriasis
    • Bhushan M, McLaughlin B, Weiss JB, Griffiths CE. Levels of endothelial cell stimulating angiogenesis factor and vascular endothelial growth factor are elevated in psoriasis. Br J Dermatol 1999;141:1054-60.
    • (1999) Br J Dermatol , vol.141 , pp. 1054-1060
    • Bhushan, M.1    McLaughlin, B.2    Weiss, J.B.3    Griffiths, C.E.4
  • 25
    • 0027980960 scopus 로고
    • Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis
    • Detmar M, Brown LF, Claffey KP, Yeo KT, Kocher O, Jackman RW et al. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis. J Exp Med 1994;180:1141-6.
    • (1994) J Exp Med , vol.180 , pp. 1141-1146
    • Detmar, M.1    Brown, L.F.2    Claffey, K.P.3    Yeo, K.T.4    Kocher, O.5    Jackman, R.W.6
  • 26
    • 33847757147 scopus 로고    scopus 로고
    • Cracking the cytokine code in psoriasis
    • Nickoloff BJ. Cracking the cytokine code in psoriasis. Nat Med 2007;13:242-4.
    • (2007) Nat Med , vol.13 , pp. 242-244
    • Nickoloff, B.J.1
  • 27
    • 18044399978 scopus 로고    scopus 로고
    • Psoriasis: The plot thickens
    • Schon MP, Ruzicka T. Psoriasis: the plot thickens. Nat Immunol 2001;2:91.
    • (2001) Nat Immunol , vol.2 , pp. 91
    • Schon, M.P.1    Ruzicka, T.2
  • 28
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver CT, Hatton RD, Mangan PR, Harrington LE. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol 2007;25:821-52.
    • (2007) Annu Rev Immunol , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 29
    • 0031172781 scopus 로고    scopus 로고
    • The Th1/Th2 paradigm
    • Romagnani S. The Th1/Th2 paradigm. Immunol Today 1997;18:263-6.
    • (1997) Immunol Today , vol.18 , pp. 263-266
    • Romagnani, S.1
  • 30
    • 0028179006 scopus 로고
    • Lymphocyte responses and cytokines
    • Paul WE, Seder RA. Lymphocyte responses and cytokines. Cell 1994;76:241-51.
    • (1994) Cell , vol.76 , pp. 241-251
    • Paul, W.E.1    Seder, R.A.2
  • 31
    • 0028201726 scopus 로고
    • Acquisition of lymphokine-producing phenotype by CD4+ T cells
    • Seder RA, Paul WE. Acquisition of lymphokine-producing phenotype by CD4+ T cells. Annu Rev Immunol 1994;12:635-73.
    • (1994) Annu Rev Immunol , vol.12 , pp. 635-673
    • Seder, R.A.1    Paul, W.E.2
  • 32
    • 0035260758 scopus 로고    scopus 로고
    • Chemokines as regulators of T cell differentiation
    • Luther SA, Cyster JG. Chemokines as regulators of T cell differentiation. Nat Immunol 2001;2:102-7.
    • (2001) Nat Immunol , vol.2 , pp. 102-107
    • Luther, S.A.1    Cyster, J.G.2
  • 33
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005;6:345-52.
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 35
    • 33747143361 scopus 로고    scopus 로고
    • From vanilla to 28 flavors: Multiple varieties of T regulatory cells
    • Shevach EM. From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity 2006;25:195-201.
    • (2006) Immunity , vol.25 , pp. 195-201
    • Shevach, E.M.1
  • 36
    • 17944364849 scopus 로고    scopus 로고
    • Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense
    • Ye P. Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. J Exp Med 2001;194:519-27.
    • (2001) J Exp Med , vol.194 , pp. 519-527
    • Ye, P.1
  • 37
    • 0344389016 scopus 로고    scopus 로고
    • Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
    • Matusevicius D. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult Scler 1999;5:101-4.
    • (1999) Mult Scler , vol.5 , pp. 101-104
    • Matusevicius, D.1
  • 38
    • 0033772374 scopus 로고    scopus 로고
    • Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus
    • Wong CK, Ho CY, Li EK, Lam CW. Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus. Lupus 2000;9:589-93.
    • (2000) Lupus , vol.9 , pp. 589-593
    • Wong, C.K.1    Ho, C.Y.2    Li, E.K.3    Lam, C.W.4
  • 39
    • 20844455261 scopus 로고    scopus 로고
    • Comparison of IL-17 production by helper T cells among atopic and nonatopic asthmatics and control subjects
    • Hashimoto T, Akiyama K, Kobayashi N, Mori A. Comparison of IL-17 production by helper T cells among atopic and nonatopic asthmatics and control subjects. Int Arch Allergy Immunol 2005;137:51-4.
