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Volumn 108, Issue 3-5, 2008, Pages 300-309

Neuronal actions of glucocorticoids: Focus on depression

Author keywords

Apoptosis; Depression; Glucocorticoids; Hypothalamo pituitary adrenal axis; Mutant mice; Neuritic atrophy; Neurogenesis; Stress; Transgenic mice

Indexed keywords

ALDOSTERONE; ANTIDEPRESSANT AGENT; CORTICOSTEROID; CORTICOSTEROID RECEPTOR; CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; DEXAMETHASONE; GLUCOCORTICOID; HYDROCORTISONE; MINERALOCORTICOID ANTAGONIST; MINERALOCORTICOID RECEPTOR;

EID: 38749146837     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2007.09.014     Document Type: Article
Times cited : (70)

References (103)
  • 2
    • 33645847829 scopus 로고    scopus 로고
    • The use of mifepristone in the treatment of neuropsychiatric disorders
    • DeBattista C., and Belanoff J. The use of mifepristone in the treatment of neuropsychiatric disorders. Trends Endocrinol. Metab. 17 (2006) 117-121
    • (2006) Trends Endocrinol. Metab. , vol.17 , pp. 117-121
    • DeBattista, C.1    Belanoff, J.2
  • 3
    • 0036212671 scopus 로고    scopus 로고
    • Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs. low CRH/NE states
    • Gold P.W., and Chrousos G.P. Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs. low CRH/NE states. Mol. Psychiatry 7 (2002) 254-275
    • (2002) Mol. Psychiatry , vol.7 , pp. 254-275
    • Gold, P.W.1    Chrousos, G.P.2
  • 4
    • 0033797445 scopus 로고    scopus 로고
    • The corticosteroid receptor hypothesis of depression
    • Holsboer F. The corticosteroid receptor hypothesis of depression. Neuropsychopharmacology 23 (1999) 477-501
    • (1999) Neuropsychopharmacology , vol.23 , pp. 477-501
    • Holsboer, F.1
  • 5
    • 0025729909 scopus 로고
    • Long-term antidepressant administration alters corticotropin-releasing hormone, tyrosine hydroxylase, and mineralocorticoid receptor gene expression in rat brain. Therapeutic implications
    • Brady L.S., Whitfield Jr. H.J., Fox R.J., Gold P.W., and Herkenham M. Long-term antidepressant administration alters corticotropin-releasing hormone, tyrosine hydroxylase, and mineralocorticoid receptor gene expression in rat brain. Therapeutic implications. J. Clin. Invest. 87 (1991) 831-837
    • (1991) J. Clin. Invest. , vol.87 , pp. 831-837
    • Brady, L.S.1    Whitfield Jr., H.J.2    Fox, R.J.3    Gold, P.W.4    Herkenham, M.5
  • 6
    • 19944414033 scopus 로고    scopus 로고
    • Listening to mutant mice: a spotlight on the role of CRF/CRF receptor systems in affective disorders
    • Keck M.E., Ohl F., Holsboer F., and Muller M.B. Listening to mutant mice: a spotlight on the role of CRF/CRF receptor systems in affective disorders. Neurosci. Biobehav. Rev. (2005) 867-889
    • (2005) Neurosci. Biobehav. Rev. , pp. 867-889
    • Keck, M.E.1    Ohl, F.2    Holsboer, F.3    Muller, M.B.4
  • 9
    • 0034193881 scopus 로고    scopus 로고
    • Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated
    • Zobel A.W., Nickel T., Kunzel H.E., Ackl N., Sonntag A., Ising M., and Holsboer F. Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated. J. Psychiatry Res. 34 (2000) 171-181
    • (2000) J. Psychiatry Res. , vol.34 , pp. 171-181
    • Zobel, A.W.1    Nickel, T.2    Kunzel, H.E.3    Ackl, N.4    Sonntag, A.5    Ising, M.6    Holsboer, F.7
  • 11
    • 0036381622 scopus 로고    scopus 로고
    • Corticosteroids: sculptors of the hippocampal formation
    • Sousa N., and Almeida O.F.X. Corticosteroids: sculptors of the hippocampal formation. Rev. Neurosci. 13 (2002) 59-84
    • (2002) Rev. Neurosci. , vol.13 , pp. 59-84
    • Sousa, N.1    Almeida, O.F.X.2
  • 12
    • 38749118384 scopus 로고    scopus 로고
    • Specific configuration of dendritic degeneration in pyramidal neurons of the medial prefrontal cortex induced by differing rorticosteroid regimens
    • (Epub ahead of print)
    • Cerqueira J.J., Taipa R., Uylings H.B., Almeida O.F., and Sousa N. Specific configuration of dendritic degeneration in pyramidal neurons of the medial prefrontal cortex induced by differing rorticosteroid regimens. Cereb. Cortex (2006) (Epub ahead of print)
    • (2006) Cereb. Cortex
    • Cerqueira, J.J.1    Taipa, R.2    Uylings, H.B.3    Almeida, O.F.4    Sousa, N.5
  • 13
    • 1942502215 scopus 로고    scopus 로고
    • Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression
    • pp. 278-286, 224
