Polarized distribution of IQGAP proteins in gastric parietal cells and their roles in regulated epithelial cell secretion

Molecular Biology of the Cell

Volumn 14, Issue 3, 2003, Pages 1097-1108

  Zhou, Rihong ^a,b   Guo, Zhen ^a   Watson, Charles ^b   Chen, Emily ^b   Kong, Rong ^a   Wang, Wenxian ^a   Yao, Xuebiao ^a,b  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN CDC42; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

ACID SECRETION; ACTIN FILAMENT; ANIMAL CELL; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; CELL POLARITY; CELL SECRETION; CELLULAR DISTRIBUTION; CYTOSKELETON; EPITHELIUM CELL; GENE DISRUPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LOCALIZATION; RABBIT; STOMACH PARIETAL CELL;

ANIMALS; CARRIER PROTEINS; CDC42 GTP-BINDING PROTEIN; CELL MEMBRANE; CELL POLARITY; CYTOSKELETAL PROTEINS; CYTOSKELETON; HUMANS; PARIETAL CELLS, GASTRIC; PEPTIDES; PHOSPHOPROTEINS; PROTEIN BINDING; RABBITS; RAS GTPASE-ACTIVATING PROTEINS; RECOMBINANT FUSION PROTEINS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0037341509     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E02-07-0425     Document Type: Article

References (36)