    • (2005) Int Arch Allergy Immunol , vol.137 , pp. 51-54
    • Hashimoto, T.1    Akiyama, K.2    Kobayashi, N.3    Mori, A.4
  • 40
    • 0034080842 scopus 로고    scopus 로고
    • Airway neutrophils and interleukin-17
    • Linden A, Hoshino H, Laan M. Airway neutrophils and interleukin-17. Eur Respir J 2000;15:973-7.
    • (2000) Eur Respir J , vol.15 , pp. 973-977
    • Linden, A.1    Hoshino, H.2    Laan, M.3
  • 41
    • 33846906224 scopus 로고    scopus 로고
    • Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
    • Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham-Anderson J, Wu J et al. Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007;445:648-51.
    • (2007) Nature , vol.445 , pp. 648-651
    • Zheng, Y.1    Danilenko, D.M.2    Valdez, P.3    Kasman, I.4    Eastham-Anderson, J.5    Wu, J.6
  • 42
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 2004;22:531-62.
    • (2004) Annu Rev Immunol , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 43
    • 27644565806 scopus 로고    scopus 로고
    • Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity
    • Arican O, Aral M, Sasmaz S, Ciragil P. Serum levels of TNF-alpha, IFN-gamma, IL-6, IL-8, IL-12, IL-17, and IL-18 in patients with active psoriasis and correlation with disease severity. Mediators Inflamm 2005:273-9.
    • (2005) Mediators Inflamm , pp. 273-279
    • Arican, O.1    Aral, M.2    Sasmaz, S.3    Ciragil, P.4
  • 45
    • 27644478613 scopus 로고    scopus 로고
    • The expression of interleukin-17, interferon-gamma, and macrophage inflammatory protein-3 alpha mRNA in patients with psoriasis vulgaris
    • Li J, Li D, Tan Z. The expression of interleukin-17, interferon-gamma, and macrophage inflammatory protein-3 alpha mRNA in patients with psoriasis vulgaris. J Huazhong Univ Sci Technolog Med Sci 2004;24:294-6.
    • (2004) J Huazhong Univ Sci Technolog Med Sci , vol.24 , pp. 294-296
    • Li, J.1    Li, D.2    Tan, Z.3
  • 46
    • 1642369092 scopus 로고    scopus 로고
    • Interleukin-17: A mediator of inflammatory responses
    • Witowski J, Ksiazek K, Jorres A. Interleukin-17: a mediator of inflammatory responses. Cell Mol Life Sci 2004;61:567-79.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 567-579
    • Witowski, J.1    Ksiazek, K.2    Jorres, A.3
  • 47
    • 18144388730 scopus 로고    scopus 로고
    • Update on the mechanisms and efficacy of biological therapies for psoriasis
    • Koo J, Khera P. Update on the mechanisms and efficacy of biological therapies for psoriasis. J Dermatol Sci 2005;38:75-87.
    • (2005) J Dermatol Sci , vol.38 , pp. 75-87
    • Koo, J.1    Khera, P.2
  • 48
    • 0035954670 scopus 로고    scopus 로고
    • Treatment of chronic plaque psoriasis by selective targeting of memory effector T lymphocytes
    • Ellis CN, Krueger GG. Treatment of chronic plaque psoriasis by selective targeting of memory effector T lymphocytes. N Engl J Med 2001;345:248-55.
    • (2001) N Engl J Med , vol.345 , pp. 248-255
    • Ellis, C.N.1    Krueger, G.G.2
  • 49
    • 0036145337 scopus 로고    scopus 로고
    • The immunologic basis for the treatment of psoriasis with new biologic agents
    • Krueger JG. The immunologic basis for the treatment of psoriasis with new biologic agents. J Am Acad Dermatol 2002;46:1-23.
    • (2002) J Am Acad Dermatol , vol.46 , pp. 1-23
    • Krueger, J.G.1
  • 51
    • 0034292333 scopus 로고    scopus 로고
    • Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFN-gamma production by NK-T cells
    • Bonish B, Jullien D, Dutronc Y, Huang BB, Modlin R, Spada FM et al. Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFN-gamma production by NK-T cells. J Immunol 2000;165:4076-85.