    • Alonso R., Griebel G., Pavone G., Stemmelin J., Le Fur G., and Soubrie P. Blockade of CRF(1) or V(1b) receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression. Mol. Psychiatry 9 (2004) pp. 278-286, 224
    • (2004) Mol. Psychiatry , vol.9
    • Alonso, R.1    Griebel, G.2    Pavone, G.3    Stemmelin, J.4    Le Fur, G.5    Soubrie, P.6
  • 15
    • 0027081914 scopus 로고
    • Antidepressant drug action in a transgenic mouse model of the endocrine changes seen in depression
    • Pepin M.C., Pothier F., and Barden N. Antidepressant drug action in a transgenic mouse model of the endocrine changes seen in depression. Mol. Pharmacol. 42 (1992) 991-995
    • (1992) Mol. Pharmacol. , vol.42 , pp. 991-995
    • Pepin, M.C.1    Pothier, F.2    Barden, N.3
  • 16
    • 0035659977 scopus 로고    scopus 로고
    • Stress, the immune system and vulnerability to degenerative disorders of the central nervous system in transgenic mice expressing glucocorticoid receptor antisense RNA
    • Marchetti B., Morale M.C., Testa N., Tirolo C., Caniglia S., Amor S., Dijkstra C.D., and Barden N. Stress, the immune system and vulnerability to degenerative disorders of the central nervous system in transgenic mice expressing glucocorticoid receptor antisense RNA. Brain Res. Brain Res. Rev. 37 (2001) 259-272
    • (2001) Brain Res. Brain Res. Rev. , vol.37 , pp. 259-272
    • Marchetti, B.1    Morale, M.C.2    Testa, N.3    Tirolo, C.4    Caniglia, S.5    Amor, S.6    Dijkstra, C.D.7    Barden, N.8
  • 19
    • 12244264438 scopus 로고    scopus 로고
    • Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior
    • Boyle M.P., Brewer J.A., Funatsu M., Wozniak D.F., Tsien J.Z., Izumi Y., and Muglia L.J. Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior. Proc. Acad. Natl. Sci. U.S.A. 102 (2005) 473-478
    • (2005) Proc. Acad. Natl. Sci. U.S.A. , vol.102 , pp. 473-478
    • Boyle, M.P.1    Brewer, J.A.2    Funatsu, M.3    Wozniak, D.F.4    Tsien, J.Z.5    Izumi, Y.6    Muglia, L.J.7
  • 20
    • 0029954339 scopus 로고    scopus 로고
    • TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors
    • Voegel J.J., Heine M.J., Zechel C., Chambon P., and Gronemeyer H. TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors. EMBO J. 15 (1996) 3667-3675
    • (1996) EMBO J. , vol.15 , pp. 3667-3675
    • Voegel, J.J.1    Heine, M.J.2    Zechel, C.3    Chambon, P.4    Gronemeyer, H.5
  • 22
    • 0036311892 scopus 로고    scopus 로고
    • The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP
    • Gehin M., Mark M., Dennefeld C., Dierich A., Gronemeyer H., and Chambon P. The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP. Mol. Cell Biol. 22 (2002) 5923-5937
    • (2002) Mol. Cell Biol. , vol.22 , pp. 5923-5937
    • Gehin, M.1    Mark, M.2    Dennefeld, C.3    Dierich, A.4    Gronemeyer, H.5    Chambon, P.6
  • 24
    • 18044402645 scopus 로고    scopus 로고
    • Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice
    • Gass P., Kretz O., Wolfer D.P., Berger S., Tronche F., Reichardt H.M., Kellendonk C., Lipp H.P., Schmid W., and Schutz G. Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice. EMBO Rep. 1 (2000) 447-451
    • (2000) EMBO Rep. , vol.1 , pp. 447-451
    • Gass, P.1    Kretz, O.2    Wolfer, D.P.3    Berger, S.4    Tronche, F.5    Reichardt, H.M.6    Kellendonk, C.7    Lipp, H.P.8    Schmid, W.9    Schutz, G.10
  • 26
    • 26244468935 scopus 로고    scopus 로고
    • Visualization of glucocorticoid receptor in the brain of green fluorescent protein-glucocorticoid receptor knockin mice
    • Usuku T., Nishi M., Morimoto M., Brewer J.A., Muglia L.J., Sugimoto T., and Kawata M. Visualization of glucocorticoid receptor in the brain of green fluorescent protein-glucocorticoid receptor knockin mice. Neuroscience 135 (2005) 1119-1128
    • (2005) Neuroscience , vol.135 , pp. 1119-1128
    • Usuku, T.1    Nishi, M.2    Morimoto, M.3    Brewer, J.A.4    Muglia, L.J.5    Sugimoto, T.6    Kawata, M.7
  • 27
    • 0022763667 scopus 로고
    • The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis
    • Sapolsky R.M., Krey L.C., and McEwen B.S. The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis. Endocr. Rev. 7 (1986) 284-301
    • (1986) Endocr. Rev. , vol.7 , pp. 284-301
    • Sapolsky, R.M.1    Krey, L.C.2    McEwen, B.S.3
  • 28
    • 1642558899 scopus 로고    scopus 로고
    • Antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex
    • Lucassen P.J., Fuchs E., and Czeh B. Antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex. Biol. Psychiatry 55 (2004) 789-796
    • (2004) Biol. Psychiatry , vol.55 , pp. 789-796
    • Lucassen, P.J.1    Fuchs, E.2    Czeh, B.3
  • 30
    • 0026463945 scopus 로고
    • Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome
    • Starkman M.N., Gebarski S.S., Berent S., and Schteingart D.E. Hippocampal formation volume, memory dysfunction, and cortisol levels in patients with Cushing's syndrome. Biol. Psychiatry 32 (1992) 756-765
    • (1992) Biol. Psychiatry , vol.32 , pp. 756-765
    • Starkman, M.N.1    Gebarski, S.S.2    Berent, S.3    Schteingart, D.E.4
  • 32
    • 0032781059 scopus 로고    scopus 로고
    • Increased cortisol levels and impaired cognition in human aging: implication for depression and dementia in later life
    • Lupien S.J., Nair N.P., Briere S., Maheu F., Tu M.T., Lemay M., McEwen B.S., and Meaney M.J. Increased cortisol levels and impaired cognition in human aging: implication for depression and dementia in later life. Rev. Neurosci. 10 (1999) 117-139
    • (1999) Rev. Neurosci. , vol.10 , pp. 117-139
    • Lupien, S.J.1    Nair, N.P.2    Briere, S.3    Maheu, F.4    Tu, M.T.5    Lemay, M.6    McEwen, B.S.7    Meaney, M.J.8
  • 33
    • 0026781307 scopus 로고
    • Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons
    • Watanabe Y., Gould E., and McEwen B.S. Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. Brain Res. 588 (1992) 341-345
    • (1992) Brain Res. , vol.588 , pp. 341-345
    • Watanabe, Y.1    Gould, E.2    McEwen, B.S.3
  • 34
    • 0024409623 scopus 로고
    • Hippocampal damage associated with prolonged and fatal stress in primates
    • Uno H., Tarara R., Else J.G., Suleman M.A., and Sapolsky R.M. Hippocampal damage associated with prolonged and fatal stress in primates. J. Neurosci. 9 (1989) 1705-1711
    • (1989) J. Neurosci. , vol.9 , pp. 1705-1711
    • Uno, H.1    Tarara, R.2    Else, J.G.3    Suleman, M.A.4    Sapolsky, R.M.5
  • 35
    • 0025168942 scopus 로고
    • Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons
    • Woolley C.S., Gould E., and McEwen B.S. Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons. Brain Res. 531 (1990) 225-231
    • (1990) Brain Res. , vol.531 , pp. 225-231
    • Woolley, C.S.1    Gould, E.2    McEwen, B.S.3
  • 36
    • 0025485399 scopus 로고
    • Hippocampal damage associated with prolonged glucocorticoid exposure in primates
    • Sapolsky R.M., Uno H., Rebert C.S., and Finch C.E. Hippocampal damage associated with prolonged glucocorticoid exposure in primates. J. Neurosci. 10 (1990) 2897-2902
    • (1990) J. Neurosci. , vol.10 , pp. 2897-2902
    • Sapolsky, R.M.1    Uno, H.2    Rebert, C.S.3    Finch, C.E.4
  • 37
    • 23444434948 scopus 로고    scopus 로고
    • Repeated stress and structural plasticity in the brain
    • Radley J.J., and Morrison J.H. Repeated stress and structural plasticity in the brain. Ageing Res. Rev. 4 (2005) 271-287
    • (2005) Ageing Res. Rev. , vol.4 , pp. 271-287
    • Radley, J.J.1    Morrison, J.H.2
  • 38
    • 23944508570 scopus 로고    scopus 로고
    • Morphological correlates of corticosteroid-induced changes in prefrontal cortex-dependent behaviors
    • Cerqueira J.J., Pego J.M., Taipa R., Bessa J.M., Almeida O.F., and Sousa N. Morphological correlates of corticosteroid-induced changes in prefrontal cortex-dependent behaviors. J. Neurosci. 25 (2005) 7792-7800
    • (2005) J. Neurosci. , vol.25 , pp. 7792-7800
    • Cerqueira, J.J.1    Pego, J.M.2    Taipa, R.3    Bessa, J.M.4    Almeida, O.F.5    Sousa, N.6
  • 40
    • 3042855343 scopus 로고    scopus 로고
    • The manifold actions of the protein inhibitor of activated STAT proteins on the transcriptional activity of mineralocorticoid and glucocorticoid receptors in neural cells
    • Tirard M., Jasbinsek J., Almeida O.F.X., and Michaelidis T.M. The manifold actions of the protein inhibitor of activated STAT proteins on the transcriptional activity of mineralocorticoid and glucocorticoid receptors in neural cells. J. Mol. Endocrinol. 32 (2004) 825-841
    • (2004) J. Mol. Endocrinol. , vol.32 , pp. 825-841
    • Tirard, M.1    Jasbinsek, J.2    Almeida, O.F.X.3    Michaelidis, T.M.4
  • 41
    • 1342265730 scopus 로고    scopus 로고
    • DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor-mediated transcription in hippocampal cells-toward a basis for the opposite actions elicited by two nuclear receptors?
