Hyaluronan oligosaccharides sensitize lymphoma resistant cell lines to vincristine by modulating P-glycoprotein activity and PI3K/Akt pathway

International Journal of Cancer

Volumn 122, Issue 5, 2008, Pages 1012-1018

  Russo, Rosalía I Cordo ^a   García, Mariana G ^a   Alaniz, Laura ^a   Blanco, Guillermo ^a   Alvarez, Elida ^a   Hajos, Silvia E ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Hematological malignancies; Hyaluronan oligosaccharides; Multidrug resistance; P glycoprotein; PI3K Akt

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 3; CYTOTOXIC AGENT; DOXORUBICIN; GLYCOPROTEIN P; HERMES ANTIGEN; HYALURONIC ACID; OLIGOSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SURVIVIN; VINCRISTINE; ANTINEOPLASTIC AGENT; MESSENGER RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; LYMPHOMA; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; DRUG EFFECT; DRUG RESISTANCE; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL LINE, TUMOR; DRUG RESISTANCE, NEOPLASM; HYALURONIC ACID; LYMPHOMA; MICE; OLIGOSACCHARIDES; P-GLYCOPROTEIN; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; VINCRISTINE;

EID: 38749108127     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.23122     Document Type: Article

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