    • (2000) J Immunol , vol.165 , pp. 4076-4085
    • Bonish, B.1    Jullien, D.2    Dutronc, Y.3    Huang, B.B.4    Modlin, R.5    Spada, F.M.6
  • 52
    • 10844222790 scopus 로고    scopus 로고
    • Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: Mechanism underlying unrestrained pathogenic effector T cell proliferation
    • Sugiyama H, Gyulai R, Toichi E, Garaczi E, Shimada S, Stevens SR et al. Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation. J Immunol 2005;174:164-73.
    • (2005) J Immunol , vol.174 , pp. 164-173
    • Sugiyama, H.1    Gyulai, R.2    Toichi, E.3    Garaczi, E.4    Shimada, S.5    Stevens, S.R.6
  • 53
    • 0033953110 scopus 로고    scopus 로고
    • CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: Blood and skin comparisons by flow cytometry
    • Ferenczi K, Burack L, Pope M, Krueger JG, Austin LM. CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry. J Autoimmun 2000;14:63-78.
    • (2000) J Autoimmun , vol.14 , pp. 63-78
    • Ferenczi, K.1    Burack, L.2    Pope, M.3    Krueger, J.G.4    Austin, L.M.5
  • 55
    • 0033748019 scopus 로고    scopus 로고
    • Characterization of a T cell line bearing natural killer receptors and capable of creating psoriasis in a SCID mouse model system
    • Nickoloff BJ, Bonish B, Huang BB, Porcelli SA. Characterization of a T cell line bearing natural killer receptors and capable of creating psoriasis in a SCID mouse model system. J Dermatol Sci 2000;24:212-25.
    • (2000) J Dermatol Sci , vol.24 , pp. 212-225
    • Nickoloff, B.J.1    Bonish, B.2    Huang, B.B.3    Porcelli, S.A.4
  • 56
    • 20444497652 scopus 로고    scopus 로고
    • Psoriasis-recent advances in understanding its pathogenesis and treatment
    • Krueger G, Ellis CN. Psoriasis-recent advances in understanding its pathogenesis and treatment. J Am Acad Dermatol 2005;53:S94-100.
    • (2005) J Am Acad Dermatol , vol.53
    • Krueger, G.1    Ellis, C.N.2
  • 57
    • 0036215759 scopus 로고    scopus 로고
    • Psoriatic lesional keratinocytes promote the maturation of human monocyte-derived Langerhans cells
    • Yu Y, Tang L, Wang J, Liu S, Wang W, An H et al. Psoriatic lesional keratinocytes promote the maturation of human monocyte-derived Langerhans cells. Dermatology 2002;204:94-9.
    • (2002) Dermatology , vol.204 , pp. 94-99
    • Yu, Y.1    Tang, L.2    Wang, J.3    Liu, S.4    Wang, W.5    An, H.6
  • 58
    • 3042627000 scopus 로고    scopus 로고
    • Psoriasis vulgaris: An interplay of T lymphocytes, dendritic cells, and inflammatory cytokines in pathogenesis
    • Chamian F, Krueger JG. Psoriasis vulgaris: an interplay of T lymphocytes, dendritic cells, and inflammatory cytokines in pathogenesis. Curr Opin Rheumatol 2004;16:331-7.
    • (2004) Curr Opin Rheumatol , vol.16 , pp. 331-337
    • Chamian, F.1    Krueger, J.G.2
  • 59
    • 0036378060 scopus 로고    scopus 로고
    • Dendritic cells, chemokine receptors and autoimmune inflammatory diseases
    • Cravens PD, Lipsky PE. Dendritic cells, chemokine receptors and autoimmune inflammatory diseases. Immunol Cell Biol 2002;80:497-505.
    • (2002) Immunol Cell Biol , vol.80 , pp. 497-505
    • Cravens, P.D.1    Lipsky, P.E.2
  • 60
    • 3042845754 scopus 로고    scopus 로고
    • Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities
    • Nickoloff BJ, Nestle FO. Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities. J Clin Invest 2004;113:1664-75.
    • (2004) J Clin Invest , vol.113 , pp. 1664-1675
    • Nickoloff, B.J.1    Nestle, F.O.2
  • 62
  • 63
    • 0034917182 scopus 로고    scopus 로고
    • Dendritic cells: Immune saviors or Achilles' heel?
    • Cutler CW, Jotwani R, Pulendran B. Dendritic cells: immune saviors or Achilles' heel? Infect Immun 2001;69:4703-8.