    • Obradovic D., Tirard M., Nemethy Z., Hirsch O., Gronemeyer H., and Almeida O.F.X. DAXX, FLASH, and FAF-1 modulate mineralocorticoid and glucocorticoid receptor-mediated transcription in hippocampal cells-toward a basis for the opposite actions elicited by two nuclear receptors?. Mol. Pharmacol. 65 (2004) 761-769
    • (2004) Mol. Pharmacol. , vol.65 , pp. 761-769
    • Obradovic, D.1    Tirard, M.2    Nemethy, Z.3    Hirsch, O.4    Gronemeyer, H.5    Almeida, O.F.X.6
  • 43
    • 0033049428 scopus 로고    scopus 로고
    • Ligand and subfield specificity of corticoid-induced neuronal loss in the rat hippocampal formation
    • Sousa N., Paula-Barbosa M.M., and Almeida O.F.X. Ligand and subfield specificity of corticoid-induced neuronal loss in the rat hippocampal formation. Neuroscience 89 (1999) 1079-1087
    • (1999) Neuroscience , vol.89 , pp. 1079-1087
    • Sousa, N.1    Paula-Barbosa, M.M.2    Almeida, O.F.X.3
  • 44
    • 0025909202 scopus 로고
    • Effects of aldosterone or RU28362 treatment on adrenalectomy-induced cell death in the dentate gyrus of the adult rat
    • Woolley C.S., Gould E., Sakai R.R., Spencer R.L., and McEwen B.S. Effects of aldosterone or RU28362 treatment on adrenalectomy-induced cell death in the dentate gyrus of the adult rat. Brain Res. 554 (1991) 312-315
    • (1991) Brain Res. , vol.554 , pp. 312-315
    • Woolley, C.S.1    Gould, E.2    Sakai, R.R.3    Spencer, R.L.4    McEwen, B.S.5
  • 45
    • 0029054403 scopus 로고
    • Hippocampal dentate granule cell degeneration after adrenalectomy in the rat is not reversed by dexamethasone
    • Sloviter R.S., Sollas A.L., and Neubort S. Hippocampal dentate granule cell degeneration after adrenalectomy in the rat is not reversed by dexamethasone. Brain Res. 682 (1995) 227-230
    • (1995) Brain Res. , vol.682 , pp. 227-230
    • Sloviter, R.S.1    Sollas, A.L.2    Neubort, S.3
  • 46
    • 0033513527 scopus 로고    scopus 로고
    • Corticosterone replacement restores normal morphological features to the hippocampal dendrites, axons and synapses of adrenalectomized rats
    • Sousa N., Madeira M.D., and Paula-Barbosa M.M. Corticosterone replacement restores normal morphological features to the hippocampal dendrites, axons and synapses of adrenalectomized rats. J. Neurocytol. 28 (1999) 541-558
    • (1999) J. Neurocytol. , vol.28 , pp. 541-558
    • Sousa, N.1    Madeira, M.D.2    Paula-Barbosa, M.M.3
  • 47
    • 0030198949 scopus 로고    scopus 로고
    • Exacerbation of apoptosis in the dentate gyrus of the aged rat by dexamethasone and the protective role of corticosterone
    • Hassan A.H., von Rosenstiel P., Patchev V.K., Holsboer F., and Almeida O.F.X. Exacerbation of apoptosis in the dentate gyrus of the aged rat by dexamethasone and the protective role of corticosterone. Exp. Neurol. 140 (1996) 43-52
    • (1996) Exp. Neurol. , vol.140 , pp. 43-52
    • Hassan, A.H.1    von Rosenstiel, P.2    Patchev, V.K.3    Holsboer, F.4    Almeida, O.F.X.5
  • 48
    • 77956672225 scopus 로고    scopus 로고
    • The cellular biology of the stress response
    • Steckler T., Kalin N., and Reul J.M.H.M. (Eds), Elsevier, Amsterdam
    • Lu J., Nemethy Zs., Pego J.M., Cerqueira J.J., Sousa N., and Almeida O.F.X. The cellular biology of the stress response. In: Steckler T., Kalin N., and Reul J.M.H.M. (Eds). Handbook of Stress and the Brain vol. 15 (2005), Elsevier, Amsterdam 729-749
    • (2005) Handbook of Stress and the Brain , vol.15 , pp. 729-749
    • Lu, J.1    Nemethy, Zs.2    Pego, J.M.3    Cerqueira, J.J.4    Sousa, N.5    Almeida, O.F.X.6
  • 49
    • 0032467785 scopus 로고    scopus 로고
    • Brain corticosteroid receptor balance in health and disease
    • de Kloet E.R., Vreugdenhil E., Oitzl M.S., and Joels M. Brain corticosteroid receptor balance in health and disease. Endocr. Rev. 19 (1998) 269-301
    • (1998) Endocr. Rev. , vol.19 , pp. 269-301
    • de Kloet, E.R.1    Vreugdenhil, E.2    Oitzl, M.S.3    Joels, M.4
  • 50
    • 0028133260 scopus 로고
    • Physiological elevations of glucocorticoids potentiate glutamate accumulation in the hippocampus
    • Stein-Behrens B.A., Lin W.J., and Sapolsky R.M. Physiological elevations of glucocorticoids potentiate glutamate accumulation in the hippocampus. J. Neurochem. 63 (1994) 596-602
    • (1994) J. Neurochem. , vol.63 , pp. 596-602
    • Stein-Behrens, B.A.1    Lin, W.J.2    Sapolsky, R.M.3
  • 51
    • 0031024098 scopus 로고    scopus 로고
    • Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro
    • Behl C., Lezoualc'h F., Trapp T., Widmann M., Skutella T., and Holsboer F. Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro. Endocrinology 138 (1997) 101-106
    • (1997) Endocrinology , vol.138 , pp. 101-106