1. Agnew, B.J., Duman, J.G., Watson, C.J., Coling, D.J., and Forte, J.G. (1999). Cytological transformations associated with parietal cell stimulation: critical steps in the activation cascade, J. Cell Sci. 112, 2639-4266.
2. Ammar, D.A., Zhou, R., Forte, J.G., and X. Yao. (2002) Syntaxin 3 is required for cAMP-induced acid secretion, streptolysin O-permeabilized gastric gland model. Am. J. Physiol. 282, G23-G33.
3. Bishop, A.L., and Hall, A. (2000). Rho GTPases, and their effector proteins. Biochem. J. 348, 241-256.
4. Black, J.A., Forte, T.M., and Forte, J.G. (1982). The effects of microfilament disrupting agents on HCl secretion and ultrastructure of piglet gastric oxyntic cells. Gastroenterology 83, 595-604.
5. Brill, S., Li, S., Lyman, C,W., Church, D.M., Wasmuth, J.J., Weissbach, L., Bernards, A., and Snijders, A.J. (1996). The ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases. Mol. Cell. Biol. 16, 4869-4878.
6. Chen, Y.N., Sharma, S.K., Ramsey, T.M., Jiang, L., Martin, M.S., Baker, K., Adams, P.D., Bair, K.W., and Kaelin, W.G. Jr. (1999). Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists. Proc. Natl. Acad. Sci. USA 96, 4325-4329.
7. Chew, C.S. (1985). Parietal cell protein kinases. Selective activation of type I cAMP-dependent protein kinase by histamine. J. Biol. Chem. 260, 7540-7550.
8. Chew, C.S., Parente, J.A. Jr., Chen, X., Chaponnier, C., and Cameron, R.S. (2000). The LIM, and SH3 domain-containing protein, lasp-1, may link the cAMP signaling pathway with dynamic membrane restructuring activities in ion transporting epithelia. J. Cell Sci. 113, 2035-2045.
9. Drubin, D.G., and Nelson, W.J. (1996). Origins of cell polarity. Cell 84, 335-344.
10. Erickson, J.W., Cerione, R.A., and Hart, M.J. (1997). Identification of an actin cytoskeletal complex that includes IQGAP and the Cdc42 GTPase. J. Biol. Chem. 272, 24443-24447.
11. Feig, L. (1999). Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases. Nat. Cell Biol. 1, E25-E27.
12. Forte, J.G., Black, J.A., Forte, T.M., Machen, T.E., and Wolosin, J.M. (1981). Ultrastructural changes related to functional activity in gastric oxyntic cells. Am. J. Physiol. 241, G349-G358.
13. Forte, T.M., Machen, T.E., and Forte, J.G. (1977). Ultrastructural changes in oxyntic cells associated with secretory function: a membrane-recycling hypothesis. Gastroenterology 73, 941-955.
14. Forte, J.G., and Yao, X. (1996). The Membrane-recruitment-and-recycling hypothesis of gastric HCl secretion. Trends Cell Biol. 6, 45-48.
15. Fukata, M., T. Watanabe, J. Noritake, M. Nakagawa, M. Yamaga, S. Kuroda, Y. Tatsuura, A. Iwamatsu, F. Perez, and Kaibuchi, K. (2002). Rac1 and Cdc42 capture microtubules through IQGAP1 and CLIP-170. Cell 109, 873-885.
16. Guo, W., Roth, D., Walch-Solimena, C., and Novick, P. (1999). The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis. EMBO J. 18, 1071-1081.
17. Hall, A. (1998). Rho GTPases and the actin cytoskeleton. Science 279, 509-514.
18. Hart, M.J., Callow, M.G., Souza, B., and Polakis, P. (1996). IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs. EMBO J. 15, 2997-3005.
19. Helander, H.F., and Sundell, G.W. (1984). Ultrastructure of inhibited parietal cells in the rat. Gastroenterology 87, 1062-1071.
20. Joyal, J.L., Annan, R.S., Ho, Y., Huddleston, M.E., Carr, S.A., Hart, M.J., and Sacks, D.B. (1997). Calmodulin activates phosphatidylinositol 3-kinase. J. Biol. Chem. 272, 15419-15428.
21. Kuroda, S., Fukata, M., Kobayashi, K., Nakafuku, M., Nomura, N., Iwamatsu, A., and Kaibuchi, K. (1996). Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1. J. Biol. Chem. 271, 23363-23367.
22. Li, S., Wang, Q., Chakladar, A., Bronson, R.T., and Bernards, A. (2000). Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1. Mol. Cell. Biol. 20, 697-701.
23. Mackay, D.J., Esch, F., Furthmayr, H., and Hall, A. (1997). Rho- and Rac-dependent assembly of focal adhesion complexes and actin filaments in permeabilized fibroblasts: an essential role for ezrin/radixin/moesin proteins. J. Cell Biol. 138, 927-938.
24. McCallum, S.J., Wu, W.J., and Cerione, R.A. (1996). Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2. J. Biol. Chem. 271, 21732-21737.
25. Rosenfeld, J., Capdevielle, J., Guillemot, J.C., and Ferrara, P. (1992). In-gel digestion of proteins for internal sequence analysis after one-or two-dimensional gel electrophoresis. Anal. Biochem. 203, 173-179.
26. Urushidani, T., Muto, Y., Nagao, T., Yao, X., and Forte, J.G. (1997). ME-3407, a new antiulcer agent, inhibits acid secretion by interfering with redistribution of H(+)-K(+)-ATPase. Am. J. Physiol. 272, G1122-G1134.
27. Verdecia, M.A., Bowman, M.E., Lu, K.P., Hunter, T., and Noel, J.P. (2000). Structural basis for phosphoserine-proline recognition by group IV WW domains. Nat. Struct. Biol. 8, 639-643.
28. Weissbach, L., Settleman, J., Kalady, M.F., Snijders, A.J., Murthy, A.E., Yan, Y.X., and Bernards, A. (1994). Identification of a human rasGAP-related protein containing calmodulin-binding mot. J. Biol. Chem. 269, 20517-20521.
29. Yao, X., and Forte, J.G. (2003). Cell biology of acid secretion by the parietal cell. Annu. Reb. Physiol. 65, 103-131.
30. Yao, X., Anderson, K.L., and Cleveland, D.W. (1997). The microtubule-dependent motor CENP-E is an integral component of kinetochore corora fibers that link centromeres to spindle microtubules. J. Cell Biol. 139, 435-447.
31. Yao, X., Chaponnier, C., Gabbiani, G., and Forte, J.G. (1995). Polarized distribution of actin isoforms in gastric parietal cells. Mol. Biol. Cell 6, 541-557.
32. Yao, X., Cheng, L., and Forre, J.G. (1996a). Biochemical characterization of ezrin-actin interaction. J. Biol. Chem. 271, 7224-7229.
33. Yao, X., Karam, S.M., Ramilo, M., Rong, Q., Thibodeau, A., and Forte, J.G. (1996b). Stimulation of gastric acid secretion by cAMP in a novel α-toxin-permeabilized gland model. Am. J. Physiol. 271, C61-C73.
34. Yao, X., Thibodeau, A., and Forte, J.G. (1993). Ezrin-calpain I interactions in gastric parietal cells. Am. J. Physiol. 265, C36-C46.
35. Zhang, J., Fu, C., Miao, Y., Duo, Z., and Yao, X. (2002). Protein kinase TTK interacts and co-localizes with CENP-E to the kinetochore of human cells. Sci. Bull. 27, 213-219.
36. Zhang, X., Bi, E., Novick, P., Du, L., Kozminski, K.G., Lipschutz, J.H., and Guo, W. (2001). Cdc42 interacts with the exocyst and regulates polarized secretion. J. Biol. Chem. 276, 46745-46750.