    • (2001) Infect Immun , vol.69 , pp. 4703-4708
    • Cutler, C.W.1    Jotwani, R.2    Pulendran, B.3
  • 64
    • 0034877011 scopus 로고    scopus 로고
    • Psoriasis scales contain C5a as the predominant chemotaxin for monocyte-derived dendritic cells
    • Mrowietz U, Koch WA, Zhu K, Wiedow O, Bartels J, Christophers E et al. Psoriasis scales contain C5a as the predominant chemotaxin for monocyte-derived dendritic cells. Exp Dermatol 2001;10:238-45.
    • (2001) Exp Dermatol , vol.10 , pp. 238-245
    • Mrowietz, U.1    Koch, W.A.2    Zhu, K.3    Wiedow, O.4    Bartels, J.5    Christophers, E.6
  • 66
    • 11144353750 scopus 로고    scopus 로고
    • Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells
    • Hunger RE, Sieling PA, Ochoa MT, Sugaya M, Burdick AE, Rea TH et al. Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells. J Clin Invest 2004;113:701-8.
    • (2004) J Clin Invest , vol.113 , pp. 701-708
    • Hunger, R.E.1    Sieling, P.A.2    Ochoa, M.T.3    Sugaya, M.4    Burdick, A.E.5    Rea, T.H.6
  • 67
    • 0242366614 scopus 로고    scopus 로고
    • Mini-review: Regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross-priming and direct priming?
    • Melief CJ. Mini-review: Regulation of cytotoxic T lymphocyte responses by dendritic cells: peaceful coexistence of cross-priming and direct priming? Eur J Immunol 2003;33:2645-54.
    • (2003) Eur J Immunol , vol.33 , pp. 2645-2654
    • Melief, C.J.1
  • 68
    • 38849118562 scopus 로고    scopus 로고
    • Does IL-6 in psoriatic lesions reverse the ability of regulatory T cells to suppress effector T cell proliferation?
    • Goodman W, Massari J, McCormick T, Cooper K. Does IL-6 in psoriatic lesions reverse the ability of regulatory T cells to suppress effector T cell proliferation? J Invest Dermatol 2007;127:S125.
    • (2007) J Invest Dermatol , vol.127
    • Goodman, W.1    Massari, J.2    McCormick, T.3    Cooper, K.4
  • 69
    • 33846608131 scopus 로고    scopus 로고
    • A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
    • Cargill M, Schrodi SJ, Chang M, Garcia VE, Brandon R, Callis KP et al. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet 2007;80:273-90.
    • (2007) Am J Hum Genet , vol.80 , pp. 273-290
    • Cargill, M.1    Schrodi, S.J.2    Chang, M.3    Garcia, V.E.4    Brandon, R.5    Callis, K.P.6
  • 70
    • 34249039292 scopus 로고    scopus 로고
    • A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis
    • Gottlieb AB, Cooper KD, McCormick TS, Toichi E, Everitt DE, Frederick B et al. A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis. Curr Med Res Opin 2007;23:1081-92.
    • (2007) Curr Med Res Opin , vol.23 , pp. 1081-1092
    • Gottlieb, A.B.1    Cooper, K.D.2    McCormick, T.S.3    Toichi, E.4    Everitt, D.E.5    Frederick, B.6
  • 72
    • 0347285359 scopus 로고    scopus 로고
    • Increased expression of interleukin 23p19 and p40 in lesional skin of patients with psoriasis vulgaris
    • Lee E, Trepicchio WL, Oestreicher JL, Pittman D, Wang F, Chamian F et al. Increased expression of interleukin 23p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 2004;199:125-30.
    • (2004) J Exp Med , vol.199 , pp. 125-130
    • Lee, E.1    Trepicchio, W.L.2    Oestreicher, J.L.3    Pittman, D.4    Wang, F.5    Chamian, F.6
  • 73
    • 33746743044 scopus 로고    scopus 로고
    • Misbehaving macrophages in the pathogenesis of psoriasis
    • Clark RA, Kupper TS. Misbehaving macrophages in the pathogenesis of psoriasis. J Clin Invest 2006;116:2084-7.
    • (2006) J Clin Invest , vol.116 , pp. 2084-2087
    • Clark, R.A.1    Kupper, T.S.2
  • 74
    • 0346096722 scopus 로고    scopus 로고
    • Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model
    • Villadsen LS, Schuurman J, Beurskens F, Dam TN, Gnaes-Hansen F, Skov L et al. Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model. J Clin Invest 2003;112:1571-80.