    • Behl, C.1    Lezoualc'h, F.2    Trapp, T.3    Widmann, M.4    Skutella, T.5    Holsboer, F.6
  • 52
    • 23744511289 scopus 로고    scopus 로고
    • Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation
    • Crochemore C., Lu J., Wu Y., Liposits Z., Sousa N., Holsboer F., and Almeida O.F.X. Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation. Mol. Psychiatry 10 (2005) 790-798
    • (2005) Mol. Psychiatry , vol.10 , pp. 790-798
    • Crochemore, C.1    Lu, J.2    Wu, Y.3    Liposits, Z.4    Sousa, N.5    Holsboer, F.6    Almeida, O.F.X.7
  • 53
    • 0042689390 scopus 로고    scopus 로고
    • ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder
    • Muller M.B., Keck M.E., Binder E.B., Kresse A.E., Hagemeyer T.P., Landgraf R., Holsboer F., and Uhr M. ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder. Neuropsychopharmacology 28 (2003) 1991-1999
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1991-1999
    • Muller, M.B.1    Keck, M.E.2    Binder, E.B.3    Kresse, A.E.4    Hagemeyer, T.P.5    Landgraf, R.6    Holsboer, F.7    Uhr, M.8
  • 55
    • 0027293611 scopus 로고
    • Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system
    • Reul J.M., Stec I., Soder M., and Holsboer F. Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system. Endocrinology 133 (1993) 312-320
    • (1993) Endocrinology , vol.133 , pp. 312-320
    • Reul, J.M.1    Stec, I.2    Soder, M.3    Holsboer, F.4
  • 56
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai Z.N., Milliman C.L., and Korsmever S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74 (1993) 609-619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmever, S.J.3
  • 57
    • 33745954330 scopus 로고    scopus 로고
    • Bcl2 faimily in DNA damage and cell cycle control
    • Zinkel S., Gross A., and Yang E. Bcl2 faimily in DNA damage and cell cycle control. Cell Death Differ. 13 (2006) 1351-1359
    • (2006) Cell Death Differ. , vol.13 , pp. 1351-1359
    • Zinkel, S.1    Gross, A.2    Yang, E.3
  • 58
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T., and Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80 (1995) 293-299
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 60
    • 0028849274 scopus 로고
    • p21 is necessary for the p53-mediated G1 arrest in human cancer cells
    • Waldman T., Kinzler K.W., and Vogelstein B. p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 55 (1995) 5187-5190
    • (1995) Cancer Res. , vol.55 , pp. 5187-5190
    • Waldman, T.1    Kinzler, K.W.2    Vogelstein, B.3
  • 62
    • 0028641624 scopus 로고
    • Tumor suppressor p53 induction and DNA damage in hippocampal granule cells after adrenalectomy
    • Schreiber S.S., Sakhi S., Dugich-Djordjevic M.M., and Nichols N.R. Tumor suppressor p53 induction and DNA damage in hippocampal granule cells after adrenalectomy. Exp. Neurol. 130 (1994) 368-376
    • (1994) Exp. Neurol. , vol.130 , pp. 368-376
    • Schreiber, S.S.1    Sakhi, S.2    Dugich-Djordjevic, M.M.3    Nichols, N.R.4
  • 63
    • 0036275355 scopus 로고    scopus 로고
    • Enhancement of p53 activity and inhibition of neural cell proliferation by glucocorticoid receptor activation
    • Crochemore C., Michaelidis T.M., Fischer D., Loeffler J.P., and Almeida O.F.X. Enhancement of p53 activity and inhibition of neural cell proliferation by glucocorticoid receptor activation. FASEB J. 16 (2002) 761-770
    • (2002) FASEB J. , vol.16 , pp. 761-770
    • Crochemore, C.1    Michaelidis, T.M.2    Fischer, D.3    Loeffler, J.P.4    Almeida, O.F.X.5
  • 64
    • 0142091874 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic N-methyl-d-aspartate receptors
    • Lu J., Goula D., Sousa N., and Almeida O.F.X. Ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic N-methyl-d-aspartate receptors. Neuroscience 121 (2003) 123-131
    • (2003) Neuroscience , vol.121 , pp. 123-131
    • Lu, J.1    Goula, D.2    Sousa, N.3    Almeida, O.F.X.4
  • 65
    • 0038147541 scopus 로고    scopus 로고
    • Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression
    • Manji H.K., Quiroz J.A., Sporn J., Payne J.L., Denicoff K., Gray N.A., Zarate Jr. C.A., and Charney D.S. Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biol. Psychiatry 53 (2003) 707-742
    • (2003) Biol. Psychiatry , vol.53 , pp. 707-742
    • Manji, H.K.1    Quiroz, J.A.2    Sporn, J.3    Payne, J.L.4    Denicoff, K.5    Gray, N.A.6    Zarate Jr., C.A.7    Charney, D.S.8
  • 66
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • Nibuya M., Morinobu S., and Duman R.S. Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J. Neurosci. 15 (1995) 7539-7547
    • (1995) J. Neurosci. , vol.15 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 68
    • 33745208951 scopus 로고    scopus 로고
