Lumbar nerve root injury induces central nervous system neuroimmune activation and neuroinflammation in the rat: Relationship to painful radiculopathy

Spine

Volumn 27, Issue 15, 2002, Pages 1604-1613

  Rutkowski, Maria D ^a   Winkelstein, Beth A ^a   Hickey, William F ^a   Pahl, Janice L ^a   DeLeo, Joyce A ^a  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

CD4; ICAM 1; Low back pain; MHC Class II; Microglia; PECAM 1; Radiation bone marrow chimeras

Indexed keywords

CD31 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; CD4 ANTIGEN; HLA ANTIGEN CLASS 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; INFLAMMATION; MALE; NERVE ROOT INJURY; NONHUMAN; PRIORITY JOURNAL; RADICULOPATHY; RAT; RAT STRAIN; TACTILE STIMULATION; ANIMAL; BACK; BIOSYNTHESIS; BROWN NORWAY RAT; CELL COUNT; CENTRAL NERVOUS SYSTEM; CROSS BREEDING; DISEASE MODEL; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; IMMUNOMODULATION; INJURY; LEWIS RAT; LOW BACK PAIN; MICROGLIA; NEURITIS; PAIN ASSESSMENT; PATHOLOGY; PATHOPHYSIOLOGY; RADIATION CHIMERA; SPINAL CORD; SPINAL ROOT; SPRAGUE DAWLEY RAT;

ANIMAL; ANTIGENS, CD31; ANTIGENS, CD4; CELL COUNT; CENTRAL NERVOUS SYSTEM; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; HISTOCOMPATIBILITY ANTIGENS CLASS II; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INTERCELLULAR ADHESION MOLECULE-1; LOW BACK PAIN; LUMBOSACRAL REGION; MALE; MICROGLIA; NEURITIS; NEUROIMMUNOMODULATION; PAIN MEASUREMENT; RADIATION CHIMERA; RADICULOPATHY; RATS; RATS, INBRED BN; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; SPINAL CORD; SPINAL NERVE ROOTS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; ANIMALS;

EID: 0036668305     PISSN: 03622436     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007632-200208010-00003     Document Type: Article

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