    • (2003) J Clin Invest , vol.112 , pp. 1571-1580
    • Villadsen, L.S.1    Schuurman, J.2    Beurskens, F.3    Dam, T.N.4    Gnaes-Hansen, F.5    Skov, L.6
  • 75
    • 0034663951 scopus 로고    scopus 로고
    • Inhibition of keratinocyte apoptosis by IL-15: A new parameter in the pathogenesis of psoriasis?
    • Ruckert R, Asadullah K, Seifert M, Budagian VM, Arnold R, Trombotto C et al. Inhibition of keratinocyte apoptosis by IL-15: a new parameter in the pathogenesis of psoriasis? J Immunol 2000;165:2240-50.
    • (2000) J Immunol , vol.165 , pp. 2240-2250
    • Ruckert, R.1    Asadullah, K.2    Seifert, M.3    Budagian, V.M.4    Arnold, R.5    Trombotto, C.6
  • 77
    • 0038306878 scopus 로고    scopus 로고
    • Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation
    • Mascia F, Mariani V, Girolomoni G, Pastore S. Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation. Am J Pathol 2003;163:303-12.
    • (2003) Am J Pathol , vol.163 , pp. 303-312
    • Mascia, F.1    Mariani, V.2    Girolomoni, G.3    Pastore, S.4
  • 78
    • 0034052290 scopus 로고    scopus 로고
    • Response of keratinocytes from normal and psoriatic epidermis to interferon-gamma differs in the expression of zinc-alpha(2)-glycoprotein and cathepsin D
    • Chen SH, Arany I, Apisarnthanarax N, Rajaraman S, Tyring SK, Horikoshi T et al. Response of keratinocytes from normal and psoriatic epidermis to interferon-gamma differs in the expression of zinc-alpha(2)-glycoprotein and cathepsin D. FASEB J 2000;14:565-71.
    • (2000) FASEB J , vol.14 , pp. 565-571
    • Chen, S.H.1    Arany, I.2    Apisarnthanarax, N.3    Rajaraman, S.4    Tyring, S.K.5    Horikoshi, T.6
  • 79
    • 0033999986 scopus 로고    scopus 로고
    • Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin
    • Ting KM, Rothaupt D, McCormick TS, Hammerberg C, Chen G, Gilliam AC et al. Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin. J Invest Dermatol 2000;114:706-11.
    • (2000) J Invest Dermatol , vol.114 , pp. 706-711
    • Ting, K.M.1    Rothaupt, D.2    McCormick, T.S.3    Hammerberg, C.4    Chen, G.5    Gilliam, A.C.6
  • 80
    • 0028928138 scopus 로고
    • Vascular proliferation and angiogenic factors in psoriasis
    • Creamer JD, Barker JN. Vascular proliferation and angiogenic factors in psoriasis. Clin Exp Dermatol 1995;20:6-9.
    • (1995) Clin Exp Dermatol , vol.20 , pp. 6-9
    • Creamer, J.D.1    Barker, J.N.2
  • 81
    • 0028223727 scopus 로고
    • Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis
    • Nickoloff BJ, Mitra RS, Varani J, Dixit VM, Polverini PJ. Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis. Am J Pathol 1994;144:820-8.
    • (1994) Am J Pathol , vol.144 , pp. 820-828
    • Nickoloff, B.J.1    Mitra, R.S.2    Varani, J.3    Dixit, V.M.4    Polverini, P.J.5
  • 83
    • 0029827299 scopus 로고    scopus 로고
    • Differential expression of GRO-alpha and IL-8 mRNA in psoriasis: A model for neutrophil migration and accumulation in vivo
    • Gillitzer R, Ritter U, Spandau U, Goebeler M, Brocker EB. Differential expression of GRO-alpha and IL-8 mRNA in psoriasis: a model for neutrophil migration and accumulation in vivo. J Invest Dermatol 1996;107:778-82.
    • (1996) J Invest Dermatol , vol.107 , pp. 778-782
    • Gillitzer, R.1    Ritter, U.2    Spandau, U.3    Goebeler, M.4    Brocker, E.B.5
  • 84
    • 0025280935 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor in psoriasis
    • Takematsu H, Tagami H. Granulocyte-macrophage colony-stimulating factor in psoriasis. Dermatologica 1990;181:16-20.