    • A neurotrophic model for stress-related mood disorders
    • Duman R.S., and Monteggia L.M. A neurotrophic model for stress-related mood disorders. Biol. Psychiatry 59 (2006) 1116-1127
    • (2006) Biol. Psychiatry , vol.59 , pp. 1116-1127
    • Duman, R.S.1    Monteggia, L.M.2
  • 69
    • 0037507158 scopus 로고    scopus 로고
    • Reduced phosphorylation of cyclic AMP-responsive element binding protein in the postmortem orbitofrontal cortex of patients with major depressive disorder
    • Yamada S., Yamamoto M., Ozawa H., Riederer P., and Saito T. Reduced phosphorylation of cyclic AMP-responsive element binding protein in the postmortem orbitofrontal cortex of patients with major depressive disorder. J. Neural Transm. 110 (2003) 671-680
    • (2003) J. Neural Transm. , vol.110 , pp. 671-680
    • Yamada, S.1    Yamamoto, M.2    Ozawa, H.3    Riederer, P.4    Saito, T.5
  • 70
    • 0032576396 scopus 로고    scopus 로고
    • Increased temporal cortex CREB concentrations and antidepressant treatment in major depression
    • Dowlatshahi D., MacQueen G.M., Wang J.F., and Young L.T. Increased temporal cortex CREB concentrations and antidepressant treatment in major depression. Lancet 352 (1998) 1754-1755
    • (1998) Lancet , vol.352 , pp. 1754-1755
    • Dowlatshahi, D.1    MacQueen, G.M.2    Wang, J.F.3    Young, L.T.4
  • 71
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • Chen B., Dowlatshahi D., MacQueen G.M., Wang J.F., and Young L.T. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol. Psychiatry 50 (2001) 260-265
    • (2001) Biol. Psychiatry , vol.50 , pp. 260-265
    • Chen, B.1    Dowlatshahi, D.2    MacQueen, G.M.3    Wang, J.F.4    Young, L.T.5
  • 72
    • 23644431529 scopus 로고    scopus 로고
    • The stress system in the human brain in depression and neurodegeneration
    • Swaab D.F., Bao A.M., and Lucassen P.J. The stress system in the human brain in depression and neurodegeneration. Ageing Res. Rev. 4 (2005) 141-194
    • (2005) Ageing Res. Rev. , vol.4 , pp. 141-194
    • Swaab, D.F.1    Bao, A.M.2    Lucassen, P.J.3
  • 73
    • 0037305010 scopus 로고    scopus 로고
    • Improvement in learning associated with increase in hippocampal formation volume
    • Starkman M.N., Giordani B., Gebarski S.S., and Schteingart D.E. Improvement in learning associated with increase in hippocampal formation volume. Biol. Psychiatry 53 (2003) 233-238
    • (2003) Biol. Psychiatry , vol.53 , pp. 233-238
    • Starkman, M.N.1    Giordani, B.2    Gebarski, S.S.3    Schteingart, D.E.4
  • 74
    • 33746279595 scopus 로고    scopus 로고
    • Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment
    • Czeh B., Simon M., Schmelting B., Hiemke C., and Fuchs E. Astroglial plasticity in the hippocampus is affected by chronic psychosocial stress and concomitant fluoxetine treatment. Neuropsychopharmacology 31 (2006) 1616-1626
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1616-1626
    • Czeh, B.1    Simon, M.2    Schmelting, B.3    Hiemke, C.4    Fuchs, E.5
  • 76
    • 0013784893 scopus 로고
    • Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
    • Altman J., and Das G.D. Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J. Comp. Neurol. 124 (1965) 319-335
    • (1965) J. Comp. Neurol. , vol.124 , pp. 319-335
    • Altman, J.1    Das, G.D.2
  • 77
    • 0033306418 scopus 로고    scopus 로고
    • Restoring production of hippocampal neurons in old age
    • Cameron H.A., and McKay R.D. Restoring production of hippocampal neurons in old age. Nat. Neurosci. 2 (1999) 894-897
    • (1999) Nat. Neurosci. , vol.2 , pp. 894-897
    • Cameron, H.A.1    McKay, R.D.2
  • 79
    • 13844299846 scopus 로고    scopus 로고
    • Age-dependent expression of glucocorticoid- and mineralocorticoid receptors on neural precursor cell populations in the adult murine hippocampus
    • Garcia A., Steiner B., Kronenberg G., Bick-Sander A., and Kempermann G. Age-dependent expression of glucocorticoid- and mineralocorticoid receptors on neural precursor cell populations in the adult murine hippocampus. Aging Cell 3 (2004) 363-371
    • (2004) Aging Cell , vol.3 , pp. 363-371
    • Garcia, A.1    Steiner, B.2    Kronenberg, G.3    Bick-Sander, A.4    Kempermann, G.5
  • 80
    • 0032539809 scopus 로고    scopus 로고
    • Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress
    • Gould E., Tanapat P., McEwen B.S., Flugge G., and Fuchs E. Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 3168-3171
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 3168-3171
    • Gould, E.1    Tanapat, P.2    McEwen, B.S.3    Flugge, G.4    Fuchs, E.5
  • 81
    • 3242808933 scopus 로고    scopus 로고
    • Is impaired neurogenesis relevant to the affective symptoms of depression?