    • (1990) Dermatologica , vol.181 , pp. 16-20
    • Takematsu, H.1    Tagami, H.2
  • 85
    • 23444432216 scopus 로고    scopus 로고
    • TNF inhibition rapidly down-regulates multiple proinflammatory pathways in psoriasis plaques
    • Gottlieb AB, Chamian F, Masud S, Cardinale I, Abello MV, Lowes MA et al. TNF inhibition rapidly down-regulates multiple proinflammatory pathways in psoriasis plaques. J Immunol 2005;175:2721-9.
    • (2005) J Immunol , vol.175 , pp. 2721-2729
    • Gottlieb, A.B.1    Chamian, F.2    Masud, S.3    Cardinale, I.4    Abello, M.V.5    Lowes, M.A.6
  • 86
    • 30044435436 scopus 로고    scopus 로고
    • Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
    • Lowes MA, Chamian F, Abello MV, Fuentes-Duculan J, Lin SL, Nussbaum R et al. Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a). Proc Natl Acad Sci U S A 2005;102:19057-62.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 19057-19062
    • Lowes, M.A.1    Chamian, F.2    Abello, M.V.3    Fuentes-Duculan, J.4    Lin, S.L.5    Nussbaum, R.6
  • 87
    • 3342897676 scopus 로고    scopus 로고
    • Interleukin-15: A new cytokine target for the treatment of inflammatory diseases
    • McInnes IB, Gracie JA. Interleukin-15: a new cytokine target for the treatment of inflammatory diseases. Curr Opin Pharmacol 2004;4:392-7.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 392-397
    • McInnes, I.B.1    Gracie, J.A.2
  • 88
    • 2342485676 scopus 로고    scopus 로고
    • Psoriasis vulgaris: Cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression
    • Lew W, Bowcock AM, Krueger JG. Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression. Trends Immunol 2004;25:295-305.
    • (2004) Trends Immunol , vol.25 , pp. 295-305
    • Lew, W.1    Bowcock, A.M.2    Krueger, J.G.3
  • 89
    • 33846940253 scopus 로고    scopus 로고
    • The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis
    • Sa SM, Valdez PA, Wu J, Jung K, Zhong F, Hall L et al. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J Immunol 2007;178:2229-40.
    • (2007) J Immunol , vol.178 , pp. 2229-2240
    • Sa, S.M.1    Valdez, P.A.2    Wu, J.3    Jung, K.4    Zhong, F.5    Hall, L.6
  • 91
    • 10444270993 scopus 로고    scopus 로고
    • Proinflammatory S100 proteins in arthritis and autoimmune disease
    • Foell D, Roth J. Proinflammatory S100 proteins in arthritis and autoimmune disease. Arthritis Rheum 2004;50:3762-71.
    • (2004) Arthritis Rheum , vol.50 , pp. 3762-3771
    • Foell, D.1    Roth, J.2
  • 92
    • 33745035454 scopus 로고    scopus 로고
    • Elevated serum levels of calcium-binding S100 proteins A8 and A9 reflect disease activity and abnormal differentiation of keratinocytes in psoriasis
    • Benoit S, Toksoy A, Ahlmann M, Schmidt M, Sunderkotter C, Foell D et al. Elevated serum levels of calcium-binding S100 proteins A8 and A9 reflect disease activity and abnormal differentiation of keratinocytes in psoriasis. Br J Dermatol 2006;155:62-6.
    • (2006) Br J Dermatol , vol.155 , pp. 62-66
    • Benoit, S.1    Toksoy, A.2    Ahlmann, M.3    Schmidt, M.4    Sunderkotter, C.5    Foell, D.6
  • 94
    • 0031892521 scopus 로고    scopus 로고
    • The human S100 protein MRP-14 is a novel activator of the beta 2 integrin Mac-1 on neutrophils
    • Newton RA, Hogg N. The human S100 protein MRP-14 is a novel activator of the beta 2 integrin Mac-1 on neutrophils. J Immunol 1998;160:1427-35.
    • (1998) J Immunol , vol.160 , pp. 1427-1435
    • Newton, R.A.1    Hogg, N.2
  • 95
    • 0030965068 scopus 로고    scopus 로고
    • Signaling mechanisms and the activation of leukocyte integrins
    • Newton RA, Thiel M, Hogg N. Signaling mechanisms and the activation of leukocyte integrins. J Leukoc Biol 1997;61:422-6.
    • (1997) J Leukoc Biol , vol.61 , pp. 422-426
    • Newton, R.A.1    Thiel, M.2    Hogg, N.3
  • 96
    • 33744997382 scopus 로고    scopus 로고
    • Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events
    • Healy AM, Pickard MD, Pradhan AD, Wang Y, Chen Z, Croce K et al. Platelet expression profiling and clinical validation of myeloid-related protein-14 as a novel determinant of cardiovascular events. Circulation 2006;113:2278-84.
    • (2006) Circulation , vol.113 , pp. 2278-2284
    • Healy, A.M.1    Pickard, M.D.2    Pradhan, A.D.3    Wang, Y.4    Chen, Z.5    Croce, K.6
  • 98
    • 0036621139 scopus 로고    scopus 로고
    • Treatment of psoriasis with the chimeric monoclonal antibody against tumor necrosis factor alpha, infliximab
    • Schopf RE, Aust H, Knop J. Treatment of psoriasis with the chimeric monoclonal antibody against tumor necrosis factor alpha, infliximab. J Am Acad Dermatol 2002;46:886-91.
    • (2002) J Am Acad Dermatol , vol.46 , pp. 886-891
    • Schopf, R.E.1    Aust, H.2    Knop, J.3
  • 99
    • 84898705532 scopus 로고    scopus 로고
    • Increased Expression of the Orphan Nuclear Receptor NURR1 in Psoriasis and Modulation following TNF-alpha Inhibition
    • Aug 2; [Epub ahead of print
    • O'kane M, Markham T, McEvoy AN, Fearon U, Veale DJ, Fitzgerald O et al. Increased Expression of the Orphan Nuclear Receptor NURR1 in Psoriasis and Modulation following TNF-alpha Inhibition. J Invest Dermatol 2007 Aug 2; [Epub ahead of print].
    • (2007) J Invest Dermatol
    • O'kane, M.1    Markham, T.2    McEvoy, A.N.3    Fearon, U.4    Veale, D.J.5    Fitzgerald, O.6
  • 100
  • 102
    • 13844316466 scopus 로고    scopus 로고
    • Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris
    • Chamian F, Lowes MA, Lin SL, Lee E, Kikuchi T, Gilleaudeau P et al. Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris. Proc Natl Acad Sci U S A 2005;102:2075-80.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2075-2080
    • Chamian, F.1    Lowes, M.A.2    Lin, S.L.3    Lee, E.4    Kikuchi, T.5    Gilleaudeau, P.6
  • 103
    • 34548712938 scopus 로고    scopus 로고
    • Influence of psoriatic peripheral blood CD4+ T and CD8+ T lymphocytes on C-myc, Bcl-xL and Ki67 gene expression in keratinocytes
    • Li X, Fan X, Zhang K, Yin G, Liu Y. Influence of psoriatic peripheral blood CD4+ T and CD8+ T lymphocytes on C-myc, Bcl-xL and Ki67 gene expression in keratinocytes. Eur J Dermatol 2007;17:392-6.
    • (2007) Eur J Dermatol , vol.17 , pp. 392-396
    • Li, X.1    Fan, X.2    Zhang, K.3    Yin, G.4    Liu, Y.5
  • 104
    • 33745955321 scopus 로고    scopus 로고
    • Pharmacological interventions for psoriatic arthritis: Present and future
    • Raja Babu KK. Pharmacological interventions for psoriatic arthritis: present and future. Indian J Dermatol Venereol Leprol 2002;68:187-97.
    • (2002) Indian J Dermatol Venereol Leprol , vol.68 , pp. 187-197
    • Raja Babu, K.K.1
  • 106
    • 0036578797 scopus 로고    scopus 로고
    • Biologic therapy for psoriasis: The new therapeutic frontier
    • Singri P, West DP, Gordon KB. Biologic therapy for psoriasis: the new therapeutic frontier. Arch Dermatol 2002;138:657-63.
    • (2002) Arch Dermatol , vol.138 , pp. 657-663
    • Singri, P.1    West, D.P.2    Gordon, K.B.3
  • 107
    • 38849145874 scopus 로고    scopus 로고
    • Biological therapy for psoriasis: Infliximab, etanercept, adalimumab, efalizumab and alefacept
    • Tutrone WD, Weinberg JM. Biological therapy for psoriasis: infliximab, etanercept, adalimumab, efalizumab and alefacept. Expert Rev Dermatol 2006;1:207-16.
    • (2006) Expert Rev Dermatol , vol.1 , pp. 207-216
    • Tutrone, W.D.1    Weinberg, J.M.2
  • 109
    • 34248578489 scopus 로고    scopus 로고
    • Binding characteristics of tumor necrosis factor receptor-Fc fusion proteins vs anti-tumor necrosis factor mAbs
    • Kohno T, Tam LT, Stevens SR, Louie JS. Binding characteristics of tumor necrosis factor receptor-Fc fusion proteins vs anti-tumor necrosis factor mAbs. J Investig Dermatol Symp Proc 2007;12:5-8.