    • Sapolsky R.M. Is impaired neurogenesis relevant to the affective symptoms of depression?. Biol. Psychiatry 56 (2004) 137-139
    • (2004) Biol. Psychiatry , vol.56 , pp. 137-139
    • Sapolsky, R.M.1
  • 82
    • 33744498085 scopus 로고    scopus 로고
    • Remodeling of neuronal networks by stress
    • Fuchs E., Flugge G., and Czeh B. Remodeling of neuronal networks by stress. Front. Biosci. 11 (2006) 2746-2758
    • (2006) Front. Biosci. , vol.11 , pp. 2746-2758
    • Fuchs, E.1    Flugge, G.2    Czeh, B.3
  • 83
    • 0028364703 scopus 로고
    • Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus
    • Cameron H.A., and Gould E. Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neuroscience 61 (1994) 203-209
    • (1994) Neuroscience , vol.61 , pp. 203-209
    • Cameron, H.A.1    Gould, E.2
  • 84
    • 5644293601 scopus 로고    scopus 로고
    • Dexamethasone inhibits proliferation of adult hippocampal neurogenesis in vivo and in vitro
    • Kim J.B., Ju J.Y., Kim J.H., Kim T.Y., Yang B.H., Lee Y.S., and Son H. Dexamethasone inhibits proliferation of adult hippocampal neurogenesis in vivo and in vitro. Brain Res. 1027 (2004) 1-10
    • (2004) Brain Res. , vol.1027 , pp. 1-10
    • Kim, J.B.1    Ju, J.Y.2    Kim, J.H.3    Kim, T.Y.4    Yang, B.H.5    Lee, Y.S.6    Son, H.7
  • 85
    • 0026646239 scopus 로고
    • Adrenal hormones suppress cell division in the adult rat dentate gyrus
    • Gould E., Cameron H.A., Daniels D.C., Woolley C.S., and McEwen B.S. Adrenal hormones suppress cell division in the adult rat dentate gyrus. J. Neurosci. 12 (1992) 3642-3650
    • (1992) J. Neurosci. , vol.12 , pp. 3642-3650
    • Gould, E.1    Cameron, H.A.2    Daniels, D.C.3    Woolley, C.S.4    McEwen, B.S.5
  • 86
    • 24144439085 scopus 로고    scopus 로고
    • Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus
    • Wong E.Y., and Herbert J. Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus. Eur. J. Neurosci. 22 (2005) 785-792
    • (2005) Eur. J. Neurosci. , vol.22 , pp. 785-792
    • Wong, E.Y.1    Herbert, J.2
  • 87
    • 0037199798 scopus 로고    scopus 로고
    • The prototypic mineralocorticoid receptor agonist aldosterone influences neurogenesis in the dentate gyrus of the adrenalectomized rat
    • Fischer A.K., von Rosenstiel P., Fuchs E., Goula D., Almeida O.F.X., and Czeh B. The prototypic mineralocorticoid receptor agonist aldosterone influences neurogenesis in the dentate gyrus of the adrenalectomized rat. Brain Res. 947 (2002) 290-293
    • (2002) Brain Res. , vol.947 , pp. 290-293
    • Fischer, A.K.1    von Rosenstiel, P.2    Fuchs, E.3    Goula, D.4    Almeida, O.F.X.5    Czeh, B.6
  • 88
    • 29744434761 scopus 로고    scopus 로고
    • Raised circulating corticosterone inhibits neuronal differentiation of progenitor cells in the adult hippocampus
    • Wong E.Y., and Herbert J. Raised circulating corticosterone inhibits neuronal differentiation of progenitor cells in the adult hippocampus. Neuroscience 137 (2006) 83-92
    • (2006) Neuroscience , vol.137 , pp. 83-92
    • Wong, E.Y.1    Herbert, J.2
  • 89
    • 0242391945 scopus 로고    scopus 로고
    • Reduced cell proliferation in the dentate gyrus is not correlated with the development of learned helplessness
    • Vollmayr B., Simonis C., Weber S., Gass P., and Henn F. Reduced cell proliferation in the dentate gyrus is not correlated with the development of learned helplessness. Biol. Psychiatry 54 (2003) 1035-1040
    • (2003) Biol. Psychiatry , vol.54 , pp. 1035-1040
    • Vollmayr, B.1    Simonis, C.2    Weber, S.3    Gass, P.4    Henn, F.5
  • 90
    • 0141669079 scopus 로고    scopus 로고
    • Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment
    • Malberg J.E., and Duman R.S. Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharmacology 28 (2003) 1562-1571
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1562-1571
    • Malberg, J.E.1    Duman, R.S.2
  • 91
    • 1642499190 scopus 로고    scopus 로고
    • Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible
    • Heine V.M., Maslam S., Zareno J., Joels M., and Lucassen P.J. Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible. Eur. J. Neurosci. 19 (2004) 131-144
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 131-144
    • Heine, V.M.1    Maslam, S.2    Zareno, J.3    Joels, M.4    Lucassen, P.J.5
  • 92
    • 33744998954 scopus 로고    scopus 로고
    • Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitin-mediated degradation of cyclin D1
    • Sundberg M., Savola S., Hienola A., Korhonen L., and Lindholm D. Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitin-mediated degradation of cyclin D1. J. Neurosci. 26 (2006) 5402-5410
    • (2006) J. Neurosci. , vol.26 , pp. 5402-5410
    • Sundberg, M.1    Savola, S.2    Hienola, A.3    Korhonen, L.4    Lindholm, D.5
  • 93
    • 0036358203 scopus 로고    scopus 로고
    • Neurogenesis in adult primate neocortex: an evaluation of the evidence
    • Rakic P. Neurogenesis in adult primate neocortex: an evaluation of the evidence. Nat. Rev. Neurosci. 3 (2002) 65-71
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 65-71
    • Rakic, P.1
  • 94
    • 0035868717 scopus 로고    scopus 로고
    • Neurogenesis in the adult is involved in the formation of trace memories
    • Shors T.J., Miesegaes G., Beylin A., Zhao M., Rydel T., and Gould E. Neurogenesis in the adult is involved in the formation of trace memories. Nature 410 (2001) 372-376
    • (2001) Nature , vol.410 , pp. 372-376
    • Shors, T.J.1    Miesegaes, G.2    Beylin, A.3    Zhao, M.4    Rydel, T.5    Gould, E.6
  • 95
    • 3242745166 scopus 로고    scopus 로고
    • Depression: a case of neuronal life and death?
    • Duman R.S. Depression: a case of neuronal life and death?. Biol. Psychiatry 56 (2004) 140-145
    • (2004) Biol. Psychiatry , vol.56 , pp. 140-145
    • Duman, R.S.1
  • 98
    • 33846877408 scopus 로고    scopus 로고
    • Reduced prefrontal glutamate/glutamine and gamma-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy
    • Hasler G., van der Veen J.W., Tumonis T., Meyers N., Shen J., and Drevets W.C. Reduced prefrontal glutamate/glutamine and gamma-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy. Arch. Gen. Psychiatry 64 (2007) 193-200
    • (2007) Arch. Gen. Psychiatry , vol.64 , pp. 193-200
    • Hasler, G.1    van der Veen, J.W.2    Tumonis, T.3    Meyers, N.4    Shen, J.5    Drevets, W.C.6
  • 99
    • 0035979851 scopus 로고    scopus 로고
    • Differential regulation of forebrain glutamic acid decarboxylase mRNA expression by aging and stress
    • Herman J.P., and Larson B.R. Differential regulation of forebrain glutamic acid decarboxylase mRNA expression by aging and stress. Brain Res. 912 (2001) 60-66
    • (2001) Brain Res. , vol.912 , pp. 60-66
    • Herman, J.P.1    Larson, B.R.2
  • 100
    • 0034667301 scopus 로고    scopus 로고
    • Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells
    • Rajkowska G. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biol. Psychiatry 48 (2000) 766-777
    • (2000) Biol. Psychiatry , vol.48 , pp. 766-777
    • Rajkowska, G.1
  • 101
    • 0036753235 scopus 로고    scopus 로고
    • Low glial numbers in the amygdala in major depressive disorder
    • Bowley M.P., Drevets W.C., Ongur D., and Price J.L. Low glial numbers in the amygdala in major depressive disorder. Biol. Psychiatry 52 (2002) 404-412
    • (2002) Biol. Psychiatry , vol.52 , pp. 404-412
    • Bowley, M.P.1    Drevets, W.C.2    Ongur, D.3    Price, J.L.4
  • 103
    • 30944468498 scopus 로고    scopus 로고
    • Corticosterone-induced inhibition of gliogenesis in rat hippocampus is counteracted by electroconvulsive seizures
    • Wennstrom M., Hellsten J., Ekstrand J., Lindgren H., and Tingstrom A. Corticosterone-induced inhibition of gliogenesis in rat hippocampus is counteracted by electroconvulsive seizures. Biol. Psychiatry 59 (2006) 178-186
    • (2006) Biol. Psychiatry , vol.59 , pp. 178-186
    • Wennstrom, M.1    Hellsten, J.2    Ekstrand, J.3    Lindgren, H.4    Tingstrom, A.5


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