    • (2007) J Investig Dermatol Symp Proc , vol.12 , pp. 5-8
    • Kohno, T.1    Tam, L.T.2    Stevens, S.R.3    Louie, J.S.4
  • 111
    • 34250368782 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor therapies for psoriasis
    • Vena GA, Cassano N. Anti-tumor necrosis factor therapies for psoriasis. Expert Rev Dermatol 2007;2:335-49.
    • (2007) Expert Rev Dermatol , vol.2 , pp. 335-349
    • Vena, G.A.1    Cassano, N.2
  • 112
    • 0035832515 scopus 로고    scopus 로고
    • Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: A randomised trial
    • Chaudhari U, Romano P, Mulcahy LD, Dooley LT, Baker DG, Gottlieb AB. Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trial. Lancet 2001;357:1842-7.
    • (2001) Lancet , vol.357 , pp. 1842-1847
    • Chaudhari, U.1    Romano, P.2    Mulcahy, L.D.3    Dooley, L.T.4    Baker, D.G.5    Gottlieb, A.B.6
  • 113
    • 0037234032 scopus 로고    scopus 로고
    • Pharmacodynamic and pharmacokinetic response to anti-tumor necrosis factor-alpha monoclonal antibody (infliximab) treatment of moderate to severe psoriasis vulgaris
    • Gottlieb AB, Masud S, Ramamurthi R, Abdulghani A, Romano P, Chaudhari U et al. Pharmacodynamic and pharmacokinetic response to anti-tumor necrosis factor-alpha monoclonal antibody (infliximab) treatment of moderate to severe psoriasis vulgaris. J Am Acad Dermatol 2003;48:68-75.
    • (2003) J Am Acad Dermatol , vol.48 , pp. 68-75
    • Gottlieb, A.B.1    Masud, S.2    Ramamurthi, R.3    Abdulghani, A.4    Romano, P.5    Chaudhari, U.6
  • 114
    • 26644433889 scopus 로고    scopus 로고
    • Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: A phase III, multicentre, double-blind trial
    • Reich K, Nestle FO, Papp K, Ortonne JP, Evans R, Guzzo C et al. Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: a phase III, multicentre, double-blind trial. Lancet 2005;366:1367-74.
    • (2005) Lancet , vol.366 , pp. 1367-1374
    • Reich, K.1    Nestle, F.O.2    Papp, K.3    Ortonne, J.P.4    Evans, R.5    Guzzo, C.6
  • 115
    • 33748936662 scopus 로고    scopus 로고
    • Clinical response to adalimumab treatment in patients with moderate to severe psoriasis: Double-blind, randomized controlled trial and open-label extension study
    • Gordon KB, Langley RG, Leonardi C, Toth D, Menter MA, Kang S et al. Clinical response to adalimumab treatment in patients with moderate to severe psoriasis: double-blind, randomized controlled trial and open-label extension study. J Am Acad Dermatol 2006;55:598-606.
    • (2006) J Am Acad Dermatol , vol.55 , pp. 598-606
    • Gordon, K.B.1    Langley, R.G.2    Leonardi, C.3    Toth, D.4    Menter, M.A.5    Kang, S.6
  • 116
    • 33646258473 scopus 로고    scopus 로고
    • Cytokine and anti-cytokine therapies for psoriasis and atopic dermatitis
    • Numerof RP, Asadullah K. Cytokine and anti-cytokine therapies for psoriasis and atopic dermatitis. BioDrugs 2006;20:93-103.
    • (2006) BioDrugs , vol.20 , pp. 93-103
    • Numerof, R.P.1    Asadullah, K.2
  • 117
    • 33749151636 scopus 로고    scopus 로고
    • An anti-IL-12p40 antibody down-regulates type 1 cytokines, chemokines, and IL-12/IL-23 in psoriasis
    • Toichi E, Torres G, McCormick TS, Chang T, Mascelli MA, Kauffman CL et al. An anti-IL-12p40 antibody down-regulates type 1 cytokines, chemokines, and IL-12/IL-23 in psoriasis. J Immunol 2006;177:4917-26.
    • (2006) J Immunol , vol.177 , pp. 4917-4926
    • Toichi, E.1    Torres, G.2    McCormick, T.S.3    Chang, T.4    Mascelli, M.A.5    Kauffman, C.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.